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Search Hotels in Mission District, San Francisco

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Check prices for these dates

Next weekend
23 Oct - 25 Oct
In two weeks
30 Oct - 1 Nov

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Our top choices for Mission District hotels

A wooden outdoor bar set with a variety of snacks, wine glasses, and bottles in a bucket.

1. Parker Guest House San Francisco

Parker Guest House San Francisco
3.5 star property
Mission District
9.6 out of 10, Exceptional, (508 reviews)
"Great location and breakfast"
United States
Tom
The price is 5.924.917 ₫
6.903.175 ₫ total
includes taxes & fees
4 Nov - 5 Nov
Parker Guest House San Francisco
A wooden deck with a table set for two, featuring a plate of food and a cup of coffee.

2. Noe's Nest Bed and Breakfast

Noe's Nest Bed and Breakfast
3.5 star property
Mission District
9.4 out of 10, Exceptional, (136 reviews)
"Everything was great. Beds were comfortable and we had a great back yard view and balcony we enjoyed greatly. The breakfast was excellent first two days and became OK the next two days! I will definitely try to stay there on my future SF visits."
United States
Ali
The price is 6.985.710 ₫
8.125.255 ₫ total
includes taxes & fees
20 Oct - 21 Oct
Noe's Nest Bed and Breakfast
A hallway with a wooden ceiling, a table with chairs, a potted plant, and framed pictures on the walls.

3. 1906 Mission

1906 Mission
2.0 star property
Mission District
7.8 out of 10, Good, (213 reviews)
"It was educational..."
United States
Arianne
The price is 2.354.443 ₫
2.738.398 ₫ total
includes taxes & fees
8 Nov - 9 Nov
1906 Mission
A multi-story building with a corner entrance, a massage parlor, and a hotel named 'Hotel Sunrise' with a red awning.

4. Hotel Sunrise

Hotel Sunrise
2.0 star property
Mission District
6.8 out of 10, (696 reviews)
"Great stay for the price. Coukd g"
United States
Joseph
The price is 2.302.697 ₫
2.678.325 ₫ total
includes taxes & fees
1 Nov - 2 Nov
Hotel Sunrise
A single bed with a white pillow and a mustard-colored blanket.

5. Union Hotel

Union Hotel
2.0 star property
Mission District
7.0 out of 10, Good, (323 reviews)
"Great food located all within walking distance of the front door!"
United States
Patricio
The price is 1.397.142 ₫
1.627.929 ₫ total
includes taxes & fees
25 Oct - 26 Oct
Union Hotel
A rooftop pool area with blue seating and a pool.

6. Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG
3.5 star property
Nob Hill, 3.4 km from Mission District
9.0 out of 10, Wonderful, (6,414 reviews)
"Very good location & hotel"
United States
Sebastian Pablo
The price is 3.492.855 ₫
4.110.961 ₫ total
includes taxes & fees
8 Nov - 9 Nov
Holiday Inn Golden Gateway by IHG
A modern hotel lobby with a seating area, a bar, and large windows.

7. Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf
4.0 star property
Fisherman's Wharf, 5.4 km from Mission District
9.0 out of 10, Wonderful, (7,719 reviews)
"Great location, breakfast was excellent."
Canada
Richard
The price is 2.907.208 ₫
4.487.606 ₫ total
includes taxes & fees
9 Nov - 10 Nov
Hotel Riu Plaza Fisherman's Wharf
A hotel room with a large bed, a TV, a desk, and a view of a cityscape at sunset.

8. Parc 55 San Francisco - A Hilton Hotel

Parc 55 San Francisco - A Hilton Hotel
4.0 star property
Union Square, 2.9 km from Mission District
8.8 out of 10, Excellent, (1,701 reviews)
"Really great area to stay!"
United States
Janet
The price is 3.797.639 ₫
4.469.630 ₫ total
includes taxes & fees
7 Nov - 8 Nov
Parc 55 San Francisco - A Hilton Hotel
A spacious lobby with large windows, a seating area with a sofa and chairs, and a counter with a coffee station.

