Compare and book 5 Star hotels in Rhine Valley, Europe

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check availability on Rhine Valley 5 Star Hotels

This weekend
Next weekend

Our top choices for Rhine Valley 5-star hotels

Maison Rouge Strasbourg Hotel&Spa, Autograph Collection

Maison Rouge Strasbourg Hotel&Spa, Autograph Collection
5.0 star property
City-Centre - Petite France
9.4 out of 10, Exceptional, (480 reviews)
"Great location, very kind staff , nice breakfast and clean room"
United States
Ahmed
The price is 5.680.152 ₫
6.484.940 ₫ total
includes taxes & fees
12 Jul - 13 Jul
Maison Rouge Strasbourg Hotel&Spa, Autograph Collection

Steigenberger Icon Parkhotel Düsseldorf

Steigenberger Icon Parkhotel Düsseldorf
5.0 star property
Stadtmitte
9.0 out of 10, Wonderful, (784 reviews)
"Good location, nice hotel"
Canada
shawn
The price is 6.398.204 ₫
7.025.451 ₫ total
includes taxes & fees
12 Jul - 13 Jul
Steigenberger Icon Parkhotel Düsseldorf

Excelsior Hotel Ernst am Dom

Excelsior Hotel Ernst am Dom
5.0 star property
Old Town Cologne
9.6 out of 10, Exceptional, (1,000 reviews)
"Extremely friendly staffs~ great location!"
Singapore
Malcolm
The price is 7.518.588 ₫
8.447.283 ₫ total
includes taxes & fees
21 Jul - 22 Jul
Excelsior Hotel Ernst am Dom

Breidenbacher Hof

Breidenbacher Hof
5.0 star property
Stadtmitte
9.6 out of 10, Exceptional, (549 reviews)
"Just excellent service attention to detail and helpful friendly team can see why it is hotel of 2026!"
United Kingdom
Andrew Geoffrey
The price is 13.550.750 ₫
14.678.708 ₫ total
includes taxes & fees
26 Jun - 27 Jun
Breidenbacher Hof

Hôtel & Spa RÉGENT PETITE FRANCE By Stay Collection

Hôtel & Spa RÉGENT PETITE FRANCE By Stay Collection
5.0 star property
City-Centre - Petite France
9.4 out of 10, Exceptional, (1,004 reviews)
"We enjoyed our stay. Highly recommended"
United States
BARIS
The price is 4.781.927 ₫
5.496.893 ₫ total
includes taxes & fees
5 Jul - 6 Jul
Hôtel & Spa RÉGENT PETITE FRANCE By Stay Collection

Sofitel Strasbourg Grande Ile

Sofitel Strasbourg Grande Ile
5.0 star property
City-Centre - Petite France
8.6 out of 10, Excellent, (857 reviews)
"The staff was exceptionally friendly and helpful. We highly recommend the breakfast. Great service and variety of food options. The room was a bit on the small side but it had everything we needed."
United States
Joy
The price is 5.136.597 ₫
5.887.030 ₫ total
includes taxes & fees
11 Jul - 12 Jul
Sofitel Strasbourg Grande Ile

Brenners Park - Hotel & Spa, Oetker Hotels

Brenners Park - Hotel & Spa, Oetker Hotels
5.0 star property
Baden-Baden
9.8 out of 10, Exceptional, (134 reviews)
"Best hotel"
United States
Francisco José
The price is 21.373.815 ₫
23.139.147 ₫ total
includes taxes & fees
30 Jun - 1 Jul
Brenners Park - Hotel & Spa, Oetker Hotels

Maison Messmer - ein Mitglied der Hommage Luxury Hotels Collection

Maison Messmer - ein Mitglied der Hommage Luxury Hotels Collection
5.0 star property
Baden-Baden
9.2 out of 10, Wonderful, (845 reviews)
"I will definitely come back everyone and everything was great"
United States
manushak
The price is 6.135.570 ₫
6.834.120 ₫ total
includes taxes & fees
21 Jul - 22 Jul
Maison Messmer - ein Mitglied der Hommage Luxury Hotels Collection

City Hotel Haarhuis - World Hotels Crafted Collections

City Hotel Haarhuis - World Hotels Crafted Collections
5.0 star property
Stationsplein
8.4 out of 10, Very good, (846 reviews)
"Great amenities (sauna, hot tub) and great location. Parking is hard to come by (hotel has a very small lot) but parking at centraal station across the street was near by."
Canada
Nicolette
The price is 2.233.496 ₫
2.917.207 ₫ total
includes taxes & fees
28 Jun - 29 Jun
City Hotel Haarhuis - World Hotels Crafted Collections

