Search Hotels Near American Independence Museum, New Castle

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
11 Dec - 12 Dec
Tomorrow
12 Dec - 13 Dec
This weekend
12 Dec - 14 Dec
Next weekend
19 Dec - 21 Dec

Filter by

Guest rating
Guest rating
Star rating

Our top choices for American Independence Museum hotels

Front of property
Great Island Inn

Great Island Inn

Great Island Inn
3.5 star property
1.3 km from American Independence Museum
10.0 out of 10, Exceptional, (115)
"Great place, wonderful neighborhood and I would stay there again."
United States
Sean
The price is 3.136.483 ₫
4.267.989 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Great Island Inn
Lobby
Hampton Inn & Suites Portsmouth Downtown

Hampton Inn & Suites Portsmouth Downtown

Hampton Inn & Suites Portsmouth Downtown
3.0 star property
2.5 km from American Independence Museum
9.6 out of 10, Exceptional, (1096)
"Great hotel! The location was perfect!"
United States
Edward
The price is 2.974.536 ₫
3.227.371 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Hampton Inn & Suites Portsmouth Downtown
Premier Apartment, 1 King Bed with Sofa bed, Non Smoking, Kitchen | Private kitchen | Full-sized fridge, microwave, coffee/tea maker, electric kettle
The Inn Downtown

The Inn Downtown

The Inn Downtown
3.5 star property
2.4 km from American Independence Museum
9.6 out of 10, Exceptional, (108)
"We stayed in the penthouse suite. The room was very spacious and clean. The bed was very comfortable as well. We will definitely be staying here again. "
United States
Mark
The price is 4.190.763 ₫
5.538.924 ₫ total
includes taxes & fees
7 Jan - 8 Jan 2026
The Inn Downtown
Interior entrance
The Hotel Portsmouth

The Hotel Portsmouth

The Hotel Portsmouth
3.0 star property
2.4 km from American Independence Museum
9.4 out of 10, Exceptional, (1000)
"Clean room, clean hotel, friendly staff. Good location for downtown."
United States
David
The price is 4.246.113 ₫
4.607.033 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
The Hotel Portsmouth
Restaurant
AC Hotel by Marriott Portsmouth

AC Hotel by Marriott Portsmouth

AC Hotel by Marriott Portsmouth
3.5 star property
2.7 km from American Independence Museum
9.2 out of 10, Wonderful, (950)
"Very nice hotel "
United States
Yoanny
The price is 3.563.466 ₫
4.581.426 ₫ total
includes taxes & fees
25 Dec - 26 Dec
AC Hotel by Marriott Portsmouth
Property grounds
Kittery Inn and Suites

Kittery Inn and Suites

Kittery Inn and Suites
2.5 star property
2.9 km from American Independence Museum
9.2 out of 10, Wonderful, (1001)
"A nice quiet getaway. Friendly staff. "
United States
Sunil
The price is 1.819.530 ₫
1.983.288 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Kittery Inn and Suites
Lobby
Residence Inn by Marriott Portsmouth Downtown/ Waterfront

Residence Inn by Marriott Portsmouth Downtown/ Waterfront

Residence Inn by Marriott Portsmouth Downtown/ Waterfront
3.0 star property
2.5 km from American Independence Museum
9.0 out of 10, Wonderful, (1000)
"Will definitely stay here again!"
United States
Mary
The price is 3.352.610 ₫
3.637.582 ₫ total
includes taxes & fees
25 Dec - 26 Dec
Residence Inn by Marriott Portsmouth Downtown/ Waterfront
City view from property
The Bow Hotel

The Bow Hotel

The Bow Hotel
4.0 star property
2 km from American Independence Museum
8.6 out of 10, Excellent, (501)
"The room at The Bow was lovely, clean and very quiet. Located in a great spot with easy walking to the shops, restaurants and waterfront. Although the room was a little too warm for us for sleeping, the bed and linens were so comfy! "
United States
Katherine
The price is 3.294.625 ₫
3.574.668 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
The Bow Hotel
Lobby lounge
Sheraton Portsmouth Harborside Hotel