9. LUMA Hotel San Francisco

LUMA Hotel San Francisco
4.0 star property
2.9 km from Mission District
9.6 out of 10, Exceptional, (2,632 reviews)
"Great location and comfortable beds"
United States
Heather
The price is 6.600.675 ₫
7.768.865 ₫ total
includes taxes & fees
6 Nov - 7 Nov
LUMA Hotel San Francisco
An indoor swimming pool with multiple lounge chairs and a high ceiling with skylights.

10. Hotel Nikko San Francisco

Hotel Nikko San Francisco
4.5 star property
Union Square, 3 km from Mission District
9.4 out of 10, Exceptional, (3,129 reviews)
"Great hotel!"
United States
Isaac
The price is 4.818.493 ₫
6.861.596 ₫ total
includes taxes & fees
30 Oct - 31 Oct
Hotel Nikko San Francisco
A lobby with seating, a reception desk, and large windows.

11. Chancellor Hotel on Union Square

Chancellor Hotel on Union Square
3.5 star property
3.3 km from Mission District
9.4 out of 10, Exceptional, (3,516 reviews)
"Great location, nice hotel"
United States
eric
The price is 3.085.491 ₫
3.638.395 ₫ total
includes taxes & fees
18 Oct - 19 Oct
Chancellor Hotel on Union Square
An outdoor seating area with wicker furniture and a fire feature, adjacent to a bar and dining area with modern decor.

12. Hyatt Place San Francisco Downtown

Hyatt Place San Francisco Downtown
3.0 star property
3 km from Mission District
9.4 out of 10, Exceptional, (2,360 reviews)
"Loved staying here"
United States
Morgan
The price is 5.047.575 ₫
5.940.743 ₫ total
includes taxes & fees
6 Nov - 7 Nov
Hyatt Place San Francisco Downtown
A modern hotel with a sleek exterior and a parked sports car in front.

13. Hotel VIA

Hotel VIA
4.0 star property
3.2 km from Mission District
9.2 out of 10, Wonderful, (1,572 reviews)
"Amazing stay"
United States
Gabriela
The price is 5.101.934 ₫
6.004.722 ₫ total
includes taxes & fees
6 Nov - 7 Nov
Hotel VIA
A hotel room with two beds, a wooden accent wall, a ceiling fan, and a large window with curtains.

14. Hotel 32One

Hotel 32One
3.0 star property
Union Square, 3.5 km from Mission District
8.8 out of 10, Excellent, (977 reviews)
"Great for a one night stay in between flights!"
United States
Isaac
The price is 3.648.610 ₫
4.293.883 ₫ total
includes taxes & fees
8 Nov - 9 Nov
Hotel 32One
A hotel room with a bed, a sofa, a small table, a chair, and a desk.

15. Symphony Inn

Symphony Inn
2.5 star property
2.1 km from Mission District
8.8 out of 10, Excellent, (1,286 reviews)
"Great location!"
United States
zack
The price is 3.471.178 ₫
4.044.183 ₫ total
includes taxes & fees
1 Nov - 2 Nov
Symphony Inn
A hotel room with a large bed, a desk with a chair, a TV, and a view of the city.

16. Comfort Inn by the Bay

Comfort Inn by the Bay
2.5 star property
Cow Hollow, 4.7 km from Mission District
8.4 out of 10, Very good, (1,730 reviews)
"Staff was very friendly and great value for the cost."
United States
Diane
The price is 3.189.032 ₫
3.753.331 ₫ total
includes taxes & fees
9 Nov - 10 Nov
Comfort Inn by the Bay
A grand lobby with high ceilings, chandeliers, and a fireplace.

17. The Marker Union Square San Francisco

The Marker Union Square San Francisco
4.0 star property
3.1 km from Mission District
9.2 out of 10, Wonderful, (1,587 reviews)
"Great place to stay!"
Canada
Samantha
The price is 4.139.011 ₫
4.871.409 ₫ total
includes taxes & fees
30 Oct - 31 Oct
The Marker Union Square San Francisco
A high-rise room with a city view, a sofa, two chairs, a small table, and a patterned rug.

18. Hilton San Francisco Union Square

Hilton San Francisco Union Square
4.0 star property
Union Square, 3 km from Mission District
8.6 out of 10, Excellent, (1,805 reviews)
"The breakfast was good and the hotel was clean."
United States
Dusan
The price is 4.077.405 ₫
4.798.902 ₫ total
includes taxes & fees
6 Nov - 7 Nov
Hilton San Francisco Union Square
A rooftop terrace with a table and chairs, a potted plant, and a view of tall buildings.

