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14 Dec - 15 Dec
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15 Dec - 16 Dec
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19 Dec - 21 Dec
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26 Dec - 28 Dec

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Our top choices for La Guillotière hotels

Daily buffet breakfast (EUR 13.90 per person)
Ibis Lyon Centre

Ibis Lyon Centre

Ibis Lyon Centre
3.0 star property
La Guillotière
7.8 out of 10, Good, (175)
"nice place to stay "
France
lahouari
The price is 2.171.707 ₫
2.504.384 ₫ total
includes taxes & fees
2 Jan - 3 Jan 2026
Ibis Lyon Centre
Property amenity
Hotel de Noailles

Hotel de Noailles

Hotel de Noailles
3.0 star property
La Guillotière
7.4 out of 10, Good, (115)
"Beautiful property right next to dining and shopping. Highly recommended!"
United States
John
Hotel de Noailles
Breakfast, lunch, dinner served; French cuisine
Ho36 hostels

Ho36 hostels

Ho36 hostels
La Guillotière
8.0 out of 10, Very good, (159)
"Great value hostel, safe comfortable and convenient "
United Kingdom
David
The price is 2.122.349 ₫
2.388.878 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Ho36 hostels
View from property
Fourvière Hôtel Lyon

Fourvière Hôtel Lyon

Fourvière Hôtel Lyon
4.0 star property
Fourvière, 2.8 km from La Guillotière
9.2 out of 10, Wonderful, (1003)
"This property was excellent "
United States
Ed
Fourvière Hôtel Lyon
Exterior
Best Western Hotel Saint Antoine

Best Western Hotel Saint Antoine

Best Western Hotel Saint Antoine
3.0 star property
Les Cordeliers, 1.8 km from La Guillotière
8.2 out of 10, Very good, (434)
"Really great location and helpful staff. Really cramped room, though one of the two the best showers we have had of 20 different hotel rooms on this trip. "
United States
Fred
The price is 1.906.947 ₫
2.213.148 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Best Western Hotel Saint Antoine
Exterior
Campanile PRIME - Lyon Centre Gare Part Dieu

Campanile PRIME - Lyon Centre Gare Part Dieu

Campanile PRIME - Lyon Centre Gare Part Dieu
3.0 star property
1.5 km from La Guillotière
9.0 out of 10, Wonderful, (1197)
"Nice place to stay."
United States
Yuanmei
The price is 2.147.843 ₫
2.478.134 ₫ total
includes taxes & fees
19 Dec - 20 Dec
Campanile PRIME - Lyon Centre Gare Part Dieu
Deluxe Room, River View | 1 bedroom, premium bedding, Select Comfort beds, in-room safe
Le Phenix Hotel

Le Phenix Hotel

Le Phenix Hotel
4.0 star property
Old Lyon, 2.5 km from La Guillotière
9.2 out of 10, Wonderful, (1001)
"Fantastic location with excellent rooms"
United States
Hudson
The price is 3.144.301 ₫
3.635.357 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Le Phenix Hotel
View from property
Hôtel La Résidence Lyon

Hôtel La Résidence Lyon

Hôtel La Résidence Lyon
3.0 star property
Carnot - Gailleton, 1.6 km from La Guillotière
8.4 out of 10, Very good, (1001)
"Ccclean room, nice staff, close to central train station Perrache"
United States
Gerhardus
The price is 2.519.518 ₫
2.887.038 ₫ total
includes taxes & fees
9 Jan - 10 Jan 2026
Hôtel La Résidence Lyon
Restaurant
Bikube Lyon

