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Check availability on Midtown East Business Hotels

Our top choices for Midtown East business-friendly hotels

Terrace/patio
Pod 39

Pod 39

Pod 39
3.0 star property
Manhattan
9.2 out of 10, Wonderful, (1580)
"Kind helpful staff, cozy room, comfortable bed, great shower."
United States
Jennifer
The price is 2.166.350 ₫
3.182.123 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Pod 39
Interior
Club Quarters Hotel, Grand Central

Club Quarters Hotel, Grand Central

Club Quarters Hotel, Grand Central
4.0 star property
Manhattan
9.0 out of 10, Wonderful, (2785)
"Staff were very friendly and helpful, and made us feel welcome. "
United States
Lee
The price is 5.502.761 ₫
7.161.884 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Club Quarters Hotel, Grand Central
Pool
Hyatt Grand Central New York

Hyatt Grand Central New York

Hyatt Grand Central New York
4.0 star property
Manhattan
8.2 out of 10, Very good, (6384)
"Great hotel and the bartenders in the hotel lobby restaurant and bar were phenomenal "
United States
Lance
The price is 5.461.170 ₫
7.568.465 ₫ total
includes taxes & fees
10 Jan - 11 Jan 2026
Hyatt Grand Central New York
Terrace/patio
Hotel 57

Hotel 57

Hotel 57
4.0 star property
Manhattan
8.2 out of 10, Very good, (1287)
"Great location, great room, great service, great value."
Canada
Vivek
The price is 3.452.258 ₫
5.262.118 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Hotel 57
Suite, 1 Bedroom (Balcony) | Balcony view
The Lexington Hotel, Autograph Collection

The Lexington Hotel, Autograph Collection

The Lexington Hotel, Autograph Collection
4.0 star property
Manhattan
8.2 out of 10, Very good, (1638)
"Amazing stay "
United States
Ivan
The price is 4.402.209 ₫
6.201.059 ₫ total
includes taxes & fees
3 Jan - 4 Jan 2026
The Lexington Hotel, Autograph Collection
Breakfast and dinner served
EVEN Hotel New York - Midtown East by IHG

EVEN Hotel New York - Midtown East by IHG

EVEN Hotel New York - Midtown East by IHG
4.0 star property
Manhattan
9.0 out of 10, Wonderful, (1586)
"Room was nice, location was great, would stay again!!"
United States
Rachel
The price is 3.212.138 ₫
4.684.325 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
EVEN Hotel New York - Midtown East by IHG
Presidential Suite, 1 King Bed | Bathroom | Eco-friendly toiletries, hair dryer, towels, soap
Millennium Hilton New York One UN Plaza

Millennium Hilton New York One UN Plaza

Millennium Hilton New York One UN Plaza
4.0 star property
Manhattan
8.2 out of 10, Very good, (1943)
"I enjoy my stay "
United States
Shana
The price is 3.142.366 ₫
4.755.390 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Millennium Hilton New York One UN Plaza
Luxe Queen Room | Egyptian cotton sheets, premium bedding, in-room safe, desk
Westgate New York Grand Central

Westgate New York Grand Central

Westgate New York Grand Central
4.0 star property
Manhattan
9.0 out of 10, Wonderful, (3063)
"Great place very nice hotel to stay at."
United States
David
The price is 3.334.791 ₫
4.976.197 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Westgate New York Grand Central
View from property
The Westin New York Grand Central

The Westin New York Grand Central

The Westin New York Grand Central
4.5 star property
Manhattan
9.0 out of 10, Wonderful, (3618)
"Great place to stay! "
United States
Moema Arruda-
The price is 4.976.181 ₫
6.610.357 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
The Westin New York Grand Central
Exterior
Hilton Garden Inn New York/Manhattan-Midtown East

Hilton Garden Inn New York/Manhattan-Midtown East

Hilton Garden Inn New York/Manhattan-Midtown East
3.5 star property
Manhattan
8.2 out of 10, Very good, (1529)
"Good experience , excellent location , perfect stay"
United States
Marielys
The price is 2.754.277 ₫
3.252.686 ₫ total
includes taxes & fees
6 Jan - 7 Jan 2026
Hilton Garden Inn New York/Manhattan-Midtown East
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Midtown East Hotel Reviews

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Frequently asked questions

Why book your business-friendly hotel in Midtown East with Expedia?
With handy amenities like meeting rooms, housekeeping and free WiFi, our business-friendly accommodation come with all you'll need to get the job done — and then relax! Enter your destination and travel dates and Expedia will help you with everything else.
How can I find cheap business-friendly hotels in Midtown East?
Click on the "business friendly" filter, located just under the "traveller experience" heading, to find cheap business-friendly hotels in Midtown East. Then refine your search by your nightly budget. Choosing a stay in a less popular neighbourhood can also help you save.