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Our top choices for Crescent Medical Center Lancaster hotels

Exterior
Fairfield by Marriott Inn & Suites DeSoto Dallas South

Fairfield by Marriott Inn & Suites DeSoto Dallas South

Fairfield by Marriott Inn & Suites DeSoto Dallas South
2.5 star property
2.3 km from Crescent Medical Center Lancaster
9.4 out of 10, Exceptional, (224)
"Clean facility, nice staff"
United States
Laketa
The price is 2.736.864 ₫
3.092.656 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Fairfield by Marriott Inn & Suites DeSoto Dallas South
Lobby
La Quinta Inn & Suites by Wyndham DeSoto

La Quinta Inn & Suites by Wyndham DeSoto

La Quinta Inn & Suites by Wyndham DeSoto
3.0 star property
2.6 km from Crescent Medical Center Lancaster
9.0 out of 10, Wonderful, (162)
"Excellent service, great room for the price, and nice staff. "
United States
Anna
The price is 2.484.330 ₫
2.938.948 ₫ total
includes taxes & fees
28 Dec - 29 Dec
La Quinta Inn & Suites by Wyndham DeSoto
Exterior
Red Roof Inn Lancaster, TX

Red Roof Inn Lancaster, TX

Red Roof Inn Lancaster, TX
2.0 star property
2 km from Crescent Medical Center Lancaster
8.8 out of 10, Excellent, (430)
"My stay was very nice. The room was spacious & the bed was comfortable. The front desk staff and check in was easy as well."
United States
Courtanay
The price is 2.079.886 ₫
2.350.305 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Red Roof Inn Lancaster, TX
Pool
GLō Best Western Dallas South DeSoto

GLō Best Western Dallas South DeSoto

GLō Best Western Dallas South DeSoto
3.0 star property
1.4 km from Crescent Medical Center Lancaster
8.6 out of 10, Excellent, (1000)
"Just a great hotel at a great price. "
United States
Tony
The price is 2.044.490 ₫
2.310.275 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
GLō Best Western Dallas South DeSoto
Seasonal outdoor pool
Hawthorn Extended Stay by Wyndham DeSoto

Hawthorn Extended Stay by Wyndham DeSoto

Hawthorn Extended Stay by Wyndham DeSoto
2.5 star property
2.7 km from Crescent Medical Center Lancaster
8.8 out of 10, Excellent, (52)
"Very clean, very nice staff and no issues Highly recommended "
United States
Terrah
The price is 3.080.727 ₫
3.481.222 ₫ total
includes taxes & fees
18 Jan - 19 Jan 2026
Hawthorn Extended Stay by Wyndham DeSoto
Exterior
Holiday Inn Express Hotel & Suites Dallas South - Desoto by IHG

Holiday Inn Express Hotel & Suites Dallas South - Desoto by IHG

Holiday Inn Express Hotel & Suites Dallas South - Desoto by IHG
2.5 star property
2.1 km from Crescent Medical Center Lancaster
8.6 out of 10, Excellent, (923)
"I only stayed one night but slept beautifully "
United States
Ashana
The price is 3.107.058 ₫
3.510.976 ₫ total
includes taxes & fees
29 Dec - 30 Dec
Holiday Inn Express Hotel & Suites Dallas South - Desoto by IHG
Property amenity
Comfort Suites DeSoto Dallas South

Comfort Suites DeSoto Dallas South

Comfort Suites DeSoto Dallas South
2.5 star property
2.3 km from Crescent Medical Center Lancaster
8.4 out of 10, Very good, (1000)
"Room was spotless, great breakfast nice friendly staff and the place smells so fresh and clean "
United States
Rosetta
The price is 2.418.440 ₫
2.732.653 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Comfort Suites DeSoto Dallas South
Free daily buffet breakfast
Hampton Inn & Suites Dallas-DeSoto

Hampton Inn & Suites Dallas-DeSoto

Hampton Inn & Suites Dallas-DeSoto
2.5 star property
2.8 km from Crescent Medical Center Lancaster
8.4 out of 10, Very good, (851)
"Great stay! Room was awesome!! "
United States
Karren
The price is 2.567.915 ₫
2.901.744 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Hampton Inn & Suites Dallas-DeSoto
Terrace/patio
Home2 Suites by Hilton Dallas DeSoto

