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20 Dec - 21 Dec
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Our top choices for American Independence Museum hotels

Coffee/tea maker, electric kettle, toaster
Great Island Inn

Great Island Inn

Great Island Inn
3.5 star property
1.3 km from American Independence Museum
10.0 out of 10, Exceptional, (115)
"Great place, wonderful neighborhood and I would stay there again."
United States
Sean
The price is 3.131.485 ₫
4.261.188 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Great Island Inn
Deluxe Studio Suite, 1 King Bed, Non Smoking, River View | Floor plan
The Water Street Inn

The Water Street Inn

The Water Street Inn
3.5 star property
2.1 km from American Independence Museum
9.8 out of 10, Exceptional, (203)
"Amazing place we are absolutely going back next year. The staff the accommodations, cleanliness bravo"
United States
Anthony
The Water Street Inn
Front of property
The Davenport Inn

The Davenport Inn

The Davenport Inn
4.0 star property
2.3 km from American Independence Museum
9.8 out of 10, Exceptional, (45)
"Absolutely loved this place! Our room was stunning, the staff was wonderful, and had such a great selection of little snacks. I can’t wait for another opportunity to stay here! "
United States
Mariana
The price is 9.177.356 ₫
9.957.431 ₫ total
includes taxes & fees
21 Dec - 22 Dec
The Davenport Inn
Reception
Hampton Inn & Suites Portsmouth Downtown

Hampton Inn & Suites Portsmouth Downtown

Hampton Inn & Suites Portsmouth Downtown
3.0 star property
2.5 km from American Independence Museum
9.6 out of 10, Exceptional, (1089)
"Pleasant staff, clean room, nice gym facilities. "
United States
Danielle
The price is 3.216.266 ₫
3.489.649 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Hampton Inn & Suites Portsmouth Downtown
Premier Apartment, 1 King Bed with Sofa bed, Non Smoking, Kitchen | Private kitchen | Full-sized fridge, microwave, coffee/tea maker, electric kettle
The Inn Downtown

The Inn Downtown

The Inn Downtown
3.5 star property
2.4 km from American Independence Museum
9.6 out of 10, Exceptional, (108)
"We stayed in the penthouse suite. The room was very spacious and clean. The bed was very comfortable as well. We will definitely be staying here again. "
United States
Mark
The price is 4.184.085 ₫
5.530.097 ₫ total
includes taxes & fees
6 Jan - 7 Jan 2026
The Inn Downtown
Front of property
The Hotel Portsmouth

The Hotel Portsmouth

The Hotel Portsmouth
3.0 star property
2.4 km from American Independence Museum
9.4 out of 10, Exceptional, (1002)
"Great location, easy parking, friendly staff. nice property!"
United States
Ralph
The price is 4.239.346 ₫
4.599.690 ₫ total
includes taxes & fees
3 Jan - 4 Jan 2026
The Hotel Portsmouth
Exterior
Martin Hill Inn

Martin Hill Inn

Martin Hill Inn
3.5 star property
3 km from American Independence Museum
9.4 out of 10, Exceptional, (139)
"Great hotel with cute garden ! We stayed in the cathedral room. Very spacious, nicely decorated and comfortable!"
United States
Maria
Martin Hill Inn
Restaurant
AC Hotel by Marriott Portsmouth

AC Hotel by Marriott Portsmouth

AC Hotel by Marriott Portsmouth
3.5 star property
2.7 km from American Independence Museum
9.2 out of 10, Wonderful, (952)
"Very nice hotel "
United States
Yoanny
The price is 3.557.788 ₫
4.574.126 ₫ total
includes taxes & fees
23 Dec - 24 Dec
AC Hotel by Marriott Portsmouth
Desk, laptop workspace, blackout curtains, iron/ironing board
Residence Inn by Marriott Portsmouth Downtown/ Waterfront

