Compare and book 5 Star hotels in Vedene, Provence-Alpes-Côte d'Azur

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Check availability on Vedene 5 Star Hotels

Tonight
22 Dec - 23 Dec
Tomorrow
23 Dec - 24 Dec
This weekend
26 Dec - 28 Dec
Next weekend
2 Jan - 4 Jan

Our top choices for Vedene 5-star hotels

Exterior
Hotel d'Europe

Hotel d'Europe

Hotel d'Europe
5.0 star property
Avignon City Centre
9.4 out of 10, Exceptional, (754)
"Dinner at La Vieille Fontaine was really great."
Japan
Yuzuru
The price is 16.135.235 ₫
17.972.466 ₫ total
includes taxes & fees
31 Dec - 1 Jan 2026
Hotel d'Europe
Terrace/patio
La Mirande

La Mirande

La Mirande
5.0 star property
Avignon City Centre
9.4 out of 10, Exceptional, (232)
"Beautiful hotel, kind and courteous staff. Excellent stay! "
United States
Marica
The price is 11.672.834 ₫
13.063.825 ₫ total
includes taxes & fees
24 Dec - 25 Dec
La Mirande
Rosemary Suite, private hot tub | Premium bedding, minibar, in-room safe, individually decorated
Le Vallon de Valrugues Hotel Spa & Villas

Le Vallon de Valrugues Hotel Spa & Villas

Le Vallon de Valrugues Hotel Spa & Villas
5.0 star property
St.-Rémy-de-Provence
8.8 out of 10, Excellent, (285)
"It’s was a beautiful place "
United States
sally
Le Vallon de Valrugues Hotel Spa & Villas
Terrace/patio
Domaine de Manville

Domaine de Manville

Domaine de Manville
5.0 star property
Les Baux-de-Provence
9.6 out of 10, Exceptional, (109)
"So glad I was able to find this place and stayed here for our honeymoon. We would love to stay again. "
Canada
Jung Eun
Domaine de Manville
Indoor pool, seasonal outdoor pool
Hotel Les Bories & Spa

Hotel Les Bories & Spa

Hotel Les Bories & Spa
5.0 star property
Gordes
9.2 out of 10, Wonderful, (201)
"Excellent place to stay! Nice staff, good service, top class restaurant and I also enjoyed the bar and good drinks on the terrass."
Sweden
Christer
The price is 9.524.243 ₫
10.698.526 ₫ total
includes taxes & fees
3 Jan - 4 Jan 2026
Hotel Les Bories & Spa
Indoor spa tub
Baumanière Les Baux de Provence

Baumanière Les Baux de Provence

Baumanière Les Baux de Provence
5.0 star property
Les Baux-de-Provence
9.2 out of 10, Wonderful, (174)
"Incredible hotel. Highly recommend. Staff was amazing."
Canada
Marianne
The price is 9.580.016 ₫
10.857.249 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Baumanière Les Baux de Provence
Couples treatment room(s), sauna, hot tub, steam room
Auberge de Cassagne & Spa

Auberge de Cassagne & Spa

Auberge de Cassagne & Spa
5.0 star property
Le Pontet
9.4 out of 10, Exceptional, (341)
"Amazing food, friendly staff and excellent service. Highly recommended."
United States
Kim
The price is 7.931.477 ₫
8.847.880 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Auberge de Cassagne & Spa
Indoor pool, seasonal outdoor pool, pool umbrellas, pool loungers
Airelles, La Bastide de Gordes

Airelles, La Bastide de Gordes

Airelles, La Bastide de Gordes
5.0 star property
Gordes
9.6 out of 10, Exceptional, (164)
"Awesome place!"
United States
Leon
Airelles, La Bastide de Gordes
Lunch, dinner served; French cuisine, garden views
Hôtel b design & Spa

Hôtel b design & Spa

Hôtel b design & Spa
5.0 star property
Paradou
9.6 out of 10, Exceptional, (90)
"A lovely small hotel in a serene spot - we loved the peace and quite, the room and high level of service - outstanding! "
United States
Susan
Hôtel b design & Spa
Exterior
L'Isle de Leos Hotel & Spa - MGallery Collection

L'Isle de Leos Hotel & Spa - MGallery Collection

L'Isle de Leos Hotel & Spa - MGallery Collection
5.0 star property
L'Isle-sur-la-Sorgue
9.6 out of 10, Exceptional, (5)
"L'Isle de Leos is a fairly new hotel and spa in I'Isle sur la Sorgue and it is spectacular. The property, the staff, the spa, and the location are perfect. It's an easy walk to everywhere in this beautiful village, and after a busy day shopping the many antique shops along the quai, the spa is exceptional with a heated pool, multiple water therapies, dry and steam saunas, an "ice room," and a very cool water "gauntlet" with varying temperatures flooding you as you walk through. While we did not...
United States
Aldus
The price is 8.235.609 ₫
9.282.970 ₫ total
includes taxes & fees
23 Dec - 24 Dec
L'Isle de Leos Hotel & Spa - MGallery Collection
Exclusive Room | Premium bedding, minibar, in-room safe, individually decorated
Le Saint Remy

Le Saint Remy

Le Saint Remy
5.0 star property
St.-Rémy-de-Provence
9.2 out of 10, Wonderful, (57)
"This is one of the best hotels that we ever stayed at. Amazing staff everyone made sure that we have a great stay. They always smiled and treated the guest with graciousness and courtesy meanwhile"
United States
Alhareth
Le Saint Remy
Seasonal outdoor pool, pool umbrellas, pool loungers
Hotel Crillon Le Brave

