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Check availability on Colon 5 Star Hotels

Our top choices for Colon 5-star hotels

Outdoor pool, pool loungers
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (4663)
"Awesome great place to stay "
United States
Herbert
The price is 3.371.118 ₫
3.708.230 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Hotel Riu Plaza Panama
2 bars/lounges, poolside bar
Waldorf Astoria Panama

Waldorf Astoria Panama

Waldorf Astoria Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1003)
"I loved everything about my stay "
United States
Stephanie
The price is 5.802.798 ₫
6.383.078 ₫ total
includes taxes & fees
3 Jan - 4 Jan 2026
Waldorf Astoria Panama
2 restaurants, local cuisine
W Panama

W Panama

W Panama
5.0 star property
Bella Vista
9.0 out of 10, Wonderful, (1003)
"It is a hotel with very comfortable and nicely designed rooms in the heart of Panama City. The hotel staff is efficient, attentive and friendly."
United States
SVETLANA
The price is 5.661.266 ₫
6.227.393 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
W Panama
4 outdoor pools, free pool cabanas, pool umbrellas
JW Marriott Panama

JW Marriott Panama

JW Marriott Panama
5.0 star property
San Francisco
9.0 out of 10, Wonderful, (1006)
"Bedroom was very comfy, also the staff were very on point. I will definitely recommend this hotel and there services, there is so much to do at this hotel."
United States
Sarran
The price is 6.605.688 ₫
7.266.257 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
JW Marriott Panama
Room, 1 King Bed, Balcony, Oceanfront (Magnifique) | Premium bedding, down duvets, pillow-top beds, minibar
Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City
5.0 star property
Casco Viejo
9.8 out of 10, Exceptional, (557)
"Great hotel and location "
United Kingdom
Russell
The price is 10.062.428 ₫
11.068.671 ₫ total
includes taxes & fees
12 Jan - 13 Jan 2026
Sofitel Legend Casco Viejo, Panama City
Sports facility
Hilton Panama

Hilton Panama

Hilton Panama
5.0 star property
Bella Vista
8.8 out of 10, Excellent, (1001)
"It was excellent as a whole, but I requested ocean view room but got a city view and I was supposed to breakfast free but it was not free and paid us$56 plus tax 7% every day for breakfast. I need a credit for breakfasts payments. I.e. $359.52 US"
Canada
Majid
The price is 4.897.048 ₫
5.386.753 ₫ total
includes taxes & fees
2 Jan - 3 Jan 2026
Hilton Panama
3 outdoor pools, pool umbrellas, pool loungers
The Westin Playa Bonita Panama

The Westin Playa Bonita Panama

The Westin Playa Bonita Panama
5.0 star property
Veracruz
8.0 out of 10, Very good, (1002)
"Our stay was very nice, the service the hotel provides is wonderful, I highly recommend it"
United States
Mayra Alexandra Montes
The price is 5.235.093 ₫
5.758.602 ₫ total
includes taxes & fees
15 Dec - 16 Dec
The Westin Playa Bonita Panama
40-inch Smart TV with cable channels, TV
Renaissance Panama City Hotel

Renaissance Panama City Hotel

Renaissance Panama City Hotel
5.0 star property
Bella Vista
8.8 out of 10, Excellent, (95)
"Great location and amazing staff"
United States
Aziz
The price is 3.051.612 ₫
3.356.773 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Renaissance Panama City Hotel
Couples treatment room(s), sauna, steam room, body treatments
Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel
5.0 star property
Bella Vista
9.4 out of 10, Exceptional, (1005)
"Love this hotel. Busy area, but hotel and restaurant make up for it."
United States
Allen
The price is 5.791.486 ₫
6.370.766 ₫ total
includes taxes & fees
20 Dec - 21 Dec
Bristol Panama, a Registry Collection Hotel
View from property
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
Juan Diaz
9.6 out of 10, Exceptional, (638)
"As usual the stay was amazing in this hotel"
United States
Jose
The price is 6.096.647 ₫
6.706.312 ₫ total
includes taxes & fees
19 Dec - 20 Dec
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
View from property
Megapolis Hotel Panamá

Megapolis Hotel Panamá

Megapolis Hotel Panamá
5.0 star property
San Francisco
8.4 out of 10, Very good, (1000)
"Great stay! Very safe!"
United States
MARVIN
Megapolis Hotel Panamá
Lobby
Waymore Hotel Spa and Casino

Waymore Hotel Spa and Casino

Waymore Hotel Spa and Casino
5.0 star property
Bella Vista
6.2 out of 10, (1000)
"It has a nice casino and it's very conveniently located. Breakfast was very good as well. Staff very helpful and attention oriented. Good experience "
United States
Aldo
Waymore Hotel Spa and Casino
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Colon.
Megapolis Hotel Panamá

Megapolis Hotel Panamá

Avenida Balboa Panama City
The price is 3.448.235 ₫ per night from 15 Dec to 16 Dec
3.448.235 ₫
3.793.059 ₫ total
15 Dec - 16 Dec
includes taxes & fees
8.4/10 Very Good! (1,267 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Colon

Explore the colourful Zona Libre free trade zone for duty-free shopping and visit the historic Colon 2000 cruise port. Discover Panama's colonial history at Fort San Lorenzo, located on the Caribbean coast outside the city.

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Top Colon Hotel Reviews

Frequently asked questions

How much does it cost to stay in a 5-star hotel in Colon?
How much you pay for a 5-star hotel in Colon can vary depending on the time of year you travel and how long you plan to stay, among a range of factors. Use our price per night filter and other search tools to score the best rate on a high-end stay.

  • Search for the lowest price per night from 3.793.059 ₫

What makes a hotel 5 stars in Colon?
Exceptional guest service is the hallmark of every 5-star hotel in Colon. From the moment you arrive, staff are at your beck and call, whether recommending activities or providing in-room massage treatments. Additionally, hotels have to feature superior conveniences to meet the standard for a 5-star rating. These can include deluxe baths, a wellness centre, swimming pools, gastronomic restaurants and knowledgeable concierge.
Are there any 5-star all-inclusive resorts in Colon?
Find an indulgent stay that includes your room, meals, drinks and entertainment in Colon with the help of Expedia's filter tool. Search for properties rated 5 stars and select the "All inclusive" filter. Have a look at what's included in the upfront price. That way, you can take full advantage of all the perks on offer when you get there.

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