Default HTG hotel image

Search Hotels in Medical Center, Detroit

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
4 Sep - 6 Sep
Next weekend
11 Sep - 13 Sep

Filter by

Star rating

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Our top choices for Medical Center hotels

Premium bedding, in-room safe, desk, laptop workspace

1. Hollywood Casino at Greektown

Hollywood Casino at Greektown
4.0 star property
Greektown Historic District, 2.4 km from Medical Center
8.6 out of 10, Excellent, (5,638 reviews)
"Fantastic stay as always"
United States
Rachel
The price is 4.224.401 ₫
5.626.057 ₫ total
includes taxes & fees
20 Sept - 21 Sept
Hollywood Casino at Greektown
4 bars/lounges

2. MotorCity Casino Hotel

MotorCity Casino Hotel
4.5 star property
North Corktown, 2 km from Medical Center
8.8 out of 10, Excellent, (4,746 reviews)
"Lovely place, enjoyed our stay very much"
United States
Donald
The price is 4.411.094 ₫
5.116.868 ₫ total
includes taxes & fees
1 Sept - 2 Sept
MotorCity Casino Hotel
Lobby

3. Atheneum Suite Hotel

Atheneum Suite Hotel
4.0 star property
Greektown Historic District, 2.5 km from Medical Center
9.2 out of 10, Wonderful, (2,412 reviews)
"Clean room, nice restaurant/bar area, great architecture and design to the property."
United States
Ryan
The price is 3.966.464 ₫
4.601.098 ₫ total
includes taxes & fees
1 Sept - 2 Sept
Atheneum Suite Hotel
Check-in/check-out kiosk

4. The Siren Hotel, an Ash Hotel

The Siren Hotel, an Ash Hotel
4.0 star property
Downtown Detroit, 2.2 km from Medical Center
9.0 out of 10, Wonderful, (2,152 reviews)
"Had a great stay. Was close to everything we came in town for would stay there again"
United States
Daniel
The price is 4.678.654 ₫
5.286.532 ₫ total
includes taxes & fees
8 Sept - 9 Sept
The Siren Hotel, an Ash Hotel
Breakfast, lunch and dinner served

5. Fort Pontchartrain Detroit, a Wyndham Hotel

Fort Pontchartrain Detroit, a Wyndham Hotel
3.5 star property
Downtown Detroit, 3.1 km from Medical Center
8.8 out of 10, Excellent, (2,312 reviews)
"Great stay"
United States
Jessica
The price is 3.746.105 ₫
4.345.482 ₫ total
includes taxes & fees
20 Sept - 21 Sept
Fort Pontchartrain Detroit, a Wyndham Hotel
Business centre

6. The Inn on Ferry Street

The Inn on Ferry Street
3.5 star property
1.2 km from Medical Center
8.4 out of 10, Very good, (243 reviews)
"Loved our stay here!"
United States
cassidy
The price is 3.879.102 ₫
4.848.226 ₫ total
includes taxes & fees
2 Sept - 3 Sept
The Inn on Ferry Street
7 restaurants; breakfast, lunch and dinner served

7. MGM Grand Detroit

MGM Grand Detroit
4.5 star property
Downtown Detroit, 2.4 km from Medical Center
8.4 out of 10, Very good, (1,064 reviews)
"Great staff and exceptionally clean rooms and property"
United States
Eric
The price is 5.189.522 ₫
6.745.858 ₫ total
includes taxes & fees
7 Sept - 8 Sept
MGM Grand Detroit
Exterior

8. Trumbull and Porter Hotel

Trumbull and Porter Hotel
3.5 star property
Corktown, 3.2 km from Medical Center
8.4 out of 10, Very good, (1,322 reviews)
"Friendly staff, clean rooms, easy parking"
United States
David W
The price is 3.025.048 ₫
3.418.304 ₫ total
includes taxes & fees
8 Sept - 9 Sept
Trumbull and Porter Hotel
Lobby

