A beach with waves, a boat, and a forested hill in the background.

Compare and book 5 Star hotels in Santa Clara, Panamá Oeste Province

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Check availability on Santa Clara 5 Star Hotels

Tonight
23 Sep - 24 Sep
Tomorrow
24 Sep - 25 Sep
This weekend
25 Sep - 27 Sep
Next weekend
2 Oct - 4 Oct

Our top choices for Santa Clara 5-star hotels

A rooftop pool with sun loungers and umbrellas, surrounded by palm trees and modern buildings.
A spacious lobby with a central seating area, a chandelier, and a modern ceiling design.
A hotel room with a bed, a TV, a desk, and a view of the cityscape through a window.
A modern living room with a sofa set, a coffee table, and a dining area with chairs and a table.

1. Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
Bella Vista
United States
Sandrelly
3.580.743 ₫
3.938.817 ₫ total
includes taxes & fees
28 Sept - 29 Sept
Hotel Riu Plaza Panama
A resort with a large swimming pool, thatched-roof structures, and palm trees.
An outdoor dining area with tables and chairs, overlooking a body of water and a forested island.
A resort with a pool, palm trees, and a building with a red roof.
A well-maintained garden with a pathway leading to a gazebo, surrounded by palm trees and a view of the sea.

2. Dreams Playa Bonita Panama - All Inclusive

Dreams Playa Bonita Panama - All Inclusive
Veracruz
United States
Joanna
7.239.975 ₫
7.239.975 ₫ total
includes taxes & fees
2 Oct - 3 Oct
Dreams Playa Bonita Panama - All Inclusive
A high-rise building with a modern architectural design, featuring a grid of windows and balconies.
A rooftop lounge with modern seating and a panoramic city view.
An escalator in a hotel lobby with a patterned wall and framed artwork.
A rooftop pool area with purple lounge chairs and a city skyline in the background.

3. Megapolis Hotel Panamá

Megapolis Hotel Panamá
San Francisco
United States
Devika
4.179.383 ₫
4.597.321 ₫ total
includes taxes & fees
24 Sept - 25 Sept
Megapolis Hotel Panamá
A modern hotel with a prominent entrance, multiple floors, and a well-lit facade.
A spacious lobby with a pool table, comfortable seating areas, and a bar with a variety of beverages.
A modern lounge area with seating, a bar, and a staircase.
A modern rooftop pool with a view of high-rise buildings at night.

4. Aloft by Marriott Panama

Aloft by Marriott Panama
San Francisco
United States
Shaniyah
3.441.785 ₫
3.785.964 ₫ total
includes taxes & fees
9 Oct - 10 Oct
Aloft by Marriott Panama
A balcony with wicker chairs and a view of the cityscape.
A hotel room with a large bed, a desk with a lamp, a chair, and a view of a cityscape through a window.
A multi-story hotel with a modern facade, large windows, and a prominent entrance with a covered area.
A reception area with a marble wall, a 'Free Wireless Internet' sign, and a floral arrangement.

5. Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica
San Francisco
United States
Maria
2.556.494 ₫
2.812.221 ₫ total
includes taxes & fees
6 Oct - 7 Oct
Ramada Plaza by Wyndham Panama Punta Pacifica
A rooftop pool with sun loungers and a city skyline in the background.
A bar area with a curved counter, multiple screens, and a patterned carpet.
A modern hotel room with a large bed, a desk, a chair, and a wardrobe.
A long, narrow hallway with a wooden floor and light-colored walls.

6. Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino
Bella Vista
United States
Abeke
1.853.568 ₫
3.469.750 ₫ total
includes taxes & fees
18 Oct - 19 Oct
Waymore Hotel Spa & Casino
A hotel named PRINCIPE with a modern facade and large glass windows.
A hotel room with a TV mounted on the wall, a large mirror, and a red bedspread.
A swimming pool with lounge chairs and a table.
A hotel reception area with a modern design, featuring a reception desk, white chairs, and a visible fire feature.

7. Principe Hotel and Suites

Principe Hotel and Suites
Bella Vista
United States
Eliel
1.538.267 ₫
1.692.016 ₫ total
includes taxes & fees
17 Oct - 18 Oct
Principe Hotel and Suites
A pool area with lounge chairs and umbrellas, surrounded by greenery and a multi-story building in the background.
A spacious lobby with a curved ceiling, a central staircase, and a reception desk.
A modern interior with a central seating area, potted plants, and a staircase.
A spacious hotel lobby with modern furniture, large windows, and a city view.

