A historic stone fortress with a central dome and surrounding walls.

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Check availability on Colon 5 Star Hotels

Tonight
3 Oct - 4 Oct
Tomorrow
4 Oct - 5 Oct
Next weekend
9 Oct - 11 Oct
In two weeks
16 Oct - 18 Oct

Our top choices for Colon 5-star hotels

A rooftop pool with sun loungers and umbrellas, surrounded by palm trees and modern buildings.
A hotel room with a bed, a TV, a desk, and a view of the cityscape through a window.
A modern hotel room with a dining area, a TV, and a city view.
A spacious lobby with a central seating area, a chandelier, and a modern ceiling design.

1. Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
Bella Vista
United States
Avanel
3.576.889 ₫
3.934.578 ₫ total
includes taxes & fees
25 Oct - 26 Oct
Hotel Riu Plaza Panama
A person seated at a bar with a drink, in a room with a teal accent wall and hanging lights.
A tall, modern building with a prominent logo at the top, surrounded by other high-rise buildings in a cityscape.
An outdoor seating area with wicker chairs and tables, large windows offering a city view at dusk.
A modern building with a rooftop lounge area, large windows, and a balcony overlooking a cityscape.

2. Waldorf Astoria Panama

Waldorf Astoria Panama
Bella Vista
United States
Aysha
6.584.586 ₫
7.243.045 ₫ total
includes taxes & fees
31 Oct - 1 Nov
Waldorf Astoria Panama
A balcony with a table, chairs, and a view of a city skyline across a body of water.
A spacious lobby with a round coffee table, seating areas, and a large wall clock.
A spacious lobby with high ceilings, modern furniture, and decorative lighting fixtures.
A spacious living room with a high ceiling, large windows, and a decorative ceiling fan.

3. Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City
Casco Viejo
United States
Jose
9.121.437 ₫
10.033.581 ₫ total
includes taxes & fees
3 Nov - 4 Nov
Sofitel Legend Casco Viejo, Panama City
A modern hotel room with a sofa, a coffee table, a TV mounted on the wall, and a dining area with a table and chairs.
The exterior of the Renaissance Hotel with a modern design, featuring a prominent 'R' logo, a geometric ceiling design, and a well-lit entrance area.
An indoor swimming pool with lounge chairs and red chairs, surrounded by lush greenery and a modern interior design.
A modern lobby with a staircase, marble flooring, and large windows with tropical plants.

4. Renaissance Panama City Hotel

Renaissance Panama City Hotel
Bella Vista
United States
Carlos
3.300.349 ₫
3.630.384 ₫ total
includes taxes & fees
10 Oct - 11 Oct
Renaissance Panama City Hotel
A poolside area with lounge chairs and a view of the ocean.
A modern building with a symmetrical facade, multiple balconies, and a central atrium with lighting.
A terrace with seating and a view of the ocean.
A modern hotel room with a large bed, a chair, a nightstand with a lamp, and a view of the cityscape at dusk.

5. JW Marriott Panama

JW Marriott Panama
San Francisco
United States
Nemanja
7.047.674 ₫
7.752.442 ₫ total
includes taxes & fees
31 Oct - 1 Nov
JW Marriott Panama
A pool area with lounge chairs and umbrellas, surrounded by greenery and a multi-story building in the background.
A modern interior with a central seating area, potted plants, and a staircase.
A modern building with a sign reading 'HYATT REGENCY.'
A spacious hotel lobby with modern furniture, large windows, and a city view.

6. Hyatt Regency Panama City

Hyatt Regency Panama City
Bella Vista
United States
Mariah
4.859.569 ₫
5.345.526 ₫ total
includes taxes & fees
11 Oct - 12 Oct
Hyatt Regency Panama City
A hotel entrance with a central water feature, seating areas, and potted plants.
A spacious lobby with a wooden ceiling, a central wooden table surrounded by potted plants, and a marble wall with a large window in the background.
An outdoor dining area with wicker chairs and tables, a bar with bottles, and a pool in the background.
A pool with a central water feature, surrounded by seating areas and potted plants.

7. The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Juan Diaz
United States
Shelly-Ann
6.022.487 ₫
6.624.866 ₫ total
includes taxes & fees
31 Oct - 1 Nov
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
A modern restaurant with large windows offering a city view, warm lighting, and contemporary furniture.
A modern living room with a city view, featuring a purple accent wall, a white sofa, and a glass table.
A modern hotel room with a large bed, a desk, a chair, and a view of the cityscape.
A modern high-rise building with a prominent 'W' logo, surrounded by other buildings and a busy street at night.

