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Search Hotels in Lakeshore South, Jacksonville

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Our top choices for Lakeshore South hotels

Lobby lounge
Wyndham Garden Jacksonville

Wyndham Garden Jacksonville

Wyndham Garden Jacksonville
3.0 star property
Baymeadows, 13.5 km from Lakeshore South
7.8 out of 10, Good, (1773)
"Quick check in, clean room, accessible to all the highways ! "
United States
Megan Rose
The price is 1.837.083 ₫
2.085.089 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Wyndham Garden Jacksonville
Standard Double Room, 2 Double Beds, Smoking | Premium bedding, down duvets, in-room safe, blackout curtains
San Marco Inn East

San Marco Inn East

San Marco Inn East
3.0 star property
8.6 km from Lakeshore South
8.4 out of 10, Very good, (1256)
"Nice clean rooms, safe environment and very friendly staff."
United States
Parry J
San Marco Inn East
View from property
DoubleTree by Hilton Hotel Jacksonville Riverfront

DoubleTree by Hilton Hotel Jacksonville Riverfront

DoubleTree by Hilton Hotel Jacksonville Riverfront
4.0 star property
Southbank, 7.7 km from Lakeshore South
6.8 out of 10, (1472)
"Loved the hotel "
United States
lucy
The price is 2.399.014 ₫
2.722.881 ₫ total
includes taxes & fees
21 Dec - 22 Dec
DoubleTree by Hilton Hotel Jacksonville Riverfront
Property amenity
WaterWalk Extended Stay by Wyndham Jacksonville Deerwood Pk

WaterWalk Extended Stay by Wyndham Jacksonville Deerwood Pk

WaterWalk Extended Stay by Wyndham Jacksonville Deerwood Pk
2.0 star property
16.3 km from Lakeshore South
8.8 out of 10, Excellent, (743)
"Staff were great an accommodating. Room was nice and clean. Already booked another stay in January."
United States
Derek
The price is 3.136.483 ₫
3.559.909 ₫ total
includes taxes & fees
14 Dec - 15 Dec
WaterWalk Extended Stay by Wyndham Jacksonville Deerwood Pk
Property amenity
Days Inn by Wyndham Orange Park/Jacksonville

Days Inn by Wyndham Orange Park/Jacksonville

Days Inn by Wyndham Orange Park/Jacksonville
2.0 star property
10.5 km from Lakeshore South
7.6 out of 10, Good, (1001)
"Friendly and courteous staff, clean room, very good dining options around."
United States
Ben Jasad
The price is 1.748.595 ₫
1.967.169 ₫ total
includes taxes & fees
10 Jan - 11 Jan 2026
Days Inn by Wyndham Orange Park/Jacksonville
Exterior
Holiday Inn Express & Suites Jacksonville Airport by IHG

Holiday Inn Express & Suites Jacksonville Airport by IHG

Holiday Inn Express & Suites Jacksonville Airport by IHG
2.5 star property
Northside, 23.4 km from Lakeshore South
8.6 out of 10, Excellent, (1011)
"Front desk check in was excellent!"
United States
Janet
The price is 2.319.416 ₫
2.632.537 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Holiday Inn Express & Suites Jacksonville Airport by IHG
Restaurant
Extended Stay America Premier Suites - Jacksonville - Airport

Extended Stay America Premier Suites - Jacksonville - Airport

Extended Stay America Premier Suites - Jacksonville - Airport
2.5 star property
Northside, 25 km from Lakeshore South
9.0 out of 10, Wonderful, (98)
"Will stay here again "
United States
Jose
The price is 1.897.440 ₫
2.153.630 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Extended Stay America Premier Suites - Jacksonville - Airport
Lobby
Hilton Jacksonville At Mayo Clinic

Hilton Jacksonville At Mayo Clinic

Hilton Jacksonville At Mayo Clinic
4.5 star property
27.1 km from Lakeshore South
9.2 out of 10, Wonderful, (53)
"Beautiful hotel. Close to Mayo Clinic."
United States
Patty
The price is 3.220.298 ₫
3.655.039 ₫ total
includes taxes & fees
20 Dec - 21 Dec
Hilton Jacksonville At Mayo Clinic
Lobby
Hyatt Place Jacksonville Airport

