A coastal landscape with rocky cliffs, green hills, and a clear blue sea.

Compare and book 5 Star hotels in Mediterranean Region,

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check availability on Mediterranean Region 5 Star Hotels

This weekend
Next weekend

Our top choices for Mediterranean Region 5-star hotels

Grand Hyatt Athens

Grand Hyatt Athens
5.0 star property
Neos Kosmos
8.6 out of 10, Excellent, (1,288 reviews)
"Hotel was super nice, booked a big spacious room for 3 people. Hotel staff was amazing and very helpful. Very empathetic with guests needs."
United States
Juan
The price is 4.733.467 ₫
5.838.011 ₫ total
includes taxes & fees
2 Jul - 3 Jul
Grand Hyatt Athens

Sofitel Athens Airport

Sofitel Athens Airport
5.0 star property
Spata-Artemida
9.4 out of 10, Exceptional, (2,623 reviews)
"Very good airport hotel ."
United States
Thomas
The price is 11.863.106 ₫
13.921.414 ₫ total
includes taxes & fees
6 Jul - 7 Jul
Sofitel Athens Airport

Lamaro Hotel Barcelona 5★ | Preferred Hotels & Resorts | Lifestyle Collection

Lamaro Hotel Barcelona 5★ | Preferred Hotels & Resorts | Lifestyle Collection
5.0 star property
Downtown Barcelona
9.4 out of 10, Exceptional, (1,844 reviews)
"Amazing hotel, felt special, great location & lovely friendly staff too."
United Kingdom
Nisha
The price is 7.727.613 ₫
9.290.752 ₫ total
includes taxes & fees
1 Jul - 2 Jul
Lamaro Hotel Barcelona 5★ | Preferred Hotels & Resorts | Lifestyle Collection

Corinthia Lisbon

Corinthia Lisbon
5.0 star property
Lisbon City Center
9.6 out of 10, Exceptional, (1,265 reviews)
"Friendly and clean hotel"
Canada
Tara
The price is 6.411.335 ₫
7.035.553 ₫ total
includes taxes & fees
30 Jun - 1 Jul
Corinthia Lisbon

Hotel Arts Barcelona

Hotel Arts Barcelona
5.0 star property
Barceloneta
9.0 out of 10, Wonderful, (1,001 reviews)
"Everything was fantastic, from our very pleasant check in to the end of our stay was great and out of expectation Thank you Hotel Art Barcelona!!"
Canada
Sepehr
The price is 14.954.293 ₫
17.240.099 ₫ total
includes taxes & fees
24 Jul - 25 Jul
Hotel Arts Barcelona

Grand Hyatt Barcelona

Grand Hyatt Barcelona
5.0 star property
Les Corts
9.2 out of 10, Wonderful, (1,566 reviews)
"Great place to stay. "
United States
Le
The price is 7.321.330 ₫
8.843.840 ₫ total
includes taxes & fees
4 Jul - 5 Jul
Grand Hyatt Barcelona

InterContinental Barcelona by IHG

InterContinental Barcelona by IHG
5.0 star property
El Poble-sec
9.2 out of 10, Wonderful, (1,000 reviews)
"Excellent stay !"
United Kingdom
NICHOLAS
The price is 6.172.779 ₫
7.580.434 ₫ total
includes taxes & fees
30 Jun - 1 Jul
InterContinental Barcelona by IHG

EPIC SANA Marques Hotel

EPIC SANA Marques Hotel
5.0 star property
Lisbon City Center
9.6 out of 10, Exceptional, (1,401 reviews)
"Had a great stay"
United States
Benjamin
The price is 6.543.963 ₫
7.176.264 ₫ total
includes taxes & fees
3 Jul - 4 Jul
EPIC SANA Marques Hotel

Hyatt Regency Barcelona Tower

Hyatt Regency Barcelona Tower
5.0 star property
Bellvitge
9.0 out of 10, Wonderful, (1,154 reviews)
"Very nice location and excellent hospitality"
Canada
Karim
The price is 4.395.520 ₫
5.131.463 ₫ total
includes taxes & fees
20 Jul - 21 Jul
Hyatt Regency Barcelona Tower

EPIC SANA Lisboa Hotel

EPIC SANA Lisboa Hotel
5.0 star property
Lisbon City Center
9.6 out of 10, Exceptional, (1,046 reviews)
"Great place to stay at"
United States
Lotfi
The price is 9.122.777 ₫
9.909.651 ₫ total
includes taxes & fees
5 Jul - 6 Jul
EPIC SANA Lisboa Hotel

