Search Hotels Near Mission Hospital - Mission Viejo, Mission Viejo

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
21 Dec - 22 Dec
Tomorrow
22 Dec - 23 Dec
Next weekend
26 Dec - 28 Dec
In two weeks
2 Jan - 4 Jan

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Mission Hospital - Mission Viejo hotels

Restaurant
Hampton Inn & Suites Mission Viejo

Hampton Inn & Suites Mission Viejo

Hampton Inn & Suites Mission Viejo
2.5 star property
1.9 km from Mission Hospital - Mission Viejo
9.0 out of 10, Wonderful, (1006)
"good visit - great hot tub"
United States
Robert
The price is 2.783.601 ₫
3.011.717 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Hampton Inn & Suites Mission Viejo
Lobby lounge
Fairfield Inn by Marriott Mission Viejo / Orange County

Fairfield Inn by Marriott Mission Viejo / Orange County

Fairfield Inn by Marriott Mission Viejo / Orange County
2.5 star property
1.9 km from Mission Hospital - Mission Viejo
8.2 out of 10, Very good, (1003)
"The room smelled so good! The staff was friendly"
United States
Marcy
The price is 3.289.375 ₫
3.558.940 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Fairfield Inn by Marriott Mission Viejo / Orange County
Exterior
Laguna Inn & Suites

Laguna Inn & Suites

Laguna Inn & Suites
2.0 star property
2 km from Mission Hospital - Mission Viejo
8.0 out of 10, Very good, (484)
"Staff is always courteous The room and bathroom is always clean. Great place to stay"
United States
Richard M
The price is 2.078.885 ₫
2.245.196 ₫ total
includes taxes & fees
8 Jan - 9 Jan 2026
Laguna Inn & Suites
Banquet hall
Inn at the Mission San Juan Capistrano, Autograph Collection by Marriott

Inn at the Mission San Juan Capistrano, Autograph Collection by Marriott

Inn at the Mission San Juan Capistrano, Autograph Collection by Marriott
4.0 star property
6.8 km from Mission Hospital - Mission Viejo
9.2 out of 10, Wonderful, (358)
"Beautiful property, friendly staff, super close to the town "
United States
osiris
The price is 7.552.405 ₫
9.511.557 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Inn at the Mission San Juan Capistrano, Autograph Collection by Marriott
3 outdoor pools, open 6:00 AM to 10:00 PM, pool cabanas (surcharge)
Renaissance ClubSport Aliso Viejo Laguna Beach Hotel

Renaissance ClubSport Aliso Viejo Laguna Beach Hotel

Renaissance ClubSport Aliso Viejo Laguna Beach Hotel
3.5 star property
6.3 km from Mission Hospital - Mission Viejo
9.0 out of 10, Wonderful, (932)
"Great place to stay"
United States
TODD
The price is 4.947.220 ₫
5.455.100 ₫ total
includes taxes & fees
30 Dec - 31 Dec
Renaissance ClubSport Aliso Viejo Laguna Beach Hotel
Lobby
Ayres Hotel Laguna Woods - Aliso Viejo

Ayres Hotel Laguna Woods - Aliso Viejo

Ayres Hotel Laguna Woods - Aliso Viejo
3.0 star property
7.8 km from Mission Hospital - Mission Viejo
9.4 out of 10, Exceptional, (1719)
"Nice large room, quiet, free parking, Friendly attentive staff"
United States
Emily
The price is 3.526.210 ₫
3.885.706 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Ayres Hotel Laguna Woods - Aliso Viejo
Exterior
Homewood Suites by Hilton Aliso Viejo - Laguna Beach

Homewood Suites by Hilton Aliso Viejo - Laguna Beach

Homewood Suites by Hilton Aliso Viejo - Laguna Beach
3.0 star property
6.1 km from Mission Hospital - Mission Viejo
8.8 out of 10, Excellent, (1003)
"Friendly staff, very nice room, clean and affordable! "
United States
Andrea
The price is 3.431.739 ₫
3.781.605 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Homewood Suites by Hilton Aliso Viejo - Laguna Beach
Garden
Laguna Hills Lodge

