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Check availability on Lyon City Centre Business Hotels

Our top choices for Lyon City Centre business-friendly hotels

Exterior
Le Phenix Hotel

Le Phenix Hotel

Le Phenix Hotel
4.0 star property
Lyon City Centre
9.2 out of 10, Wonderful, (1001)
"Fantastic location with excellent rooms"
United States
Hudson
The price is 3.121.779 ₫
3.609.317 ₫ total
includes taxes & fees
18 Dec - 19 Dec
Le Phenix Hotel
Exterior
Campanile PRIME - Lyon Centre Gare Part Dieu

Campanile PRIME - Lyon Centre Gare Part Dieu

Campanile PRIME - Lyon Centre Gare Part Dieu
3.0 star property
Lyon City Centre
9.0 out of 10, Wonderful, (1192)
"Nice place to stay."
United States
Yuanmei
The price is 2.132.458 ₫
2.460.383 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Campanile PRIME - Lyon Centre Gare Part Dieu
View from property
Hôtel La Résidence Lyon

Hôtel La Résidence Lyon

Hôtel La Résidence Lyon
3.0 star property
Lyon City Centre
8.4 out of 10, Very good, (1000)
"Ccclean room, nice staff, close to central train station Perrache"
United States
Gerhardus
The price is 2.501.470 ₫
2.866.357 ₫ total
includes taxes & fees
9 Jan - 10 Jan 2026
Hôtel La Résidence Lyon
View from property
Fourvière Hôtel Lyon

Fourvière Hôtel Lyon

Fourvière Hôtel Lyon
4.0 star property
Lyon City Centre
9.2 out of 10, Wonderful, (1001)
"This property was excellent "
United States
Ed
Fourvière Hôtel Lyon
Breakfast, lunch, dinner served; Regional cuisine
Radisson Blu Hotel Lyon

Radisson Blu Hotel Lyon

Radisson Blu Hotel Lyon
4.0 star property
Lyon City Centre
8.4 out of 10, Very good, (1001)
"It was great. The room was clean and comfortable. The staff were helpful and friendly"
United States
Glenn
The price is 3.400.782 ₫
3.916.251 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Radisson Blu Hotel Lyon
Terrace/patio
Maison Nô

Maison Nô

Maison Nô
4.0 star property
Lyon City Centre
9.0 out of 10, Wonderful, (399)
"Very good location and staff is very nice and room is perfect "
United Kingdom
Cheryl
The price is 2.582.681 ₫
3.017.361 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Maison Nô
Reception
Best Western Hotel Du Pont Wilson

Best Western Hotel Du Pont Wilson

Best Western Hotel Du Pont Wilson
4.0 star property
Lyon City Centre
8.4 out of 10, Very good, (620)
"Hotel staff was very friendly and helpful. The hotel is located close to the river and not far from Old Lyon. The room was nice and the amenities were good: The bed was comfortable and the shower was great."
United States
John
The price is 2.722.729 ₫
3.171.414 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Best Western Hotel Du Pont Wilson
Reception
Hôtel Le Roosevelt

Hôtel Le Roosevelt

Hôtel Le Roosevelt
4.0 star property
Lyon City Centre
9.4 out of 10, Exceptional, (203)
"Room spotless, staff lovely "
United Kingdom
Jack
The price is 2.967.497 ₫
3.440.659 ₫ total
includes taxes & fees
9 Jan - 10 Jan 2026
Hôtel Le Roosevelt
Meeting facility
Novotel Lyon Centre Confluence Bord de Saone

Novotel Lyon Centre Confluence Bord de Saone

Novotel Lyon Centre Confluence Bord de Saone
4.0 star property
Lyon City Centre
8.8 out of 10, Excellent, (870)
"Breakfast was excelent. "
United States
Francisco J
The price is 2.860.838 ₫
3.322.312 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Novotel Lyon Centre Confluence Bord de Saone
Terrace/patio
ibis Lyon Gare la Part Dieu

ibis Lyon Gare la Part Dieu

ibis Lyon Gare la Part Dieu
3.0 star property
Lyon City Centre
8.2 out of 10, Very good, (1000)
"Location near train station "
Canada
Albert
The price is 1.895.518 ₫
2.199.749 ₫ total
includes taxes & fees
23 Dec - 24 Dec
ibis Lyon Gare la Part Dieu
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Lyon City Centre Hotel Reviews

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Frequently asked questions

Why book your business-friendly hotel in Lyon City Centre with Expedia?
At Expedia, we make it our business to help you land the perfect stay at the right price. From luxurious, corporate-friendly retreats to affordable motels filled with handy amenities, you'll have your next work trip organised in a few quick clicks.
How can I find cheap business-friendly hotels in Lyon City Centre?
Expedia can help you narrow your search for cheap business-friendly hotels in Lyon City Centre. Simply head to the "traveller experience" filter and click on "business friendly." This will show you properties with amenities designed to help you work comfortably and efficiently, like free WiFi and included breakfast. You can also choose your preferred star rating and budget to keep costs down.