Photo by Caroline Nunez

Find hotels in Hartsville, SC from 1.448.647 ₫

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
In two weeks

Filter by

Guest rating
Guest rating
Star rating

Top 10 Hartsville hotels and places to stay

Fairfield Inn by Marriott Hartsville

2.5 star property
Hartsville
8.6 out of 10, Excellent, (676)
"Good for overnight stay. Breakfast was a little disappointing….not much variety and hot food was warm at best. Room was very nice. Not familiar with area but hotel is in middle of downtown. "
United States
Lon
The price is 2.218.446 ₫
2.484.659 ₫ total
includes taxes & fees
13 Dec - 14 Dec
Fairfield Inn by Marriott Hartsville

Hampton Inn & Suites Hartsville

2.5 star property
Hartsville
9.2 out of 10, Wonderful, (478)
"Nice clean hotel. Comfortable beds, nice amenities."
United States
Peggyanne
The price is 3.142.470 ₫
3.519.566 ₫ total
includes taxes & fees
12 Dec - 13 Dec
Hampton Inn & Suites Hartsville

The Landmark Inn

2.5 star property
Hartsville
7.0 out of 10, Good, (312)
"Great staff"
United States
Thomas
The price is 1.898.136 ₫
2.218.183 ₫ total
includes taxes & fees
7 Dec - 8 Dec
The Landmark Inn

The Mantissa Hotel

3.0 star property
Hartsville
9.2 out of 10, Wonderful, (270)
"Very nice spacious rooms friendly staff"
United States
Duane
The price is 4.270.806 ₫
4.783.302 ₫ total
includes taxes & fees
14 Dec - 15 Dec
The Mantissa Hotel

Quality Inn

2.5 star property
Hartsville
6.2 out of 10, (327)
"Lady at desk was plesant and helpful. Sstart3ed to ask for our money back"
United States
Cynthia
The price is 1.657.178 ₫
1.874.757 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Quality Inn

Comfort Inn & Suites Florence Center Area

2.5 star property
Florence
9.2 out of 10, Wonderful, (1158)
"Enjoyed our stay there. "
United States
Cathy
The price is 2.598.337 ₫
2.910.138 ₫ total
includes taxes & fees
8 Dec - 9 Dec
Comfort Inn & Suites Florence Center Area

Hampton Inn & Suites Florence-North-I-95

2.5 star property
Florence
9.0 out of 10, Wonderful, (809)
"Good for an overnight stay "
United States
Allen
The price is 2.805.023 ₫
3.141.679 ₫ total
includes taxes & fees
6 Jan - 7 Jan 2026
Hampton Inn & Suites Florence-North-I-95

Staybridge Suites Florence - Civic Center by IHG

3.0 star property
Florence
9.4 out of 10, Exceptional, (922)
"Friendly staff, great breakfast, beautiful ammenities!"
United States
Brandi
The price is 3.559.005 ₫
3.986.087 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Staybridge Suites Florence - Civic Center by IHG

Park Inn by Radisson Florence, SC

2.5 star property
Florence
9.0 out of 10, Wonderful, (2193)
"Breakfast was great, room very clean ."
United States
Leann
The price is 2.478.122 ₫
2.775.497 ₫ total
includes taxes & fees
7 Dec - 8 Dec
Park Inn by Radisson Florence, SC

Howard Johnson by Wyndham Florence

2.0 star property
Florence
8.8 out of 10, Excellent, (2476)
"I nice place to stay, very quiet, good breakfast, nice staff, spotless room. "
United States
Timothy
The price is 1.637.142 ₫
1.833.599 ₫ total
includes taxes & fees
7 Dec - 8 Dec
Howard Johnson by Wyndham Florence

Days Inn by Wyndham Florence Near Civic Center

2.5 star property
Florence
6.8 out of 10, (1002)
"Clean rooms and wonderful staff "
United States
Rita
The price is 1.634.506 ₫
1.830.647 ₫ total
includes taxes & fees
8 Dec - 9 Dec
Days Inn by Wyndham Florence Near Civic Center

