Cape Girardeau Holidays
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Top hotels in Cape Girardeau
Drury Plaza Hotel Cape Girardeau Conference Center
3351 Percy Drive, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
The price is 2.372.316 ₫ per night from 19 Oct to 20 Oct
2.372.316 ₫
2.676.006 ₫ total
19 Oct - 20 Oct
includes taxes & fees
9.4/10 Exceptional! (1,012 reviews)
"The lady that checked me in was amazing!"
Reviewed on 6 Oct 2025
The Riverview
777 Main St, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
The price is 3.250.435 ₫ per night from 19 Oct to 20 Oct
3.250.435 ₫
3.666.946 ₫ total
19 Oct - 20 Oct
includes taxes & fees
9.2/10 Wonderful! (431 reviews)
"The rooms are always amazing! When we go in its always so nice and cool. Loved having a k-cup in my room again. This is my favorite place in cape. My only complaint would be no microwave in the room for snacks and things."
Reviewed on 6 Oct 2025
Pear Tree Inn Cape Girardeau Near the Medical Center
3248 William St, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
The price is 1.845.076 ₫ per night from 12 Oct to 13 Oct
1.845.076 ₫
2.081.543 ₫ total
12 Oct - 13 Oct
includes taxes & fees
8.8/10 Excellent! (1,003 reviews)
"Convenient to St Francis Medical Center. It is quiet, staff is friendly and tge breakfast a plus"
Reviewed on 2 Oct 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular places to visit
Southeast Missouri State University
Take a campus tour or just explore the area of Southeast Missouri State University during your trip to Cape Girardeau. While in this family-friendly area, you can savour the top-notch restaurants.
Riverfront Bridge Park
Riverfront Bridge Park is just one of the places to see in Cape Girardeau, so why not enjoy the other things to explore during your travels? While in this family-friendly area, you can savour the top-notch restaurants.
Cape Splash Family Aquatic Center
Bring the children to Cape Splash Family Aquatic Center and have a fun-filled day at this theme park in Cape Girardeau. While in this family-friendly area, you can savour the top-notch restaurants.
