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15 Dec - 16 Dec
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16 Dec - 17 Dec
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19 Dec - 21 Dec
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26 Dec - 28 Dec

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Our top choices for National Medical Center (Siglo XXI) hotels

Penthouse with a Private Terrace | Private kitchen
ULIV Roma Norte

ULIV Roma Norte

ULIV Roma Norte
4.0 star property
Roma Norte, 0.8 km from National Medical Center (Siglo XXI)
9.6 out of 10, Exceptional, (293)
"Clean rooms, very friendly and helpful staff, felt very safe! "
Canada
EMMA
ULIV Roma Norte
Premium Double Room | Minibar, in-room safe, laptop workspace, blackout curtains
ONTO Alvaro Obregon Mexico City

ONTO Alvaro Obregon Mexico City

ONTO Alvaro Obregon Mexico City
4.0 star property
Roma Norte, 1.2 km from National Medical Center (Siglo XXI)
9.6 out of 10, Exceptional, (79)
"Very nice hotel and service from the staff. "
United States
ANTONIO
ONTO Alvaro Obregon Mexico City
Front of property
Casa Malí by Dominion

Casa Malí by Dominion

Casa Malí by Dominion
4.0 star property
Hipódromo, 1.8 km from National Medical Center (Siglo XXI)
9.6 out of 10, Exceptional, (337)
"Nice and safe location: Convenient to coffee shops, restaurants, and parks. Nice hotel . Highly recommended!"
United States
Huyen Anh
Casa Malí by Dominion
Fridge, microwave, oven, coffee/tea maker
OM686 Urban Lofts Short-Long Stays

OM686 Urban Lofts Short-Long Stays

OM686 Urban Lofts Short-Long Stays
3.0 star property
0.9 km from National Medical Center (Siglo XXI)
9.4 out of 10, Exceptional, (247)
"A joyful experience "
United States
Daimon
The price is 2.220.005 ₫
2.686.206 ₫ total
includes taxes & fees
12 Jan - 13 Jan 2026
OM686 Urban Lofts Short-Long Stays
Interior
Cuadra 134 Residencial Condesa

Cuadra 134 Residencial Condesa

Cuadra 134 Residencial Condesa
4.5 star property
Roma Norte, 1 km from National Medical Center (Siglo XXI)
9.4 out of 10, Exceptional, (230)
"very nice accommodation / a little noisy / but overall a pleasant experience "
Canada
hanif
The price is 2.962.606 ₫
3.540.314 ₫ total
includes taxes & fees
13 Jan - 14 Jan 2026
Cuadra 134 Residencial Condesa
Suite (Master) | In-room safe, soundproofing, free WiFi, bed sheets
Casa Goliana La Roma

Casa Goliana La Roma

Casa Goliana La Roma
4.0 star property
Roma Norte, 1.4 km from National Medical Center (Siglo XXI)
9.4 out of 10, Exceptional, (90)
"Such nice hosts, beautiful property, delicious breakfast "
United States
Rina
Casa Goliana La Roma
Reception
ULIV Pulse Roma - Condesa

ULIV Pulse Roma - Condesa

ULIV Pulse Roma - Condesa
4.5 star property
Roma Sur, 1.6 km from National Medical Center (Siglo XXI)
9.4 out of 10, Exceptional, (399)
"Nice location, easy check in , i enjoyed my stay "
United States
ifeka
The price is 2.770.137 ₫
3.310.314 ₫ total
includes taxes & fees
17 Dec - 18 Dec
ULIV Pulse Roma - Condesa
Panoramic Apartment | Terrace/patio
Casa Oliva

Casa Oliva

Casa Oliva
3.0 star property
Roma Norte, 1.7 km from National Medical Center (Siglo XXI)
9.4 out of 10, Exceptional, (74)
"Great accommodations in a cool neighbourhood "
Canada
Matt
The price is 5.229.955 ₫
6.249.802 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Casa Oliva
Terrace/patio
Casa Miravalle