La Quinta Inn & Suites by Wyndham Florence

3.0 star property
Florence
8.0 out of 10, Very good, (1675)
"Th room was nice comfortable breakfast was good and the people were very friendly "
United States
George
The price is 2.704.844 ₫
3.029.426 ₫ total
includes taxes & fees
14 Dec - 15 Dec
La Quinta Inn & Suites by Wyndham Florence

Residence Inn Marriott Florence

3.0 star property
Florence
8.8 out of 10, Excellent, (469)
"Clean rooms and nice size suite area. "
United States
Yolanda
The price is 2.509.758 ₫
2.810.929 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Residence Inn Marriott Florence

Quality Inn & Suites Florence Civic Center

2.5 star property
Florence
7.8 out of 10, Good, (1253)
"Room was spotless, bed extremely comfortable and staff was very helpful and courteous. Would DEFINITELY stay there again. "
United States
Tim
The price is 2.014.660 ₫
2.256.421 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Quality Inn & Suites Florence Civic Center

Fairfield Inn & Suites by Marriott Florence I-20

2.5 star property
Florence
9.0 out of 10, Wonderful, (547)
"Good breakfast and room service "
United States
Indira
The price is 2.826.114 ₫
3.165.247 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Fairfield Inn & Suites by Marriott Florence I-20

Courtyard by Marriott Florence

3.0 star property
Florence
7.8 out of 10, Good, (697)
"Room was good, and the restaurant had amazing drinks and the wings and salad was great. Indoor pool was great "
United States
James H
The price is 2.554.575 ₫
2.861.123 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Courtyard by Marriott Florence

SpringHill Suites by Marriott Florence

3.0 star property
Florence
8.6 out of 10, Excellent, (965)
"Easy check-in. Nice room. "
United States
Tim
The price is 2.792.105 ₫
3.127.158 ₫ total
includes taxes & fees
9 Dec - 10 Dec
SpringHill Suites by Marriott Florence

Springhill Suites by Marriott Cheraw

3.0 star property
Cheraw
9.4 out of 10, Exceptional, (276)
"Great room and hotel. Would definitely recommend and stay again."
United States
Brian
The price is 3.110.834 ₫
3.484.135 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Springhill Suites by Marriott Cheraw

Home2 Suites by Hilton Florence, SC

3.0 star property
Florence
8.2 out of 10, Very good, (1002)
"Clean room, good location, quick checkin"
United States
Brian
The price is 2.720.662 ₫
3.047.140 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Home2 Suites by Hilton Florence, SC

Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG

2.5 star property
Florence
8.6 out of 10, Excellent, (1001)
"Room was clean, staff was courteous and breakfast was great !"
United States
Angela
The price is 3.005.382 ₫
3.366.028 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Holiday Inn Express Hotel & Suites Florence I-95 at Hwy 327 by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Stay near popular Hartsville attractions

Learn more about Hartsville

Stroll along the scenic Black Creek, where kayakers glide past historic buildings and lush parks. Sonoco Park's trails and Kalmia Gardens' blooms offer peaceful retreats, while Coker University's campus adds a vibrant collegiate atmosphere to this charming Southern town.

The Midnight Rooster is my go to spot in my hometown of Hartsville, SC. Great brunch and coffee! Love the courtyard!
Photo by Caroline Nunez
Open Photo by Caroline Nunez

Top Hartsville Hotel Reviews

More cheap stays in Hartsville

Hotels in Hartsville with star rating

Frequently asked questions

What's the seasonal weather like in Hartsville?
The hottest months are usually July and August, with an average temperature of 26°C, while the coldest months are January and February, with an average of 10°C. Average annual precipitation for Hartsville is 1317 mm.

Explore a world of travel with Expedia