Hyatt Place Jacksonville Airport

Hyatt Place Jacksonville Airport
3.0 star property
Northside, 23.1 km from Lakeshore South
9.0 out of 10, Wonderful, (2267)
"Room eas clean staff was great"
United States
Joshua
The price is 2.553.993 ₫
2.898.781 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Hyatt Place Jacksonville Airport
Daily buffet breakfast (USD 26.95 per person)
Hyatt Regency Jacksonville

Hyatt Regency Jacksonville

Hyatt Regency Jacksonville
4.0 star property
Downtown Jacksonville, 8.1 km from Lakeshore South
9.0 out of 10, Wonderful, (1381)
"Nice stay"
United States
April
The price is 3.795.408 ₫
4.350.867 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Hyatt Regency Jacksonville
Exterior
WoodSpring Suites Jacksonville - South

WoodSpring Suites Jacksonville - South

WoodSpring Suites Jacksonville - South
2.5 star property
Southside, 13.1 km from Lakeshore South
7.6 out of 10, Good, (647)
"I love the hotel and enjoyed my stay."
United States
Marcus
The price is 1.686.848 ₫
1.914.572 ₫ total
includes taxes & fees
14 Dec - 15 Dec
WoodSpring Suites Jacksonville - South
Exterior
DoubleTree by Hilton Hotel Jacksonville Airport

DoubleTree by Hilton Hotel Jacksonville Airport

DoubleTree by Hilton Hotel Jacksonville Airport
4.0 star property
Northside, 23.5 km from Lakeshore South
8.4 out of 10, Very good, (1711)
"The food was wonderful they staff was friendly the cookies are amazing "
United States
Ebony
The price is 2.463.852 ₫
2.796.473 ₫ total
includes taxes & fees
23 Dec - 24 Dec
DoubleTree by Hilton Hotel Jacksonville Airport
Lobby
Southbank Hotel by Marriott Jacksonville Riverwalk

Southbank Hotel by Marriott Jacksonville Riverwalk

Southbank Hotel by Marriott Jacksonville Riverwalk
3.5 star property
Southbank, 7.7 km from Lakeshore South
8.2 out of 10, Very good, (1606)
"We liked our stay"
United States
Lorie
The price is 2.585.622 ₫
2.934.681 ₫ total
includes taxes & fees
2 Jan - 3 Jan 2026
Southbank Hotel by Marriott Jacksonville Riverwalk
Lobby sitting area
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
2.5 star property
25.1 km from Lakeshore South
8.6 out of 10, Excellent, (1005)
"Good location for a family vacation "
United States
Angel
The price is 2.767.485 ₫
3.141.095 ₫ total
includes taxes & fees
19 Dec - 20 Dec
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
Desk, laptop workspace, blackout curtains, iron/ironing board
Airport Motor Inn

Airport Motor Inn

Airport Motor Inn
2.5 star property
Northside, 23.3 km from Lakeshore South
8.6 out of 10, Excellent, (40)
"Very clean and quiet."
United States
Sylvia
The price is 1.683.949 ₫
1.911.146 ₫ total
includes taxes & fees
12 Dec - 13 Dec
Airport Motor Inn
Free daily buffet breakfast
Comfort Suites Baymeadows Near Butler Blvd

Comfort Suites Baymeadows Near Butler Blvd

Comfort Suites Baymeadows Near Butler Blvd
3.0 star property
16.6 km from Lakeshore South
8.2 out of 10, Very good, (1002)
"Enjoyed our stay! Staff was awesome....very clean and quiet stay."
United States
Rita
The price is 2.557.420 ₫
2.902.672 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Comfort Suites Baymeadows Near Butler Blvd
Exterior
Hotel Indigo Jacksonville-Deerwood Park by IHG

Hotel Indigo Jacksonville-Deerwood Park by IHG

Hotel Indigo Jacksonville-Deerwood Park by IHG
3.5 star property
Southside, 16.7 km from Lakeshore South
9.2 out of 10, Wonderful, (1001)
"Very nice stay "
United States
Timmothy
The price is 3.004.698 ₫
3.410.333 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Hotel Indigo Jacksonville-Deerwood Park by IHG
Property amenity
Sheraton Jacksonville Hotel

