
Cape Girardeau Holidays
Book a Hotel + Flight or Car together to unlock savings
Top hotels in Cape Girardeau

Drury Plaza Hotel Cape Girardeau Conference Center
3351 Percy Drive Cape Girardeau MO
Fully refundableReserve now, pay when you stay
The price is 2.372.316 ₫ per night from 1 Dec to 2 Dec
2.372.316 ₫
2.676.006 ₫ total
1 Dec - 2 Dec
includes taxes & fees
9.4/10 Exceptional! (1,002 reviews)
Breakfast and super Kickoff was AWESOME? love this hotel!!!
Reviewed on 23 Nov 2025

The Riverview
777 Main St Cape Girardeau MO
Fully refundableReserve now, pay when you stay
The price is 2.538.661 ₫ per night from 26 Nov to 27 Nov
2.538.661 ₫
2.863.966 ₫ total
26 Nov - 27 Nov
includes taxes & fees
9.4/10 Exceptional! (458 reviews)
Great room, close to downtown, awesome food options in the venue as well. Really nice views of the river.
Reviewed on 19 Nov 2025

Pear Tree Inn Cape Girardeau West
103 Cape West Pkwy Cape Girardeau MO
Fully refundableReserve now, pay when you stay
The price is 1.845.076 ₫ per night from 30 Nov to 1 Dec
1.845.076 ₫
2.081.543 ₫ total
30 Nov - 1 Dec
includes taxes & fees
9/10 Wonderful! (1,002 reviews)
Everything was great.
Reviewed on 21 Nov 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular places to visit
Southeast Missouri State University
Take a campus tour or just explore the area of Southeast Missouri State University during your trip to Cape Girardeau. While in this family-friendly area, you can savour the top-notch restaurants.
Riverfront Bridge Park
Riverfront Bridge Park is just one of the places to see in Cape Girardeau, so why not enjoy the other things to explore during your travels? While in this family-friendly area, you can savour the top-notch restaurants.
Cape Splash Family Aquatic Center
Bring the children to Cape Splash Family Aquatic Center and have a fun-filled day at this theme park in Cape Girardeau. While in this family-friendly area, you can savour the top-notch restaurants.
