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Check availability on Downtown Cincinnati Spa Hotels

Our top choices for Downtown Cincinnati hotels with a spa

Body treatments, hydrotherapy, hot stone massages, deep-tissue massages
21c Museum Hotel Cincinnati

21c Museum Hotel Cincinnati

21c Museum Hotel Cincinnati
4.5 star property
Downtown Cincinnati
8.6 out of 10, Excellent, (1007)
"Very clean rooms, great bar, friendly staff."
United States
Theodore
The price is 3.788.051 ₫
4.650.994 ₫ total
includes taxes & fees
2 Jan - 3 Jan 2026
21c Museum Hotel Cincinnati
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Downtown Cincinnati Hotel Reviews

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Frequently asked questions

Looking for a spa hotel in Downtown Cincinnati?
Forget the stress of everyday life and book yourself a hotel with a spa. Travellers highly recommend the restaurants in Downtown Cincinnati. Take in the culture at the museums and art galleries during your stay. Hotels with spas are the perfect way to take a break from your daily routine and add a layer of luxury to your stay.
How many spa hotels will I find in Downtown Cincinnati?
Among Expedia's 372 accommodation options in Downtown Cincinnati, there is 1 spa hotel.
What's there to see and do in Downtown Cincinnati?
Enjoy Downtown Cincinnati and visit Fountain Square, Paycor Stadium and National Underground Railroad Freedom Center. If you have extra time while you're in the area, you might want to stop by The Andrew J Brady Music Center and Aronoff Center for the Arts.
What is a Downtown Cincinnati spa hotel?
Spa hotels in Downtown Cincinnati provide lodging and have an on-site spa offering services such as therapies as well as beauty treatments. Some also offer in-room treatments. Spa hotels are a must if you want to give yourself an extra treat while on holiday.