Search Hotels Near Lexington Medical Center, West Columbia

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23 Dec - 24 Dec
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26 Dec - 28 Dec
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Our top choices for Lexington Medical Center hotels

Free daily continental breakfast
Residence Inn Columbia West/Lexington

Residence Inn Columbia West/Lexington

Residence Inn Columbia West/Lexington
3.0 star property
0.4 km from Lexington Medical Center
9.2 out of 10, Wonderful, (357)
"Was overall pleased with services and hotel stay."
United States
VIctoria
The price is 3.054.396 ₫
3.298.747 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Residence Inn Columbia West/Lexington
Terrace/patio
TownePlace Suites Columbia West/Lexington

TownePlace Suites Columbia West/Lexington

TownePlace Suites Columbia West/Lexington
3.0 star property
0.5 km from Lexington Medical Center
9.2 out of 10, Wonderful, (452)
"The room was clean, staff was nice. Good price for an aparthotel."
United States
Kalea
The price is 3.133.389 ₫
3.384.060 ₫ total
includes taxes & fees
28 Dec - 29 Dec
TownePlace Suites Columbia West/Lexington
Terrace/patio
Hilton Garden Inn Columbia Airport

Hilton Garden Inn Columbia Airport

Hilton Garden Inn Columbia Airport
3.0 star property
0.5 km from Lexington Medical Center
9.0 out of 10, Wonderful, (1005)
"Staff was friendly and breakfast and dinner were yummy ! "
United States
kelsey
The price is 3.069.141 ₫
3.341.140 ₫ total
includes taxes & fees
30 Dec - 31 Dec
Hilton Garden Inn Columbia Airport
Exterior
Hampton Inn Columbia-I-26 Airport

Hampton Inn Columbia-I-26 Airport

Hampton Inn Columbia-I-26 Airport
2.5 star property
0.6 km from Lexington Medical Center
8.2 out of 10, Very good, (1002)
"Great staff, very clean and a wonderful hot breakfast."
United States
Audrey
The price is 2.353.465 ₫
2.601.250 ₫ total
includes taxes & fees
23 Jan - 24 Jan 2026
Hampton Inn Columbia-I-26 Airport
Lobby
Sleep Inn Columbia

Sleep Inn Columbia

Sleep Inn Columbia
2.5 star property
2.8 km from Lexington Medical Center
8.2 out of 10, Very good, (1000)
"The room was clean, the staff was very attentive and courteous!"
United States
Felddy
The price is 2.215.754 ₫
2.393.014 ₫ total
includes taxes & fees
19 Jan - 20 Jan 2026
Sleep Inn Columbia
Suite, 1 King Bed, Non Smoking, Microwave | Pillow-top beds, desk, laptop workspace, WiFi
Best Western Executive Inn & Suites

Best Western Executive Inn & Suites

Best Western Executive Inn & Suites
2.5 star property
2.6 km from Lexington Medical Center
8.0 out of 10, Very good, (719)
"The staff was awesome!"
United States
Kayla
The price is 2.896.147 ₫
3.127.860 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Best Western Executive Inn & Suites
Lobby
Doubletree by Hilton Columbia, SC

Doubletree by Hilton Columbia, SC

Doubletree by Hilton Columbia, SC
4.0 star property
3 km from Lexington Medical Center
8.0 out of 10, Very good, (1000)
"Room was very nice quiet and spacious. I really enjoyed my visit!"
United States
Derrick
The price is 2.569.574 ₫
2.834.652 ₫ total
includes taxes & fees
29 Dec - 30 Dec
Doubletree by Hilton Columbia, SC
Lobby
Comfort Inn Columbia West

Comfort Inn Columbia West

Comfort Inn Columbia West
2.5 star property
2.9 km from Lexington Medical Center
7.4 out of 10, Good, (1000)
"Staff was very polite, knowledgeable and helpful. The facility could use renovations. I also saw a bug crawling on the desk! "
United States
Linda M. Russell
The price is 1.895.832 ₫
2.123.332 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Comfort Inn Columbia West
Lobby
Quality Inn Columbia Airport

Quality Inn Columbia Airport

Quality Inn Columbia Airport
2.5 star property
2.8 km from Lexington Medical Center
6.8 out of 10, (1000)
"Friendly staff, good parking, comfortable bed & pillows."
United States
Stephen
The price is 1.555.635 ₫
1.680.086 ₫ total
includes taxes & fees
23 Jan - 24 Jan 2026
Quality Inn Columbia Airport
Exterior
Knights Inn Columbia

Knights Inn Columbia

Knights Inn Columbia
1.5 star property
2.6 km from Lexington Medical Center
6.4 out of 10, (549)
"For an older property, it was clean, comfortable and affordable. "
United States
Kearney
The price is 1.974.825 ₫
2.132.811 ₫ total
includes taxes & fees
25 Dec - 26 Dec
Knights Inn Columbia
Bar (on property)
Clarion Inn Columbia Airport

Clarion Inn Columbia Airport

Clarion Inn Columbia Airport
2.5 star property
2.7 km from Lexington Medical Center
6.0 out of 10, (1000)
"Room was okay...everything works & water gets very hot.. Not much staff around, so if you happen to show up round checkout time you may have to wait a bit for clerk/housekeeping. "
United States
James
The price is 1.535.477 ₫
1.658.315 ₫ total
includes taxes & fees
10 Jan - 11 Jan 2026
Clarion Inn Columbia Airport
Premium bedding, down duvets, pillow-top beds, in-room safe
Baymont by Wyndham Columbia Northwest

