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21C Museum Hotel St Louis

4.5 star property
Luxury hotel with fitness centre and steam room

Choose dates to view prices

Photo gallery for 21C Museum Hotel St Louis

Exterior
Bar (on property)
Interior
Billiards
Indoor pool
21C Museum Hotel St Louis stands in the heart of the city, offering travelers a refined experience with its indoor pool and fitness center. Guests can book a massage at the spa, play billiards at the bar, or start their day with a cooked-to-order breakfast at the coffee shop.

Reviews

9.0 out of 10
Wonderful

Popular amenities

  • Pool
  • Bar
  • Spa
  • Gym
  • Room service
The current price is 4.015.391 ₫
4.827.112 ₫ total
includes taxes & fees
21 Sept - 22 Sept

Room options

Check availability for these dates

Tonight

Sept 15 - Sept 16
Check availability for tonight Sept 15 - Sept 16

Tomorrow

Sept 16 - Sept 17
Check availability for tomorrow Sept 16 - Sept 17
Available filters for rooms
Showing 15 of 15 rooms

Loft, 2 Queen Beds

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout curtains
Hairdryer
Bathrobes
  • 40 sq m
  • Sleeps 4
  • 2 Queen Beds

Luxury Suite, 1 King Bed

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout curtains
Separate bath and shower
Private bathroom
  • 51 sq m
  • Sleeps 2
  • 1 King Bed

View all photos for Room (Bunk Bed)

Room (Bunk Bed) | 1 bedroom, in-room safe, desk, laptop workspace

Room (Bunk Bed)

8.0 out of 10
Very good
(6 reviews)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout curtains
Hairdryer
Bathrobes
  • 22 sq m
  • 1 bedroom
  • Sleeps 2
  • 1 Single Bunk Bed

Deluxe Room, Accessible (Accessible)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout curtains
Hairdryer
Bathrobes
  • 25 sq m
  • Sleeps 2
  • 1 King Bed

Suite, 1 King Bed (Library)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout curtains
Hairdryer
Bathrobes
  • 68 sq m
  • City view
  • Sleeps 2
  • 1 King Bed

Suite, 1 King Bed (21C)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout curtains
Separate bath and shower
Private bathroom
  • 104 sq m
  • Sleeps 2
  • 1 King Bed

Deluxe Room, 1 Double Bed, Accessible

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout curtains
Hairdryer
Bathrobes
  • 36 sq m
  • Sleeps 4
  • 1 Double Bed

View all photos for Deluxe Room, 1 King Bed

Deluxe Room, 1 King Bed | 1 bedroom, in-room safe, desk, laptop workspace

Deluxe Room, 1 King Bed

9.2 out of 10
Wonderful
(72 reviews)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout curtains
Hairdryer
Bathrobes
  • 29 sq m
  • Sleeps 2
  • 1 King Bed

Deluxe Suite, 1 Double Bed, Accessible

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout curtains
Hairdryer
Bathrobes
  • 48 sq m
  • Sleeps 2
  • 1 Double Bed

View all photos for Deluxe Double Room, 2 Queen Beds

1 bedroom, in-room safe, desk, laptop workspace

Deluxe Double Room, 2 Queen Beds

8.6 out of 10
Excellent
(20 reviews)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout curtains
Shower/bath combination
Private bathroom
  • 34 sq m
  • Sleeps 4
  • 2 Queen Beds

Deluxe Room, 1 Double Bed, Accessible

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout curtains
Hairdryer
Bathrobes
  • 36 sq m
  • Sleeps 4
  • 1 Double Bed

View all photos for Room, 1 King Bed, Corner

Room, 1 King Bed, Corner | 1 bedroom, in-room safe, desk, laptop workspace

Room, 1 King Bed, Corner

8.8 out of 10
Excellent
(25 reviews)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout curtains
Hairdryer
Bathrobes
  • 30 sq m
  • City view
  • Sleeps 2
  • 1 King Bed

View all photos for Suite, 1 King Bed

1 bedroom, in-room safe, desk, laptop workspace

Suite, 1 King Bed

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout curtains
Hairdryer
Bathrobes
  • 48 sq m
  • Sleeps 2
  • 1 King Bed

View all photos for Deluxe Suite, 1 King Bed

1 bedroom, in-room safe, desk, laptop workspace

Deluxe Suite, 1 King Bed

9.2 out of 10
Wonderful
(5 reviews)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout curtains
Hairdryer
Bathrobes
  • 48 sq m
  • Sleeps 2
  • 1 King Bed