L'Esquisse Hotel & Spa Colmar - MGallery Collection

L'Esquisse Hotel & Spa Colmar - MGallery Collection
5.0 star property
Colmar Centre Ville
9.6 out of 10, Exceptional, (249 reviews)
"Wonderful stay and a great location. "
United States
William
The price is 6.457.436 ₫
7.333.376 ₫ total
includes taxes & fees
5 Jul - 6 Jul
L'Esquisse Hotel & Spa Colmar - MGallery Collection

Hotel Europäischer Hof Heidelberg

Hotel Europäischer Hof Heidelberg
5.0 star property
Heidelberg City Centre
9.6 out of 10, Exceptional, (381 reviews)
"It is a beautiful historic hotel. Staff are very friendly."
United States
Qing
The price is 9.443.701 ₫
10.313.960 ₫ total
includes taxes & fees
28 Jun - 29 Jun
Hotel Europäischer Hof Heidelberg

Pavillon REGENT PETITE France By Stay Collection

Pavillon REGENT PETITE France By Stay Collection
5.0 star property
City-Centre - Petite France
9.4 out of 10, Exceptional, (398 reviews)
"It was the best hotel in town. Service, amazing, the room, amazing. the Location, amazing.. so glad we stayed here.."
United States
Katrina
The price is 4.479.726 ₫
5.164.982 ₫ total
includes taxes & fees
5 Jul - 6 Jul
Pavillon REGENT PETITE France By Stay Collection

Grand Hotel Les Trois Rois

Grand Hotel Les Trois Rois
5.0 star property
Basel City Centre
9.4 out of 10, Exceptional, (190 reviews)
"Great food, drinks, decor and staff. "
United States
Adam
The price is 19.833.930 ₫
20.859.996 ₫ total
includes taxes & fees
1 Jul - 2 Jul
Grand Hotel Les Trois Rois

La Maison des Têtes

La Maison des Têtes
5.0 star property
Colmar Centre Ville
9.4 out of 10, Exceptional, (261 reviews)
"Great location and amazing staff. "
United States
Juan
The price is 6.530.816 ₫
7.414.094 ₫ total
includes taxes & fees
29 Jun - 30 Jun
La Maison des Têtes

RIVA - Das Hotel am Bodensee

RIVA - Das Hotel am Bodensee
5.0 star property
Konstanz
10.0 out of 10, Exceptional, (16 reviews)
"The hotel is more than wonderful, and the service is top-notch, transporting us to an atmosphere beyond description."
United States
Naser
The price is 11.365.892 ₫
12.797.980 ₫ total
includes taxes & fees
30 Jun - 1 Jul
RIVA - Das Hotel am Bodensee

Colombi Hotel

Colombi Hotel
5.0 star property
Freiburg im Breisgau
9.4 out of 10, Exceptional, (70 reviews)
"Wonderful hotel with Michelin star restaurant on site. Only 4 star for cleanliness because smoking is allowed in the bar area."
United States
Jeff
Colombi Hotel

Villa La Florangerie Hotel & Spa

Villa La Florangerie Hotel & Spa
5.0 star property
Orangerie
9.2 out of 10, Wonderful, (141 reviews)
"Rude director "
United Kingdom
Mustapha
Villa La Florangerie Hotel & Spa
Save an average of 15% on thousands of hotels when you're signed in

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Rhine Valley.
Still don't see what you're looking for?
See all properties in Rhine Valley.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Rhine Valley

Interesting history, wineries and top sights from Europa-Park to Strasbourg Christmas Market—discover it all in Rhine Valley.

Top Rhine Valley Hotel Reviews

Frequently asked questions

What are the best 5-star hotels in Rhine Valley?
Le Méridien Frankfurt is a top pick for Expedia guests. Roomers, Frankfurt, a Member of Design Hotels and Steigenberger Icon Frankfurter Hof also get rave reviews from our travellers. All located in Frankfurt, Rhine Valley, these 5-star hotels will treat you to the luxury experience from the instant you walk into the lobby.
How much does it cost to stay in a 5-star hotel in Rhine Valley?
You can find a variety of pricing options for 5-star hotels in Rhine Valley on Expedia. How much you'll pay will depend on your travel dates, length of your trip and other factors. Compare available properties for your chosen dates and make use of our pricing and other filters to find the ideal high-end stay.

  • Search for the lowest price per night from 2.856.519 ₫

What makes a hotel 5 stars in Rhine Valley?
Faultless guest service is the hallmark of every 5-star hotel in Rhine Valley. From the instant you arrive, staff cater to your every need, whether arranging valet parking or providing in-room massage treatments. What's more, hotels have to offer superior conveniences to qualify for a 5-star rating. These can include deluxe baths, saunas or spas, swimming pools, gourmet kitchens and knowledgeable concierge.