Sheraton Portsmouth Harborside Hotel

Sheraton Portsmouth Harborside Hotel
3.5 star property
2.5 km from American Independence Museum
8.6 out of 10, Excellent, (1001)
"Friendly staff, great view and the best clam chowder I have ever had. And I am big fan of clam chowder. "
United States
Tim
The price is 4.010.877 ₫
4.351.801 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Sheraton Portsmouth Harborside Hotel
Exterior
Hilton Garden Inn Portsmouth Downtown

Hilton Garden Inn Portsmouth Downtown

Hilton Garden Inn Portsmouth Downtown
3.0 star property
2.4 km from American Independence Museum
8.4 out of 10, Very good, (182)
"Excellent location , comfort and service"
United States
Hilda C
The price is 2.846.556 ₫
3.088.514 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Hilton Garden Inn Portsmouth Downtown
Exclusive Penthouse | Room amenity
The Davenport Inn

The Davenport Inn

The Davenport Inn
4.0 star property
2.3 km from American Independence Museum
9.8 out of 10, Exceptional, (45)
"Absolutely loved this place! Our room was stunning, the staff was wonderful, and had such a great selection of little snacks. I can’t wait for another opportunity to stay here! "
United States
Mariana
The price is 9.192.004 ₫
9.973.325 ₫ total
includes taxes & fees
15 Dec - 16 Dec
The Davenport Inn
Exterior
Homewood Suites By Hilton Portsmouth Downtown

Homewood Suites By Hilton Portsmouth Downtown

Homewood Suites By Hilton Portsmouth Downtown
3.0 star property
2.7 km from American Independence Museum
8.8 out of 10, Excellent, (33)
"Clean ever where, knowledgeable and friendly staff and great breakfast."
United States
Brenda
The price is 2.721.384 ₫
2.952.702 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Homewood Suites By Hilton Portsmouth Downtown
Terrace/patio
Home2 Suites By Hilton Kittery

Home2 Suites By Hilton Kittery

Home2 Suites By Hilton Kittery
3.0 star property
3.2 km from American Independence Museum
9.4 out of 10, Exceptional, (40)
"Nice for the money and convenient location to the outlets. "
United States
Justin
The price is 2.825.470 ₫
3.079.763 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Home2 Suites By Hilton Kittery
1 bedroom, premium bedding, pillow-top beds, in-room safe
ViewPoint Hotel

ViewPoint Hotel

ViewPoint Hotel
3.5 star property
15.3 km from American Independence Museum
10.0 out of 10, Exceptional, (132)
"Great views, excellent service, nice pool "
United States
David
The price is 6.562.893 ₫
7.153.553 ₫ total
includes taxes & fees
15 Dec - 16 Dec
ViewPoint Hotel
Lobby
Hampton Inn & Suites Kittery-Portsmouth

Hampton Inn & Suites Kittery-Portsmouth

Hampton Inn & Suites Kittery-Portsmouth
2.5 star property
4.2 km from American Independence Museum
9.2 out of 10, Wonderful, (1000)
"Great location "
United States
Gary
The price is 2.510.424 ₫
2.736.415 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Hampton Inn & Suites Kittery-Portsmouth
Inside Corner King, Third Floor | Living area | TV
The Nevada

The Nevada

The Nevada
3.5 star property
13.9 km from American Independence Museum
9.8 out of 10, Exceptional, (130)
"Hotel was so cute! Staff was super friendly and even sent a message when there was availability to check in early. Had a great stay!"
United States
Haley
The price is 4.190.763 ₫
4.567.932 ₫ total
includes taxes & fees
25 Dec - 26 Dec
The Nevada
Lobby
Residence Inn by Marriott Portsmouth

Residence Inn by Marriott Portsmouth

Residence Inn by Marriott Portsmouth
3.0 star property
6.3 km from American Independence Museum
9.2 out of 10, Wonderful, (283)
"Good location"
United States
Todd
The price is 3.771.687 ₫
4.092.281 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Residence Inn by Marriott Portsmouth
Front of property
Everhome Suites Portsmouth - Newington