Baymont by Wyndham Columbia Northwest

Baymont by Wyndham Columbia Northwest
2.5 star property
3.1 km from Lexington Medical Center
5.4 out of 10, (1001)
"Friendly staff"
United States
Joseph
The price is 1.348.556 ₫
1.510.385 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Baymont by Wyndham Columbia Northwest
Seasonal outdoor pool
Days Inn by Wyndham Columbia

Days Inn by Wyndham Columbia

Days Inn by Wyndham Columbia
2.0 star property
2.8 km from Lexington Medical Center
4.2 out of 10, (1003)
"Front desk very professional along with staff"
United States
Angela
The price is 1.606.191 ₫
1.798.934 ₫ total
includes taxes & fees
25 Dec - 26 Dec
Days Inn by Wyndham Columbia
TV
Columbia Duet - 2 Units

Columbia Duet - 2 Units

Columbia Duet - 2 Units
3.0 star property
2.9 km from Lexington Medical Center
The price is 9.227.962 ₫
36.289.827 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Columbia Duet - 2 Units
TV
Columbia Duet Unit B

Columbia Duet Unit B

Columbia Duet Unit B
2.0 star property
2.9 km from Lexington Medical Center
The price is 5.406.281 ₫
21.208.717 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Columbia Duet Unit B
Seasonal outdoor pool
Lexington Expo Hotel by IHG

Lexington Expo Hotel by IHG

Lexington Expo Hotel by IHG
3.0 star property
3.5 km from Lexington Medical Center
9.2 out of 10, Wonderful, (1000)
"Great location "
United States
Konrad
The price is 2.738.632 ₫
3.039.881 ₫ total
includes taxes & fees
29 Dec - 30 Dec
Lexington Expo Hotel by IHG
Exterior
Tru By Hilton Columbia Greystone

Tru By Hilton Columbia Greystone

Tru By Hilton Columbia Greystone
2.5 star property
3.8 km from Lexington Medical Center
9.2 out of 10, Wonderful, (1006)
"Nice place to stay"
United States
Beth
The price is 2.569.379 ₫
2.929.090 ₫ total
includes taxes & fees
30 Dec - 31 Dec
Tru By Hilton Columbia Greystone
Lobby
Hampton Inn & Suites Lexington Columbia

Hampton Inn & Suites Lexington Columbia

Hampton Inn & Suites Lexington Columbia
2.5 star property
5.5 km from Lexington Medical Center
9.8 out of 10, Exceptional, (596)
"Clean and comfortable room, friendly staff, great location."
United States
Allison
The price is 2.612.562 ₫
2.899.943 ₫ total
includes taxes & fees
16 Jan - 17 Jan 2026
Hampton Inn & Suites Lexington Columbia
The Darling Suite | Premium bedding, pillow-top beds, in-room safe, individually decorated
Hotel Trundle

Hotel Trundle

Hotel Trundle
3.0 star property
7.2 km from Lexington Medical Center
9.8 out of 10, Exceptional, (992)
"Very clean. Staff very nice and friendly. I would definitely stay there again"
United States
Leslie
The price is 3.660.009 ₫
4.099.209 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Hotel Trundle
Living area
Homewood Suites By Hilton Columbia Downtown

Homewood Suites By Hilton Columbia Downtown

Homewood Suites By Hilton Columbia Downtown
3.0 star property
6.3 km from Lexington Medical Center
9.6 out of 10, Exceptional, (93)
"Staff is very helpful. Rooms are clean and spacious."
United States
Crystal
The price is 3.001.207 ₫
3.361.352 ₫ total
includes taxes & fees
30 Dec - 31 Dec
Homewood Suites By Hilton Columbia Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Lexington Medical Center Hotel Reviews

Hotels near other Lexington Medical Center attractions

Animals in the zoo. Wild African animals in a summer forest on a sunny day. Outdoor activities with children. Riverbanks Zoo and Garden, Columbia, South Carolina, USA. American flamingos in the zoo

Riverbanks Zoo and Garden

4.4/5 (613 reviews)
Why not meet the animals who call Riverbanks Zoo and Garden home during your holiday in Columbia? You can attend a sporting event while in the area.
See properties
The view at the end of the canal trail from Columbia's Riverfront Park. It is a beautiful city park! For a video guide of the park and trail, please visit: https://www.hdcarolina.com/episode/riverfront-park-canal-trail
Photo by Ryan Watts
Open Photo by Ryan Watts

Columbia Canal and Riverfront Park

Explore the great outdoors at Columbia Canal and Riverfront Park, a lovely green space in Columbia. Experience the area's acclaimed theatre scene or attend a sporting event.
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Frequently asked questions

What's the area like around Lexington Medical Center?
Lexington Medical Center is located in West Columbia. Travellers like the surrounding area for its bars. If you're looking for a convenient place to stay, take a look at the 17 hotels and other accommodation options you'll find within a mile.
How many hotels are there near Lexington Medical Center?
Expedia has 17 hotels and other accommodation options within a mile from Lexington Medical Center.
If I need to cancel the hotel reservation for my stay near Lexington Medical Center, will I receive a refund?
Yes! The majority of hotel reservations are fully refundable if you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of your check-in date. If you have a reservation that's non-refundable, you might still have the option to cancel and receive a refund within a 24-hour period of booking. Put your dates in and click on "Search", then use the filter option "fully refundable" to review the best options available near Lexington Medical Center.
What can I see and do near Lexington Medical Center?
Study the collections at South Carolina State Museum, Columbia Museum of Art or Cayce Historical Museum. While you're exploring, swing by South Carolina State House, Governor's Mansion and First Baptist Church to learn a bit about the area. You can check out the local talent at Koger Center for the Arts, Township Auditorium and Columbia Marionette Theater.