9. Comfort Inn Detroit Downtown

Comfort Inn Detroit Downtown
2.5 star property
Elmwood Park, 3.1 km from Medical Center
7.2 out of 10, Good, (1,006 reviews)
"Breakfast was really good...plenty to choose from. The manager was super friendly when we checked in and was pleasantly surprised when she informed me of the shuttle service."
United States
Nancy
The price is 2.411.693 ₫
2.680.506 ₫ total
includes taxes & fees
21 Sept - 22 Sept
Comfort Inn Detroit Downtown
Desk, blackout curtains, soundproofing, iron/ironing board

10. SpringHill Suites by Marriott Detroit Dearborn

SpringHill Suites by Marriott Detroit Dearborn
3.0 star property
13.3 km from Medical Center
8.8 out of 10, Excellent, (868 reviews)
"It was a great hotel"
Canada
Francesca
The price is 3.145.007 ₫
3.506.683 ₫ total
includes taxes & fees
7 Sept - 8 Sept
SpringHill Suites by Marriott Detroit Dearborn
2 restaurants; breakfast, lunch, dinner and brunch served

11. Cambria Hotel Detroit Downtown

Cambria Hotel Detroit Downtown
4.0 star property
Downtown Detroit, 2.8 km from Medical Center
9.4 out of 10, Exceptional, (1,352 reviews)
"Was a nice a great hotel vibes were amazing"
United States
Jonathan
The price is 3.966.464 ₫
4.620.931 ₫ total
includes taxes & fees
20 Sept - 21 Sept
Cambria Hotel Detroit Downtown
Terrace/patio

12. Holiday Inn Express & Suites Allen Park by IHG

Holiday Inn Express & Suites Allen Park by IHG
2.5 star property
16.5 km from Medical Center
9.0 out of 10, Wonderful, (1,153 reviews)
"Great place to stay. Perfect for babies and toddlers that they had a crib for us."
United States
Rachel
The price is 2.946.814 ₫
3.285.699 ₫ total
includes taxes & fees
28 Sept - 29 Sept
Holiday Inn Express & Suites Allen Park by IHG
Exterior

13. Hilton Garden Inn Detroit Downtown

Hilton Garden Inn Detroit Downtown
3.0 star property
Downtown Detroit, 2.2 km from Medical Center
8.6 out of 10, Excellent, (1,005 reviews)
"The staff was amazing. The room was excellent and the beds were amazing. Id stay here again the next time i visit"
United States
Qwennata
The price is 4.255.408 ₫
4.936.274 ₫ total
includes taxes & fees
7 Sept - 8 Sept
Hilton Garden Inn Detroit Downtown
Egyptian cotton sheets, premium bedding, desk, laptop workspace

14. Hotel Indigo Detroit Downtown by IHG

Hotel Indigo Detroit Downtown by IHG
3.5 star property
Downtown Detroit, 2.6 km from Medical Center
8.4 out of 10, Very good, (1,373 reviews)
"Great Stay"
United States
Dawn
The price is 4.198.558 ₫
4.931.089 ₫ total
includes taxes & fees
3 Sept - 4 Sept
Hotel Indigo Detroit Downtown by IHG
2 restaurants; breakfast, lunch, dinner and brunch served

15. ROOST Detroit

ROOST Detroit
4.5 star property
Downtown Detroit, 2.4 km from Medical Center
9.8 out of 10, Exceptional, (988 reviews)
"gorgeous hotel and exceptional staff"
United States
Pamela
The price is 6.548.186 ₫
8.283.493 ₫ total
includes taxes & fees
10 Sept - 11 Sept
ROOST Detroit
Dinner served

16. The Detroit Club

The Detroit Club
4.0 star property
Downtown Detroit, 2.8 km from Medical Center
9.2 out of 10, Wonderful, (510 reviews)
"Gorgeous property, love this place."
United States
Gino
The price is 4.016.011 ₫
5.292.852 ₫ total
includes taxes & fees
2 Sept - 3 Sept
The Detroit Club
Front of property