Bikube Lyon

Bikube Lyon
4.0 star property
3rd Arrondissement, 1.1 km from La Guillotière
9.0 out of 10, Wonderful, (188)
"Everything was great! Staff were alway friendly and helpful! Room was immaculate. Shared living space was cool. Close to Metro. Highly recommend!"
United States
Kathleen
The price is 2.268.121 ₫
2.671.590 ₫ total
includes taxes & fees
2 Jan - 3 Jan 2026
Bikube Lyon
Bar (on property)
ibis Lyon Centre Perrache

ibis Lyon Centre Perrache

ibis Lyon Centre Perrache
3.0 star property
Perrache, 1.7 km from La Guillotière
8.8 out of 10, Excellent, (931)
"Clean with comfortable bed and good shower. In walking distance of places to visit. Near station."
United Kingdom
alan
The price is 2.123.697 ₫
2.451.573 ₫ total
includes taxes & fees
28 Dec - 29 Dec
ibis Lyon Centre Perrache
Daily buffet breakfast (EUR 20 per person)
OKKO Hotels Lyon Centre

OKKO Hotels Lyon Centre

OKKO Hotels Lyon Centre
4.0 star property
1.7 km from La Guillotière
9.0 out of 10, Wonderful, (1008)
"Fantastic hotel, welcoming staff. "
Canada
Carol
The price is 2.900.525 ₫
3.367.235 ₫ total
includes taxes & fees
14 Dec - 15 Dec
OKKO Hotels Lyon Centre
Classic Room, Garden View | Terrace/patio
The Ruck Hotel

The Ruck Hotel

The Ruck Hotel
4.0 star property
Gerland, 3.1 km from La Guillotière
9.0 out of 10, Wonderful, (208)
"Wasn’t a very good breakfast choice , staff were very helpful and efficient "
United Kingdom
yasmin
The price is 4.093.579 ₫
4.679.594 ₫ total
includes taxes & fees
31 Dec - 1 Jan 2026
The Ruck Hotel
Daily buffet breakfast (EUR 10 per person)
Premiere Classe Lyon Centre - Gare Part Dieu

Premiere Classe Lyon Centre - Gare Part Dieu

Premiere Classe Lyon Centre - Gare Part Dieu
2.0 star property
Part Dieu - Bir Hakeim, 1 km from La Guillotière
8.0 out of 10, Very good, (1002)
"Excellent stay , clean tiny hotel , excellent service , thank you"
Canada
Dorin
The price is 1.443.687 ₫
1.656.001 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Premiere Classe Lyon Centre - Gare Part Dieu
Classic Double Room | Premium bedding, in-room safe, blackout curtains, iron/ironing board
Republik Hôtel

Republik Hôtel

Republik Hôtel
3.0 star property
Bellecour - Hôtel Dieu, 1.5 km from La Guillotière
8.6 out of 10, Excellent, (335)
"Everything was great!"
Canada
Polina
The price is 3.200.819 ₫
3.636.407 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Republik Hôtel
Junior Suite | 10 bedrooms, desk, blackout curtains, soundproofing
Hotel Vaubecour

Hotel Vaubecour

Hotel Vaubecour
2.0 star property
2nd Arrondissement, 1.9 km from La Guillotière
9.2 out of 10, Wonderful, (324)
"This hotel is located in a great area with easy access to the train station, metro stations, and lots of shopping and restaurants. The staff is very nice and helpful. Would definitely stay here again!"
Canada
Nicholas
The price is 2.330.199 ₫
2.631.318 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Hotel Vaubecour
In-room safe, desk, blackout curtains, free WiFi
Hôtel des Célestins

Hôtel des Célestins

Hôtel des Célestins
3.0 star property
Bellecour - Hôtel Dieu, 1.7 km from La Guillotière
9.0 out of 10, Wonderful, (391)
"This is the perfect location and a beautiful smaller hotel, highly recommend."
United States
Steven
The price is 2.729.023 ₫
3.117.431 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Hôtel des Célestins
Exterior
Hotel Silky by HappyCulture

Hotel Silky by HappyCulture

Hotel Silky by HappyCulture
4.0 star property
Les Cordeliers, 1.9 km from La Guillotière
8.8 out of 10, Excellent, (969)
"Amazing location and hotel. Perfect for seeing the sites and coming back and feeling welcomed by the staff. Great breakfast too!"
Canada
Cameron
The price is 2.779.561 ₫
3.234.175 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Hotel Silky by HappyCulture
Terrace/patio
Globe et Cecil Hôtel

