Cape Girardeau Holidays
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Top hotels in Cape Girardeau
Drury Plaza Hotel Cape Girardeau Conference Center
3351 Percy Drive Cape Girardeau MO
Fully refundableReserve now, pay when you stay
The price is 2.363.677 ₫ per night from 19 Jan to 20 Jan
2.363.677 ₫
2.666.261 ₫ total
19 Jan - 20 Jan
includes taxes & fees
9.4/10 Exceptional! (1,004 reviews)
Clean
Reviewed on 8 Jan 2026
The Riverview
777 Main St Cape Girardeau MO
Fully refundableReserve now, pay when you stay
The price is 2.529.416 ₫ per night from 14 Jan to 15 Jan
2.529.416 ₫
2.853.535 ₫ total
14 Jan - 15 Jan
includes taxes & fees
9.2/10 Wonderful! (488 reviews)
Room was spotless. The whole hotel was clean and the staff were very kind.
Reviewed on 9 Jan 2026
Drury Inn & Suites Cape Girardeau
3303 Campster Drive Cape Girardeau MO
Fully refundableReserve now, pay when you stay
The price is 2.363.677 ₫ per night from 19 Jan to 20 Jan
2.363.677 ₫
2.666.261 ₫ total
19 Jan - 20 Jan
includes taxes & fees
9.4/10 Exceptional! (1,011 reviews)
All the above!
Reviewed on 6 Jan 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular places to visit
Southeast Missouri State University
Take a campus tour or just explore the area of Southeast Missouri State University during your trip to Cape Girardeau. While in this family-friendly area, you can savour the top-notch restaurants.
Riverfront Bridge Park
Riverfront Bridge Park is just one of the places to see in Cape Girardeau, so why not enjoy the other things to explore during your travels? While in this family-friendly area, you can savour the top-notch restaurants.
Hunter Valley Winery
You can enjoy a tasting or tour at Hunter Valley Winery during your travels to Cape Girardeau. While in this family-friendly area, you can savour the top-notch restaurants.
