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Search Hotels in Middletown, San Diego

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Our top choices for Middletown hotels

City24 Hotel Little Italy Mission Hills

City24 Hotel Little Italy Mission Hills
4.5 star property
Middletown
9.6 out of 10, Exceptional, (107)
"would definitely go back and stay there again "
United States
Kounwick
City24 Hotel Little Italy Mission Hills

Comfort Inn San Diego Old Town

Comfort Inn San Diego Old Town
2.5 star property
Old Town San Diego, 2.1 km from Middletown
8.2 out of 10, Very good, (1919)
"Great stay "
United States
Vanessa
The price is 2.001.308 ₫
2.300.404 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Comfort Inn San Diego Old Town

The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection
3.0 star property
2.2 km from Middletown
8.8 out of 10, Excellent, (780)
"would stay again and recommend "
United States
Brendi
The price is 2.947.280 ₫
3.417.223 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
The DEXTRO Little Italy, BW Premier Collection

Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego
4.0 star property
Marina District, 3.4 km from Middletown
9.0 out of 10, Wonderful, (2881)
"Lovely hotel with friendly staff."
United States
Lynnea
The price is 3.976.283 ₫
6.045.187 ₫ total
includes taxes & fees
24 Dec - 25 Dec
Manchester Grand Hyatt San Diego

Staypineapple, Hotel Z, Gaslamp San Diego

Staypineapple, Hotel Z, Gaslamp San Diego
3.0 star property
Gaslamp Quarter, 3.6 km from Middletown
9.4 out of 10, Exceptional, (1006)
"Great location "
United States
Mohammad
The price is 2.346.270 ₫
3.481.406 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Staypineapple, Hotel Z, Gaslamp San Diego

Wyndham San Diego Bayside

Wyndham San Diego Bayside
4.0 star property
2.3 km from Middletown
8.4 out of 10, Very good, (6049)
"Always an amazing stay"
United States
Jana
The price is 3.556.472 ₫
4.886.687 ₫ total
includes taxes & fees
30 Dec - 31 Dec
Wyndham San Diego Bayside

Sheraton San Diego Resort

Sheraton San Diego Resort
4.0 star property
2.5 km from Middletown
8.4 out of 10, Very good, (3182)
"Great stay! "
United States
Melissa
The price is 3.243.324 ₫
4.675.379 ₫ total
includes taxes & fees
27 Dec - 28 Dec
Sheraton San Diego Resort

DoubleTree by Hilton San Diego - Del Mar

DoubleTree by Hilton San Diego - Del Mar
4.0 star property
Carmel Valley, 22.6 km from Middletown
8.4 out of 10, Very good, (1916)
"Excellent location"
United States
Paolo
The price is 2.569.574 ₫
2.927.901 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
DoubleTree by Hilton San Diego - Del Mar

Fairfield Inn & Suites by Marriott San Diego Pacific Beach

Fairfield Inn & Suites by Marriott San Diego Pacific Beach
2.5 star property
Pacific Beach, 7.8 km from Middletown
9.0 out of 10, Wonderful, (809)
"Good location, good basic breakfast, good parking, recommended. "
United States
Leyla
The price is 2.712.299 ₫
3.117.651 ₫ total
includes taxes & fees
3 Jan - 4 Jan 2026
Fairfield Inn & Suites by Marriott San Diego Pacific Beach

Best Western Plus Island Palms Hotel & Marina

Best Western Plus Island Palms Hotel & Marina
3.0 star property
5.7 km from Middletown
8.8 out of 10, Excellent, (1560)
"Staff was great, easy check in and great location"
United States
Alysa
The price is 2.928.230 ₫
3.365.855 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Best Western Plus Island Palms Hotel & Marina

Wyndham Garden San Diego Near SeaWorld

Wyndham Garden San Diego Near SeaWorld
3.0 star property
4.1 km from Middletown
7.4 out of 10, Good, (4117)
"Room was very clean and staff very pleasant "
Canada
Brian
The price is 2.342.035 ₫
2.692.052 ₫ total
includes taxes & fees
24 Dec - 25 Dec
Wyndham Garden San Diego Near SeaWorld

Hampton Inn San Diego-Downtown

Hampton Inn San Diego-Downtown
2.5 star property
2.1 km from Middletown
8.2 out of 10, Very good, (2300)
"Nice and convenient place to stay!"
United States
Esperanza
The price is 2.731.306 ₫
3.166.813 ₫ total
includes taxes & fees
18 Jan - 19 Jan 2026
Hampton Inn San Diego-Downtown