Residence Inn by Marriott Portsmouth Downtown/ Waterfront

Residence Inn by Marriott Portsmouth Downtown/ Waterfront
3.0 star property
2.5 km from American Independence Museum
9.0 out of 10, Wonderful, (1000)
"Will definitely stay here again!"
United States
Mary
The price is 3.347.268 ₫
3.631.786 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Residence Inn by Marriott Portsmouth Downtown/ Waterfront
Beach
The Bow Hotel

The Bow Hotel

The Bow Hotel
4.0 star property
2 km from American Independence Museum
8.6 out of 10, Excellent, (502)
"The room at The Bow was lovely, clean and very quiet. Located in a great spot with easy walking to the shops, restaurants and waterfront. Although the room was a little too warm for us for sleeping, the bed and linens were so comfy! "
United States
Katherine
The price is 3.289.375 ₫
3.568.972 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
The Bow Hotel
Outdoor dining
Homewood Suites By Hilton Portsmouth Downtown

Homewood Suites By Hilton Portsmouth Downtown

Homewood Suites By Hilton Portsmouth Downtown
3.0 star property
2.7 km from American Independence Museum
8.8 out of 10, Excellent, (33)
"Clean ever where, knowledgeable and friendly staff and great breakfast."
United States
Brenda
The price is 2.784.553 ₫
3.021.240 ₫ total
includes taxes & fees
29 Dec - 30 Dec
Homewood Suites By Hilton Portsmouth Downtown
Meeting facility
Sheraton Portsmouth Harborside Hotel

Sheraton Portsmouth Harborside Hotel

Sheraton Portsmouth Harborside Hotel
3.5 star property
2.5 km from American Independence Museum
8.6 out of 10, Excellent, (1001)
"Friendly staff, great view and the best clam chowder I have ever had. And I am big fan of clam chowder. "
United States
Tim
The price is 4.002.512 ₫
4.342.725 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Sheraton Portsmouth Harborside Hotel
Aerial view
Hilton Garden Inn Portsmouth Downtown

Hilton Garden Inn Portsmouth Downtown

Hilton Garden Inn Portsmouth Downtown
3.0 star property
2.4 km from American Independence Museum
8.4 out of 10, Very good, (189)
"Clean and great location "
United States
Maria
The price is 3.018.331 ₫
3.274.890 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Hilton Garden Inn Portsmouth Downtown
Terrace/patio
Home2 Suites By Hilton Kittery

Home2 Suites By Hilton Kittery

Home2 Suites By Hilton Kittery
3.0 star property
3.2 km from American Independence Museum
9.4 out of 10, Exceptional, (44)
"Excellent room and facilities "
United States
Krishna Prasad
The price is 2.891.492 ₫
3.151.726 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Home2 Suites By Hilton Kittery
Front of property
Rye Motor Inn: An Adults-Only Apartment Hotel

Rye Motor Inn: An Adults-Only Apartment Hotel

Rye Motor Inn: An Adults-Only Apartment Hotel
3.0 star property
4.1 km from American Independence Museum
9.8 out of 10, Exceptional, (91)
"A wonderful place to stay. "
United States
Timothy
The price is 3.736.730 ₫
4.937.220 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Rye Motor Inn: An Adults-Only Apartment Hotel
Terrace/patio
Hampton Inn & Suites Kittery-Portsmouth

Hampton Inn & Suites Kittery-Portsmouth

Hampton Inn & Suites Kittery-Portsmouth
2.5 star property
4.2 km from American Independence Museum
9.2 out of 10, Wonderful, (1001)
"Great location "
United States
Gary
The price is 2.675.709 ₫
2.916.522 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Hampton Inn & Suites Kittery-Portsmouth
Lobby
Howard Johnson by Wyndham Portsmouth

Howard Johnson by Wyndham Portsmouth

Howard Johnson by Wyndham Portsmouth
2.0 star property
3.9 km from American Independence Museum
8.6 out of 10, Excellent, (1000)
"An awesome place to stay!"
United States
Nicholas
The price is 2.244.406 ₫
2.435.181 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Howard Johnson by Wyndham Portsmouth
Free daily buffet breakfast
Fairfield Inn by Marriott Portsmouth-Seacoast