8. Hyatt Regency Panama City

Hyatt Regency Panama City
Bella Vista
United States
Abraham
4.864.805 ₫
5.351.286 ₫ total
includes taxes & fees
3 Oct - 4 Oct
Hyatt Regency Panama City
A multi-story building with balconies, arched windows, and decorative railings.
A building with a balcony and a street view.
A spacious lobby with a wooden staircase, multiple seating areas, and a reception desk.
A rooftop swimming pool with lounge chairs, potted plants, and a view of a city skyline including a prominent building with a dome.

9. Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo
Casco Viejo
United States
Olga
4.947.769 ₫
5.442.546 ₫ total
includes taxes & fees
27 Sept - 28 Sept
Central Hotel Panama Casco Viejo
A modern building with a glass facade, a curved structure, and a flat roof.
A spacious lobby with red and blue seating, a large circular wall feature, and a modern design with concrete elements.
A rooftop lounge area with clear glass tables and chairs, a pool, and potted plants.
A modern hotel room with a large bed, a TV, a desk, and a view of the city.

10. Decapolis Hotel Panama City

Decapolis Hotel Panama City
San Francisco
United States
Jorge Luis
2.876.619 ₫
3.164.281 ₫ total
includes taxes & fees
10 Oct - 11 Oct
Decapolis Hotel Panama City
A modern lobby with a chandelier, seating area, reception desk, and a staircase.
A lobby with a reception desk, seating area, and a bar.
A hotel dining area with wicker chairs, a bar counter, and pendant lighting.
A dining area with a glass table, wicker chairs, a plate of fruit, and a cocktail glass.

11. The Executive Hotel

The Executive Hotel
Bella Vista
United States
Sandra
2.307.961 ₫
2.538.757 ₫ total
includes taxes & fees
15 Oct - 16 Oct
The Executive Hotel
A hotel with a pool, beach, and palm trees.
A spacious lobby with a modern design, featuring a central seating area with sofas and ottomans, surrounded by large, open spaces and natural light.
A beachfront hotel with a large building, a beach, and a clear sky.
A spacious lobby with a large seating area, a reception desk, and large windows offering a view of the ocean and palm trees.

12. The Westin Playa Bonita Panama

The Westin Playa Bonita Panama
Veracruz
Canada
Flavio
5.362.722 ₫
5.898.994 ₫ total
includes taxes & fees
2 Oct - 3 Oct
The Westin Playa Bonita Panama
A poolside area with lounge chairs and a covered seating area, reflecting the pool and surrounding structures.
A spacious lobby with a large glass wall offering a view of the forest. There are multiple seating areas and a bar.
An aerial view of a resort with a central building, a circular driveway, and surrounding greenery.
A spacious dining area with large windows offering a view of lush greenery.

13. Summit Rainforest Golf Resort & All Inclusive

Summit Rainforest Golf Resort & All Inclusive
Panama City
United States
Shezara
5.641.483 ₫
6.205.631 ₫ total
includes taxes & fees
4 Oct - 5 Oct
Summit Rainforest Golf Resort & All Inclusive
A spacious lobby with a high ceiling, modern lighting fixtures, and a glass entrance leading to a lower level.
A modern bar area with a central island, bar stools, and a television mounted on the ceiling.
A swimming pool with a clear water surface, surrounded by a covered area with lounge chairs and a bar area.
A modern dining area with a wooden table and chairs, a built-in bookshelf, and a decorative hanging light fixture.

14. Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG
Tocumen Airport
United States
Xenia
3.174.440 ₫
3.663.616 ₫ total
includes taxes & fees
12 Oct - 13 Oct
Crowne Plaza Panama Airport by IHG
A modern hotel room with a sofa, a coffee table, a TV mounted on the wall, and a dining area with a table and chairs.
An indoor swimming pool with lounge chairs and red chairs, surrounded by lush greenery and a modern interior design.
A modern lobby with a staircase, marble flooring, and large windows with tropical plants.
A modern hotel entrance with a prominent 'Renaissance Hotel' sign, a well-lit outdoor area with a wooden structure, and a staircase leading to the upper floors.

