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17 Mar - 18 Mar
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Our top choices for Mayo Clinic Florida hotels

Breakfast, lunch, dinner served; American cuisine

Hilton Jacksonville At Mayo Clinic

Hilton Jacksonville At Mayo Clinic
4.5 star property
0.8 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (175 reviews)
"Great place to stay"
United States
Judy
The price is 4.483.340 ₫
5.088.590 ₫ total
includes taxes & fees
28 Mar - 29 Mar
Hilton Jacksonville At Mayo Clinic
Lobby lounge

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Residence Inn By Marriott Jacksonville - Mayo Clinic Area
3.0 star property
1.1 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (471 reviews)
"Great stay! Clean room, friendly staff. "
United States
Sabrena
The price is 4.179.474 ₫
4.743.703 ₫ total
includes taxes & fees
5 Apr - 6 Apr
Residence Inn By Marriott Jacksonville - Mayo Clinic Area
Terrace/patio

TownePlace Suites by Marriott Jacksonville East

TownePlace Suites by Marriott Jacksonville East
3.0 star property
Golden Glades - The Woods, 3.1 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (589 reviews)
"Very nice accommodation , clean , and comfortable"
United States
Kevin
The price is 3.128.034 ₫
3.550.318 ₫ total
includes taxes & fees
30 Mar - 31 Mar
TownePlace Suites by Marriott Jacksonville East
Lobby

Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
2.5 star property
Golden Glades - The Woods, 3.1 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,002 reviews)
"Nice room nice stay friendly staff"
United States
Thomas
The price is 2.888.306 ₫
3.278.226 ₫ total
includes taxes & fees
5 Apr - 6 Apr
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
Lobby sitting area

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
2.5 star property
2.6 km from Mayo Clinic Florida
8.8 out of 10, Excellent, (1,000 reviews)
"The staff was very friendly and knowledgeable and the morning breakfast was very good. Will be staying again in the future "
United States
Kimberly
The price is 2.944.032 ₫
3.341.477 ₫ total
includes taxes & fees
22 Mar - 23 Mar
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
Terrace/patio

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches

Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches
3.0 star property
0.4 km from Mayo Clinic Florida
8.4 out of 10, Very good, (766 reviews)
"Room very clear; staff friendly and helpful; safe parking with accessibility to Mayo Clinic "
United States
Nancy
The price is 4.232.368 ₫
4.803.737 ₫ total
includes taxes & fees
3 Apr - 4 Apr
Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches
Property amenity

Element Jacksonville Beach

Element Jacksonville Beach
3.0 star property
5.4 km from Mayo Clinic Florida
9.6 out of 10, Exceptional, (541 reviews)
"Rooms were clean. Proximity to beach was optimal. Daily made to order breakfast was simply amazing. "
United States
Sean M
The price is 4.232.046 ₫
4.803.372 ₫ total
includes taxes & fees
5 Apr - 6 Apr
Element Jacksonville Beach
Exterior

Holiday Inn Express & Suites Jacksonville - Town Center by IHG

Holiday Inn Express & Suites Jacksonville - Town Center by IHG
2.5 star property
Southside, 7.7 km from Mayo Clinic Florida
9.6 out of 10, Exceptional, (1,007 reviews)
"Great location, friendly staff, nice rooms, great breakfast."
United States
Michelle
The price is 3.101.748 ₫
3.520.484 ₫ total
includes taxes & fees
2 Apr - 3 Apr
Holiday Inn Express & Suites Jacksonville - Town Center by IHG
Standard Room, 1 King Bed, Non Smoking | Down duvets, minibar, iron/ironing board, WiFi

The Hotel Palms

The Hotel Palms
3.5 star property
7.8 km from Mayo Clinic Florida
9.6 out of 10, Exceptional, (294 reviews)
"stayed here for an event and it was awesome"
United States
clayton
The price is 4.968.054 ₫
5.638.873 ₫ total
includes taxes & fees
2 Apr - 3 Apr
The Hotel Palms
Property amenity

TownePlace Suites by Marriott® Jacksonville Mayport

TownePlace Suites by Marriott® Jacksonville Mayport
3.0 star property
10.8 km from Mayo Clinic Florida
9.8 out of 10, Exceptional, (88 reviews)
"Loved the staff, the cleanliness, and the food was excellent. Really enjoyed my stay here!!"
United States
Toni
The price is 3.758.898 ₫
4.266.349 ₫ total
includes taxes & fees
29 Mar - 30 Mar
TownePlace Suites by Marriott® Jacksonville Mayport
Exterior

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
2.5 star property
4.2 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,047 reviews)
"Great staff and Clean hotel "
United States
Tyniesha
The price is 3.427.169 ₫
3.889.836 ₫ total
includes taxes & fees
5 Apr - 6 Apr
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
Couples treatment room(s), sauna, hot tub, steam room, body treatments

Ponte Vedra Inn & Club

Ponte Vedra Inn & Club
5.0 star property
6.3 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (817 reviews)
"Wonderful place to visit to relax. Very clean, very friendly and courteous staff. Great view from the balcony."
United States
Greg
The price is 15.746.512 ₫
18.319.713 ₫ total
includes taxes & fees
16 Apr - 17 Apr
Ponte Vedra Inn & Club
2 restaurants, breakfast served

