The Best Hotels in Medical District, Greenville - 2026 Updated Prices

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Our top choices for Medical District hotels

A Courtyard by Marriott hotel with a covered entrance, outdoor seating, and a landscaped area.

1. Courtyard Marriott Greenville

Medical District

Wanda

3.716.684 ₫ total

includes taxes & fees

7 Oct - 8 Oct

A modern hotel room with a large bed, a desk with a chair, a flat-screen TV mounted on the wall, and a wardrobe.

2. Holiday Inn Express Greenville by IHG

0.9 km from Medical District

Tim

3.374.802 ₫ total

includes taxes & fees

28 Oct - 29 Oct

An indoor swimming pool with clear markings, a "NO DIVING" sign, and a view of parked cars outside.

3. Fairfield Inn & Suites by Marriott Greenville

0.9 km from Medical District

Frank

3.966.278 ₫ total

includes taxes & fees

3 Oct - 4 Oct

An outdoor patio area with a fire pit, seating, and umbrellas.

4. Residence Inn by Marriott Greenville

0.6 km from Medical District

Steve

3.492.320 ₫ total

includes taxes & fees

11 Oct - 12 Oct

A spacious lobby with a stone fireplace, comfortable seating, and a bar area.

5. Staybridge Suites Greenville Medical Center by IHG

0.8 km from Medical District

Ashly

3.345.715 ₫ total

includes taxes & fees

11 Oct - 12 Oct

A circular fire pit with seating around it, a covered patio area, and a brick building in the background.

6. Homewood Suites By Hilton Greenville, NC

0.7 km from Medical District

Telisa

2.984.027 ₫ total

includes taxes & fees

11 Oct - 12 Oct

A table set with glassware, plates, and cutlery, and a person arranging the table settings.

7. Holiday Inn Greenville by IHG

Convention District, 4.2 km from Medical District

Bridget

2.641.148 ₫ total

includes taxes & fees

28 Oct - 29 Oct

An outdoor patio with seating, a fire pit, and string lights.

8. Hilton Greenville

Convention District, 4.2 km from Medical District

Frederick

4.548.058 ₫ total

includes taxes & fees

18 Oct - 19 Oct

A multi-story hotel with a covered entrance, large windows, and a brick facade.

9. Microtel Inn & Suites by Wyndham Greenville/University Medic

0.6 km from Medical District

Richard

1.995.535 ₫ total

includes taxes & fees

11 Oct - 12 Oct

A spacious lobby with a blue sofa, yellow armchairs, a central coffee table, and a wooden balcony railing.

10. Comfort Inn & Suites Greenville Near East Carolina University

4 km from Medical District

Raymond

3.241.571 ₫ total

includes taxes & fees

11 Oct - 12 Oct

A modern hotel with a stone facade, large windows, and a well-lit entrance.

11. Hilton Garden INN Greenville University

Uptown Greenville, 2.9 km from Medical District

Darren

3.729.010 ₫ total

includes taxes & fees

18 Oct - 19 Oct

A modern dining area with a large window, a chandelier, and a patterned sofa.

12. Quality Inn Greenville near University

0.9 km from Medical District

Gerson

2.220.032 ₫ total

includes taxes & fees

20 Oct - 21 Oct

A hotel entrance with a sign reading 'Candlewood Suites.' There are potted plants and a mailbox in the foreground.

13. Candlewood Suites Greenville NC by IHG

2 km from Medical District

scott

2.729.292 ₫ total

includes taxes & fees

11 Oct - 12 Oct

A hotel room with a desk, two beds, a sofa, a TV, and a coffee machine.

14. Best Western Plus Suites-Greenville

6.5 km from Medical District

Teresa

3.356.900 ₫ total

includes taxes & fees

4 Oct - 5 Oct

An outdoor patio with seating, potted plants, and a brick fireplace.

15. Hampton Inn Greenville

Convention District, 4.1 km from Medical District

Rose

4.076.917 ₫ total

includes taxes & fees

4 Oct - 5 Oct

A hotel room with two beds, a red armchair, a sofa, and a desk.

16. Country Inn & Suites by Radisson, Greenville, NC

5.8 km from Medical District

Letitia

2.727.352 ₫ total

includes taxes & fees

11 Oct - 12 Oct

A hotel entrance with a prominent 'Super 8' sign, brick facade, and potted plants.

17. Super 8 by Wyndham Greenville

1.1 km from Medical District

Sharlene

2.170.144 ₫ total

includes taxes & fees

4 Oct - 5 Oct

A hotel room with two beds, each with patterned bedding, a bedside table with a lamp, and a framed picture on the wall.

18. Motel 6 Greenville, NC – ECU-Medical Center

0.8 km from Medical District

Renee

2.141.971 ₫ total

includes taxes & fees

1 Oct - 2 Oct

A spacious lobby with a high ceiling, a large window, a ceiling fan, a brown leather sofa, a glass coffee table with flowers, a patterned rug, and a red carpet.

