Compare and book 5 Star hotels in Mendrisio, Canton of Ticino

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Check availability on Mendrisio 5 Star Hotels

Tonight
6 Dec - 7 Dec
Tomorrow
7 Dec - 8 Dec
Next weekend
12 Dec - 14 Dec
In two weeks
19 Dec - 21 Dec

Top Mendrisio 5 Star Hotels

Turkish bath/hammam, body treatments, body wraps, body scrubs, facials
Grand Hotel Tremezzo

Grand Hotel Tremezzo

5.0 star property
Tremezzina
9.8 out of 10, Exceptional, (87)
"Nicest hotel I’ve ever stayed in - unbelievable experience all around."
United States
Jordan
Grand Hotel Tremezzo
Hallway
Hotel Splendide Royal

Hotel Splendide Royal

5.0 star property
Loreto
9.4 out of 10, Exceptional, (458)
"Great place to stay "
United States
carla
The price is 7.952.617 ₫
8.559.459 ₫ total
includes taxes & fees
7 Dec - 8 Dec
Hotel Splendide Royal
Indoor pool, outdoor pool, pool umbrellas, pool loungers
Grand Hotel Villa Serbelloni

Grand Hotel Villa Serbelloni

5.0 star property
Historic Center
9.2 out of 10, Wonderful, (550)
"The staff were wonderful and the hotel was impeccable. All amenities were extremely thoughtful."
United States
Brian
Grand Hotel Villa Serbelloni
Mandarin, Suite | Premium bedding, down duvets, minibar, in-room safe
Mandarin Oriental, Lago di Como

Mandarin Oriental, Lago di Como

5.0 star property
Blevio
9.4 out of 10, Exceptional, (482)
"The staff was amazing "
United States
Maria
Mandarin Oriental, Lago di Como
Exterior
Grand Hotel Villa Castagnola

Grand Hotel Villa Castagnola

5.0 star property
Cassarate
9.6 out of 10, Exceptional, (393)
"Amazing hotel and a truly special place."
United Kingdom
steve
The price is 14.516.681 ₫
15.372.957 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Grand Hotel Villa Castagnola
View from room
Grand Hotel Campione

Grand Hotel Campione

5.0 star property
Campione d'Italia
9.0 out of 10, Wonderful, (166)
"Very good breakfast and welcoming atmosphere "
United Kingdom
Ehab
Grand Hotel Campione
Front of property
Villa Principe Leopoldo

Villa Principe Leopoldo

5.0 star property
Loreto
9.2 out of 10, Wonderful, (341)
"Awesome hotel with friendly staff, a beautiful and spacious room, an incredible location and great common rooms overlooking Lake Lugano. Would highly recommend to others. "
United States
J Theodore
Villa Principe Leopoldo
Junior Suite, Terrace, Lake View | In-room safe, free WiFi
Swiss Diamond Boutique Hotel La Romantica

Swiss Diamond Boutique Hotel La Romantica

5.0 star property
Melide
9.8 out of 10, Exceptional, (17)
"Beautiful location and friendly staffs are impressive. Would love to visit again. "
United States
Susan
The price is 10.480.413 ₫
11.183.311 ₫ total
includes taxes & fees
7 Dec - 8 Dec
Swiss Diamond Boutique Hotel La Romantica
Beach
Grand Hotel Victoria Concept & Spa, by R Collection Hotels

Grand Hotel Victoria Concept & Spa, by R Collection Hotels

5.0 star property
Menaggio
9.8 out of 10, Exceptional, (95)
"Beautiful property with excellent service."
United States
Gabriel
Grand Hotel Victoria Concept & Spa, by R Collection Hotels
Terrace/patio
Swiss Diamond Hotel & SPA

Swiss Diamond Hotel & SPA

5.0 star property
Vico Morcote
9.0 out of 10, Wonderful, (435)
"Beautiful property, very friendly and helpful staff. The breakfast buffet was excellent! We had a wonderful time."
Canada
Sabrina
Swiss Diamond Hotel & SPA
Breakfast area
ARIA Retreat & SPA - The Leading Hotels of the World, located within Parco San Marco Resort

ARIA Retreat & SPA - The Leading Hotels of the World, located within Parco San Marco Resort

5.0 star property
Porlezza
9.8 out of 10, Exceptional, (78)
"This was the nicest hotel that we have ever stayed at, and the food was out of this world."
United States
Jeremy
The price is 24.621.271 ₫
27.083.398 ₫ total
includes taxes & fees
2 Jan - 3 Jan 2026
ARIA Retreat & SPA - The Leading Hotels of the World, located within Parco San Marco Resort
Junior Suite, 1 King Bed, Lake View, Corner | Minibar, in-room safe, desk, soundproofing
Palazzo Venezia

Palazzo Venezia

5.0 star property
Como City Centre
9.8 out of 10, Exceptional, (119)
"The hotel was in a perfect location. Next to the lake. Nice rooftop bar and dinner at the hotel restaurant was absolutely delicious. Super friendly staff. Easy access to ferries. Would definitely stay here again. "
United States
Susana
Palazzo Venezia
Outdoor dining
Passalacqua