View all photos for Luxury Double Room, 2 Queen Beds

1 bedroom, in-room safe, desk, laptop workspace

Luxury Double Room, 2 Queen Beds

9.2 out of 10
Wonderful
(21 reviews)

Highlights

Soundproofed
Air conditioning
Heating
Flat-screen TV
Separate bedroom
Blackout curtains
Shower/bath combination
Private bathroom
  • 39 sq m
  • Sleeps 4
  • 2 Queen Beds

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Exterior

Fairfield Inn & Suites St Louis Westport

Maryland Heights
  • Pool
  • Breakfast included
  • Free WiFi
  • Air conditioning
9.2 out of 10, Wonderful, 791 reviews
The price is 3.342.420 ₫
3.876.807 ₫ total
includes taxes & fees
21 Sept - 22 Sept
Fairfield Inn & Suites St Louis Westport
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About the area

Located in St. Louis, 21C Museum Hotel St Louis is in the city centre. St. Louis Union Station and Gateway Arch are notable landmarks, and the area's natural beauty can be seen at Mississippi River and Forest Park. Check out an event or a game at Busch Stadium, and consider making time for St. Louis Zoo, a top attraction not to be missed.
Visit our St. Louis travel guideOpens in a new window
Map
1528 Locust street, St. Louis, MO, 63103

What's nearby

  • St. Louis Union Station - 6 min walk - 0.6 km
  • Enterprise Center - 6 min walk - 0.6 km
  • City Museum - 6 min walk - 0.6 km
  • Busch Stadium - 14 min walk - 1.2 km
  • Gateway Arch - 2 min drive - 1.8 km

Getting around

  • 8th and Pine Station - 13 min walk
  • St. Louis Gateway Station - 14 min walk
  • Lambert-St. Louis International Airport (STL) - 26 min drive

Restaurants

  • ‪Budweiser Kiel Club - ‬6 min walk
  • ‪City Museum Rooftop Cafe - ‬5 min walk
  • ‪Medina Grill - ‬5 min walk
  • ‪Blood & Sand - ‬2 min walk
  • ‪White Knight Diner - ‬4 min walk

About this property

21C Museum Hotel St Louis

Luxury hotel near Enterprise Center
Located close to St. Louis Union Station and Busch Stadium, 21C Museum Hotel St Louis provides a coffee shop/cafe, dry cleaning/laundry services and a bar. Treat yourself to a massage or other spa services. In addition to a gym and a business centre, guests can connect to free in-room WiFi.
You'll also enjoy the following perks during your stay:
  • An indoor pool
  • Cooked-to-order breakfast (surcharge), valet parking (surcharge) and a vending machine
  • Luggage storage, a banquet hall and concierge services
  • ATM/banking services, meeting rooms and smoke-free property
  • Guest reviews say great things the dining options, pool and helpful staff
Room features
All 104 rooms include comforts such as laptop-friendly workspaces and air conditioning, as well as perks such as free WiFi and desk chairs. Guest reviews highly rate the cleanliness rooms at the property.
More amenities include:
  • Free toiletries and hairdryers
  • Flat-screen TVs with premium channels
  • Wardrobes/cupboards, heating and daily housekeeping

Property amenities

Internet

  • Available in all rooms: Free WiFi
  • Available in some public areas: Free WiFi

Parking and transport

  • Valet parking on site (USD 50 per day; includes in/out privileges)

Food and drink

  • Daily cooked-to-order breakfast available 6:30 AM to 1:00 PM for a fee: USD 10 to 25 per person
  • A bar/lounge
  • A coffee shop/cafe
  • A restaurant

Things to do

  • Billiards/pool table
  • Gym
  • Indoor pool
  • Steam room

Family friendly

  • Indoor pool
  • Soundproofed rooms

Conveniences

  • 24-hour front desk
  • ATM
  • Luggage storage
  • Vending machine

Guest services

  • Change of bedsheets (on request)
  • Change of towels on request
  • Concierge services
  • Dry cleaning/laundry service
  • Housekeeping (daily)