Home2 Suites by Hilton Dallas DeSoto

Home2 Suites by Hilton Dallas DeSoto
3.0 star property
2.8 km from Crescent Medical Center Lancaster
8.4 out of 10, Very good, (252)
"It was good "
United States
Vincent
The price is 3.118.380 ₫
3.523.770 ₫ total
includes taxes & fees
18 Jan - 19 Jan 2026
Home2 Suites by Hilton Dallas DeSoto
Exterior
Motel 6 Lancaster, TX - DeSoto - Lancaster

Motel 6 Lancaster, TX - DeSoto - Lancaster

Motel 6 Lancaster, TX - DeSoto - Lancaster
2.0 star property
1.2 km from Crescent Medical Center Lancaster
7.0 out of 10, Good, (949)
"The staff is very polite, it is pet friendly, and the kitchenette room is exactly what we needed for our length of stay"
United States
Tamara
The price is 1.710.277 ₫
1.932.647 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Motel 6 Lancaster, TX - DeSoto - Lancaster
Lobby
Days Inn & Suites by Wyndham DeSoto

Days Inn & Suites by Wyndham DeSoto

Days Inn & Suites by Wyndham DeSoto
2.0 star property
1.9 km from Crescent Medical Center Lancaster
6.8 out of 10, (1000)
"Very nice staff and accommodating room"
United States
Ronald
The price is 2.078.964 ₫
2.349.229 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Days Inn & Suites by Wyndham DeSoto
Restaurant
Red Roof Inn Lancaster, Tx

Red Roof Inn Lancaster, Tx

Red Roof Inn Lancaster, Tx
2 km from Crescent Medical Center Lancaster
Red Roof Inn Lancaster, Tx
Seasonal outdoor pool
La Quinta Inn & Suites by Wyndham-Red Oak TX IH-35E

La Quinta Inn & Suites by Wyndham-Red Oak TX IH-35E

La Quinta Inn & Suites by Wyndham-Red Oak TX IH-35E
3.0 star property
8 km from Crescent Medical Center Lancaster
9.2 out of 10, Wonderful, (904)
"Room and whole hotel was clean. Seems to be a safe area. Only drawback is the road construction in the area causing delays in driving. Would stay again."
United States
Robert
The price is 2.725.022 ₫
3.079.275 ₫ total
includes taxes & fees
28 Dec - 29 Dec
La Quinta Inn & Suites by Wyndham-Red Oak TX IH-35E
Lobby sitting area
Best Western Plus Duncanville/Dallas

Best Western Plus Duncanville/Dallas

Best Western Plus Duncanville/Dallas
2.5 star property
8.4 km from Crescent Medical Center Lancaster
8.8 out of 10, Excellent, (955)
"Cleanliness ……….5 star Front Desk service …..5 star Breakfast…………. Normal hotel breakfast "
United States
Bernetta
The price is 2.028.437 ₫
2.292.134 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Best Western Plus Duncanville/Dallas
Exterior
Hampton Inn & Suites Duncanville Dallas

Hampton Inn & Suites Duncanville Dallas

Hampton Inn & Suites Duncanville Dallas
2.5 star property
10.9 km from Crescent Medical Center Lancaster
9.2 out of 10, Wonderful, (812)
"The hot breakfast was good. Our room was spotless and the bed was comfortable. I liked that it was a good location for off and on the freeway "
United States
Maricela
The price is 2.326.334 ₫
2.642.704 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Hampton Inn & Suites Duncanville Dallas
Lobby
Sleep Inn Lancaster Dallas South

Sleep Inn Lancaster Dallas South

Sleep Inn Lancaster Dallas South
2.5 star property
3.5 km from Crescent Medical Center Lancaster
7.8 out of 10, Good, (490)
"Great room "
United States
Joanna
The price is 2.337.650 ₫
2.641.544 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Sleep Inn Lancaster Dallas South
Suite, 1 King Bed with Sofa bed, Accessible, Non Smoking (Accessible Tub) | Pillow-top beds, desk, iron/ironing board, free WiFi
MainStay Suites Lancaster Dallas South

