Find hotels in Central San Diego, CA from 2.214.492 ₫
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Go beyond your typical stay in Central San Diego
Apart hotel
Check prices for these dates
Top 10 Central San Diego hotels and places to stay
Hampton Inn San Diego/Mission Valley
Mission Valley
8.8 out of 10, Excellent, (1269)
"Spacious and clean rooms, helpful staff"
Gholam
The price is 2.636.300 ₫
3.030.295 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Hilton Garden Inn San Diego Old Town/SeaWorld Area
Old Town San Diego
8.6 out of 10, Excellent, (1279)
"Good location, the room was specious and clean. We really enjoyed our stay!"
Yana
The price is 2.678.481 ₫
3.078.780 ₫ total
includes taxes & fees
18 Dec - 19 Dec
Comfort Inn San Diego Old Town
Old Town San Diego
8.2 out of 10, Very good, (1913)
"Efficient check in, clean rooms and great breakfast."
Wendy
The price is 2.576.983 ₫
2.962.113 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Handlery Hotel
Mission Valley
8.2 out of 10, Very good, (2209)
"Staff was amazing and very accommodating. Always recommended staying here. "
Taja
Courtyard by Marriott Old Town
Old Town San Diego
8.6 out of 10, Excellent, (1003)
"Nice staying there "
Jennifer
The price is 3.142.470 ₫
3.612.113 ₫ total
includes taxes & fees
19 Dec - 20 Dec
Kings Inn San Diego
Mission Valley
8.8 out of 10, Excellent, (3568)
"Room was very clean, and the breakfast was good"
Roxana
The price is 2.076.087 ₫
2.382.310 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Great weekend hotel deals in Central San Diego, CA
Showing deals for:19 Dec - 21 Dec
Image gallery for City24 Hotel Little Italy Mission Hills
City24 Hotel Little Italy Mission Hills
San Diego
9.6/10Exceptional (104 reviews)
30% off
Price is 8.100.193 ₫
19.162.276 ₫ total
includes taxes & fees
Save an average of 15% on thousands of hotels when you're signed in
Stay near popular Southern California attractions
Learn more about Central San Diego
Explore the seaside area of Central San Diego—beaches, sports teams and popular sights like San Diego Zoo.
Top Central San Diego Hotel Reviews
More cheap stays in Central San Diego
Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
2485 Hotel Circle Place San Diego CA
The price is 3.130.606 ₫ per night from 14 Dec to 15 Dec
3.130.606 ₫
3.598.319 ₫ total
14 Dec - 15 Dec
includes taxes & fees
8/10 Very Good! (2,300 reviews)
Hotels in Central San Diego with star rating
4 Star Hotels
13 properties
2 Star Hotels
60 properties
Explore a world of travel with Expedia
Areas of Central San Diego
- Hotels in Downtown San Diego
- Hotels in Point Loma
- Hotels in Mission Valley
- Hotels in Mission Bay
- Hotels in Little Italy
- Hotels in Del Cerro
- Hotels in Old Town San Diego
- Hotels in North Park
- Hotels in East Village
- Hotels in Hillcrest
- Hotels in Mid-City
- Hotels in Linda Vista
- Hotels in Torrey Pines
- Hotels in University City
- Hotels in Bay Park
- Hotels in Clairemont
- Hotels in Bankers Hill
- Hotels in Mission Hills
- Hotels in Mira Mesa
- Hotels in Miramar
Accommodation near Central San Diego attractions
- Hotels near San Diego Zoo
- Hotels near Balboa Park
- Hotels near Hotel Circle
- Hotels near San Diego State University
- Hotels near Snapdragon Stadium
- Hotels near Fashion Valley Mall
- Hotels near Westfield UTC
- Hotels near Scripps Memorial Hospital La Jolla
- Hotels near San Diego Natural History Museum
- Hotels near Mission Valley Mall
- Hotels near San Diego Mormon Temple
- Hotels near Convoy District
- Hotels near Cal Coast Credit Union Open Air Theater
- Hotels near San Diego Air and Space Museum
- Hotels near Old Globe Theater
- Hotels near Adams Avenue Park
- Hotels near Japanese Friendship Garden
Choose Your Central San Diego Hotel Style
- Beach Resorts & Hotels in Central San Diego
- Business Hotels in Central San Diego
- Cheap Hotels in Central San Diego
- Family-Friendly Hotels in Central San Diego
- Golf Hotels in Central San Diego
- Historic Hotels in Central San Diego
- Hotels Suites in Central San Diego
- Hotels near Museums in Central San Diego
- Hotels with Air Conditioning in Central San Diego
- Hotels with Balcony in Central San Diego
- Hotels with Breakfast in Central San Diego
- Hotels with Connecting Rooms in Central San Diego
- Hotels with Entertainment in Central San Diego
- Hotels with Gym in Central San Diego
- Hotels with Hot Tubs in Central San Diego
- Hotels with Laundry Service in Central San Diego
- Hotels with Parking in Central San Diego
- Hotels with Parking in Central San Diego
- Hotels with Pool in Central San Diego
- Hotels with Restaurant in Central San Diego
- Hotels with Room Service in Central San Diego
- Hotels with Wifi in Central San Diego
- Hotels with a Bar in Central San Diego
- Hotels with a View in Central San Diego
- Luxury Hotels in Central San Diego
- Marina Hotels in Central San Diego
- Pet-Friendly Hotels in Central San Diego
- Romantic Hotels in Central San Diego
- Shopping Hotels in Central San Diego
- Spa Hotels in Central San Diego
- Sports Hotels in Central San Diego
- Wedding Hotels in Central San Diego
Hotels near Central San Diego Airports
Search Central San Diego Hotel Brands
Hotels Near Central San Diego, San Diego
- San Diego Hotels
- Carlsbad Hotels
- Oceanside Hotels
- La Jolla Hotels
- Chula Vista Hotels
- Coronado Hotels
- Encinitas Hotels
- Del Mar Hotels
- Escondido Hotels
- El Cajon Hotels
- Vista Hotels
- Cardiff-by-the-Sea Hotels
- San Marcos Hotels
- National City Hotels
- Solana Beach Hotels
- San Ysidro Hotels
- La Mesa Hotels
- Rancho Santa Fe Hotels
- Imperial Beach Hotels
- Poway Hotels
