Photo by Samantha Baker

Search Hotels in Downtown Trempealeau, Trempealeau

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
9 Dec - 10 Dec
Tomorrow
10 Dec - 11 Dec
This weekend
12 Dec - 14 Dec
Next weekend
19 Dec - 21 Dec

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Downtown Trempealeau hotels

Terrace/patio
Little Bluff Inn

Little Bluff Inn

2.5 star property
Downtown Trempealeau
10.0 out of 10, Exceptional, (110)
"Clean room, nice beds, hot shower and great hospitality!"
United States
Joe
Little Bluff Inn
Exterior
AmericInn by Wyndham Winona

AmericInn by Wyndham Winona

2.5 star property
20.8 km from Downtown Trempealeau
9.0 out of 10, Wonderful, (892)
"Nice time with clean accomodations and friendly staff. Will stay there again. "
United States
JEANETTE
The price is 2.823.370 ₫
3.151.585 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
AmericInn by Wyndham Winona
Free buffet breakfast
Holiday Inn Express & Suites Winona by IHG

Holiday Inn Express & Suites Winona by IHG

2.5 star property
14.9 km from Downtown Trempealeau
9.2 out of 10, Wonderful, (894)
"Clean room, nice staff, good breakfast"
United States
Brenda
The price is 2.741.648 ₫
3.060.364 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Holiday Inn Express & Suites Winona by IHG
Lobby
Days Inn by Wyndham Winona

Days Inn by Wyndham Winona

2.0 star property
21.1 km from Downtown Trempealeau
7.8 out of 10, Good, (1003)
"Comfortable bed."
United States
Bridget
The price is 1.523.724 ₫
1.700.857 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Days Inn by Wyndham Winona
Dining
Super 8 by Wyndham Winona MN

Super 8 by Wyndham Winona MN

2.0 star property
15.1 km from Downtown Trempealeau
7.6 out of 10, Good, (1002)
"Clean rooms, friendly & courteous staff, convenient to many stores, reasonable rates. "
United States
Nicole
The price is 1.370.824 ₫
1.557.598 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Super 8 by Wyndham Winona MN
Lunch and dinner served, American cuisine
The Plaza Hotel & Suites Winona

The Plaza Hotel & Suites Winona

3.0 star property
14.8 km from Downtown Trempealeau
8.8 out of 10, Excellent, (1004)
"The pools were great"
United States
Beth
The price is 3.163.440 ₫
3.531.190 ₫ total
includes taxes & fees
10 Dec - 11 Dec
The Plaza Hotel & Suites Winona
Property amenity
Fairfield Inn & Suites by Marriott Winona

Fairfield Inn & Suites by Marriott Winona

2.5 star property
14.9 km from Downtown Trempealeau
9.4 out of 10, Exceptional, (360)
"I have been to this hotel several times and I am never disappointed."
United States
Marla
The price is 2.823.370 ₫
3.151.588 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Fairfield Inn & Suites by Marriott Winona
Miscellaneous
Alexander Mansion Bed and Breakfast

Alexander Mansion Bed and Breakfast

3.5 star property
16.3 km from Downtown Trempealeau
9.8 out of 10, Exceptional, (486)
"The breakfast was wonderful"
United States
Marlin
Alexander Mansion Bed and Breakfast
Indoor spa tub
Stoney Creek Hotel La Crosse - Onalaska

Stoney Creek Hotel La Crosse - Onalaska

2.5 star property
24.8 km from Downtown Trempealeau
9.0 out of 10, Wonderful, (1586)
"room was clean staff was great"
United States
Marc
The price is 2.601.402 ₫
2.952.280 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Stoney Creek Hotel La Crosse - Onalaska
Indoor pool
GrandStay Hotel & Suites

GrandStay Hotel & Suites

2.5 star property
25.6 km from Downtown Trempealeau
9.0 out of 10, Wonderful, (1036)
"Amazing place"
United States
Tim
The price is 2.752.193 ₫
3.165.023 ₫ total
includes taxes & fees
10 Dec - 11 Dec
GrandStay Hotel & Suites
Hypo-allergenic bedding, desk, iron/ironing board, free WiFi
Country Inn & Suites by Radisson, La Crosse, WI

Country Inn & Suites by Radisson, La Crosse, WI

2.5 star property
22.8 km from Downtown Trempealeau
8.8 out of 10, Excellent, (1001)
"The room and pool area were clean staff was friendly and helpful "
United States
Stephanie
The price is 1.665.815 ₫
1.915.687 ₫ total
includes taxes & fees
8 Jan - 9 Jan 2026
Country Inn & Suites by Radisson, La Crosse, WI
Exterior detail
Radisson Hotel La Crosse