Everhome Suites Portsmouth - Newington

Everhome Suites Portsmouth - Newington
2.0 star property
6.5 km from American Independence Museum
9.2 out of 10, Wonderful, (68)
"I enjoyed my stay here! Staff was friendly and helpful! "
United States
Rayanne
The price is 2.890.045 ₫
3.135.699 ₫ total
includes taxes & fees
25 Dec - 26 Dec
Everhome Suites Portsmouth - Newington
Oceanfront Corner King (Oceanview, Upper or Ground Floor) | Living area | 42-inch TV with cable channels, streaming services
Stage Neck Inn

Stage Neck Inn

Stage Neck Inn
4.0 star property
9.9 km from American Independence Museum
9.4 out of 10, Exceptional, (518)
"Excellent place to stay"
United States
Salvatore
The price is 6.984.605 ₫
7.876.790 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Stage Neck Inn
Indoor pool, pool loungers
Hampton Inn Portsmouth Central

Hampton Inn Portsmouth Central

Hampton Inn Portsmouth Central
2.5 star property
5.6 km from American Independence Museum
8.8 out of 10, Excellent, (1008)
"Staff and service was exceptional "
United States
maureen
The price is 2.509.186 ₫
2.722.467 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Hampton Inn Portsmouth Central
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top American Independence Museum Hotel Reviews

Home2 Suites By Hilton Kittery

Home2 Suites By Hilton Kittery

10/10 Excellent
"Very clean room, fantastic HVAC control for the room! Breakfast was great, staff was incredible! Please feel safe and we'll cared for staying here :) "
Leah 1-night trip
Posted 5 days ago
Home2 Suites By Hilton Kittery
Homewood Suites By Hilton Portsmouth Downtown

Homewood Suites By Hilton Portsmouth Downtown

10/10 Excellent
"Exceptionally clean! The only thing was the air was very dry and it could use a humidifier, but great area in the center of downtown and exceptionally clean"
Mary E. 1-night trip
Posted 12 days ago
Homewood Suites By Hilton Portsmouth Downtown

Hotels near other American Independence Museum attractions

Portsmouth_WentworthGardnerandTobiasLearHouses_6079665_05

Wentworth Gardner and Tobias Lear Houses

4.1/5 (12 reviews)
You can browse the exhibits at Wentworth Gardner and Tobias Lear Houses, a museum with a storied past, during your holiday in Portsmouth. Wander the waterfront and beautiful beaches in the area.
See properties
Portsmouth_Portsmouth_PortsmouthHarborLighthouse__01

Portsmouth Harbor Lighthouse

5.0/5 (8 reviews)
You can learn about the history of New Castle with a trip to Portsmouth Harbor Lighthouse. Stroll along the beautiful beaches in this family-friendly area or visit its top-notch restaurants.
See properties

Frequently asked questions

What's the area like around American Independence Museum?
American Independence Museum is located in a historic area of New Castle known for its beautiful beaches. If you're looking for a convenient place to stay, take a look at the 12 hotels and other accommodation options you'll find within a mile.
How many hotels are there near American Independence Museum?
Expedia has 12 hotels and other accommodation options within a mile from American Independence Museum.
If I need to cancel the hotel reservation for my stay near American Independence Museum, will I receive a refund?
Yes, you'll find most hotel reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you have a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Add your dates and click on "Search", then you can use the "fully refundable" filter to get the best deals available near American Independence Museum.
What can I see and do near American Independence Museum?
You'll want to browse the collections at Strawbery Banke Museum, Discover Portsmouth and Portsmouth Athenaeum. Market Square, Wentworth Gardner and Tobias Lear Houses and Portsmouth Harbor Lighthouse are some of the notable landmarks to see in the area. You can watch performances at Seacoast Repertory Theatre, The Music Hall and Players Ring Theatre if you're interested in local theatre.

Explore a world of travel with Expedia