8. W Panama

W Panama
Bella Vista
United States
Naomi
6.008.194 ₫
6.609.014 ₫ total
includes taxes & fees
1 Nov - 2 Nov
W Panama
A modern hotel pool area with lounge chairs and a clear view of the ocean.
A modern interior with a spiral staircase, a large window, and a seating area.
A spacious lobby with a large seating area, a glass display case with bottles, and a view of the city at night.
A modern bar area with seating and a view of the city.

9. Hilton Panama

Hilton Panama
Bella Vista
United States
Simon
6.584.586 ₫
7.243.045 ₫ total
includes taxes & fees
2 Nov - 3 Nov
Hilton Panama
A hotel with a pool, beach, and palm trees.
A beachfront hotel with a large building, a beach, and a clear sky.
A spacious lobby with a modern design, featuring a central seating area with sofas and ottomans, surrounded by large, open spaces and natural light.
A large hotel with multiple towers, a central courtyard with a swimming pool, and surrounding landscaped areas.

10. The Westin Playa Bonita Panama

The Westin Playa Bonita Panama
Veracruz
United States
Anna
5.353.241 ₫
5.888.565 ₫ total
includes taxes & fees
13 Oct - 14 Oct
The Westin Playa Bonita Panama
A modern living room with a sofa, round black ottomans, and a vase of flowers. A cityscape is visible through the window.
A bar area with a long counter, multiple bar stools, and a television screen. There are large windows providing natural light and a view of the outdoors.
A cozy outdoor seating area with a wooden bench and white tables, surrounded by lush greenery and potted plants.
A rooftop swimming pool with a cityscape view, glass railings, and a modern architectural design.

11. Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel
Bella Vista
United States
Juliet
5.500.149 ₫
6.050.164 ₫ total
includes taxes & fees
4 Oct - 5 Oct
Bristol Panama, a Registry Collection Hotel
Lobby
Banquet hall
Outdoor pool
Breakfast area

12. Waymore Hotel Spa and Casino

Waymore Hotel Spa and Casino
Bella Vista
United States
Aldo
2.720.190 ₫
3.004.757 ₫ total
includes taxes & fees
4 Oct - 5 Oct
Waymore Hotel Spa and Casino
Terrace/patio
Outdoor pool
Outdoor spa tub
Room

13. Megapolis Hotel Panamá

Megapolis Hotel Panamá
San Francisco
United States
MARVIN
5.548.963 ₫
6.129.109 ₫ total
includes taxes & fees
26 Oct - 27 Oct
Megapolis Hotel Panamá
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Colon.
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

Plaza de la Independencia Casco Viejo Panama City Panama
4.939.971 ₫
5.433.968 ₫ total
5 Oct - 6 Oct
includes taxes & fees
9/10 Wonderful! (1,002 reviews)
Central Hotel Panama Casco Viejo
Megapolis Hotel Panamá

Megapolis Hotel Panamá

Avenida Balboa Panama City
4.174.084 ₫
4.591.492 ₫ total
26 Oct - 27 Oct
includes taxes & fees
8.6/10 Excellent! (1,759 reviews)
Megapolis Hotel Panamá
Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Via Espana 111 Panama City Panama
2.805.297 ₫
3.085.827 ₫ total
29 Oct - 30 Oct
includes taxes & fees
7.8/10 Good! (1,000 reviews)
Hotel El Panama by Faranda Grand, a member of Radisson Individuals
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Colon

Explore the colourful Zona Libre free trade zone for duty-free shopping and visit the historic Colon 2000 cruise port. Discover Panama's colonial history at Fort San Lorenzo, located on the Caribbean coast outside the city.

See all hotels in Colon
A coastal archaeological site with ruins and a clear view of the ocean with boats.

Top Colon Hotel Reviews

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

10/10 Excellent
"Si"
Otto 1-night trip
Posted 12 hours ago
Hotel Riu Plaza Panama

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Colon?
How much you pay for a 5-star hotel in Colon can vary depending on the time of year you travel and how long you plan to stay, among a range of factors. Use our price per night filter and other search tools to score the best rate on a high-end stay.
  • Search for the lowest price per night from 3.085.827 ₫
What makes a hotel 5 stars in Colon?
Exceptional guest service is the hallmark of every 5-star hotel in Colon. From the moment you arrive, staff are at your beck and call, whether recommending activities or providing in-room massage treatments. Additionally, hotels have to feature superior conveniences to meet the standard for a 5-star rating. These can include deluxe baths, a wellness centre, swimming pools, gastronomic restaurants and knowledgeable concierge.
Are there any 5-star all-inclusive resorts in Colon?
Find an indulgent stay that includes your room, meals, drinks and entertainment in Colon with the help of Expedia's filter tool. Search for properties rated 5 stars and select the "All inclusive" filter. Have a look at what's included in the upfront price. That way, you can take full advantage of all the perks on offer when you get there.