17. Best Western Greenfield Inn

Best Western Greenfield Inn
3.0 star property
14.2 km from Medical Center
8.6 out of 10, Excellent, (1,244 reviews)
"Everyone on staff made us feel welcome and taken care of."
United States
Jay
The price is 2.671.952 ₫
3.072.745 ₫ total
includes taxes & fees
3 Sept - 4 Sept
Best Western Greenfield Inn
Restaurant

18. Detroit Foundation Hotel

Detroit Foundation Hotel
4.0 star property
Downtown Detroit, 3 km from Medical Center
9.4 out of 10, Exceptional, (1,006 reviews)
"Hotel is beatitiful."
United States
scott
The price is 6.067.829 ₫
7.074.440 ₫ total
includes taxes & fees
7 Sept - 8 Sept
Detroit Foundation Hotel
Exterior

19. Hyatt Place Detroit Royal Oak

Hyatt Place Detroit Royal Oak
3.0 star property
17 km from Medical Center
9.6 out of 10, Exceptional, (1,005 reviews)
"Would stay here again."
United States
Leesa
The price is 3.963.856 ₫
4.380.060 ₫ total
includes taxes & fees
7 Sept - 8 Sept
Hyatt Place Detroit Royal Oak
Lobby

20. La Quinta Inn & Suites by Wyndham Detroit Metro Airport

La Quinta Inn & Suites by Wyndham Detroit Metro Airport
3.0 star property
26.6 km from Medical Center
8.4 out of 10, Very good, (2,648 reviews)
"Clean place to stay by airport."
United States
Bradley
The price is 2.482.626 ₫
2.768.128 ₫ total
includes taxes & fees
8 Sept - 9 Sept
La Quinta Inn & Suites by Wyndham Detroit Metro Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Medical Center

Find the best Medical Center areas for the activities you enjoy most.
A city skyline at dusk with reflections on the water.

Downtown Detroit

Known for its great live music and first-class casinos, there's plenty to explore in Downtown Detroit. Check out top attractions like Comerica Park and Ford Field, and jump on the metro at Campus Martius Station or Cadillac Center Station to see more of the city.

A historic building with a prominent corner turret, brick facade, and a well-maintained garden with colorful flowers.
Photo by Jw
Open Photo by Jw

Rochester Hills

Live music, restaurants and shopping are some highlights of Rochester Hills. Make a stop by The Village Of Rochester Hills or Meadow Brook Amphitheatre while you're exploring.

A cityscape with tall buildings, a statue, and autumn trees.

Midtown

If you're spending time in Midtown, check out sights like Little Caesars Arena or The Majestic Theatre and hop on the metro to see more of the city at Canfield Street Station or Martin Luther King Boulevard/Mack Avenue Station.

A tall, historic building with many windows and a classical architectural style.

Corktown

You'll enjoy the live music and historical sites in Corktown. You might want to make time for a stop at Michigan Central or PJ's Lager House.

A church with a tall spire and arched windows.
Photo by Terry Fletcher
Open Photo by Terry Fletcher

Brush Park

Brush Park might not have many top sights, but Little Caesars Arena and Comerica Park are two attractions nearby that you can check out.

Top Medical Center Hotel Reviews

Cambria Hotel Detroit Downtown

Cambria Hotel Detroit Downtown

10/10 Excellent
"Services were great and beautiful place to stay"
Joseph 1-night trip
Posted 3 hours ago
Cambria Hotel Detroit Downtown

Frequently asked questions

What's it like in Medical Center?
Travellers to the Medical Center neighbourhood in Detroit will be sure to enjoy their stay. Make sure that you visit Cultural Center Historic District and Lexus Velodrome as part of your Medical Center travel plans.
If I need to cancel my hotel reservation in Medical Center, will I receive a refund?
Yes, most room reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of check in. If you booked a non-refundable reservation, you might be able to cancel it and receive a refund within 24 hours of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to view the best deals in Medical Center.
What is there to do in this Detroit neighbourhood?
A few attractions you might want to check out while you're in Medical Center are Cultural Center Historic District and Lexus Velodrome. Little Caesars Arena and Comerica Park are also worth a visit when you're out sightseeing in Detroit.