Search Business Hotels in Midtown East

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Midtown East Business Hotels

Our top choices for Midtown East business-friendly hotels

2 bars/lounges, rooftop bar
Pod 39

Pod 39

3.0 star property
Manhattan
9.2 out of 10, Wonderful, (1579)
"Kind helpful staff, cozy room, comfortable bed, great shower."
United States
Jennifer
The price is 2.169.724 ₫
3.187.079 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Pod 39
Interior
Club Quarters Hotel, Grand Central

Club Quarters Hotel, Grand Central

4.0 star property
Manhattan
9.0 out of 10, Wonderful, (2783)
"Great location, friendly staff and good amenities. "
United States
Mey Ling
The price is 6.355.170 ₫
8.141.341 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Club Quarters Hotel, Grand Central
Pool
Hyatt Grand Central New York

Hyatt Grand Central New York

4.0 star property
Manhattan
8.2 out of 10, Very good, (6402)
"Great stay! "
United States
Ashley
The price is 4.407.726 ₫
6.359.885 ₫ total
includes taxes & fees
8 Jan - 9 Jan 2026
Hyatt Grand Central New York
Exterior
Hotel 57

Hotel 57

4.0 star property
Manhattan
8.2 out of 10, Very good, (1280)
"Great location, great room, great service, great value."
Canada
Vivek
The price is 2.839.978 ₫
4.561.158 ₫ total
includes taxes & fees
6 Jan - 7 Jan 2026
Hotel 57
Suite, 1 Bedroom (Balcony) | In-room safe, desk, laptop workspace, blackout curtains
The Lexington Hotel, Autograph Collection

The Lexington Hotel, Autograph Collection

4.0 star property
Manhattan
8.2 out of 10, Very good, (1636)
"Amazing stay "
United States
Ivan
The price is 4.407.726 ₫
6.208.831 ₫ total
includes taxes & fees
3 Jan - 4 Jan 2026
The Lexington Hotel, Autograph Collection
Breakfast and dinner served
EVEN Hotel New York - Midtown East by IHG

EVEN Hotel New York - Midtown East by IHG

4.0 star property
Manhattan
9.0 out of 10, Wonderful, (1582)
"Great Room and amazing location!"
Mexico
Lucia
The price is 3.216.164 ₫
4.690.194 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
EVEN Hotel New York - Midtown East by IHG
View from property
The Westin New York Grand Central

The Westin New York Grand Central

4.5 star property
Manhattan
9.0 out of 10, Wonderful, (3626)
"Great place to stay! "
United States
Moema Arruda-
The price is 4.983.930 ₫
6.620.650 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
The Westin New York Grand Central
Penthouse, 1 Bedroom | Egyptian cotton sheets, premium bedding, in-room safe
The Shelburne Sonesta New York

The Shelburne Sonesta New York

4.0 star property
Manhattan
9.0 out of 10, Wonderful, (1871)
"Always a great midtown stay- amazing prices- love the rooftop restaurant & bar!"
United States
Jamie Marie
The price is 3.876.390 ₫
5.811.486 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
The Shelburne Sonesta New York
Luxe Queen Room | Egyptian cotton sheets, premium bedding, in-room safe, desk
Westgate New York Grand Central

Westgate New York Grand Central

4.0 star property
Manhattan
9.0 out of 10, Wonderful, (3059)
"Great place very nice hotel to stay at."
United States
David
The price is 3.788.275 ₫
5.498.360 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Westgate New York Grand Central
Exterior
Park South Hotel, part of JdV by Hyatt

Park South Hotel, part of JdV by Hyatt

4.0 star property
Manhattan
9.2 out of 10, Wonderful, (1005)
"Tremendous place, loved it"
United States
Eduardo
The price is 3.775.038 ₫
5.331.769 ₫ total
includes taxes & fees
6 Jan - 7 Jan 2026
Park South Hotel, part of JdV by Hyatt
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Midtown East Hotel Reviews

Explore a world of travel with Expedia

Frequently asked questions

Why book your business-friendly hotel in Midtown East with Expedia?
With handy amenities like meeting rooms, housekeeping and free WiFi, our business-friendly accommodation come with all you'll need to get the job done — and then relax! Enter your destination and travel dates and Expedia will help you with everything else.
How can I find cheap business-friendly hotels in Midtown East?
Click on the "business friendly" filter, located just under the "traveller experience" heading, to find cheap business-friendly hotels in Midtown East. Then refine your search by your nightly budget. Choosing a stay in a less popular neighbourhood can also help you save.