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Search Hotels in Cherokee Seneca, Louisville

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Our top choices for Cherokee Seneca hotels

Lobby
Drury Inn & Suites Louisville East

Drury Inn & Suites Louisville East

Drury Inn & Suites Louisville East
3.0 star property
9.3 km from Cherokee Seneca
9.4 out of 10, Exceptional, (1001)
"Room was great,staff was awsome,food delicious. "
United States
Daniel
The price is 2.367.367 ₫
2.785.385 ₫ total
includes taxes & fees
18 Dec - 19 Dec
Drury Inn & Suites Louisville East
Exterior
Courtyard by Marriott Louisville Airport

Courtyard by Marriott Louisville Airport

Courtyard by Marriott Louisville Airport
3.0 star property
7.1 km from Cherokee Seneca
9.0 out of 10, Wonderful, (329)
"Staff were very nice and airport shuttle was prompt "
United States
Alexandria
The price is 2.578.086 ₫
3.033.375 ₫ total
includes taxes & fees
19 Dec - 20 Dec
Courtyard by Marriott Louisville Airport
4 restaurants, breakfast, lunch, dinner served; American cuisine
Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham
4.0 star property
Downtown Louisville, 6.5 km from Cherokee Seneca
9.0 out of 10, Wonderful, (3852)
"Beautiful room and great hospitality. "
United States
Chase
The price is 3.506.723 ₫
4.126.010 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Galt House Hotel Trademark Collection by Wyndham
Beach
Hilton Garden Inn Louisville/Northeast

Hilton Garden Inn Louisville/Northeast

Hilton Garden Inn Louisville/Northeast
3.0 star property
12.5 km from Cherokee Seneca
9.0 out of 10, Wonderful, (227)
"Alway good!"
United States
Edward
The price is 1.873.058 ₫
2.203.737 ₫ total
includes taxes & fees
10 Jan - 11 Jan 2026
Hilton Garden Inn Louisville/Northeast
Sauna, body treatments, aromatherapy, hot stone massages
Omni Louisville Hotel

Omni Louisville Hotel

Omni Louisville Hotel
4.0 star property
Downtown Louisville, 6.2 km from Cherokee Seneca
9.2 out of 10, Wonderful, (1728)
"This is a beautiful hotel in a great location. Very kind staff and helpful with directions."
United States
Bonnie
The price is 4.398.741 ₫
5.175.559 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Omni Louisville Hotel
Premium bedding, in-room safe, desk, laptop workspace
Derby City Gaming & Hotel - A Churchill Downs Property

Derby City Gaming & Hotel - A Churchill Downs Property

Derby City Gaming & Hotel - A Churchill Downs Property
4.0 star property
6 km from Cherokee Seneca
9.4 out of 10, Exceptional, (1688)
"Great place to stay"
United States
april
Derby City Gaming & Hotel - A Churchill Downs Property
Interior entrance
Wingate by Wyndham Louisville Fair and Expo

Wingate by Wyndham Louisville Fair and Expo

Wingate by Wyndham Louisville Fair and Expo
2.5 star property
3.7 km from Cherokee Seneca
8.4 out of 10, Very good, (1177)
"Place was nice and staff very friendly"
United States
Thelma
The price is 1.705.856 ₫
2.007.109 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Wingate by Wyndham Louisville Fair and Expo
Exterior
Holiday Inn Express & Suites Louisville Downtown by IHG

Holiday Inn Express & Suites Louisville Downtown by IHG

Holiday Inn Express & Suites Louisville Downtown by IHG
2.5 star property
Downtown Louisville, 7.1 km from Cherokee Seneca
8.8 out of 10, Excellent, (1652)
"Great place I would definitely book again"
United States
Lisa
The price is 2.157.174 ₫
2.538.130 ₫ total
includes taxes & fees
16 Dec - 17 Dec
Holiday Inn Express & Suites Louisville Downtown by IHG
Desk, laptop workspace, blackout curtains, bed sheets
Studio 6 Suites Louisville, KY – Airport/Expo Center

