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Check availability on Mission Valley Business Hotels

Our top choices for Mission Valley business-friendly hotels

Crowne Plaza San Diego - Mission Valley by IHG

Crowne Plaza San Diego - Mission Valley by IHG
3.5 star property
Mission Valley
7.8 out of 10, Good, (1008)
"Breakfast was delicious "
United States
Lukenson
The price is 2.327.042 ₫
2.685.812 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Crowne Plaza San Diego - Mission Valley by IHG

DoubleTree by Hilton Hotel San Diego - Mission Valley

DoubleTree by Hilton Hotel San Diego - Mission Valley
4.0 star property
Mission Valley
8.4 out of 10, Very good, (1411)
"Great hotel in a great area - would definitely stay here again."
United States
Bhupinder
The price is 2.957.238 ₫
3.399.198 ₫ total
includes taxes & fees
3 Jan - 4 Jan 2026
DoubleTree by Hilton Hotel San Diego - Mission Valley

Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa
4.0 star property
Mission Valley
9.2 out of 10, Wonderful, (2956)
"Friendly, staff was very helpful, great size rooms, and over all was an amazing stay"
United States
Naya
The price is 4.005.197 ₫
4.603.773 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Legacy Resort Hotel & Spa

Days Inn by Wyndham San Diego Hotel Circle

Days Inn by Wyndham San Diego Hotel Circle
3.0 star property
Mission Valley
8.0 out of 10, Very good, (2424)
"All was very nice. "
United States
Milton
The price is 2.327.042 ₫
2.674.818 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Days Inn by Wyndham San Diego Hotel Circle

Hilton San Diego Mission Valley

Hilton San Diego Mission Valley
4.0 star property
Mission Valley
8.0 out of 10, Very good, (2250)
"Excelente hotel"
Mexico
Julio
The price is 3.223.637 ₫
3.705.409 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Hilton San Diego Mission Valley

Courtyard by Marriott San Diego Mission Valley/Hotel Circle

Courtyard by Marriott San Diego Mission Valley/Hotel Circle
3.5 star property
Mission Valley
8.4 out of 10, Very good, (1433)
"Good place to stay, and clean"
United States
Yuke
The price is 2.716.637 ₫
3.122.638 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Courtyard by Marriott San Diego Mission Valley/Hotel Circle

Hampton Inn San Diego/Mission Valley

Hampton Inn San Diego/Mission Valley
2.5 star property
Mission Valley
8.8 out of 10, Excellent, (1293)
"Hotel was very clean and the staff was very friendly"
United States
Norma
The price is 2.438.392 ₫
2.802.809 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Hampton Inn San Diego/Mission Valley

Best Western Seven Seas

Best Western Seven Seas
3.0 star property
Mission Valley
7.8 out of 10, Good, (3044)
"Nice room, good ambiance, central location "
United States
ANDREW
The price is 1.950.872 ₫
2.242.429 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Best Western Seven Seas

Handlery Hotel

Handlery Hotel
3.5 star property
Mission Valley
8.2 out of 10, Very good, (2234)
"Staff was amazing and very accommodating. Always recommended staying here. "
United States
Taja
Handlery Hotel

Homewood Suites by Hilton San Diego Hotel Circle/SeaWorld Area

Homewood Suites by Hilton San Diego Hotel Circle/SeaWorld Area
3.0 star property
Mission Valley
8.8 out of 10, Excellent, (1303)
"Clean hotel and great staff. "
United States
Ajay
The price is 3.000.410 ₫
3.448.821 ₫ total
includes taxes & fees
6 Jan - 7 Jan 2026
Homewood Suites by Hilton San Diego Hotel Circle/SeaWorld Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Mission Valley Hotel Reviews

Frequently asked questions

Why book your business-friendly hotel in Mission Valley with Expedia?
We're here to help you find a fabulous business-friendly hotel when work takes you on the road. From room service and free WiFi to gyms and spas, our stays come with the conveniences you'll need to settle that big contract.
How can I find cheap business-friendly hotels in Mission Valley?
Select the "business friendly" filter, listed under the "traveller experience" heading, to find cheap business-friendly hotels in Mission Valley. Then fine-tune your search by your per-night budget. Looking for stays away from the centre is another good way to save.