Sheraton Jacksonville Hotel

Sheraton Jacksonville Hotel
4.0 star property
Deerwood, 18.3 km from Lakeshore South
9.2 out of 10, Wonderful, (1001)
"Good hotel!"
United States
Charlie
The price is 2.352.362 ₫
2.669.932 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Sheraton Jacksonville Hotel
BBQ/picnic Area
Residence Inn by Marriott Jacksonville Butler Boulevard

Residence Inn by Marriott Jacksonville Butler Boulevard

Residence Inn by Marriott Jacksonville Butler Boulevard
3.0 star property
Deerwood, 18 km from Lakeshore South
8.8 out of 10, Excellent, (1000)
"The two bedroom/two bath suite with kitchen was absolutely perfect and the staff was friendly and helpful."
United States
Shauna
The price is 2.503.915 ₫
2.841.944 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Residence Inn by Marriott Jacksonville Butler Boulevard
Exterior
Crowne Plaza Hotel Jacksonville Airport/I-95N by IHG

Crowne Plaza Hotel Jacksonville Airport/I-95N by IHG

Crowne Plaza Hotel Jacksonville Airport/I-95N by IHG
3.5 star property
Northside, 23.3 km from Lakeshore South
8.4 out of 10, Very good, (1785)
"Excellent service at front desk, generally pleasant and gave me tips walking distance"
United States
Janee
The price is 2.452.410 ₫
2.783.487 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Crowne Plaza Hotel Jacksonville Airport/I-95N by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Lakeshore South

Find the best Lakeshore South areas for the activities you enjoy most.
Photo by Ryan Ketterman
Open Photo by Ryan Ketterman

Downtown Jacksonville

Florida Theatre and Jacksonville Museum of Modern Art are top sights in Downtown Jacksonville, and you should be sure to explore the stunning river views. Hop aboard the metro at Riverplace Station or Kings Avenue Station to see more sights in the area.

Amelia City

While visiting Amelia City, you might make a stop by sights like American Beach and Fernandina Beach.

Southside

If you're spending some time in Southside, St. Johns Town Center and Merill Road Shopping Center are top sights worth seeing.

Sawgrass

Beaches and riverfront are just a few things travellers like about Sawgrass. A stop by Mickler Beach is also recommended if you've got time to explore the area.

Cummer Museum of Art and Gardens featuring art and interior views as well as a couple
Photo by Visit Jacksonville
Open Photo by Visit Jacksonville

Northwest

While visiting Northwest, you might make a stop by sights like Cummer Museum of Art and Gardens and Jacksonville-Baldwin Rail Trail.

Top Lakeshore South Hotel Reviews

Weekly Inn

Weekly Inn

10/10 Excellent
"Very clean rooms and friendly staff, would recommend to anyone! 🙏"
Dournell 1-night trip
Posted 5 days ago
Weekly Inn
Hilton Jacksonville At Mayo Clinic

Hilton Jacksonville At Mayo Clinic

10/10 Excellent
"Clean. Very friendly staff."
Mark 1-night trip
Posted 10 days ago
Hilton Jacksonville At Mayo Clinic

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Frequently asked questions

What's it like in Lakeshore South?
Travellers to the Lakeshore South neighbourhood in Jacksonville will be sure to enjoy their stay. Are you looking for Lakeshore South travel tips? Make sure that you visit Sadler Point Marina and Ortega Yacht Club Marina while you're in the neighbourhood.
How many hotels will I find in the Lakeshore South area?
Expedia has 35 hotels and other accommodation options in Lakeshore South to choose from, making this an ideal home base for exploring the greater Jacksonville area.
If I need to cancel my hotel reservation in Lakeshore South, will I receive a refund?
Yes! Most hotel reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you booked a non-refundable reservation, you might be able to still cancel and receive a refund within a 24-hour period of booking. Add dates, click "Search", then use the "fully refundable" filter to get the top deals on offer in Lakeshore South.
What can I see and do in this Jacksonville neighbourhood?
If you've got some time for activities in Lakeshore South, you won't be disappointed by Sadler Point Marina, Ortega Yacht Club Marina and Lambs Marina. You could also plan a visit to Ceder Point Marina or Museum of Southern History while you're in the neighbourhood. A few places to visit in the area around Lakeshore South include Pine Wood Park, Lighthouse Marina and Cedar Hills Shopping Center. When you're sightseeing in Jacksonville, Hyde Park Golf Club and Paxon Shopping Center are also worth a stop.