Laguna Hills Lodge

Laguna Hills Lodge
2.5 star property
7.1 km from Mission Hospital - Mission Viejo
9.0 out of 10, Wonderful, (2748)
"Beautiful place, clean, friendly, comfortable and convenient location ! "
United States
Nataliya
Laguna Hills Lodge
Exterior
voco Laguna Hills by IHG

voco Laguna Hills by IHG

voco Laguna Hills by IHG
3.0 star property
4 km from Mission Hospital - Mission Viejo
7.8 out of 10, Good, (1004)
"Bar staff (Alex) was very nice and alcohol selection was great!"
United States
Cynthia
The price is 2.315.720 ₫
2.548.871 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
voco Laguna Hills by IHG
3 restaurants, breakfast, lunch, dinner served; Californian cuisine
The Ranch at Laguna Beach

The Ranch at Laguna Beach

The Ranch at Laguna Beach
4.0 star property
9.3 km from Mission Hospital - Mission Viejo
9.4 out of 10, Exceptional, (747)
"Very easy to get through."
United States
Amelia
The price is 11.487.529 ₫
14.768.135 ₫ total
includes taxes & fees
29 Dec - 30 Dec
The Ranch at Laguna Beach
Lobby
Tiller House, Laguna Hills, A Tribute Portfolio Hotel

Tiller House, Laguna Hills, A Tribute Portfolio Hotel

Tiller House, Laguna Hills, A Tribute Portfolio Hotel
4.0 star property
8.9 km from Mission Hospital - Mission Viejo
9.2 out of 10, Wonderful, (32)
"Nicely decorated clean rooms … comfortable beds… Staff is terrific!!!!!"
United States
James
The price is 3.789.360 ₫
4.175.686 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Tiller House, Laguna Hills, A Tribute Portfolio Hotel
Front of property – evening/night
Hilton Garden Inn Irvine Spectrum Lake Forest

Hilton Garden Inn Irvine Spectrum Lake Forest

Hilton Garden Inn Irvine Spectrum Lake Forest
3.5 star property
8.4 km from Mission Hospital - Mission Viejo
9.0 out of 10, Wonderful, (1192)
"Clean room, easy parking, and nice staff"
United States
Herminigilda
The price is 3.107.275 ₫
3.424.062 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Hilton Garden Inn Irvine Spectrum Lake Forest
View from property
TownePlace Suites by Marriott Irvine Lake Forest

TownePlace Suites by Marriott Irvine Lake Forest

TownePlace Suites by Marriott Irvine Lake Forest
3.0 star property
8.4 km from Mission Hospital - Mission Viejo
9.0 out of 10, Wonderful, (239)
"Room was clean for sure. The mattress does need to be replaced as it was uncomfortable to sleep on. "
United States
Maryanne
The price is 3.332.795 ₫
3.672.574 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
TownePlace Suites by Marriott Irvine Lake Forest
Free daily full breakfast
Comfort Inn & Suites Irvine Spectrum

Comfort Inn & Suites Irvine Spectrum

Comfort Inn & Suites Irvine Spectrum
3.5 star property
8.6 km from Mission Hospital - Mission Viejo
9.0 out of 10, Wonderful, (1198)
"Clean quite safe and the best price in town. Loved our stay"
United States
Mary
The price is 2.679.920 ₫
2.947.912 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Comfort Inn & Suites Irvine Spectrum
Lobby lounge
Le Petit Pali Laguna Beach

Le Petit Pali Laguna Beach

Le Petit Pali Laguna Beach
4.0 star property
9.8 km from Mission Hospital - Mission Viejo
9.4 out of 10, Exceptional, (324)
"Warm welcoming staff, beautiful location, close to beaches, shops, and a lovely charming property!"
United States
Rosanna
The price is 5.920.875 ₫
7.963.411 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Le Petit Pali Laguna Beach
Aerial view
Montage Laguna Beach

Montage Laguna Beach

Montage Laguna Beach
5.0 star property
9.9 km from Mission Hospital - Mission Viejo
9.4 out of 10, Exceptional, (687)
"Gorgeous Hotel and location. "
Canada
jacci
The price is 19.999.400 ₫
25.096.142 ₫ total
includes taxes & fees
19 Jan - 20 Jan 2026
Montage Laguna Beach
Bar (on property)
Homewood Suites by Hilton Irvine Spectrum Lake Forest