19. Club Quarters Hotel Embarcadero, San Francisco

Club Quarters Hotel Embarcadero, San Francisco
4.0 star property
Financial District, 4.2 km from Mission District
8.8 out of 10, Excellent, (3,513 reviews)
"Great Stay"
United States
Russell
The price is 3.777.458 ₫
4.445.879 ₫ total
includes taxes & fees
25 Oct - 26 Oct
Club Quarters Hotel Embarcadero, San Francisco
A restaurant interior with wooden tables and booths, a tiled pillar, and a unique ceiling design.

20. Hotel G San Francisco

Hotel G San Francisco
4.0 star property
3.2 km from Mission District
9.2 out of 10, Wonderful, (1,006 reviews)
"Great location, excellent staff."
United States
matthew
The price is 3.475.061 ₫
5.125.795 ₫ total
includes taxes & fees
18 Oct - 19 Oct
Hotel G San Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Mission District

Find the best Mission District areas for the activities you enjoy most.
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Union Square

Known for its charming cafes and popular shops, there's plenty to explore in Union Square. Check out top attractions like Westin St Francis Hotel Glass Elevators and Union Square, and jump on the metro at Powell St & Geary Blvd Stop or Powell St & Post St Stop to see more of the city.

A trolley on a street with buildings and a clock tower.

Downtown San Francisco

Known for its fascinating museums, popular shops and acclaimed art galleries, there's plenty to explore in Downtown San Francisco. Top attractions like Oracle Park and Chase Center are major draws. Catch the metro at Market St & 5th St Stop or Market St & Taylor St Stop to see more of the city.

A pier with a large number of sea lions resting on floating platforms.

Fisherman's Wharf

Travellers love Fisherman's Wharf for its popular shops, and you can see more of San Francisco by jumping on the metro at Jones St and Beach St Stop or Jefferson St & Taylor St Stop. You might spend time checking out top sights like Pier 39 and San Francisco Bay.

A city street with tall buildings, flags, and cars.

South of Market

Gourmet restaurants great entertainment and top sights from Oracle Park to Chase Center – discover South of Market, a destination also famous for its shopping.

A cityscape with a prominent skyscraper, a bridge, and a mix of modern and historic buildings.

Nob Hill

Gourmet restaurants Chinatown and top sights from SF Masonic Auditorium to Cable Car Museum – discover Nob Hill, a destination also famous for its shopping.

Top Mission District Hotel Reviews

Hotel Zephyr San Francisco

Hotel Zephyr San Francisco

10/10 Excellent
"Great location and fun vibe! Would stay here again!"
Elisa 1-night trip
Posted 2 hours ago
Hotel Zephyr San Francisco

Frequently asked questions

What is Mission District like?
Mission District is a neighbourhood that travellers like for its bars. Are you looking for Mission District travel tips? Make sure that you visit SOMA Pilipinas and The Chapel while you're in the neighbourhood.
How many hotels will I be able to find in the Mission District area?
Expedia has 66 hotels and other accommodation options in Mission District to choose from, making this an ideal home base for exploring the greater San Francisco area.
If I need to cancel my hotel reservation in Mission District, will I receive a refund?
Yes, the majority of hotel room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a reservation that's non-refundable, you might be able to cancel it and be given a refund within 24 hours of booking. Enter dates in and click on "Search", then you can use the "fully refundable" filter to view the best deals available in Mission District.
What are the top things to see and do in Mission District?
Mission District's sights and attractions like The Chapel, Marsh Theater and Victoria Theatre offer insight into the local culture. SOMA Pilipinas and Southern Exposure are also a couple of places to visit in the neighbourhood. Chase Center and Oracle Park are some popular places to visit in the area around Mission District. While you're out sightseeing in San Francisco, make sure that you visit other sights such as Paxton Gate or Incline Gallery.
How can I get around Mission District and the greater San Francisco area?
For a quick way to explore the city, catch a ride on metro transit at 16th Street Mission Station, 24th Street Mission Station or Right Of Way/20th St Stop.