19. Econo Lodge Greenville near University

0.8 km from Medical District

Gerardo

2.230.889 ₫ total

includes taxes & fees

1 Oct - 2 Oct

A clean, well-lit room with a tiled floor, a counter with a cash register, and a sign detailing room rates and policies.

20. Economy Inn of Greenville, NC

0.7 km from Medical District

David

1.663.924 ₫ total

includes taxes & fees

25 Oct - 26 Oct

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Where to stay in Medical District

Find the best Medical District areas for the activities you enjoy most.

A cityscape with a mix of modern and older buildings, a highway, and distant mountains.

Uptown Greenville

While visiting Uptown Greenville, you might make a stop by sights like Greenville Museum of Art and Town Common.

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University District

While University District isn't home to many top sights, Town Common and Dowdy–Ficklen Stadium are some notable places to visit nearby.

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Convention District

When in Convention District, you can plan a visit to University Commons and 11 Galleria, some noteworthy sights in the nearby area.

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Westhaven

Westhaven might not have many top sights, but 11 Galleria and Williams Arena at Minges Coliseum are two attractions nearby that you can check out.

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A cityscape with a dense forest in the foreground and a clear blue sky.

College View Historic District

If you're looking for some top things to see and do in College View Historic District and surrounding area, you can visit Williams Arena at Minges Coliseum and Dowdy–Ficklen Stadium.

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Top Medical District Hotel Reviews

Homewood Suites By Hilton Greenville, NC

10/10 Excellent

"Front desk manager, gentleman with the dreads, was amazing. Super nice, always greeted us as we came and went,"

Staybridge Suites Greenville Medical Center by IHG

10/10 Excellent

"I don’t expect much from hotels anymore that’s why I so pleasantly surprised by our stay. Excellent check in, thorough, professional. Loved loved loved the social on a Monday evening. Who gives you dinner, free beer and wine, and home baked cookies. Rooms were huge with full kitchen, living room, office space, 2 queens and a large bath. Everything was modern and spotless. Linens were new and clean, beds were great and breakfast was outstanding. This is what hotels should strive to provide! Job well done by everyone!"

Country Inn & Suites by Radisson, Greenville, NC

8/10 Good

"The hotel front desk - Chance was super nice and friendly. The breakfast bar attendant - Millie, was very nice and Millie kept the breakfast bar full and clean. Mille would assist guests as needed, such as making their waffles for them and even taking the finished waffle to the guest. The breakfast bar had a nice variety of items to choose from. One side note: there needs to be a sign or something to let other guests know this a "shared" breakfast bar and they should not hog the whole bar by spacing their chosen items all along the bar and blocking other guests from utilizing it. This was a repeated numerous times by the same set of guests. The housekeeping was whole different story for us. While they were friendly when we talked to them and were accommodating in providing towels. However, the whole time we were there, 3 days, our room was never cleaned. I check when we arrived to verify there was daily housekeeping and new towels each day. The used/wet towels were never removed, the trash cans were never emptied and the beds were never straighten up. We did not request for them "not" to do the normal housekeeping. Upon check-out this was brought to the front desk as an issue. Definitely not what I would and have expected from this brand."

Frequently asked questions

What is Medical District like?

Travellers are sure to enjoy a stay in Greenville's Medical District neighbourhood. Consider a visit to Laupus Health Sciences Library as part of your Medical District travel plans.

If I need to cancel my hotel reservation in Medical District, will I receive a refund?

Yes, most hotel room reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your arrival date. If you booked a non-refundable reservation, you might be able to still cancel and receive a refund within a 24-hour period of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to review the best deals available in Medical District.

What can I see and do in this Greenville neighbourhood?

Laupus Health Sciences Library is an attraction you might want to check out while you're in Medical District. When you're sightseeing in Greenville, North Pines and Guy Smith Stadium are also worth a stop.

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Our top choices for Medical District hotels

1. Courtyard Marriott Greenville

2. Holiday Inn Express Greenville by IHG

3. Fairfield Inn & Suites by Marriott Greenville

4. Residence Inn by Marriott Greenville

5. Staybridge Suites Greenville Medical Center by IHG

6. Homewood Suites By Hilton Greenville, NC

7. Holiday Inn Greenville by IHG

8. Hilton Greenville

9. Microtel Inn & Suites by Wyndham Greenville/University Medic

10. Comfort Inn & Suites Greenville Near East Carolina University

11. Hilton Garden INN Greenville University

12. Quality Inn Greenville near University

13. Candlewood Suites Greenville NC by IHG

14. Best Western Plus Suites-Greenville

15. Hampton Inn Greenville

16. Country Inn & Suites by Radisson, Greenville, NC

17. Super 8 by Wyndham Greenville

18. Motel 6 Greenville, NC – ECU-Medical Center

19. Econo Lodge Greenville near University

20. Economy Inn of Greenville, NC

Where to stay in Medical District

Uptown Greenville

University District

Convention District

Westhaven

College View Historic District

Top Medical District Hotel Reviews

Homewood Suites By Hilton Greenville, NC

Frequently asked questions

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