Homewood Suites by Hilton Irvine Spectrum Lake Forest

Homewood Suites by Hilton Irvine Spectrum Lake Forest
3.0 star property
8.6 km from Mission Hospital - Mission Viejo
9.2 out of 10, Wonderful, (831)
"Spacious rooms, great breakfast, comfortable beds… Enjoyed our stay!"
United States
marcy
The price is 3.780.150 ₫
4.165.536 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Homewood Suites by Hilton Irvine Spectrum Lake Forest
Terrace/patio
SpringHill Suites by Marriott Irvine Lake Forest

SpringHill Suites by Marriott Irvine Lake Forest

SpringHill Suites by Marriott Irvine Lake Forest
3.5 star property
8.9 km from Mission Hospital - Mission Viejo
9.0 out of 10, Wonderful, (555)
"Great place to stay at "
United States
Micheline
The price is 3.220.956 ₫
3.549.333 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
SpringHill Suites by Marriott Irvine Lake Forest
Outdoor pool
Casa Laguna Hotel & Spa

Casa Laguna Hotel & Spa

Casa Laguna Hotel & Spa
4.0 star property
10.1 km from Mission Hospital - Mission Viejo
9.4 out of 10, Exceptional, (937)
"Great small hotel "
United States
David
Casa Laguna Hotel & Spa
Terrace/patio
Hampton Inn by Hilton Irvine Spectrum/Lake Forest

Hampton Inn by Hilton Irvine Spectrum/Lake Forest

Hampton Inn by Hilton Irvine Spectrum/Lake Forest
3.0 star property
8.6 km from Mission Hospital - Mission Viejo
8.8 out of 10, Excellent, (1001)
"The room was excellant and the staff was great. "
United States
Julie
The price is 2.891.492 ₫
3.186.280 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Hampton Inn by Hilton Irvine Spectrum/Lake Forest
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Mission Hospital - Mission Viejo Hotel Reviews

Studio in Quiet Gated SFR Community

Studio in Quiet Gated SFR Community

10/10 Excellent
"The apartment is what I wanted because I prefer privacy. No elevator sounds, no ice buckets being filled late at night!! The room was well stocked with anything a person would need. The host was very polite and accommodating to my needs! Overall, I would certainly recommend the apartment to anyone in need of a place to stay in beautiful Laguna Niguel!!"
Terry 4-night trip
Posted 2 months ago
Studio in Quiet Gated SFR Community

Hotels near other Mission Hospital - Mission Viejo attractions

Burke Williams Day Spa Mission Viejo

You can take time to visit Burke Williams Day Spa Mission Viejo during your travels to Mission Viejo. Wander the beautiful beaches or discover the area's beautiful sunsets.
See properties

Regal Edwards Kaleidoscope

You can take time to visit Regal Edwards Kaleidoscope during your travels to Mission Viejo. Discover the area's beautiful sunsets and cosy cafes.
See properties

Frequently asked questions

What's the area like around Mission Hospital - Mission Viejo?
Mission Hospital - Mission Viejo is located in a welcoming area of Mission Viejo known for its beautiful beaches and cosy cafes. If you're looking for a convenient place to stay, take a look at the 12 hotels and other accommodation options you'll find within a mile.
How many hotels will I find close to Mission Hospital - Mission Viejo?
Expedia has 12 hotels and other accommodation options within a mile from Mission Hospital - Mission Viejo.
If I need to cancel the hotel reservation for my stay near Mission Hospital - Mission Viejo, will I receive a refund?
Yes! Most hotel reservations are fully refundable as long as you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a non-refundable reservation, it might still be possible to cancel it and get a refund within a 24-hour period of your booking. Add dates, click "Search", then you can filter by "fully refundable" to get the best deals near Mission Hospital - Mission Viejo.
What can I see and do near Mission Hospital - Mission Viejo?
You'll want to browse the exhibits at Mission San Juan Capistrano and Orange County Natural History Museum. Enjoy the outdoors at Crown Valley Community Park, Rancho Capistrano Soccer Complex or La Paws Dog Park. Create some family memories at Marguerite Aquatic Complex and Costume Castle.