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Check prices for these dates

Next weekend
19 Jun - 21 Jun
In two weeks
26 Jun - 28 Jun

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Our top choices for Mayo Lake hotels

Desk, blackout curtains, rollaway beds, free WiFi

Super 8 by Wyndham South Boston VA

Super 8 by Wyndham South Boston VA
2.0 star property
17.7 km from Mayo Lake
6.8 out of 10, (481 reviews)
"Clean room and easy parking and good ac"
United States
David
The price is 2.078.490 ₫
2.323.751 ₫ total
includes taxes & fees
21 Jun - 22 Jun
Super 8 by Wyndham South Boston VA
Blackout curtains, iron/ironing board, cots/infant beds, rollaway beds

Americas Best Value Inn Roxboro

Americas Best Value Inn Roxboro
2.0 star property
16.2 km from Mayo Lake
6.6 out of 10, (91 reviews)
"Someone should have notified incoming visitors of roof construction…"
United States
John
The price is 1.565.445 ₫
1.765.138 ₫ total
includes taxes & fees
1 Jul - 2 Jul
Americas Best Value Inn Roxboro
Reception

Budget Inn Roxboro

Budget Inn Roxboro
2.0 star property
16 km from Mayo Lake
6.4 out of 10, (170 reviews)
"Room was clean and staff was nice . "
United States
Jose
The price is 1.750.825 ₫
1.974.057 ₫ total
includes taxes & fees
15 Jun - 16 Jun
Budget Inn Roxboro
Lobby

Americas Best Value Inn & Suites South Boston

Americas Best Value Inn & Suites South Boston
2.0 star property
17.1 km from Mayo Lake
5.6 out of 10, (368 reviews)
"We left early to go to another lodging."
United States
Peter
The price is 1.453.628 ₫
1.617.888 ₫ total
includes taxes & fees
15 Jun - 16 Jun
Americas Best Value Inn & Suites South Boston
Free daily buffet breakfast

Fairfield Inn & Suites South Boston

Fairfield Inn & Suites South Boston
3.0 star property
17.7 km from Mayo Lake
8.8 out of 10, Excellent, (406 reviews)
"Staff very helpful."
United States
Dennis
The price is 3.393.990 ₫
3.794.481 ₫ total
includes taxes & fees
28 Jun - 29 Jun
Fairfield Inn & Suites South Boston
Free daily buffet breakfast

Hampton Inn Roxboro

Hampton Inn Roxboro
2.5 star property
19.3 km from Mayo Lake
9.0 out of 10, Wonderful, (354 reviews)
"Clean room, great staff, good breakfast."
United States
wallace
The price is 4.060.949 ₫
4.578.720 ₫ total
includes taxes & fees
3 Jul - 4 Jul
Hampton Inn Roxboro
Indoor pool

The Berry Hill Resort & Conference Center

The Berry Hill Resort & Conference Center
4.0 star property
19.9 km from Mayo Lake
9.2 out of 10, Wonderful, (736 reviews)
"The resort is in close proximity to Tunnel Creek and other nearby sites!"
United States
Miriam
The price is 3.551.850 ₫
4.412.187 ₫ total
includes taxes & fees
23 Jun - 24 Jun
The Berry Hill Resort & Conference Center
Miscellaneous

Charles Bass House Bed & Breakfast

Charles Bass House Bed & Breakfast
2.5 star property
20 km from Mayo Lake
9.8 out of 10, Exceptional, (108 reviews)
"Great host, quiet and calm environment and great breakfast "
United States
Joe
The price is 4.630.560 ₫
5.176.967 ₫ total
includes taxes & fees
17 Jun - 18 Jun
Charles Bass House Bed & Breakfast
Boating