Business services

  • Business centre
  • Meeting rooms

Spa

  • Massage
  • Spa services

Accessibility

  • If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
  • Area rugs in room
  • Braille/raised signage
  • Grab bar in shower (89 centimetre high)
  • Handrails in stairways (91 centimetre high)
  • Lever door handles
  • Lift (107 centimetre wide door)
  • Magnifying mirror
  • Pool hoist on site
  • Stair-free path to entrance
  • Thin carpet in room
  • Tile flooring in room
  • Visual fire alarm
  • Well-lit path to entrance
  • Wheelchair accessible (may have limitations)
  • Wheelchair-accessible gym
  • Wheelchair-accessible lounge
  • Wheelchair-accessible path of travel
  • Wheelchair-accessible pool
  • Wheelchair-accessible public bathroom
  • Wheelchair-accessible registration desk (91 centimetre high)
  • Wheelchair-accessible restaurant
  • Wheelchair-accessible spa
  • Wheelchairs on site

More

  • Banquet hall
  • Biodegradable coffee stirrers available
  • Biodegradable drinking straws available
  • No plastic coffee stirrers
  • No plastic drinking straws
  • No plastic soft drink bottles
  • No plastic water bottles
  • Reusable cups
  • Reusable tableware
  • Smoke-free property

Room amenities

Bedroom

  • Bedsheets provided
  • Blackout drapes

Bathroom

  • Dressing gowns
  • Free toiletries
  • Hair dryer
  • Shampoo
  • Soap
  • Toilet paper
  • Toothbrush and toothpaste (on request)
  • Towels provided

Entertainment

  • Flat-screen TV with premium digital channels

Food and drink

  • Espresso maker
  • Free bottled water
  • Limited room service

More

  • Air conditioning
  • Desk
  • Desk chair
  • Heating
  • Iron/ironing board
  • Laptop workspace
  • Phone
  • Safe
  • Soundproofed rooms

Policies

Check-in

Check-in start time: 4:00 PM; check-in end time: 11:00 AM
Late check-in subject to availability
Minimum check-in age - 21

Check-out

Check-out before 11:00 AM

Special check-in instructions

Front desk staff will greet guests on arrival at the property

Access methods

Staffed front desk

Pets

Pets are allowed for an extra charge of USD 100 per accommodation, per stay
Service animals are welcome, and are exempt from fees
Welcoming dogs only

Children and extra beds

Children are welcome
Rollaway/extra beds are not available.
Cots (infant beds) are not available

Payment types at the property

Important information

Fees

You'll be asked to pay the following charges at the property. Fees may include applicable taxes:

  • Service fee: USD 5 per accommodation, per stay

We have included all charges provided to us by the property.

Optional extras

  • Fee for cooked-to-order breakfast: approximately USD 10 to 25 per person
  • Valet parking fee: USD 50 per day (in/out privileges)
  • Pet fee: USD 100 per accommodation, per stay
  • Service animals are exempt from fees

The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
This property accepts credit cards; cash is not accepted
Safety features at this property include a smoke detector and outdoor lighting

We should mention

Reservations are required for massage services; reservations can be made by contacting the property prior to arrival, using the contact information on the booking confirmation
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly)

Property is also known as

21C Museum Hotel St Louis
21c Museum St Louis St Louis
21C Museum Hotel St Louis Hotel
21C Museum Hotel St Louis St. Louis
21C Museum Hotel St Louis Hotel St. Louis
21C Museum Hotel St Louis (Opening Spring 2023)

Frequently asked questions

Does 21C Museum Hotel St Louis have a pool?

Yes, this property has an indoor pool.

How much does it cost to stay at 21C Museum Hotel St Louis ?

As of 15 Sep 2025, prices found for a 1-night stay for 2 adults at 21C Museum Hotel St Louis on 21 Sep 2025 start from 4.015.391 ₫, excluding taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

Is 21C Museum Hotel St Louis pet-friendly?

Yes, dogs are allowed at this property. There's a fee of USD 100 per accommodation, per stay. Service animals are exempt from fees.

How much is parking at 21C Museum Hotel St Louis ?

Valet parking is available for USD 50 per day.

What time is check-in at 21C Museum Hotel St Louis ?

Check-in start time: 4:00 PM; check-in end time: 11:00 AM. Late check-in is available during limited hours.

What time is check-out at 21C Museum Hotel St Louis ?

Checkout is at 11:00 AM.

Where is 21C Museum Hotel St Louis located?

Located in Downtown West, this luxury hotel is within a 10-minute walk of Washington Avenue Historic District, City Museum, and Enterprise Center. St. Louis Union Station and America's Center Convention Complex are also within 15 minutes. 8th and Pine Station is 13 minutes by foot and Convention Center Station is 16 minutes.