Passalacqua

5.0 star property
Moltrasio
10.0 out of 10, Exceptional, (18)
"Entire hotel is a 12/10 but add in that they have ALL the Dyson products in each room!!! "
United States
bernard
Passalacqua
Restaurant
Bianca Relais - by R Collection Hotels

Bianca Relais - by R Collection Hotels

5.0 star property
Oggiono
9.8 out of 10, Exceptional, (50)
"simple n modern design beautiful lakeview"
Hong Kong SAR China
Po Mei
The price is 12.940.125 ₫
14.234.137 ₫ total
includes taxes & fees
19 Dec - 20 Dec
Bianca Relais - by R Collection Hotels
Indoor pool
The View Lugano

The View Lugano

5.0 star property
Paradiso
9.6 out of 10, Exceptional, (157)
"Wonderful hotel, can’t praise it enough. Look forward to our next stay! "
United States
Jonathan
The price is 17.838.161 ₫
18.820.653 ₫ total
includes taxes & fees
9 Dec - 10 Dec
The View Lugano
SOLE LUXURY ROOM WITH SPECTACULAR VIEW | Egyptian cotton sheets, premium bedding, down duvets, memory-foam beds
Nuvole Garden Hotel

Nuvole Garden Hotel

5.0 star property
Brunate
8.4 out of 10, Very good, (8)
"Excellent service and environment. Such a resort on top of lake Como with full view. Highly recommended. "
Hong Kong SAR China
Tsun
The price is 13.185.535 ₫
14.811.028 ₫ total
includes taxes & fees
9 Dec - 10 Dec
Nuvole Garden Hotel
Private beach, waterskiing, kayaking, motor boating
Hotel Eden Roc

Hotel Eden Roc

5.0 star property
Ascona
9.4 out of 10, Exceptional, (129)
"Super Hotel! "
Germany
Stephan
Hotel Eden Roc
Junior Suite, Lake View, Annex Building (in grotta) | Lake view
Villa Lario Resort Mandello

Villa Lario Resort Mandello

5.0 star property
Mandello del Lario
9.8 out of 10, Exceptional, (38)
"Great well run resort"
United States
gordon
Villa Lario Resort Mandello
Indoor pool, seasonal outdoor pool, pool umbrellas, pool loungers
Resort Collina d'Oro

Resort Collina d'Oro

5.0 star property
Collina d'Oro
9.2 out of 10, Wonderful, (163)
"Excellent resort"
United States
Gregory
Resort Collina d'Oro
Exterior
Giardino Ascona

Giardino Ascona

5.0 star property
Ascona
9.6 out of 10, Exceptional, (75)
"We loved being there and being taken care of by amazing staff."
United States
Karin
Giardino Ascona
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Mendrisio.
First Hotel Malpensa

First Hotel Malpensa

Via Baracca 34 Somma Lombardo VA
The price is 2.511.320 ₫ per night from 10 Dec to 11 Dec
2.511.320 ₫
2.885.228 ₫ total
10 Dec - 11 Dec
includes taxes & fees
8.6/10 Excellent! (1,019 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Mendrisio

Tucked between Lake Lugano and Generoso Mount, this charming town invites you to explore its cultural treasures at Museum d'Art and Galleria Baumgartner. Bargain hunters flock to FoxTown Factory Stores while nature lovers can discover the UNESCO-listed Monte San Giorgio with its remarkable fossil deposits.

See all hotels in Mendrisio
Panoramic aerial view of a Swiss city. Mendrisio with to the right the church of Saints Cosmas and Damian, Switzerland

Top Mendrisio Hotel Reviews

Grand Hotel Villa Serbelloni

Grand Hotel Villa Serbelloni

10/10 Excellent
"The staff were wonderful and the hotel was impeccable. All amenities were extremely thoughtful."
Brian 1-night trip
Posted 1 month ago
Grand Hotel Villa Serbelloni

Frequently asked questions

What are the best 5-star hotels in Mendrisio?
Get ready for 5-star luxuriousness at Swiss Diamond Hotel & SPA, Resort Collina d'Oro or The View Lugano. These are some of the leading properties in Mendrisio according to Expedia traveller reviews. Book your favourite and get a taste of the finer life!
How much does it cost to stay in a 5-star hotel in Mendrisio?
The amount you pay for a 5-star hotel in Mendrisio can vary depending on when you prefer to travel and how long you plan to be away, among several factors. Use our price per night filter and other search tools to score the best deal on a high-end stay.

  • Search for the lowest price per night from 2.247.531 ₫

What makes a hotel 5 stars in Mendrisio?
Impeccable guest service is at the heart of every 5-star hotel in Mendrisio. From the instant you arrive, staff cater to your every whim, whether recommending activities and tours or providing in-room massages. Additionally, hotels have to offer top-rate conveniences to obtain a 5-star rating. These can include luxury bathrobes, spas or saunas, swimming pools, gourmet kitchens and knowledgeable concierge.

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