
Isla Santa María Holidays
Book a Hotel + Flight or Car together to unlock savings
Photo by Delen Wong
Top hotels in Isla Santa María

Hotel Fiesta
Calle Moises Brito y Juan Montalvo Puerto Ayora Galapagos
Fully refundableReserve now, pay when you stay
The price is 4.083.075 ₫ per night from 26 Mar to 27 Mar
4.083.075 ₫
4.083.075 ₫ total
26 Mar - 27 Mar

Maidith Galapagos Inn
Calle Cucuve #341 y Seymour, Santa Cruz Puerto Ayora Galápagos
The price is 3.787.200 ₫ per night from 25 Mar to 26 Mar
3.787.200 ₫
3.787.200 ₫ total
25 Mar - 26 Mar
9.8/10 Exceptional! (120 reviews)
Very helpful staff. The water in the room was very convenient.
Reviewed on 16 Mar 2026

Hotel el descanso del Guia
Calle Delfin, Barrio el Mirador Puerto Ayora Galapagos
8.8/10 Excellent! (194 reviews)
Staff was very helpful. Simple boutique hotel with clean, modern rooms. Wonderful breakfast daily. Highly recommend. Located on the edge of town but only $2 taxi or 20 minute downhill walk to central area of town. Other amenities - assistance with tours, pool, hot tub, bottled water on each floor, ...
Reviewed on 23 Mar 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular places to visit

Post Office Bay
Commune with nature and explore the great outdoors at Post Office Bay during your travels in Isla Santa María. While you're in the area, wander around the natural setting.

Punta Suarez
Explore the great outdoors at Punta Suarez, a lovely green space in Isla Santa María. Wander the seaside and white-sand beaches while you're in the area.
