Search Boutique Hotels in Florence

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Florence Boutique Hotels

Tonight
4 Dec - 5 Dec
Tomorrow
5 Dec - 6 Dec
This weekend
5 Dec - 7 Dec
Next weekend
12 Dec - 14 Dec

Top Florence Boutique Hotels

No exact matches found, but these alternatives could be just right

Recommended hotels in Florence

Lobby
Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

2.5 star property
Florence
9.2 out of 10, Wonderful, (1157)
"Enjoyed our stay there. "
United States
Cathy
The price is 2.599.520 ₫
2.911.464 ₫ total
includes taxes & fees
7 Dec - 8 Dec
Comfort Inn & Suites Florence Center Area
Exterior
Holiday Inn Express & Suites Latta by IHG

Holiday Inn Express & Suites Latta by IHG

2.5 star property
Latta
9.4 out of 10, Exceptional, (529)
"Clean and beautiful, very friendly staff "
United States
claudia
The price is 2.616.202 ₫
2.851.661 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Holiday Inn Express & Suites Latta by IHG
Exterior
Hampton Inn & Suites Florence-North-I-95

Hampton Inn & Suites Florence-North-I-95

2.5 star property
Florence
9.0 out of 10, Wonderful, (808)
"Clean room, courteous staff and easy access to and from highway."
United States
Joe
The price is 2.721.694 ₫
3.048.298 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Hampton Inn & Suites Florence-North-I-95
Lobby
Howard Johnson by Wyndham Florence

Howard Johnson by Wyndham Florence

2.0 star property
Florence
8.8 out of 10, Excellent, (2470)
"The room was very and the staff was great. "
Canada
Ray
The price is 1.637.763 ₫
1.834.294 ₫ total
includes taxes & fees
8 Dec - 9 Dec
Howard Johnson by Wyndham Florence
Exterior
Park Inn by Radisson Florence, SC

Park Inn by Radisson Florence, SC

2.5 star property
Florence
9.0 out of 10, Wonderful, (2188)
"Friendly and efficient staff and a nice room for my overnight stay."
United States
Carole
The price is 2.479.062 ₫
2.776.549 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Park Inn by Radisson Florence, SC
Terrace/patio
Tru by Hilton Florence I-95

Tru by Hilton Florence I-95

2.5 star property
Florence
8.4 out of 10, Very good, (1000)
"Hotel was clean , friendly staff"
United States
Gabriela
The price is 2.405.218 ₫
2.786.413 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Tru by Hilton Florence I-95
Lobby sitting area
Spark by Hilton Florence North I-95, SC

Spark by Hilton Florence North I-95, SC

2.5 star property
Florence
7.8 out of 10, Good, (21)
"Clean convenient..priced right"
United States
Gloria
The price is 2.405.218 ₫
2.798.017 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Spark by Hilton Florence North I-95, SC
Front of property – evening/night
Hyatt Place Florence Downtown

Hyatt Place Florence Downtown

3.0 star property
Florence
8.8 out of 10, Excellent, (1000)
"Great stay"
United States
Michaelle
The price is 2.637.300 ₫
2.953.776 ₫ total
includes taxes & fees
29 Dec - 30 Dec
Hyatt Place Florence Downtown
Free daily continental breakfast
Fairfield Inn by Marriott Hartsville

Fairfield Inn by Marriott Hartsville

2.5 star property
Hartsville
8.6 out of 10, Excellent, (676)
"Good for overnight stay. Breakfast was a little disappointing….not much variety and hot food was warm at best. Room was very nice. Not familiar with area but hotel is in middle of downtown. "
United States
Lon
The price is 2.219.288 ₫
2.485.601 ₫ total
includes taxes & fees
12 Dec - 13 Dec
Fairfield Inn by Marriott Hartsville
Exterior
Staybridge Suites Florence - Civic Center by IHG

Staybridge Suites Florence - Civic Center by IHG

3.0 star property
Florence
9.4 out of 10, Exceptional, (920)
"Friendly staff, great breakfast, beautiful ammenities!"
United States
Brandi
The price is 2.827.400 ₫
3.166.689 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Staybridge Suites Florence - Civic Center by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Florence Hotel Reviews

Explore a world of travel with Expedia

Frequently asked questions

What's there to see and do in Florence?
The shopping and restaurants are just some of the things to enjoy while you're in the area. Florence Museum, Florence National Cemetery and Dr. Eddie Floyd Tennis Center are some of the local sights worth visiting. While you're here, you might also like to explore more of the area and take in additional sights like Magnolia Mall, Florence Civic Center and Palmetto Shores Lake.
What kind of weather should I plan for when I travel to Florence?
Having a good idea of the weather in Florence will help you enjoy your stay to the fullest. The hottest months are usually July and August, with an average temperature of 26°C, while the coldest months are January and February, with an average of 10°C. Average annual precipitation for Florence is 1366 mm.
What's the best way to get to my boutique hotel in Florence?
You have a few options for getting to and around Florence. The nearest major airport is Florence, SC (FLO-Florence Regional), which is located 2.3 mi (3.7 km) from the heart of the city. If you want to explore the larger area, hop on a train at Florence Station.