Mission District Holidays

Book a Hotel + Flight or Car together to unlock savings

Where to stay in Mission District

Find the best Mission District areas and neighborhoods for the activities you enjoy most. Learn more about Mission District
Union Square featuring a skyscraper and a city

Union Square

4/5(287 area reviews)

Known for its charming cafes and popular shops, there's plenty to explore in Union Square. Check out top attractions like Westin St Francis Hotel Glass Elevators and Union Square, and jump on the metro at Powell St & Geary Blvd Stop or Powell St & Post St Stop to see more of the city.

Find hotels in Union Square

Top hotels in Mission District

Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
2500 Mason St San Francisco CA
Fully refundableReserve now, pay when you stay
The price is 3.216.439 ₫ per night from 25 Jan to 26 Jan
3.216.439 ₫
4.867.747 ₫ total
25 Jan - 26 Jan
includes taxes & fees
8.8/10 Excellent! (7,270 reviews)
Clean room great complementary breakfast

Reviewed on 12 Jan 2026

Hotel Riu Plaza Fisherman's Wharf
Hilton San Francisco Financial District

Hilton San Francisco Financial District

4 out of 5
750 Kearny St San Francisco CA
Fully refundableReserve now, pay when you stay
The price is 3.842.190 ₫ per night from 16 Jan to 17 Jan
3.842.190 ₫
4.522.066 ₫ total
16 Jan - 17 Jan
includes taxes & fees
8.6/10 Excellent! (2,276 reviews)
Everything was great. Easy parking, very close to all great restaurants and all walking distance. Staff very helpful and the hotel overall very clean.

Reviewed on 12 Jan 2026

Hilton San Francisco Financial District
Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

3.5 out of 5
1500 Van Ness Ave San Francisco CA
Fully refundableReserve now, pay when you stay
The price is 3.326.589 ₫ per night from 25 Jan to 26 Jan
3.326.589 ₫
3.915.210 ₫ total
25 Jan - 26 Jan
includes taxes & fees
8.8/10 Excellent! (5,127 reviews)
The room was clean, and the staff - from check-in to housekeeping - were all super friendly and helpful.

Reviewed on 12 Jan 2026

Holiday Inn Golden Gateway by IHG
See all 4,957 properties in Mission District
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Mission District holiday package cost?
Our Mission District packages, which begin at just , are an awesome way to save big. Pick your favourite flights, hotels and rental cars to create a customized escape.
How do I get a cheap travel package to Mission District?
By bundling. Flights, rental cars and hotels — combine whatever you need into a Mission District holiday package to save a pile of cash. Score even more deals when you add extras such as sightseeing tours to your booking. But that's not the only impressive part. You have the freedom to customize your holiday your own way. We offer more than 550 partner airlines and 1null000null000 hotels worldwide, so that everyone has a chance to travel and live out those holiday dreams.
Where should I stay in Mission District?
A visit to Mission District isn't complete until you've seen Pier 39 and Alcatraz Island. Book a room close by for quick access to these popular attractions.
What are the top hotels in Mission District?
If it's your first time staying in Mission District, lock in a room at 1906 Mission or Charming And Cosy Dolores Park Condo By Redawning. Both will make you feel at home and are favourites among lots of travellers.
How far in advance should I book my Mission District holiday?
To bag rock-bottom prices, book ASAP. Airlines usually start selling tickets, along with some of the lowest fares, around 12 months ahead of time. Hotels, car rental and experiences should also be booked early so you can have the pick of the bunch. If you've decided on a last-minute getaway in Mission District, there are always lots of great deals to be had on Expedia. Book your escape today!
What does an Expedia Mission District travel package include?
It all boils down to what sort of getaway you want to have. Mission District holiday deals can include car rentals, hotels and flights. You can mix and match to create the travel package that fits your needs. You can also add on activities and experiences after you've booked to pick up even bigger discounts.
What should I know before booking a Mission District travel package?
Booking all the parts of your escape together is one of the best ways to save. Bundle your car rentals, airfares and hotels into a convenient package. But you're not restricted to hotels. Expedia has all types of properties, including holiday rentals like beachfront villas and serviced residences. You've got loads of choices!
Can I choose my airline with a Mission District Expedia holiday package?
With a holiday package, you're always in charge. Whether you want to fly to Mission District in first class or coach, simply select from the available airline options. Expedia has access to more than 550 airline partners around the world.
If I'm not able to travel, can I cancel my Mission District holiday package?
You sure can, and we're here to help. You may be able to cancel or change your Mission District holiday package for free if you booked in the last 24 hours. But you may incur a fee from your airline, hotel or car rental company if you booked more than 24 hours ago. If your travel plans unexpectedly change, visit our Customer Service Portal for more information.

Popular places to visit

Mission Dolores Park

Mission Dolores Park

Mission Dolores Park is just one of the places to see in San Francisco, so why not enjoy the other things to explore during your travels? Discover the beautiful sunsets and top-notch restaurants in this vibrant area.

Mission Dolores Park
Balmy Alley

Balmy Alley

Balmy Alley is just one of the places to see in San Francisco, so why not enjoy the other things to explore during your travels? Experience the acclaimed art galleries and fascinating museums in this vibrant area.

Balmy Alley
Mission San Francisco de Asís

Mission San Francisco de Asís

Learn about the local history of San Francisco when you spend time at Mission San Francisco de Asís. Visit the shops and notable monuments in this vibrant area.

Mission San Francisco de Asís