Central San Diego Holidays

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Where to stay in Central San Diego

Find the best Central San Diego areas and neighborhoods for the activities you enjoy most. Learn more about Central San Diego

Top hotels in Central San Diego

Hampton Inn San Diego/Mission Valley

Hampton Inn San Diego/Mission Valley

2.5 out of 5
2151 Hotel Circle South San Diego CA
Fully refundableReserve now, pay when you stay
The price is 2.636.300 ₫ per night from 5 Jan to 6 Jan
2.636.300 ₫
3.030.295 ₫ total
5 Jan - 6 Jan 2026
includes taxes & fees
8.6/10 Excellent! (1,273 reviews)
Spacious and clean rooms, helpful staff

Reviewed on 2 Dec 2025

Hampton Inn San Diego/Mission Valley
Sheraton Mission Valley San Diego Hotel

Sheraton Mission Valley San Diego Hotel

4 out of 5
1433 Camino Del Rio S San Diego CA
Fully refundableReserve now, pay when you stay
The price is 3.110.834 ₫ per night from 11 Dec to 12 Dec
3.110.834 ₫
3.575.749 ₫ total
11 Dec - 12 Dec
includes taxes & fees
8.4/10 Very Good! (1,642 reviews)
Great hotel! Very centric.

Reviewed on 2 Dec 2025

Sheraton Mission Valley San Diego Hotel
Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa

4 out of 5
875 Hotel Circle South San Diego CA
Fully refundableReserve now, pay when you stay
The price is 4.011.130 ₫ per night from 7 Dec to 8 Dec
4.011.130 ₫
4.610.593 ₫ total
7 Dec - 8 Dec
includes taxes & fees
9/10 Wonderful! (2,947 reviews)
The room was very clean.

Reviewed on 1 Dec 2025

Legacy Resort Hotel & Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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