15. Renaissance Panama City Hotel

Renaissance Panama City Hotel
Bella Vista
United States
Carlos
3.720.145 ₫
4.092.159 ₫ total
includes taxes & fees
7 Oct - 8 Oct
Renaissance Panama City Hotel
A poolside area with lounge chairs and a view of the ocean.
A modern hotel room with a large bed, a chair, a nightstand with a lamp, and a view of the cityscape at dusk.
A modern bathroom with a large bathtub, two sinks, and a glass-enclosed shower area with a city view.
A terrace with seating and a view of the ocean.

16. JW Marriott Panama

JW Marriott Panama
San Francisco
United States
Nemanja
6.847.148 ₫
7.531.862 ₫ total
includes taxes & fees
24 Oct - 25 Oct
JW Marriott Panama
A buffet with various food items including fruits, juices, and cheeses.
An aerial view of a rectangular swimming pool with two lounge chairs and a ladder.
A modern hotel lobby with a sectional sofa, a glass coffee table, and a vibrant green wall mural.
A hotel reception area with a wooden reception desk, seating area with chairs and ottomans, and a large window providing natural light.

17. Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall
San Antonio
United States
Paula
2.632.718 ₫
2.895.990 ₫ total
includes taxes & fees
16 Oct - 17 Oct
Courtyard by Marriott Panama Metromall
A multi-story hotel with a Marriott sign, surrounded by high-rise buildings and a busy street with cars.
A coastal building complex with multiple structures, a prominent tower, and a beach in the foreground.
A modern cafe with wooden tables and chairs, large windows, and decorative vases on shelves.
A modern reception area with a wooden panel wall, a sign indicating 'Marriott Bonvoy', and three reception desks with digital displays.

18. Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall
San Francisco
United States
Holly
3.068.278 ₫
3.375.106 ₫ total
includes taxes & fees
10 Oct - 11 Oct
Courtyard by Marriott Panama Multiplaza Mall
A rooftop pool area with lounge chairs and a bar, overlooking a city skyline at sunset.
A rooftop terrace with outdoor seating, potted plants, and a view of a hill with buildings in the distance.
A modern hotel lobby with a glass railing, seating area, and contemporary lighting fixtures.
A spacious lobby with high ceilings, large windows, and modern lighting fixtures.

19. Marriott Panama Hotel

Marriott Panama Hotel
Panama City
United States
Richard
4.630.670 ₫
5.093.737 ₫ total
includes taxes & fees
23 Oct - 24 Oct
Marriott Panama Hotel
A modern lobby with a glass railing, a central staircase, and a view of the cityscape through large windows.
A modern living area with a sofa, chairs, and a coffee table. There is a view of the city through large windows.
A spacious lobby with a staircase, seating area, and a bar.
A modern hotel room with a large window offering a city view, a chandelier, and a cozy seating area.

20. Las Americas Golden Tower Panama

Las Americas Golden Tower Panama
San Francisco
United States
Armando
3.952.087 ₫
4.347.296 ₫ total
includes taxes & fees
28 Sept - 29 Sept
Las Americas Golden Tower Panama
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Santa Clara.
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

Plaza de la Independencia Casco Viejo Panama City Panama
5.189.714 ₫
5.708.685 ₫ total
2 Oct - 3 Oct
includes taxes & fees
9/10 Wonderful! (1,000 reviews)
Central Hotel Panama Casco Viejo
Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Hotel El Panama by Faranda Grand, a member of Radisson Individuals

Via Espana 111 Panama City Panama
2.609.806 ₫
2.870.787 ₫ total
29 Sept - 30 Sept
includes taxes & fees
Hotel El Panama by Faranda Grand, a member of Radisson Individuals
Megapolis Hotel Panamá

Megapolis Hotel Panamá

Avenida Balboa Panama City
4.179.383 ₫
4.597.321 ₫ total
24 Sept - 25 Sept
includes taxes & fees
Megapolis Hotel Panamá
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A beach with waves, a boat, and a forested hill in the background.

Top Santa Clara Hotel Reviews

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

10/10 Excellent
"I was a bit disappointed because I recommended my cousin to come there and ask for a birthday decor was told the hotel dont do that but they would do a little birthday token, but they forget nothing was place to even say happy birthday to him , but thats ok just want ever recommended any one again"
Patricia 5-night trip
Posted 1 hour ago
Hotel Riu Plaza Panama
Hyatt Regency Panama City

Hyatt Regency Panama City

8/10 Good
"It’s a very nice and clean hotel Very welcoming"
Stacy-ann 1-night trip
Posted 3 days ago
Hyatt Regency Panama City