Fairfield Inn by Marriott Portsmouth-Seacoast

Fairfield Inn by Marriott Portsmouth-Seacoast
2.5 star property
4 km from American Independence Museum
8.6 out of 10, Excellent, (1002)
"Breakfast was great, staff friendly, and room comfortable "
United States
Linda
The price is 2.392.033 ₫
2.595.356 ₫ total
includes taxes & fees
3 Jan - 4 Jan 2026
Fairfield Inn by Marriott Portsmouth-Seacoast
Reception
Courtyard by Marriott in Portsmouth

Courtyard by Marriott in Portsmouth

Courtyard by Marriott in Portsmouth
3.0 star property
4 km from American Independence Museum
8.6 out of 10, Excellent, (932)
"This is my favorite place to stay in the Portsmouth area. "
United States
Gwendolyne
The price is 2.936.754 ₫
3.186.378 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Courtyard by Marriott in Portsmouth
Business centre
Quality Inn Portsmouth West End

Quality Inn Portsmouth West End

Quality Inn Portsmouth West End
2.5 star property
4.4 km from American Independence Museum
8.6 out of 10, Excellent, (1001)
"Nice clean hotel. "
United States
Michael
The price is 3.026.225 ₫
3.283.454 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Quality Inn Portsmouth West End
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top American Independence Museum Hotel Reviews

Home2 Suites By Hilton Kittery

Home2 Suites By Hilton Kittery

10/10 Excellent
"Great new hotel to the Kittery/Portsmouth area. Super convenient. The rooms are huge, clean and well thought out. The staff is very accommodating. And the complimentary breakfast is excellent. Will be back!!!"
Susan 1-night trip
Posted 12 days ago
Home2 Suites By Hilton Kittery
Homewood Suites By Hilton Portsmouth Downtown

Homewood Suites By Hilton Portsmouth Downtown

10/10 Excellent
"Exceptionally clean! The only thing was the air was very dry and it could use a humidifier, but great area in the center of downtown and exceptionally clean"
Mary E. 1-night trip
Posted 3 weeks ago
Homewood Suites By Hilton Portsmouth Downtown

Hotels near other American Independence Museum attractions

Portsmouth_WentworthGardnerandTobiasLearHouses_6079665_05

Wentworth Gardner and Tobias Lear Houses

4.1/5 (12 reviews)
You can browse the exhibits at Wentworth Gardner and Tobias Lear Houses, a museum with a storied past, during your holiday in Portsmouth. Wander the waterfront and beautiful beaches in the area.
See properties
Portsmouth_Portsmouth_PortsmouthHarborLighthouse__01

Portsmouth Harbor Lighthouse

5.0/5 (8 reviews)
You can learn about the history of New Castle with a trip to Portsmouth Harbor Lighthouse. Stroll along the seaside in this family-friendly area or visit its top-notch restaurants.
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Frequently asked questions

What's the area like around American Independence Museum?
American Independence Museum is located in a historic area of New Castle known for its beautiful beaches. If you're looking for a convenient place to stay, take a look at the 12 hotels and other accommodation options you'll find within a mile.
How many hotels are there near American Independence Museum?
Expedia has 12 hotels and other accommodation options within a mile from American Independence Museum.
If I need to cancel the hotel reservation for my stay near American Independence Museum, will I receive a refund?
Yes, you'll find most hotel reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you have a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Add your dates and click on "Search", then you can use the "fully refundable" filter to get the best deals available near American Independence Museum.
What can I see and do near American Independence Museum?
You'll want to browse the collections at Strawbery Banke Museum, Portsmouth Athenaeum and Discover Portsmouth. Market Square, Wentworth Gardner and Tobias Lear Houses and Portsmouth Harbor Lighthouse are some of the notable landmarks to see in the area. You can watch performances at Seacoast Repertory Theatre, The Music Hall and Players Ring Theatre if you're interested in local theatre.

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