Globe et Cecil Hôtel

Globe et Cecil Hôtel
4.0 star property
Bellecour - Hôtel Dieu, 1.6 km from La Guillotière
8.4 out of 10, Very good, (528)
"Very nice stay, loved the location and the hotel! "
Sweden
Sandra
The price is 3.596.443 ₫
4.132.899 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Globe et Cecil Hôtel
Deluxe Studio (with Air Conditioning) | In-room safe, desk, blackout curtains, soundproofing
Citadines Presqu'île Lyon

Citadines Presqu'île Lyon

Citadines Presqu'île Lyon
3.0 star property
Les Cordeliers, 1.8 km from La Guillotière
8.4 out of 10, Very good, (1251)
"Amazing property! Great staff and location!"
United States
Rachel
The price is 3.060.325 ₫
3.481.863 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Citadines Presqu'île Lyon
Daily buffet breakfast (EUR 16 per person)
Hotel du Simplon

Hotel du Simplon

Hotel du Simplon
3.0 star property
Carnot - Gailleton, 1.6 km from La Guillotière
8.4 out of 10, Very good, (1002)
"Great location and great value!"
United States
Cyrus
The price is 2.486.163 ₫
2.850.291 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Hotel du Simplon
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in La Guillotière

Find the best La Guillotière areas for the activities you enjoy most.

Lyon City Centre

Gourmet restaurants interesting history and top sights from Bellecour Square to Hôtel-Dieu – discover Lyon City Centre, a destination also famous for its shopping.

Lyon showing a city, a river or creek and a statue or sculpture

Old Lyon

If you're spending time in Old Lyon, you might enjoy attractions like Lyon Cathedral and Palais de Justice de Lyon. You might also enjoy the neighbourhood's ample dining options before hopping on the metro at Vieux Lyon Station to see more of the city.

Bellecour Square which includes a statue or sculpture, a river or creek and a bridge

Bellecour - Hôtel Dieu

While you're in Bellecour - Hôtel Dieu, take in top sights like Bellecour Square and jump on the metro at Bellecour Station to see more of the city.

3rd Arrondissement

Noted for its shopping and river views, there's plenty to explore in 3rd Arrondissement. Top attractions like Part Dieu Mall and Halles de Lyon - Paul Bocuse are major draws, and you can hop on the metro at Dauphine - Lacassagne Tram Stop or Archives Départementales Tram Stop to see more of the city.

2nd Arrondissement

Travellers love 2nd Arrondissement for its popular shops, and you can see more of Lyon by jumping on the metro at Place des Archives or Sainte-Blandine Tram Stop. You might spend time checking out top sights like Place Carnot and Lyon Confluence Shopping Center.

Top La Guillotière Hotel Reviews

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Frequently asked questions

What is La Guillotière like?
La Guillotière is a neighbourhood that travellers like for its riverfront, shopping and restaurants.
How many hotels should I expect to find in the La Guillotière area?
If you're searching for places to stay in Lyon, Expedia has something to meet your needs with 42 La Guillotière hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in La Guillotière, will I receive a refund?
Yes, you'll find most room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and get a refund within a 24-hour period of booking. Add your dates and click on "Search", then you can filter by "fully refundable" to review top deals in La Guillotière.
What is there to do around this Lyon neighbourhood?
Carrousel du Pont de la Guillotière, Museum of the Resistance and Centre d'Histoire de la Resistance et de la Deportation are just a few of the places to visit in and around La Guillotière. La Part-Dieu Business District and Tour Part-Dieu are also worth a visit when you're out sightseeing in Lyon.
How can I get around La Guillotière and the greater Lyon area?
For a quick way to explore the city, catch a ride on metro transit at Garibaldi Station, Saxe-Gambetta Station or Saint-André Tram Stop.