East Seneca Holidays

Book a Hotel + Flight or Car together to unlock savings

Where to stay in East Seneca

Find the best East Seneca areas and neighborhoods for the activities you enjoy most. Learn more about East Seneca
Buffalo which includes a monument, a skyscraper and a city

Downtown Buffalo

4 out of top 10 points of interest in this area
4.5/5(10 area reviews)

Known for its great bars and great live music, there's plenty to explore in Downtown Buffalo. You can visit top attractions like Chippewa District and Statler Tower, and jump on the metro at Fountain Plaza Station or Lafayette Square Station to see more of the city.

Find hotels in Downtown Buffalo

Top hotels in East Seneca

M Hotel Buffalo

M Hotel Buffalo

3.5 out of 5
2040 Walden Ave, Buffalo, NY
Fully refundableReserve now, pay when you stay
The price is 2.594.568 ₫ per night from 17 Aug to 18 Aug
2.594.568 ₫
2.951.436 ₫ total
17 Aug - 18 Aug
includes taxes & fees
7.2/10 Good! (1,895 reviews)
A little warm & in need of some upgrades
"Super reasonably priced. Bed was comfy enough. We were on the 6th floor and even though the AC was set to 60, it definitely was NOT 60 in our room. The shower definitely needs an upgrade. Very old & little to no water pressure."

Reviewed on 8 Aug 2025

M Hotel Buffalo
Hyatt Regency Buffalo / Hotel and Conference Center

Hyatt Regency Buffalo / Hotel and Conference Center

3.5 out of 5
Two Fountain Plaza, Buffalo, NY
Fully refundableReserve now, pay when you stay
The price is 2.989.257 ₫ per night from 1 Sept to 2 Sept
2.989.257 ₫
3.400.278 ₫ total
1 Sept - 2 Sept
includes taxes & fees
7.8/10 Good! (1,478 reviews)
"Top quality"

Reviewed on 12 Aug 2025

Hyatt Regency Buffalo / Hotel and Conference Center
Buffalo Airport Hotel

Buffalo Airport Hotel

3 out of 5
4600 Genesee St, Buffalo, NY
Fully refundableReserve now, pay when you stay
The price is 2.115.308 ₫ per night from 13 Aug to 14 Aug
2.115.308 ₫
2.406.162 ₫ total
13 Aug - 14 Aug
includes taxes & fees
7.8/10 Good! (2,602 reviews)
"Good staff Good spacious room Right next to airport Need car to move around for food Onlybuffalo wings next to hotel."

Reviewed on 11 Aug 2025

Buffalo Airport Hotel
See all 754 properties in East Seneca
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does an East Seneca holiday package cost?
Get set to book, because a trip to East Seneca starts from an enticing . When you bundle your hotels, flights and car rentals into a holiday package, you'll enjoy the biggest bargains.
How do I get a cheap travel package to East Seneca?
Combine your hotels and flights, add on extras such as activities or a rental car, and save with an East Seneca holiday package. You won't just score exciting discounts on your escape — you'll have loads of choice at your fingertips too. When you book with Expedia, you'll have your pick of over 550 air carriers and 1null000null000 properties worldwide. Your next big adventure starts right here, right now!
Where should I stay in East Seneca?
With popular attractions like Southgate Plaza and Charles E. Burchfield Nature and Art Centre in this neighbourhood, look for a hotel situated near either of them. Enjoy The Journey Art Gallery is another East Seneca sight that visitors flock to.
How far in advance should I book my East Seneca holiday?
While prices fluctuate, we generally recommend booking your flight as soon as possible. Most international airfares can be compared on Expedia up to a year in advance. If circumstances have left you booking late, you might still get lucky. Cheap tickets to East Seneca sometimes occur just weeks before departure.
What does an Expedia East Seneca travel package include?
Much of that depends on you. You can choose from a variety of East Seneca packages, such as a hotel, rental car and flight. You can also book a hotel with a flight, or a rental car and a flight. Once you've made your booking, you can add on the fun stuff like experiences and tours. Whatever your ideal East Seneca trip looks like, get ready to save!
What should I know before booking an East Seneca travel package?
You'll save big with an Expedia travel package. Bundle your airfares, rental cars and hotels and unlock terrific discounts. Hotels aren't your only option, though. We have island villas, mountain cabins and even glamping tents!
Can I choose my airline with an East Seneca Expedia holiday package?
Expedia offers access to more than 550 airline partners worldwide, so you certainly can. Just pick your preferred air carrier and create the perfect East Seneca trip.
If I'm not able to travel, can I cancel my East Seneca holiday package?
Whether it's your flight or hotel, yes, you can cancel or amend it. Booked your East Seneca holiday package in the last 24 hours? You may be able to make changes or cancellations for free. For bookings made more than 24 hours ago, you may be charged a fee by your hotel, airline or car rental company. For further information, check out our Customer Service Portal. We're here to help you each step of the way.

Popular places to visit

University At Buffalo - North Campus

University At Buffalo - North Campus

Walk around the campus of University At Buffalo - North Campus, a top university in Amherst. Experience the area's great live music and entertainment choices.

University At Buffalo - North Campus
Buffalo Zoo

Buffalo Zoo

Why not meet the animals who live at Buffalo Zoo during your travels in Buffalo? Experience the area's entertainment choices and acclaimed theatre scene.

Buffalo Zoo
Canisius College

Canisius College

Explore the campus of Canisius College during your trip to Buffalo. Experience the area's great live music and entertainment choices.

Canisius College