Studio 6 Suites Louisville, KY – Airport/Expo Center

Studio 6 Suites Louisville, KY – Airport/Expo Center
2.0 star property
7.5 km from Cherokee Seneca
7.2 out of 10, Good, (507)
"Staff was very friendly and helpful"
United States
Sandra
The price is 1.537.877 ₫
1.809.466 ₫ total
includes taxes & fees
25 Dec - 26 Dec
Studio 6 Suites Louisville, KY – Airport/Expo Center
In-room safe, desk, blackout curtains, iron/ironing board
Crowne Plaza Louisville Airport Expo Ctr by IHG

Crowne Plaza Louisville Airport Expo Ctr by IHG

Crowne Plaza Louisville Airport Expo Ctr by IHG
3.5 star property
Fairgrounds, 7 km from Cherokee Seneca
8.8 out of 10, Excellent, (1026)
"Great place to stay!"
United States
Steven
The price is 2.730.317 ₫
3.212.491 ₫ total
includes taxes & fees
12 Jan - 13 Jan 2026
Crowne Plaza Louisville Airport Expo Ctr by IHG
Lobby
Hawthorn Suites by Wyndham Louisville East

Hawthorn Suites by Wyndham Louisville East

Hawthorn Suites by Wyndham Louisville East
3.0 star property
St. Matthews, 5.2 km from Cherokee Seneca
8.8 out of 10, Excellent, (1037)
"The room was very clean, check in was easy and staff was friendly and helpful."
United States
Melody
The price is 2.606.571 ₫
3.067.065 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Hawthorn Suites by Wyndham Louisville East
Standard Room, 2 Queen Beds, Non Smoking | Desk, iron/ironing board, free cots/infant beds, rollaway beds
Microtel Inn by Wyndham Louisville East

Microtel Inn by Wyndham Louisville East

Microtel Inn by Wyndham Louisville East
2.0 star property
Jeffersontown, 12.6 km from Cherokee Seneca
6.8 out of 10, (1004)
"Clean room, friendly staff and good breakfast. Would definitely stay again."
United States
Crandell
The price is 1.677.597 ₫
1.974.077 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Microtel Inn by Wyndham Louisville East
Iron/ironing board, free WiFi, bed sheets
Staybridge Suites Louisville Expo Center by IHG

Staybridge Suites Louisville Expo Center by IHG

Staybridge Suites Louisville Expo Center by IHG
3.0 star property
Fairgrounds, 7.2 km from Cherokee Seneca
9.2 out of 10, Wonderful, (491)
"Check in was great, staff is amazing and room had everything you could need."
United States
Jeffrey
The price is 3.130.533 ₫
3.992.914 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Staybridge Suites Louisville Expo Center by IHG
Lobby
Ramada by Wyndham Sellersburg/Louisville North

Ramada by Wyndham Sellersburg/Louisville North

Ramada by Wyndham Sellersburg/Louisville North
2.5 star property
18.6 km from Cherokee Seneca
8.4 out of 10, Very good, (1000)
"Clean room, helpful staff, good breakfast "
United States
Jessica
The price is 1.900.681 ₫
2.147.770 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Ramada by Wyndham Sellersburg/Louisville North
Suite, 1 King Bed, Non Smoking | In-room safe, desk, iron/ironing board, free cots/infant beds
Comfort Inn & Suites Louisville Airport Fair & Expo

Comfort Inn & Suites Louisville Airport Fair & Expo

Comfort Inn & Suites Louisville Airport Fair & Expo
2.5 star property
Fairgrounds, 7 km from Cherokee Seneca
8.4 out of 10, Very good, (137)
"Room was large and clean. The beds were comfortable and the staff friendly and accommodating. The breakfast was good also. Will definitely come back!"
United States
Marina
The price is 2.278.512 ₫
2.644.669 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Comfort Inn & Suites Louisville Airport Fair & Expo
Exterior
La Quinta Inn & Suites by Wyndham Louisville NE/Old Henry Rd

