Compare and book 5 Star hotels in Mytilene, Lesvos
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check availability on Mytilene 5 Star Hotels
Tonight
28 Aug - 29 AugTomorrow
29 Aug - 30 AugThis weekend
28 Aug - 30 AugNext weekend
4 Sep - 6 SepOur top choices for Mytilene 5-star hotels
3.650.317 ₫
4.454.682 ₫ total
includes taxes & fees
2 Sept - 3 Sept
4.126.528 ₫
5.736.254 ₫ total
includes taxes & fees
26 Sept - 27 Sept
Save an average of 15% on thousands of hotels when you're signed in
Explore similar 4-star hotels
Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Mytilene.
Loriet Hotel
Vareia, Mitilene Lesvos Lesvos Island
3.679.346 ₫
4.334.502 ₫ total
17 Sept - 18 Sept
includes taxes & fees
8.4/10 Very good! (91 reviews)
Heliotrope Hotels
Varia Lesvos Lesvos Island
3.820.859 ₫
4.489.522 ₫ total
30 Aug - 31 Aug
includes taxes & fees
Theofilos Paradise Boutique Hotel
7, Skra str, Hatzidimitriou Park Lesvos
4.204.406 ₫
4.909.598 ₫ total
20 Sept - 21 Sept
includes taxes & fees
9.6/10 Exceptional! (171 reviews)
Still don't see what you're looking for?
See all properties in Mytilene.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Learn more about Mytilene
The harbour city's neoclassical mansions and Byzantine castle offer glimpses into its rich past as a trading centre. Explore the Archaeological Museum's ancient artefacts, then enjoy fresh seafood at tavernas along the waterfront promenade.
See all hotels in Mytilene
Top Mytilene Hotel Reviews
Frequently asked questions
How much does it cost to stay in a 5-star hotel in Mytilene?
How much you pay for a 5-star hotel in Mytilene depends on factors such as when you plan to travel and the length of your trip. A top tip for scoring the best deal? Use our pricing filters to check out the available options for your preferred dates.
- Search for the lowest price per night from 4.334.502 ₫
What makes a hotel 5 stars in Mytilene?
From fine dining venues and 24-hour fitness centres to pools and dreamy bedding, the 5-star experience in Mytilene is all about luxury and comfort. But it takes more than just top-notch perks to earn a 5-star rating. Accommodation must also deliver superb guest services like in-room massage treatments, dry cleaning and laundry and a nightly turn-down service.
Are there any 5-star all-inclusive resorts in Mytilene?
Find an indulgent getaway that includes your lodging, food, activities and entertainment in Mytilene with our filter tool. Search for properties rated 5 stars and select the "All inclusive" filter. Be sure to check what's included in the price. That way, you can take full advantage of all the perks on offer when you arrive.