San Diego Mission Bay Resort

San Diego Mission Bay Resort
4.0 star property
Mission Bay, 5.4 km from Middletown
8.4 out of 10, Very good, (1312)
"Room was super clean and updated, location up against the bay was perfect. We really enjoyed our stay and want to come back soon!"
United States
Haley
The price is 3.875.147 ₫
5.640.883 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
San Diego Mission Bay Resort

Hilton San Diego Bayfront

Hilton San Diego Bayfront
4.0 star property
Marina District, 4.2 km from Middletown
8.6 out of 10, Excellent, (1888)
"Enjoyed my stay"
United States
Brandon
The price is 3.252.126 ₫
5.061.500 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Hilton San Diego Bayfront

Hard Rock Hotel San Diego

Hard Rock Hotel San Diego
4.0 star property
Gaslamp Quarter, 3.8 km from Middletown
9.0 out of 10, Wonderful, (3173)
"Nice hotel"
United States
Genelle
The price is 4.476.181 ₫
6.399.564 ₫ total
includes taxes & fees
24 Dec - 25 Dec
Hard Rock Hotel San Diego

Kings Inn San Diego

Kings Inn San Diego
2.5 star property
2.1 km from Middletown
8.8 out of 10, Excellent, (3581)
"Clean and the amenities were outstanding, the staff was polite and helpful 👍 "
United States
walter
Kings Inn San Diego

Marriott Marquis San Diego Marina

Marriott Marquis San Diego Marina
4.0 star property
Marina District, 3.5 km from Middletown
9.2 out of 10, Wonderful, (1958)
"Amazing hotel Superb view Friendly staff Clean and neat rooms "
United States
Chirag
The price is 4.451.182 ₫
6.544.306 ₫ total
includes taxes & fees
25 Dec - 26 Dec
Marriott Marquis San Diego Marina

DoubleTree by Hilton Hotel San Diego - Mission Valley

DoubleTree by Hilton Hotel San Diego - Mission Valley
4.0 star property
3.6 km from Middletown
8.4 out of 10, Very good, (1422)
"Great hotel in a great area - would definitely stay here again."
United States
Bhupinder
The price is 2.956.227 ₫
3.398.035 ₫ total
includes taxes & fees
3 Jan - 4 Jan 2026
DoubleTree by Hilton Hotel San Diego - Mission Valley

Paradise Point Resort & Spa

Paradise Point Resort & Spa
4.0 star property
Mission Bay, 7.1 km from Middletown
8.6 out of 10, Excellent, (2357)
"Great stay, top tier service and excellent customer care "
Canada
Meriem
The price is 3.406.174 ₫
5.308.733 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Paradise Point Resort & Spa

SureStay Hotel by Best Western San Diego Pacific Beach

SureStay Hotel by Best Western San Diego Pacific Beach
2.5 star property
Pacific Beach, 8.1 km from Middletown
8.0 out of 10, Very good, (1425)
"our stay was great and staff was supportive..."
United States
Ramesh
The price is 2.083.885 ₫
2.353.644 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
SureStay Hotel by Best Western San Diego Pacific Beach
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Middletown

Find the best Middletown areas for the activities you enjoy most.

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

Gaslamp Quarter

Cosy bars interesting history and top sights from Gaslamp Museum at the Davis-Horton House to Lyceum Theatre – discover Gaslamp Quarter, a destination also famous for its shopping.

Pacific Beach

The stunning beaches and fantastic nightlife are just a few highlights of Pacific Beach. Make a stop by Mission Bay or Tourmaline Surfing Park while you're exploring the area.

Mission Beach

If you're spending some time in Mission Beach, Mission Bay and Mission and Pacific Beaches are top sights worth seeing.

Ocean Beach

Ocean Beach is beloved for its stunning beaches. Take some time to explore sights in the area like Dog Beach and Sunset Cliffs Natural Park.

Top Middletown Hotel Reviews

Frequently asked questions

What's it like in Middletown?
Middletown is a neighbourhood that travellers like for its live music, bars and theatres.
How many hotels can I expect to find in the Middletown area?
Expedia has 91 hotels and other accommodation options in Middletown to choose from, making this an ideal home base for exploring the greater San Diego area.
If I need to cancel my hotel reservation in Middletown, will I receive a refund?
Yes! The majority of hotel reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of the scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of booking. Put your dates in and click on "Search", then use the "fully refundable" filter to view top deals in Middletown.
What are the top things to see and do in Middletown?
Favourite places to visit in the surrounding area include San Diego Zoo, Hotel Circle and Port of San Diego. While you're out sightseeing, Petco Park and Marston House are a couple of additional sights to visit in San Diego.
How can I get around Middletown and the greater San Diego area?
Ready to get out and explore the city? Middletown Station is the closest metro station.