Search Hotels in Barrio de Guadalupe, San Cristóbal de las Casas

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
20 Dec - 21 Dec
Tomorrow
21 Dec - 22 Dec
Next weekend
26 Dec - 28 Dec
In two weeks
2 Jan - 4 Jan

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Barrio de Guadalupe hotels

Superior Villa | Living area | Fireplace
Jungla Hotel Boutique

Jungla Hotel Boutique

Jungla Hotel Boutique
2.0 star property
Barrio de Guadalupe
10.0 out of 10, Exceptional, (2)
"Todo"
Mexico
Rodolfo antonio
The price is 1.444.156 ₫
1.704.104 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Jungla Hotel Boutique
Garden
Casavieja

Casavieja

Casavieja
4.0 star property
Barrio de Guadalupe
8.8 out of 10, Excellent, (332)
"Good location and nice staff "
Canada
Max
Casavieja
Property entrance
Taller de Juan - Casa Hotel

Taller de Juan - Casa Hotel

Taller de Juan - Casa Hotel
3.5 star property
Barrio de Guadalupe
9.6 out of 10, Exceptional, (64)
"We loved the staff and the attention to detail. "
United States
Refugio
Taller de Juan - Casa Hotel
Interior detail
Hotel Ocho Barrios

Hotel Ocho Barrios

Hotel Ocho Barrios
3.0 star property
Barrio de Guadalupe
9.2 out of 10, Wonderful, (32)
"The location was excellent.My room was spacious and comfortable, staff very friendly and breakfast was delicious"
United States
Eduardo
The price is 1.247.858 ₫
1.546.095 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Hotel Ocho Barrios
Living area
Hotel Tepeyac

Hotel Tepeyac

Hotel Tepeyac
3.0 star property
Barrio de Guadalupe
9.0 out of 10, Wonderful, (132)
"Great location, although need to be mindful of the noise at night due to parties and nightlife. The property was very beautiful, tidy and staff were super friendly. "
Canada
Raul
Hotel Tepeyac
32-inch flat-screen TV with satellite channels, TV
Yox Hotel Boutique

Yox Hotel Boutique

Yox Hotel Boutique
2.5 star property
Barrio de Guadalupe
9.4 out of 10, Exceptional, (96)
"Location is perfect everything close to the hotel "
United States
Jose
The price is 1.237.463 ₫
1.460.206 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Yox Hotel Boutique
Standard Quadruple Room | Premium bedding, down duvets, desk, free WiFi
Hotel Casa del Sol

Hotel Casa del Sol

Hotel Casa del Sol
2.5 star property
Barrio de Guadalupe
8.8 out of 10, Excellent, (6)
"Friendly good but need to change more details "
United States
wook
The price is 1.094.057 ₫
1.290.987 ₫ total
includes taxes & fees
20 Jan - 21 Jan 2026
Hotel Casa del Sol
Outdoor dining
Hotel Parador Margarita

Hotel Parador Margarita

Hotel Parador Margarita
3.5 star property
Barrio de Guadalupe
9.0 out of 10, Wonderful, (145)
"One of the best places I’ve stayed in San Cristobal — old and charming building, but comfortable rooms with modern amenities. Friendly staff, lovely area — central but not noisy."
Canada
Jessica
The price is 1.312.869 ₫
1.549.185 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Hotel Parador Margarita
Rooftop terrace
Hotel Jovel

Hotel Jovel

Hotel Jovel
3.0 star property
Barrio de Guadalupe
8.0 out of 10, Very good, (107)
"NO ME AGRADO QUE EL ESTACIONAMIENTO ESTÁ A DOS CIADRAS Y EL HORARIO ES LIMITADO."
Mexico
ALEJANDRO
The price is 860.659 ₫
1.015.578 ₫ total
includes taxes & fees
10 Jan - 11 Jan 2026
Hotel Jovel
Interior
Tierra Alta Hostal

Tierra Alta Hostal

Tierra Alta Hostal
3.0 star property
Barrio de Guadalupe
9.6 out of 10, Exceptional, (13)
"I stayed here last week and loved it so much I came back. Everything about this place is exceptional. This will be my to-go place to stay while in San Cris. "
United States
Damaris
Tierra Alta Hostal
Double Room, 2 Queen Beds | Iron/ironing board, free WiFi, bed sheets
Hotel Cielo y Selva, San Cristobal de las Casas

Hotel Cielo y Selva, San Cristobal de las Casas

Hotel Cielo y Selva, San Cristobal de las Casas
3.0 star property
Barrio de Guadalupe
8.6 out of 10, Excellent, (112)
"The staff was very friendly and helpful all the time!"
United States
MAYRA
The price is 1.100.636 ₫
1.298.748 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Hotel Cielo y Selva, San Cristobal de las Casas
Basic Triple Room | Free WiFi
Yagil B&B

Yagil B&B

Yagil B&B
2.0 star property
Barrio de Guadalupe
The price is 984.652 ₫
1.161.889 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Yagil B&B
Property amenity
Hotel Sombra del Agua

Hotel Sombra del Agua

Hotel Sombra del Agua
3.5 star property
Zona Centro, 1 km from Barrio de Guadalupe
9.4 out of 10, Exceptional, (1003)
"Fantastic location & beautiful colonial building."
United Kingdom
Julia
The price is 2.290.720 ₫
2.703.049 ₫ total
includes taxes & fees
18 Jan - 19 Jan 2026
Hotel Sombra del Agua
Terrace/patio
Hotel Casa Linda

