Search Casino Hotels in Mesquite

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Mesquite Casino Hotels

Our top choices for Mesquite hotels with a casino

Interior detail
Virgin River Hotel and Casino

Virgin River Hotel and Casino

Virgin River Hotel and Casino
2.5 star property
Mesquite
8.2 out of 10, Very good, (8273)
"nice place to stay"
United States
Dustin
The price is 1.108.977 ₫
1.247.599 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Virgin River Hotel and Casino
Casino
Eureka Casino Resort

Eureka Casino Resort

Eureka Casino Resort
3.0 star property
Mesquite
8.8 out of 10, Excellent, (1615)
"Outstanding accommodations clean comfortable "
United States
Ralph
The price is 2.502.308 ₫
3.199.763 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Eureka Casino Resort
Reception
Holiday Inn Resort Mesquite by IHG

Holiday Inn Resort Mesquite by IHG

Holiday Inn Resort Mesquite by IHG
3.0 star property
Mesquite
8.2 out of 10, Very good, (999)
"Well-maintained and lovely stay. "
United States
April
The price is 2.185.307 ₫
2.721.497 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Holiday Inn Resort Mesquite by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Mesquite Hotel Reviews

Virgin River Hotel and Casino

Virgin River Hotel and Casino

10/10 Excellent
"Yes"
randy 3-night trip
Posted 3 days ago
Virgin River Hotel and Casino
CasaBlanca Resort and Casino

CasaBlanca Resort and Casino

10/10 Excellent
"Room was clean "
Darlene 3-night trip
Posted 11 days ago
CasaBlanca Resort and Casino

Explore a world of travel with Expedia

Frequently asked questions

Searching for casino hotels in Mesquite?
If you're planning a gaming trip to Mesquite, you can roll the dice at Virgin River Casino and Eureka Casino, though they aren't the only places worth visiting while you're in town. Tourists speak highly of the golf courses, bowling and abundant cafes.
How many hotels that are good for gaming will I be able to find in Mesquite?
Hit the casinos and have a good night's sleep at one of Expedia's 238 hotels in Mesquite.
When should I take my casino trip to Mesquite?
You'll likely spend much of your trip indoors, but if you're planning to venture beyond the casino, looking at local weather trends is a good idea. The hottest months are usually July and August, with an average temperature of 31°C, while the coldest months are January and December, with an average of 9°C. Average annual precipitation for Mesquite is 165 mm.
What is there to do in Mesquite?
Mesquite is known for its entertainment venues, and you can visit cultural spots such as Virgin Valley Heritage Museum. Nature enthusiasts will appreciate the riverfront, and places to get outdoors include Vernon Worthen Park and Virgin River Gorge. In addition, you might want to add Virgin River Casino and Wolf Creek Golf Club to your list.