La Quinta Inn & Suites by Wyndham Louisville NE/Old Henry Rd

La Quinta Inn & Suites by Wyndham Louisville NE/Old Henry Rd
3.0 star property
17.2 km from Cherokee Seneca
8.4 out of 10, Very good, (918)
"Room was very clean. Staff were nice. "
United States
Cazza
The price is 2.062.469 ₫
2.426.701 ₫ total
includes taxes & fees
9 Jan - 10 Jan 2026
La Quinta Inn & Suites by Wyndham Louisville NE/Old Henry Rd
Exterior
Holiday Inn Louisville Airport South by IHG

Holiday Inn Louisville Airport South by IHG

Holiday Inn Louisville Airport South by IHG
3.0 star property
9.5 km from Cherokee Seneca
8.8 out of 10, Excellent, (780)
"The staff was amazing and so helpful, the breakfast was amazing and the rooms were clean and beds were comfy! "
Canada
Alexandra mari
The price is 2.183.481 ₫
2.569.084 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Holiday Inn Louisville Airport South by IHG
Lobby
Best Western Louisville Airport Expo

Best Western Louisville Airport Expo

Best Western Louisville Airport Expo
2.5 star property
6.2 km from Cherokee Seneca
8.6 out of 10, Excellent, (1002)
"Ecxellent hotel, will definitely stay again"
United States
Demchigsuren
The price is 2.083.777 ₫
2.451.772 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Best Western Louisville Airport Expo
Exterior
Hilton Garden Inn Jeffersonville Louisville North

Hilton Garden Inn Jeffersonville Louisville North

Hilton Garden Inn Jeffersonville Louisville North
3.0 star property
12.2 km from Cherokee Seneca
9.6 out of 10, Exceptional, (403)
"The staff was very friendly and helpful. The facility was clean, safe and well maintained. "
United States
Bianca
The price is 2.714.882 ₫
3.067.817 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Hilton Garden Inn Jeffersonville Louisville North
Exterior
Hilton Garden Inn Louisville Airport

Hilton Garden Inn Louisville Airport

Hilton Garden Inn Louisville Airport
3.0 star property
Fairgrounds, 6.9 km from Cherokee Seneca
9.0 out of 10, Wonderful, (1001)
"All areas of the hotel, inside and out were spotless. Staff were very friendly. Breakfast for two was around $35."
United States
Martha
The price is 2.286.674 ₫
2.690.501 ₫ total
includes taxes & fees
26 Dec - 27 Dec
Hilton Garden Inn Louisville Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Cherokee Seneca

Find the best Cherokee Seneca areas for the activities you enjoy most.
Louisville showing street scenes and signage as well as a small group of people

Downtown Louisville

Downtown Louisville is beloved for its fantastic nightlife. Take some time to explore sights in the area like Whiskey Row and KFC Yum Center.

Fairgrounds

While visiting Fairgrounds, you might make a stop by sights like Freedom Hall and Kentucky Kingdom.

Jeffersontown

Jeffersontown is known for its abundant dining options, and you can plan a trip to Bluegrass Indoor Karting and Jeffersontown Commons Shopping Center while you're in town.

St. Matthews

St. Matthews is noteworthy for its shopping, and you can make a stop at top attractions like Mall St. Matthews and Saint Matthews Pavilion Shopping Center.

Conrad Caldwell House showing signage and heritage elements

Old Louisville

Old Louisville is known for its ample dining options, and you can make a stop by Ohio River Valley and Conrad-Caldwell House Museum while in the area.

Top Cherokee Seneca Hotel Reviews

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Frequently asked questions

What is Cherokee Seneca like?
You'll be sure to have fun exploring Louisville's Cherokee Seneca neighbourhood.
If I need to cancel my hotel reservation in Cherokee Seneca, will I receive a refund?
Yes, you'll find most room reservations are fully refundable provided that you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you might still have the option to cancel and be given a refund within 24 hours of booking. Add your dates and click on "Search", then you can use the "fully refundable" filter to review the best deals in Cherokee Seneca.
What is there to do around this Louisville neighbourhood?
Peterson-Dumesnil House, Historic Frankfort Avenue and Colonel Sanders' Grave are just a few of the places to visit in and around Cherokee Seneca. Muhammad Ali Gravesite and Mid City Mall Shopping Center are also worth a visit when you're out sightseeing in Louisville.