Clarion Pointe South Boston - Danville East

Clarion Pointe South Boston - Danville East
3.5 star property
17.7 km from Mayo Lake
7.2 out of 10, Good, (322 reviews)
"Staff was very nice and helpful"
United States
Warren
The price is 2.581.011 ₫
2.885.571 ₫ total
includes taxes & fees
28 Jun - 29 Jun
Clarion Pointe South Boston - Danville East
Room, 1 King Bed, Accessible, Non Smoking (Efficiency) | Bathroom | Combined shower/bathtub, free toiletries, hair dryer, towels

Quality Inn - Roxboro South

Quality Inn - Roxboro South
2.5 star property
19.3 km from Mayo Lake
7.6 out of 10, Good, (477 reviews)
"The rooms were clean and the staff was very friendly. Our stay was enjoyable."
United States
Gayle
The price is 2.817.801 ₫
3.177.070 ₫ total
includes taxes & fees
20 Jun - 21 Jun
Quality Inn - Roxboro South
Free daily continental breakfast

Quality Inn South Boston - Danville East

Quality Inn South Boston - Danville East
2.5 star property
18.7 km from Mayo Lake
7.2 out of 10, Good, (403 reviews)
"The room smelled musty."
United States
David
The price is 2.303.441 ₫
2.575.247 ₫ total
includes taxes & fees
8 Jul - 9 Jul
Quality Inn South Boston - Danville East
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Compare popular hotels close to Mayo Lake

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Desk, blackout curtains, rollaway beds, free WiFi
Super 8 by Wyndham South Boston VA
2.0 star property
6.8
481 reviews
View
Blackout curtains, iron/ironing board, cots/infant beds, rollaway beds
Americas Best Value Inn Roxboro
2.0 star property
6.6
91 reviews
View
Reception
Budget Inn Roxboro
2.0 star property
6.4
170 reviews
View
Lobby
Americas Best Value Inn & Suites South Boston
2.0 star property
5.6
368 reviews
View
Free daily buffet breakfast
Fairfield Inn & Suites South Boston
3.0 star property
8.8
Excellent
406 reviews
View

Top Mayo Lake Hotel Reviews

Hampton Inn Roxboro

Hampton Inn Roxboro

2/10 Terrible
"Great day, on last evening June 12,2026, I woke to an itchy feeling on my back, arms and legs. I immediately got up. I pulled the cover back. I then pulled the cover back and seen the first bedbug not sure at the time what it was I smashed it , making a red bloody mark. I began moving the pillow and covers and discovered little black bugs crawling on the sheets and pillows. I immediately called the front desk, informed the worker. he then changed my room. My stay was behind uncomfortable. I got no sleep and I had to put my luggage and carrying bags in trash bags to get them home. I also had to go to urgent care this morning to get something to relieve the itching. I am so upset. I visit the area often. Over the 2-3 years I had only stayed at Quality Inn next door. I had to stay here at Hampton Inn/by Hilton, because Quality Inn was full. I will never stay here again. Yes there is remodeling being done, is it because you are updating the hotel well with the bedbugs,Remodeling is not enough."
Gertrude 1-night trip
Posted 12 hours ago
Hampton Inn Roxboro

Hotels near other Mayo Lake attractions

Person County Museum

5.0/5 (4 reviews)
You can spend an afternoon exploring the galleries in Person County Museum during your trip to Roxboro. Wander the lakeside in this family-friendly area.
See properties

Frequently asked questions

What's the area like around Mayo Lake?
Mayo Lake is located in Roxboro. You'll find 5 hotels and other accommodations within a few miles for a convenient home base.
How many hotels will I find near Mayo Lake?
Expedia has 5 hotels and other accommodation options a few miles from Mayo Lake.
If I need to cancel the hotel reservation for my stay near Mayo Lake, will I receive a refund?
Yes, you'll find most room reservations are refundable provided that you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you have a reservation that's non-refundable, you might still have the option to cancel and be given a refund within a 24-hour period of your booking. Add your dates and click on "Search", then filter by "fully refundable" to get the best options available near Mayo Lake.