Photo by Mark Rentz

Find hotels in Isla Santa María from 1.187.884 ₫

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Check prices for these dates

Tonight
18 Dec - 19 Dec
Tomorrow
19 Dec - 20 Dec
This weekend
19 Dec - 21 Dec
Next weekend
26 Dec - 28 Dec

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Our top choices for Isla Santa María hotels

Terrace/patio
ECO HOSTAL ISLA AZUL

ECO HOSTAL ISLA AZUL

ECO HOSTAL ISLA AZUL
3.0 star property
Puerto Ayora
10.0 out of 10, Exceptional, (2)
"Loved that they had purified water to refill your water bottle instead of buying plastic! Staff were incredibly kind. "
Canada
Jaclyn
The price is 3.713.272 ₫
4.819.510 ₫ total
19 Dec - 20 Dec
ECO HOSTAL ISLA AZUL
Exterior
PENGUIN HOSTEL

PENGUIN HOSTEL

PENGUIN HOSTEL
3.0 star property
Puerto Ayora
The price is 658.275 ₫
1.316.550 ₫ total
18 Jan - 19 Jan 2026
PENGUIN HOSTEL
Exterior
Finch Bay Galapagos Hotel

Finch Bay Galapagos Hotel

Finch Bay Galapagos Hotel
4.5 star property
Puerto Ayora
9.2 out of 10, Wonderful, (87)
"Beautiful resort, impeccably clean, very kind and enthusiastic staff. Delicious restaurant. 5 stars all around, we will definitely return!"
United States
Jonathan
The price is 16.792.200 ₫
18.511.706 ₫ total
16 Jan - 17 Jan 2026
Finch Bay Galapagos Hotel
Restaurant
El Barranco Galapagos

El Barranco Galapagos

El Barranco Galapagos
2.5 star property
Puerto Ayora
9.6 out of 10, Exceptional, (28)
"Incredible place to book your stay in Santa Cruz. Excelent service, rooms and personel. "
United States
Sebastian
The price is 5.570.698 ₫
5.570.698 ₫ total
19 Dec - 20 Dec
El Barranco Galapagos
Front of property
Blu Galapagos Sustainable Waterfront Lodge

Blu Galapagos Sustainable Waterfront Lodge

Blu Galapagos Sustainable Waterfront Lodge
4.0 star property
Puerto Ayora
8.8 out of 10, Excellent, (122)
"Beautiful property "
Canada
David
The price is 5.821.389 ₫
6.403.528 ₫ total
20 Dec - 21 Dec
Blu Galapagos Sustainable Waterfront Lodge
Free daily continental breakfast
Hotel Cucuve

Hotel Cucuve

Hotel Cucuve
4.0 star property
Puerto Ayora
10.0 out of 10, Exceptional, (268)
"Very nice location, friendly staff "
Italy
davide
The price is 5.792.820 ₫
6.372.102 ₫ total
13 Jan - 14 Jan 2026
Hotel Cucuve
Suite, Sea View | Beach/ocean view
Angermeyer Waterfront Inn

Angermeyer Waterfront Inn

Angermeyer Waterfront Inn
3.5 star property
Puerto Ayora
9.4 out of 10, Exceptional, (125)
"More 4 stars for the location, the rooms were ok, beds were extremely firm, we had an issue that was difficult to try and get resolved and never actually was resolved, food at their restaurant was great including the complementary breakfast, very nice that it’s five minutes from an amazing beach and 15 minutes from Las Grietas "
United States
Benjamin
The price is 8.471.924 ₫
9.319.116 ₫ total
19 Dec - 20 Dec
Angermeyer Waterfront Inn
Water view
Twin Hotel Galapagos

Twin Hotel Galapagos

Twin Hotel Galapagos
3.0 star property
Bella Vista
8.4 out of 10, Very good, (44)
"This hotle is fantastic lovely people that work here Very helpful with booking tours ect . To rooms are so fantastic, comfortable bed can’t get any better and good breakfast."
Canada
Chelsea
The price is 3.004.147 ₫
3.004.147 ₫ total
19 Dec - 20 Dec
Twin Hotel Galapagos
Exterior
Mainao

Mainao

Mainao
3.5 star property
Puerto Ayora
9.6 out of 10, Exceptional, (34)
"Great place to stay"
United States
Pavel
Mainao
Exterior
Hotel La Casa de Judy

Hotel La Casa de Judy

Hotel La Casa de Judy
3.0 star property
Puerto Ayora
9.0 out of 10, Wonderful, (160)
"No view from the room, breakfast is so so"
United States
Wai Shan
The price is 1.791.562 ₫
2.186.527 ₫ total
28 Dec - 29 Dec
Hotel La Casa de Judy
Exterior
Capitan Max B&B

Capitan Max B&B

Capitan Max B&B
3.0 star property
Puerto Ayora
9.8 out of 10, Exceptional, (197)
"Good location and the staff was friendly and nice. The room was clean and quiet. "
United States
thuy
Capitan Max B&B
Exterior
Hotel Ninfa