Casa Miravalle

Casa Miravalle
4.0 star property
Hipódromo, 1.8 km from National Medical Center (Siglo XXI)
9.4 out of 10, Exceptional, (168)
"Great staff, clean room, easy access in and out of the building. "
United States
Desirae
Casa Miravalle
Comfort Apartment, City View | Terrace/patio
Caliza Roma Residences by Tasman

Caliza Roma Residences by Tasman

Caliza Roma Residences by Tasman
2.5 star property
Roma Norte, 1.8 km from National Medical Center (Siglo XXI)
9.4 out of 10, Exceptional, (64)
"It was a great stay, and very walkable to a lot of eating, shopping, and drinking. Loved the area. "
United States
Cristina
Caliza Roma Residences by Tasman
Hallway
Hotel Escala Colonia Roma

Hotel Escala Colonia Roma

Hotel Escala Colonia Roma
2.0 star property
Roma Norte, 0.6 km from National Medical Center (Siglo XXI)
9.2 out of 10, Wonderful, (360)
"Clean room, nice , helpfull staff , geografical situation amazing"
United Kingdom
El abed
The price is 1.372.318 ₫
1.639.920 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Hotel Escala Colonia Roma
Terrace Suite | Egyptian cotton sheets, premium bedding, Select Comfort beds, minibar
HOTEL LUCA

HOTEL LUCA

HOTEL LUCA
4.0 star property
Roma Norte, 1.1 km from National Medical Center (Siglo XXI)
9.2 out of 10, Wonderful, (315)
"Great location, spotless large room; outstanding cleaning staff, great breakfast on roof patio with fantastic staff. "
United States
Allison
HOTEL LUCA
Junior Double Room, 2 Double Beds, Terrace | Minibar, in-room safe, laptop workspace, blackout curtains
Colony Residences & Suites

Colony Residences & Suites

Colony Residences & Suites
2.5 star property
Roma Norte, 1.6 km from National Medical Center (Siglo XXI)
9.2 out of 10, Wonderful, (124)
"The hotel was nice"
United States
Angelica
The price is 2.563.238 ₫
3.063.077 ₫ total
includes taxes & fees
16 Dec - 17 Dec
Colony Residences & Suites
Superior Apartment, Balcony | Living area | Flat-screen TV
MEDELLIN 148 by Mr. W

MEDELLIN 148 by Mr. W

MEDELLIN 148 by Mr. W
3.0 star property
Roma Norte, 1.4 km from National Medical Center (Siglo XXI)
9.2 out of 10, Wonderful, (79)
"Would surely stay again. "
United States
Justin
The price is 2.909.932 ₫
3.521.018 ₫ total
includes taxes & fees
17 Dec - 18 Dec
MEDELLIN 148 by Mr. W
Front of property
Brick Hotel - Small Luxury Hotels of the World

Brick Hotel - Small Luxury Hotels of the World

Brick Hotel - Small Luxury Hotels of the World
4.5 star property
Roma Norte, 1.4 km from National Medical Center (Siglo XXI)
9.2 out of 10, Wonderful, (170)
"Excellent stay with a great staff and beautiful hotel"
United States
Gregory
Brick Hotel - Small Luxury Hotels of the World
Terrace/patio
ULIV Cibeles

ULIV Cibeles

ULIV Cibeles
4.5 star property
Roma Norte, 1.9 km from National Medical Center (Siglo XXI)
9.2 out of 10, Wonderful, (866)
"Friendly staff, great location and restaurants "
United States
Tobi
ULIV Cibeles
Superior Studio, Park View | Terrace/patio
Nido Parque Mexico

Nido Parque Mexico

Nido Parque Mexico
4.0 star property
Hipódromo, 1.8 km from National Medical Center (Siglo XXI)
9.2 out of 10, Wonderful, (82)
"Clean, comfortable, courteous staff."
United States
Randy
The price is 2.179.782 ₫
2.637.536 ₫ total
includes taxes & fees
17 Dec - 18 Dec
Nido Parque Mexico
Suite (Suite A) | Living room | Flat-screen TV
Casa Corp