Hotel Casa Linda

Hotel Casa Linda
2.0 star property
Santa Lucía, 1.2 km from Barrio de Guadalupe
9.0 out of 10, Wonderful, (4)
"Excelente servicio, el personal de recepción muy amable, las habitaciones muy limpias y cómodas. "
Mexico
Andrea del Rosario
The price is 752.668 ₫
888.156 ₫ total
includes taxes & fees
6 Jan - 7 Jan 2026
Hotel Casa Linda
Building design
Casa del Alma Hotel Boutique & Spa

Casa del Alma Hotel Boutique & Spa

Casa del Alma Hotel Boutique & Spa
4.0 star property
Barrio de La Merced, 1.1 km from Barrio de Guadalupe
9.6 out of 10, Exceptional, (313)
"All staff of this hotel is Amazing! I really thank them for their hospitality and service to us. "
United States
Selene
The price is 5.054.546 ₫
5.964.364 ₫ total
includes taxes & fees
18 Jan - 19 Jan 2026
Casa del Alma Hotel Boutique & Spa
Garden Family Kuxel Room | Premium bedding, in-room safe, soundproofing, iron/ironing board
Casa Lum

Casa Lum

Casa Lum
3.5 star property
Zona Centro, 0.7 km from Barrio de Guadalupe
9.8 out of 10, Exceptional, (167)
"Location, locationcleanliness, friendly staff and comfortable bed. "
United States
Maria
The price is 3.416.012 ₫
4.030.901 ₫ total
includes taxes & fees
2 Jan - 3 Jan 2026
Casa Lum
Aerial view
Hotel Bo

Hotel Bo

Hotel Bo
4.0 star property
Barrio de Mexicanos, 1.2 km from Barrio de Guadalupe
9.8 out of 10, Exceptional, (286)
"Excelente hotel"
Mexico
Claudia
The price is 10.837.004 ₫
12.787.665 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Hotel Bo
Mexican cuisine
Hotel Diego de Mazariegos

Hotel Diego de Mazariegos

Hotel Diego de Mazariegos
4.0 star property
Zona Centro, 0.9 km from Barrio de Guadalupe
8.8 out of 10, Excellent, (540)
"Room was clean, at night it was very noisy outside the room so it’s hard to sleep "
United States
Luis P
The price is 1.129.361 ₫
1.332.646 ₫ total
includes taxes & fees
20 Jan - 21 Jan 2026
Hotel Diego de Mazariegos
Junior Suite, Garden View | 1 bedroom, soundproofing, bed sheets
Cabañas y Suites Sergia Torres

Cabañas y Suites Sergia Torres

Cabañas y Suites Sergia Torres
3.0 star property
8.3 km from Barrio de Guadalupe
8.8 out of 10, Excellent, (23)
"Batañamos con el gas "
Mexico
Benika
The price is 1.561.001 ₫
1.841.984 ₫ total
includes taxes & fees
12 Jan - 13 Jan 2026
Cabañas y Suites Sergia Torres
Terrace/patio
Guayaba Inn Boutique Hotel

Guayaba Inn Boutique Hotel

Guayaba Inn Boutique Hotel
4.0 star property
Barrio del Cerrillo, 0.4 km from Barrio de Guadalupe
9.8 out of 10, Exceptional, (259)
"T"
Mexico
Francisco
The price is 2.757.025 ₫
3.253.289 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Guayaba Inn Boutique Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Barrio de Guadalupe

Find the best Barrio de Guadalupe areas for the activities you enjoy most.
San Cristobal de las Casas which includes heritage elements

Zona Centro

Unique features of Zona Centro include the museums and gardens. Make a stop by Mesoamerican Museum of Jade or Foro Cultural Kinoki while you're exploring the area.

Arches of Carmen which includes cycling and heritage elements as well as an individual male

Santa Lucía

If you're spending some time in Santa Lucía, Santo Domingo Handicraft Market and Arches of Carmen are top sights worth seeing.

Barrio de La Merced

While visiting Barrio de La Merced, you might make a stop by sights like Amber Museum of Chiapas and Regional Costume Museum.

San Cristobal de las Casas showing interior views

Barrio del Cerrillo

If you're spending some time in Barrio del Cerrillo, Na Bolom Cultural Museum and Ex-Convent of Santo Domingo are top sights worth seeing.

De Cuxtitali

If you're looking for some top things to see and do in De Cuxtitali and surrounding area, you can visit Na Bolom Cultural Museum and Ex-Convent of Santo Domingo.

Top Barrio de Guadalupe Hotel Reviews

Frequently asked questions

What is Barrio de Guadalupe like?
You'll be sure to have fun exploring San Cristóbal de las Casas's Barrio de Guadalupe neighbourhood.
How many hotels are there in the Barrio de Guadalupe area?
Expedia has 61 hotels and other accommodation options in Barrio de Guadalupe to choose from, making this an ideal home base for exploring the greater San Cristóbal de las Casas area.
If I need to cancel my hotel reservation in Barrio de Guadalupe, will I receive a refund?
Yes, most hotel room reservations are refundable provided that you cancel before the hotel's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you have a reservation that's non-refundable, you might still have the option to cancel and be given a refund within a 24-hour period of booking. Plug in your dates, click on "Search", then you can filter by "fully refundable" to view the best options available in Barrio de Guadalupe.
What is there to do in this San Cristóbal de las Casas neighbourhood?
A few places to visit in the area around Barrio de Guadalupe include Na Bolom Cultural Museum, Galeria Studio Cerrillo and Foro Cultural Kinoki. Café Museo Café and Church of San Nicolás are also worth a visit when you're out sightseeing in San Cristóbal de las Casas.