Hotel Ninfa

Hotel Ninfa
3.5 star property
Puerto Ayora
8.4 out of 10, Very good, (217)
"Great, clean, and convenient place. Good location close to docks. Walkable to the Main Street. Hotel rooms clean with good service and breakfast. We stayed here two seperate times during Galapagos and would stay again. "
Canada
Aly
Hotel Ninfa
Free daily buffet breakfast
Ikala Galapagos Hotel

Ikala Galapagos Hotel

Ikala Galapagos Hotel
4.0 star property
Puerto Ayora
9.6 out of 10, Exceptional, (126)
"Nice clean hotel"
United States
Marco
Ikala Galapagos Hotel
Suite, 1 Bedroom | Free minibar, in-room safe, desk, free WiFi
Hotel Santa Fe

Hotel Santa Fe

Hotel Santa Fe
4.0 star property
Puerto Ayora
9.6 out of 10, Exceptional, (14)
"Beautiful hotel, with amazing staff, and great location "
United States
Steven
The price is 4.881.767 ₫
5.369.944 ₫ total
19 Dec - 20 Dec
Hotel Santa Fe
Exterior
Maidith Galapagos Inn

Maidith Galapagos Inn

Maidith Galapagos Inn
3.0 star property
Puerto Ayora
10.0 out of 10, Exceptional, (101)
"Super experience all around. The host and staff were polite and helpful"
United States
Arwen R
The price is 3.317.706 ₫
3.317.706 ₫ total
15 Jan - 16 Jan 2026
Maidith Galapagos Inn
Comfort Quadruple Room | Desk, bed sheets
Grand Hotel Leon Marino Galapagos

Grand Hotel Leon Marino Galapagos

Grand Hotel Leon Marino Galapagos
3.0 star property
Puerto Ayora
8.8 out of 10, Excellent, (13)
"Staff was very friendly and location convenient. Modern interior."
United Kingdom
Marc
The price is 2.432.996 ₫
2.432.996 ₫ total
24 Dec - 25 Dec
Grand Hotel Leon Marino Galapagos
Outdoor pool
Fernandina Hotel & Spa Galápagos

Fernandina Hotel & Spa Galápagos

Fernandina Hotel & Spa Galápagos
3.0 star property
Puerto Ayora
9.4 out of 10, Exceptional, (22)
"Lovely staff and great location "
United States
Lucas
Fernandina Hotel & Spa Galápagos
Outdoor dining
Plaza Luna Suites

Plaza Luna Suites

Plaza Luna Suites
3.0 star property
Puerto Ayora
10.0 out of 10, Exceptional, (34)
"The people were so great, helpful friendly family good vibes, came back a second time already and would stay here next time for sure :)"
Canada
Dustin
Plaza Luna Suites
Family Suite | Balcony view
Posada del Mar

Posada del Mar

Posada del Mar
3.0 star property
Puerto Ayora
9.8 out of 10, Exceptional, (212)
"Well maintained property, front staff was very kind and helpful, and the restaurants beside it were incredible."
Canada
Bianca
The price is 2.156.509 ₫
2.156.509 ₫ total
19 Dec - 20 Dec
Posada del Mar
Family Room, 2 Bedrooms | 1 bedroom, Egyptian cotton sheets, premium bedding, minibar
Hotel el descanso del Guia

Hotel el descanso del Guia

Hotel el descanso del Guia
3.5 star property
Puerto Ayora
8.8 out of 10, Excellent, (174)
"Beautiful and spacious family room. Good breakfast and the staff is courteous. I highly recommend this hotel. "
United States
Susanna
Hotel el descanso del Guia
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Isla Santa María attractions

Swimming with sea turtles was one of the many amazing moments of my Galapagos adventure. Like most of the other animals, they went about their business without seeming to even notice the people around.
Photo by Tove Martin
Open Photo by Tove Martin

Post Office Bay

Commune with nature and explore the great outdoors at Post Office Bay during your travels in Isla Santa María. While you're in the area, wander around the natural setting.
See properties
Bedtime in the Galapagos #golden
Photo by Delen Wong
Open Photo by Delen Wong

Punta Suarez

Explore the great outdoors at Punta Suarez, a lovely green space in Isla Santa María. Wander the seaside and white-sand beaches while you're in the area.
See properties

Learn more about Isla Santa María

Explore attractions like Galápagos National Park and Post Office Bay as you discover things to see and do in Isla Santa María.

See all hotels in Isla Santa María
A greater flamingo searching for dinner. There were a few hundred of them wading in the lagoon.
Photo by Mark Rentz
Open Photo by Mark Rentz

Top Isla Santa María Hotel Reviews

Hotel Fiesta

Hotel Fiesta

10/10 Excellent
"Staff was efficient room was clean "
Jonathan 3-night trip
Posted 5 days ago
Hotel Fiesta

More cheap stays in Isla Santa María

Hostal Casa Cascada

Hostal Casa Cascada

Pje. 1 Puerto Ayora Galápagos Islands
The price is 595.436 ₫ per night from 18 Jan to 19 Jan
595.436 ₫
1.187.884 ₫ total
18 Jan - 19 Jan 2026
9.6/10 Exceptional! (4 reviews)

Frequently asked questions

What's the seasonal weather in Isla Santa María?
The hottest months are usually March and February, with an average temperature of 26°C, while the coldest months are September and October, with an average of 22°C. Average annual precipitation for Isla Santa María is 319 mm.