MainStay Suites Lancaster Dallas South

MainStay Suites Lancaster Dallas South
2.5 star property
3.5 km from Crescent Medical Center Lancaster
7.8 out of 10, Good, (230)
"The breakfast is good , the pool was always clean "
United States
Kristin
The price is 2.936.602 ₫
3.318.360 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
MainStay Suites Lancaster Dallas South
Exterior
Holiday Inn Express Hotel & Suites Dallas - Duncanville by IHG

Holiday Inn Express Hotel & Suites Dallas - Duncanville by IHG

Holiday Inn Express Hotel & Suites Dallas - Duncanville by IHG
2.5 star property
8.5 km from Crescent Medical Center Lancaster
8.6 out of 10, Excellent, (1003)
"I had the best experience here and will be coming back!"
United States
Victoria
The price is 2.552.652 ₫
2.937.129 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Holiday Inn Express Hotel & Suites Dallas - Duncanville by IHG
BBQ/picnic Area
TownePlace Suites Dallas DeSoto

TownePlace Suites Dallas DeSoto

TownePlace Suites Dallas DeSoto
3.0 star property
8.3 km from Crescent Medical Center Lancaster
8.4 out of 10, Very good, (622)
"Good breakfast variety. Clean room. Friendly staff"
United States
Nain
The price is 2.832.654 ₫
3.200.899 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
TownePlace Suites Dallas DeSoto
Lobby
Fairfield Inn & Suites by Marriott Dallas Cedar Hill

Fairfield Inn & Suites by Marriott Dallas Cedar Hill

Fairfield Inn & Suites by Marriott Dallas Cedar Hill
2.5 star property
12.2 km from Crescent Medical Center Lancaster
9.0 out of 10, Wonderful, (526)
"Had a great short stay for a business trip. Friendly staff, spacious and quiet room, clean. "
United States
Matteson
The price is 2.184.228 ₫
2.468.177 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Fairfield Inn & Suites by Marriott Dallas Cedar Hill
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Crescent Medical Center Lancaster Hotel Reviews

Fairfield by Marriott Inn & Suites DeSoto Dallas South

Fairfield by Marriott Inn & Suites DeSoto Dallas South

10/10 Excellent
"Room was very tidy and elegant. Staff were extremely courteous and helpful. "
Sakala Mohan R 1-night trip
Posted 1 day ago
Fairfield by Marriott Inn & Suites DeSoto Dallas South

Hotels near other Crescent Medical Center Lancaster attractions

Lancaster Plaza

You can search for that perfect souvenir at Lancaster Plaza during your trip to Lancaster. Discover the area's festivals and shops.
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Cinemark Lancaster Movies 14

You can take time to visit Cinemark Lancaster Movies 14 during your travels to Lancaster. Discover the area's festivals and shops.
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Frequently asked questions

What's the area like around Crescent Medical Center Lancaster?
Crescent Medical Center Lancaster is located in Lancaster. If you're looking for a convenient place to stay, take a look at the 11 hotels and other accommodation options you'll find within a mile.
How many hotels are there close to Crescent Medical Center Lancaster?
Expedia has 11 hotels and other accommodation options within a mile from Crescent Medical Center Lancaster.
If I need to cancel the hotel reservation for my stay near Crescent Medical Center Lancaster, will I receive a refund?
Yes! Most hotel reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which is often 24 or 48 hours before your arrival date. If you have a non-refundable reservation, you might be able to cancel it and get a refund within 24 hours of booking. Add dates, click "Search", then you can use the "fully refundable" filter to view the best deals available near Crescent Medical Center Lancaster.
What can I see and do near Crescent Medical Center Lancaster?
You might spend a leisurely day outdoors at Curtistene S. McCowan Park and Alta Mesa Park. If you're looking forward to a day of shopping, consider Blue Grove Plaza, Lancaster Plaza and Travel Centers of America - Dallas South and pick out the perfect souvenir. If you have some time to wander around the area, you might stop by Cinemark Lancaster Movies 14, Tiger Field or AMF DeSoto Lanes.