Radisson Hotel La Crosse

3.5 star property
25.8 km from Downtown Trempealeau
8.6 out of 10, Excellent, (1005)
"The room was clean and the staff was courteous."
United States
Beverly
The price is 2.823.370 ₫
3.247.007 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Radisson Hotel La Crosse
Free continental breakfast
Holiday Inn Express & Suites Onalaska La Crosse Area by IHG

Holiday Inn Express & Suites Onalaska La Crosse Area by IHG

2.5 star property
24 km from Downtown Trempealeau
9.2 out of 10, Wonderful, (499)
"Best breakfast ever!"
United States
Erin
The price is 2.293.494 ₫
2.603.116 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Holiday Inn Express & Suites Onalaska La Crosse Area by IHG
Property amenity
Courtyard by Marriott La Crosse

Courtyard by Marriott La Crosse

3.0 star property
26.1 km from Downtown Trempealeau
9.0 out of 10, Wonderful, (537)
"Very comfortable bed in the room was spotless! We used the fitness center and that was also very nice and clean."
United States
Melissa
The price is 3.110.716 ₫
3.577.323 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Courtyard by Marriott La Crosse
Front of property
Spark by Hilton La Crosse Onalaska

Spark by Hilton La Crosse Onalaska

2.5 star property
24.5 km from Downtown Trempealeau
8.4 out of 10, Very good, (84)
"The staff was extremely helpful and courteous. The room was comfortable with a large shower area. I would definitely stay here agin"
United States
Kevin
The price is 1.876.974 ₫
2.175.181 ₫ total
includes taxes & fees
19 Dec - 20 Dec
Spark by Hilton La Crosse Onalaska
Indoor pool, pool loungers
Gundersen Hotel & Suites

Gundersen Hotel & Suites

2.5 star property
27.7 km from Downtown Trempealeau
9.4 out of 10, Exceptional, (1000)
"The breakfast had a simple but good selection. Clean, quiet and conveniently located by the hospital. "
United States
Rhonda
Gundersen Hotel & Suites
Lobby
Express Suites Riverport Inn & Suites

Express Suites Riverport Inn & Suites

3.0 star property
15 km from Downtown Trempealeau
8.6 out of 10, Excellent, (1001)
"Room was clean staff was frendly and helpfull"
United States
Glenda
The price is 2.609.574 ₫
2.913.001 ₫ total
includes taxes & fees
10 Dec - 11 Dec
Express Suites Riverport Inn & Suites
Classic Double Room | Individually decorated, individually furnished, desk, iron/ironing board
Prairie Inn and Suites Holmen/La Cross

Prairie Inn and Suites Holmen/La Cross

2.0 star property
17.9 km from Downtown Trempealeau
9.0 out of 10, Wonderful, (783)
"The hotel is great...clean and quiet. Breakfast was good and the staff are very friendly!"
United States
Chad
The price is 1.446.483 ₫
1.598.065 ₫ total
includes taxes & fees
11 Dec - 12 Dec
Prairie Inn and Suites Holmen/La Cross
Lunch and dinner served
Best Western Plus LaCrescent / LaCrosse

Best Western Plus LaCrescent / LaCrosse

2.5 star property
21.9 km from Downtown Trempealeau
9.2 out of 10, Wonderful, (504)
"Clean, modern, breakfast, swing bridge pub - excellent"
United States
Susan
The price is 2.586.376 ₫
2.893.507 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Best Western Plus LaCrescent / LaCrosse
Lobby
Quality Inn La Crosse North

Quality Inn La Crosse North

2.5 star property
23 km from Downtown Trempealeau
8.0 out of 10, Very good, (1002)
"Great place to stay"
United States
Dave
The price is 1.565.903 ₫
1.800.788 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Quality Inn La Crosse North
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Downtown Trempealeau Hotel Reviews

Explore a world of travel with Expedia

Frequently asked questions

What is Downtown Trempealeau like?
Travellers to Trempealeau's Downtown Trempealeau neighbourhood will be sure to enjoy a stay here. Consider a visit to Mississippi River as part of your Downtown Trempealeau travel plans.
How many hotels will I find in Downtown Trempealeau?
Expedia has 5 Downtown Trempealeau hotels and other accommodation options, and one might make a good home base for venturing out into the greater Trempealeau area.
If I need to cancel my hotel reservation in Downtown Trempealeau, will I receive a refund?
Yes! The majority of hotel bookings are refundable provided that you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before your check-in date. If your reservation is non-refundable, you might still have the option to cancel and be given a refund within a 24-hour period of booking. Put your dates in and click on "Search", then you can filter by "fully refundable" to view top deals in Downtown Trempealeau.
What is there to do around this Trempealeau neighbourhood?
Mississippi River is an attraction you might want to check out while you're in Downtown Trempealeau. While you're out sightseeing, Perrot State Park and Trempealeau Moutain Golf Club are a couple of additional sights to visit in Trempealeau.