Casa Corp

Casa Corp
3.5 star property
Hipódromo, 2 km from National Medical Center (Siglo XXI)
9.2 out of 10, Wonderful, (66)
"It was beautiful "
United States
SELENA
Casa Corp
City Studio, Balcony | View from room
Casa Cibeles by Lumina

Casa Cibeles by Lumina

Casa Cibeles by Lumina
4.0 star property
Roma Norte, 1.9 km from National Medical Center (Siglo XXI)
9.2 out of 10, Wonderful, (94)
"We had a wonderful stay! The room was spotless, beautifully maintained, and very comfortable. The amenities were great and made our visit even more enjoyable. What truly stood out, though, was the staff — they were warm, welcoming, and went out of their way to make us feel at home. Overall, a fantastic experience and I would definitely stay here again!"
United States
Nayeli
The price is 4.214.239 ₫
5.036.015 ₫ total
includes taxes & fees
22 Dec - 23 Dec
Casa Cibeles by Lumina
Front of property
Hotel Casa Izel Roma Norte

Hotel Casa Izel Roma Norte

Hotel Casa Izel Roma Norte
3.5 star property
Roma Norte, 1.8 km from National Medical Center (Siglo XXI)
9.2 out of 10, Wonderful, (87)
"Friendly staff, clean room, it is in the center of the city everything from shops, restaurants and attractions were within walking distance."
United States
Lillian
The price is 9.000.041 ₫
10.755.049 ₫ total
includes taxes & fees
16 Dec - 17 Dec
Hotel Casa Izel Roma Norte
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top National Medical Center Hotel Reviews

ULIV Mexico City

ULIV Mexico City

10/10 Excellent
"This was a great place to stay in Roma Norte area. Easy walk to great restaurants, parks, etc. Would definitely recommend. The only issue staying in this area is the noise. It is close to two main intersections where there’s quite a bit of traffic all day and most of the night. We were sincerely grateful to the front desk staff. They were very kind and attentive."
Cole 4-night trip
Posted 1 day ago
ULIV Mexico City

Hotels near other National Medical Center attractions

Abelardo L. Rodriguez Murals

Enjoy an outing to Abelardo L. Rodriguez Murals during your stay in Mexico City. Experience the fascinating museums and great live music in this vibrant area.
See properties

Parque Delta

During your visit to Mexico City, you can browse for the perfect souvenirs at Parque Delta. Experience the fascinating museums and acclaimed art galleries in this vibrant area.
See properties

Frequently asked questions

What's the area like around National Medical Center (Siglo XXI)?
National Medical Center (Siglo XXI) is located in a historic area of Mexico City known for its top museums and popular art scene. If you're looking for a convenient place to stay, take a look at the 650 hotels and other accommodation options you'll find within a mile.
How many hotels will I be able to find close to National Medical Center (Siglo XXI)?
Expedia has 650 hotels and other accommodation options within a mile from National Medical Center (Siglo XXI).
If I need to cancel the hotel reservation for my stay near National Medical Center (Siglo XXI), will I receive a refund?
Yes, most room reservations are refundable provided that you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a non-refundable reservation, you might be able to cancel it and be given a refund within a 24-hour period of your booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to view the best deals near National Medical Center (Siglo XXI).
What can I see and do near National Medical Center (Siglo XXI)?
Chapultepec Castle, Templo Mayor Museum and Frida Kahlo Museum feature a variety of fascinating exhibits to see while you're in town. Paseo de la Reforma, Cibeles Fountain and Diana the Huntress Fountain are some of the local landmarks to explore. You can watch performances at Blackberry Auditorium, Teatro Metropólitan and Insurgentes Theater if you're interested in local theatre.
How can I get to National Medical Center (Siglo XXI)?
With so many choices for transport, seeing the area around National Medical Center (Siglo XXI) is a breeze. You can access metro transport at Revolution Station, Metrobús Revolución Station and Buenavista Metro Station. To see more of the larger area, ride aboard one of the trains from Mexico City Buenavista Station.

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