A wooden dock extending into a calm lake surrounded by trees.

Find the best Alexander County Hotels

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Alexander County Accommodation: Most Popular Cities to Stay

A steel bridge with a sunset in the background.
HotelsHotels

Cairo

Cairo

Check prices for these dates

This weekend
30 Oct - 1 Nov
Next weekend
6 Nov - 8 Nov

Filter by

Property class

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Our top choices for Alexander County hotels

A hotel lobby with a reception desk, seating area, and a large window.

1. Quality Inn Cairo I-57

Quality Inn Cairo I-57
2.5 star property
Cairo
6.4 out of 10, (296 reviews)
"Good service,nice stuff and no complaints"
United States
Santiago
The price is 1.779.497 ₫
1.974.886 ₫ total
includes taxes & fees
15 Nov - 16 Nov
Quality Inn Cairo I-57
A building with a fountain and flower beds in front.

2. The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston
2.5 star property
Charleston
6.8 out of 10, (443 reviews)
"Everything was great clean helpful Everything friendly."
United States
Kathleen
The price is 1.718.168 ₫
1.923.604 ₫ total
includes taxes & fees
29 Oct - 30 Oct
The Riverstone Hotel Charleston-Sikeston
A hotel room with a large bed, two bedside lamps, a framed picture of a bridge, and a wooden nightstand with a phone.

3. Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
Charleston
6.8 out of 10, (680 reviews)
"Breakfast was light but good"
United States
zandra
The price is 1.537.539 ₫
1.721.659 ₫ total
includes taxes & fees
28 Oct - 29 Oct
Super 8 by Wyndham Charleston/Sikeston East MO
A hotel room with a large bed, a desk, a television, and a bathroom visible through an open door.

4. Eagle Inn Charleston

Eagle Inn Charleston
2.0 star property
Charleston
6.6 out of 10, (107 reviews)
"Great"
United States
Jackson
The price is 1.705.248 ₫
1.909.392 ₫ total
includes taxes & fees
28 Oct - 29 Oct
Eagle Inn Charleston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Alexander County Hotel Reviews

Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

10/10 Excellent
"Clean, spacious suite, enjoyable kick back and breakfast!"
Mary 1-night trip
Posted 11 hours ago
Drury Inn & Suites Cape Girardeau