Hotel Crillon Le Brave

Hotel Crillon Le Brave
5.0 star property
Crillon-le-Brave
9.6 out of 10, Exceptional, (48)
"Beautiful property and excellent staff. Would definitely stay again."
Canada
Dale
Hotel Crillon Le Brave
Terrace/patio
Le Phébus & Spa - Relais & Chateaux

Le Phébus & Spa - Relais & Chateaux

Le Phébus & Spa - Relais & Chateaux
5.0 star property
Joucas
9.2 out of 10, Wonderful, (65)
"Property exceeded our expectations"
Canada
David
Le Phébus & Spa - Relais & Chateaux
Courtyard
Le Prieure - Relais & Chateaux

Le Prieure - Relais & Chateaux

Le Prieure - Relais & Chateaux
5.0 star property
Villeneuve-les-Avignon
9.4 out of 10, Exceptional, (321)
"Excellent location, lovely grounds and well appointed room"
United States
Diane St.
Le Prieure - Relais & Chateaux
Outdoor treatment area, sauna, Turkish bath/hammam, body treatments
Mas des Herbes Blanches Hotel & Spa - Relais & Châteaux

Mas des Herbes Blanches Hotel & Spa - Relais & Châteaux

Mas des Herbes Blanches Hotel & Spa - Relais & Châteaux
5.0 star property
Joucas
9.0 out of 10, Wonderful, (165)
"Beautiful, relaxing property. Great staff. "
United States
Fred
Mas des Herbes Blanches Hotel & Spa - Relais & Châteaux
Seasonal outdoor pool, pool umbrellas, pool loungers
Le Vieux Castillon

Le Vieux Castillon

Le Vieux Castillon
5.0 star property
Castillon-du-Gard
9.6 out of 10, Exceptional, (118)
"Amazing setting and property especially for the value "
United States
Moussa
The price is 3.921.675 ₫
4.498.818 ₫ total
includes taxes & fees
31 Dec - 1 Jan 2026
Le Vieux Castillon
CLEMENT VII Spa & Fitness with Balcony and access to the roof terrace | Terrace/patio
Cloître des Augustins Spa & Fitness

Cloître des Augustins Spa & Fitness

Cloître des Augustins Spa & Fitness
5.0 star property
Avignon City Centre
10.0 out of 10, Exceptional, (3)
"A stopover in Avignon and what a magnificent discovery with its charming old town dominated by such an immense and important historic relic of the Palais des Papes, all the more pleasant to explore in this in-between-tourist-inflows season with its so beautiful weather! And especially staying in this gem of an elegant ground floor apartment with a private terrace overlooking a very flowery and quiet garden - a perfect place to relax after a day's program and to reflect upon... I leave you to...
United States
Alexander
Cloître des Augustins Spa & Fitness
Seasonal outdoor pool
Camping Les Sources

Camping Les Sources

Camping Les Sources
5.0 star property
Courthezon
Camping Les Sources
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Vedene.
Best Western Plus Le Lavarin

Best Western Plus Le Lavarin

1715 Chemin Du Lavarin Sud Avignon Vaucluse
The price is 2.475.190 ₫ per night from 22 Jan to 23 Jan
2.475.190 ₫
2.892.185 ₫ total
22 Jan - 23 Jan 2026
includes taxes & fees
8.8/10 Excellent! (604 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Vedene

Just minutes from Avignon, this charming village offers a golfer's paradise at Grand Avignon Golf with stunning Provençal views. Explore nearby natural wonders like Fontaine-de-Vaucluse Springs or cool off at WAVE ISLAND water park after a sunny afternoon round.

See all hotels in Vedene
Panorama de provence

Top Vedene Hotel Reviews

L'Isle de Leos Hotel & Spa - MGallery Collection

L'Isle de Leos Hotel & Spa - MGallery Collection

10/10 Excellent
"L'Isle de Leos is a fairly new hotel and spa in I'Isle sur la Sorgue and it is spectacular. The property, the staff, the spa, and the location are perfect. It's an easy walk to everywhere in this beautiful village, and after a busy day shopping the many antique shops along the quai, the spa is exceptional with a heated pool, multiple water therapies, dry and steam saunas, an "ice room," and a very cool water "gauntlet" with varying temperatures flooding you as you walk through. While we did not dine in the hotel restaurant (a somewhat limited menu), the breakfast is worth waking up for. Highly recommended! "
Aldus 2-night trip
Posted 3 months ago
L'Isle de Leos Hotel & Spa - MGallery Collection

Frequently asked questions

What are the best 5-star hotels in Vedene?
Unwind in the lap of luxury at Auberge de Cassagne & Spa. Rated highly by Expedia guests for its elevated standard of comfort and grandeur, this 5-star hotel located around the Vaucluse neighbourhood of Vedene surpasses expectations.
How much does it cost to stay in a 5-star hotel in Vedene?
The amount you pay for a 5-star hotel in Vedene depends on things like when you plan to travel and the length of your break. Our top tip for landing the best deal? Use our pricing filters to check out the available options for your chosen dates.

  • Search for the lowest price per night from 2.892.185 ₫

What makes a hotel 5 stars in Vedene?
In Vedene, a hotel needs to offer a certain level of top-notch amenities to be rated 5 stars. These can include saunas and spas, on-site gyms, gourmet restaurants, luxury toiletries, premium bedding and more. What also sets 5-star hotels apart is their extraordinary service. You can look forward to things like concierge services, in-room massages and nightly turn-down services. Some may also offer special touches such as welcome gifts.