Divani Palace Acropolis

Divani Palace Acropolis
5.0 star property
Athens City Centre
9.0 out of 10, Wonderful, (1,005 reviews)
"The place and the staff were awesome"
United States
Richard
The price is 6.179.805 ₫
7.484.632 ₫ total
includes taxes & fees
13 Jul - 14 Jul
Divani Palace Acropolis

Athenaeum InterContinental by IHG

Athenaeum InterContinental by IHG
5.0 star property
Neos Kosmos
9.0 out of 10, Wonderful, (1,000 reviews)
"Everything was great. Staff, cleanliness, breakfast and we also tried the spa was excellent"
United States
Antonio
The price is 5.894.297 ₫
7.159.499 ₫ total
includes taxes & fees
23 Jul - 24 Jul
Athenaeum InterContinental by IHG

Swandor Hotels & Resort Topkapi Palace - All Inclusive

Swandor Hotels & Resort Topkapi Palace - All Inclusive
5.0 star property
Lara
9.0 out of 10, Wonderful, (2,102 reviews)
"We loved our stay. Very nice place to relax."
United States
Blerina
The price is 6.478.626 ₫
7.191.275 ₫ total
includes taxes & fees
26 Jul - 27 Jul
Swandor Hotels & Resort Topkapi Palace - All Inclusive

W Barcelona

W Barcelona
5.0 star property
Barceloneta
8.8 out of 10, Excellent, (1,003 reviews)
"Excellent stay"
United States
Sos
The price is 11.616.148 ₫
13.568.140 ₫ total
includes taxes & fees
28 Jul - 29 Jul
W Barcelona

Concorde De Luxe Resort Lara Antalya - Prive Ultra All Inclusive

Concorde De Luxe Resort Lara Antalya - Prive Ultra All Inclusive
5.0 star property
Lara
9.6 out of 10, Exceptional, (1,102 reviews)
"Friendly & helpful staff, easy access around the resort."
United Kingdom
Bablu
The price is 10.529.015 ₫
11.687.206 ₫ total
includes taxes & fees
30 Jun - 1 Jul
Concorde De Luxe Resort Lara Antalya - Prive Ultra All Inclusive

Barceló Torre de Madrid

Barceló Torre de Madrid
5.0 star property
Madrid Centro
9.4 out of 10, Exceptional, (2,604 reviews)
"Great location, wonderful breakfast"
United States
Wendell
The price is 5.609.282 ₫
6.170.330 ₫ total
includes taxes & fees
29 Jul - 30 Jul
Barceló Torre de Madrid

Nobu Hotel Barcelona

Nobu Hotel Barcelona
5.0 star property
Sants-Montjuïc
9.0 out of 10, Wonderful, (1,316 reviews)
"Nice room, good location"
United States
tom
The price is 7.375.764 ₫
8.903.718 ₫ total
includes taxes & fees
29 Jul - 30 Jul
Nobu Hotel Barcelona

Electra Metropolis Athens

Electra Metropolis Athens
5.0 star property
Athens City Centre
9.6 out of 10, Exceptional, (1,186 reviews)
"Great hotel in a good location."
United States
Patricia
The price is 10.755.415 ₫
12.693.635 ₫ total
includes taxes & fees
7 Jul - 8 Jul
Electra Metropolis Athens

Zeus Dolce by Wyndham Athens

Zeus Dolce by Wyndham Athens
5.0 star property
Markopoulo Mesogaias
7.4 out of 10, Good, (383 reviews)
"Great stay!!"
United States
Aundre
The price is 5.089.272 ₫
6.228.710 ₫ total
includes taxes & fees
1 Jul - 2 Jul
Zeus Dolce by Wyndham Athens

Eurostars Grand Marina

Eurostars Grand Marina
5.0 star property
Downtown Barcelona
9.0 out of 10, Wonderful, (1,313 reviews)
"Great breakfast and very friendly staff"
United States
Jeremy
The price is 5.171.281 ₫
6.478.786 ₫ total
includes taxes & fees
12 Jul - 13 Jul
Eurostars Grand Marina
Save an average of 15% on thousands of hotels when you're signed in

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Mediterranean Region.
Still don't see what you're looking for?
See all properties in Mediterranean Region.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Mediterranean Region

Plan your trip to Mediterranean Region and take advantage of the sights and activities in the area.

A winding road through a mountainous landscape with the sun setting behind the hills.

Top Mediterranean Region Hotel Reviews