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Reviews

21C Museum Hotel St Louis Reviews

9.0

Wonderful

9.2

Cleanliness

9.2

Amenities

9.2

Staff & service

9.2

Eco-friendliness

9.4

Property conditions & facilities
Rating 10 - Excellent. 992 out of 1370 reviews
Rating 8 - Good. 201 out of 1370 reviews
Rating 6 - Okay. 86 out of 1370 reviews
Rating 4 - Poor. 41 out of 1370 reviews
Rating 2 - Terrible. 50 out of 1370 reviews

Reviews

10/10 Excellent

Reginald

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Nice place
Stayed 3 nights in Sep 2025

10/10 Excellent

Angela

Liked: Cleanliness, staff & service, property conditions & facilities
Amazing hotel!
Stayed 1 night in Aug 2025

10/10 Excellent

Benjamin

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Amazing pool, great food and drink options, terrific staff.
Stayed 1 night in Aug 2025

10/10 Excellent

Casey

Liked: Amenities, property conditions & facilities
Amazing staff, clean!
Stayed 1 night in Sep 2025

10/10 Excellent

Stephen

Liked: Cleanliness, staff & service, property conditions & facilities
Very interesting property. Enjoyed the stay.
Stayed 1 night in Sep 2025

10/10 Excellent

Thomas

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Excellent hotel. Very unique, good vibes.
Stayed 3 nights in Aug 2025

10/10 Excellent

Lisa

Liked: Cleanliness, staff & service, property conditions & facilities
Stay here often!
Stayed 1 night in Aug 2025

10/10 Excellent

Rachel

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Love the art at the hotel.
Stayed 1 night in Aug 2025

10/10 Excellent

Kerry

Liked: Cleanliness, amenities
Great idea with the museum, fantastic older building with so much chsracter.
Stayed 1 night in Aug 2025

10/10 Excellent

margaret

Liked: Amenities
Fantastic property with great device
Stayed 1 night in Sep 2025

10/10 Excellent

Amanda

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Beautiful hotel and great food options. Gym and pool were great also.
Stayed 1 night in Aug 2025

10/10 Excellent

Patricia

Liked: Cleanliness, staff & service, property conditions & facilities
Fun place to stay. Museum on the 2nd floor was so much fun.
Stayed 1 night in Aug 2025

10/10 Excellent

Jeffrey

Liked: Cleanliness
Great place to stay.
Stayed 1 night in Jun 2025

8/10 Good

Lee

Liked: Cleanliness, staff & service, property conditions & facilities
Nice hotel but the area wasn’t the best
Stayed 3 nights in Aug 2025

10/10 Excellent

rebecca

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
It was a great location
Stayed 1 night in Jun 2025

10/10 Excellent

Matthew

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Always enjoy staying at this hotel. Staff is always willing to lend a hand. Love the pool, art, and other amenities.
Stayed 2 nights in Jun 2025

10/10 Excellent

Shamiyer

I loved my stay the room was perfect and very comfortable and clean
Stayed 1 night in Jul 2025

10/10 Excellent

Lima Rose

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Great stay
Stayed 1 night in Jun 2025

10/10 Excellent

Nicole

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
This hotel was absolutely beautiful and so unique. The staff was so amazing and friendly, and the rooms were beautiful. We will definitely be repeat guests.
Stayed 3 nights in Jul 2025

10/10 Excellent

Will

Liked: Cleanliness, amenities, property conditions & facilities
Great place, decor, art, and people
Stayed 2 nights in Jun 2025

10/10 Excellent

Leslie

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Wonderful hotel in a historic YMCA building downtown. First class interiors, art collection, ambiance, and rooms. The room was small but well appointed. Very quiet. All amenities (no microwave), including wonderful Italian coffee machine. We also had an amazing cocktail hour with the bartender in the lobby. He knows his craft very well. We’ll be starting here often in the future.
Stayed 2 nights in Sep 2025

10/10 Excellent

Mary

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Loved this hotel!
Stayed 1 night in Jun 2025

6/10 Okay

Nicole

Disliked: Staff & service
An okay area. Our body was was never refilled and when asking about early check in I spoke with 3 different people who all told me different things.
Stayed 2 nights in Sep 2025

10/10 Excellent

Sarah

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Loved the art and the building itself. Bed sheets weren’t as clean and the pillows weren’t comfortable. The towels in the bathroom were frayed.
Stayed 1 night in Sep 2025

10/10 Excellent

Jessica

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The hotel was very clean and easily accessible between restaurant, room, and galleries.
Stayed 1 night in Jun 2025