The Lodge and Club at Ponte Vedra Beach

The Lodge and Club at Ponte Vedra Beach
5.0 star property
6.3 km from Mayo Clinic Florida
9.4 out of 10, Exceptional, (689 reviews)
"Clean room, excellent service and only steps from the ocean. The facility could use some TLC but, all in all, a wonderful place to stay. We’ll be back for sure. "
United States
Robert
The price is 13.116.714 ₫
15.387.429 ₫ total
includes taxes & fees
12 Apr - 13 Apr
The Lodge and Club at Ponte Vedra Beach
Lobby

Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach
2.5 star property
5.9 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (3,747 reviews)
"Nice spot, friendly staff, nice bar and great beach location. "
United States
Keith
The price is 4.471.589 ₫
5.075.254 ₫ total
includes taxes & fees
5 Apr - 6 Apr
Margaritaville Jacksonville Beach
On the beach

Best Western Oceanfront

Best Western Oceanfront
3.0 star property
5.7 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,010 reviews)
"Great location, breakfast was delicious "
United States
Paul
The price is 3.364.601 ₫
3.818.858 ₫ total
includes taxes & fees
13 Apr - 14 Apr
Best Western Oceanfront
Sports facility

Hyatt Place Jacksonville / St. Johns Town Center

Hyatt Place Jacksonville / St. Johns Town Center
3.0 star property
Southside, 8.6 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (1,007 reviews)
"Great place to stay at!"
United States
R.
The price is 2.996.604 ₫
3.401.145 ₫ total
includes taxes & fees
5 Apr - 6 Apr
Hyatt Place Jacksonville / St. Johns Town Center
Lobby

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass
3.0 star property
8.5 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (1,004 reviews)
"Great stay all around "
United States
Jeffrey
The price is 4.138.468 ₫
4.614.392 ₫ total
includes taxes & fees
5 Apr - 6 Apr
Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass
Free daily buffet breakfast

Holiday Inn Express Jacksonville Beach by IHG

Holiday Inn Express Jacksonville Beach by IHG
3.0 star property
4.6 km from Mayo Clinic Florida
9.2 out of 10, Wonderful, (1,002 reviews)
"Great location for Jax beach and Players Championship "
United States
Robert
The price is 3.680.040 ₫
4.176.846 ₫ total
includes taxes & fees
30 Mar - 31 Mar
Holiday Inn Express Jacksonville Beach by IHG
Outdoor pool, pool umbrellas, pool loungers

Four Points by Sheraton Jacksonville Beachfront

Four Points by Sheraton Jacksonville Beachfront
3.0 star property
5.6 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (1,000 reviews)
"Good room"
United States
Michael
The price is 5.782.920 ₫
6.563.614 ₫ total
includes taxes & fees
13 Apr - 14 Apr
Four Points by Sheraton Jacksonville Beachfront
Bar (on property)

Springhill Suites By Marriott Jacksonville Beach Oceanfront

Springhill Suites By Marriott Jacksonville Beach Oceanfront
4.0 star property
5.8 km from Mayo Clinic Florida
9.0 out of 10, Wonderful, (650 reviews)
"Had an amazing getaway! "
United States
Meena
The price is 5.021.008 ₫
5.698.844 ₫ total
includes taxes & fees
13 Apr - 14 Apr
Springhill Suites By Marriott Jacksonville Beach Oceanfront
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Mayo Clinic Florida Hotel Reviews

Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach

10/10 Excellent
"Great ocean view and very comfortable, spacious room. "
Karen Ann 2-night trip
Posted 8 hours ago
Margaritaville Jacksonville Beach

Hotels near other Mayo Clinic Florida attractions

Windsor Parke Golf Club

Enjoy a round of golf in Jacksonville at Windsor Parke Golf Club. Amble around the area's beautiful beaches or attend a sporting event.
See properties

Windsor Commons Shopping Center

You can find the perfect gifts to bring home at Windsor Commons Shopping Center during your trip to Jacksonville. Experience the area's acclaimed theatre scene and great live music.
See properties

Frequently asked questions

What's the area like around Mayo Clinic Florida?
Mayo Clinic Florida is located in a welcoming area of Jacksonville known for its beautiful beaches and surfing. If you're looking for a convenient place to stay, take a look at the 49 hotels and other accommodation options you'll find within a mile.
How many hotels are there near Mayo Clinic Florida?
Expedia has 49 hotels and other accommodation options within a mile from Mayo Clinic Florida.
If I need to cancel the hotel reservation for my stay near Mayo Clinic Florida, will I receive a refund?
Yes! You'll find that most hotel bookings are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you have a non-refundable reservation, you may still be able to cancel and get a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to view the top deals on offer near Mayo Clinic Florida.
What can I see and do near Mayo Clinic Florida?
You can catch a show at SeaWalk Pavillion, Players by the Sea and SeaWalk Pavillion. Spend some time exploring the the natural beauty of Huguenot Park, Oceanfront Park and Cradle Creek Preserve. Lounge by the water at Northeast Florida Beaches and Ponte Vedra Beach.

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