Search Hotels in Oyster Reef, Hilton Head Island

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
9 Dec - 10 Dec
Tomorrow
10 Dec - 11 Dec
This weekend
12 Dec - 14 Dec
Next weekend
19 Dec - 21 Dec

Filter by

Guest rating
Guest rating
Star rating

Top Trending Hotels Near Oyster Reef, Hilton Head Island

Exterior
Best Western Sea Island Inn

Best Western Sea Island Inn

2.5 star property
21.4 km from Oyster Reef
9.4 out of 10, Exceptional, (1003)
"Perfect spot!"
United States
Tricia
The price is 3.677.375 ₫
4.045.113 ₫ total
includes taxes & fees
16 Dec - 17 Dec
Best Western Sea Island Inn
Miscellaneous
Super 8 by Wyndham Port Royal/Beaufort

Super 8 by Wyndham Port Royal/Beaufort

2.0 star property
17.6 km from Oyster Reef
6.0 out of 10, (905)
"The room could have been a little cleaner but all and all it was Great! "
United States
Gina
The price is 1.613.354 ₫
1.774.690 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Super 8 by Wyndham Port Royal/Beaufort
Premium bedding, individually decorated, individually furnished
Beaufort Inn

Beaufort Inn

3.5 star property
21.4 km from Oyster Reef
9.0 out of 10, Wonderful, (1003)
"If you are looking for a unique place to stay, this would be it. Staff was great and the rooms were clean."
United States
Samantha
Beaufort Inn
Lobby
Hampton Inn Hilton Head

Hampton Inn Hilton Head

2.5 star property
Mid Island, 3.2 km from Oyster Reef
8.4 out of 10, Very good, (1004)
"Nice staff, clean room, tasty food "
United States
William
The price is 2.404.214 ₫
2.644.634 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Hampton Inn Hilton Head
Snack bar
Tru by Hilton Beaufort, SC

Tru by Hilton Beaufort, SC

2.5 star property
22.2 km from Oyster Reef
9.0 out of 10, Wonderful, (704)
"Awesome stay!!!"
United States
Michael
The price is 2.509.662 ₫
2.760.629 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Tru by Hilton Beaufort, SC
Exterior
Hilton Garden Inn Beaufort

Hilton Garden Inn Beaufort

3.0 star property
22.3 km from Oyster Reef
8.4 out of 10, Very good, (1003)
"Good hotel"
United States
joshua
The price is 2.354.743 ₫
2.590.217 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Hilton Garden Inn Beaufort
Exterior
Rhett House Inn

Rhett House Inn

4.0 star property
21.5 km from Oyster Reef
9.2 out of 10, Wonderful, (641)
"Quaint. Dining room and breakfast excellent"
United States
Deborah
The price is 3.840.921 ₫
5.069.916 ₫ total
includes taxes & fees
3 Jan - 4 Jan 2026
Rhett House Inn
Exterior
607 Bay Inn Downtown Beaufort

607 Bay Inn Downtown Beaufort

2.5 star property
21.4 km from Oyster Reef
9.8 out of 10, Exceptional, (89)
"Great Inn! Location, view, cleanliness, friendly staff!"
United States
Nicole
607 Bay Inn Downtown Beaufort
Reception
Hampton Inn Beaufort

Hampton Inn Beaufort

2.5 star property
22 km from Oyster Reef
8.4 out of 10, Very good, (1001)
"Friendly staff, modern renovation inside, the room was very comfortable and the coffee selection was fantastic."
United States
Jackie
The price is 2.509.758 ₫
2.760.734 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Hampton Inn Beaufort
Terrace/patio
Holiday Inn Hotel & Suites Beaufort at Highway 21 by IHG

Holiday Inn Hotel & Suites Beaufort at Highway 21 by IHG

3.0 star property
22.4 km from Oyster Reef
8.2 out of 10, Very good, (1002)
"great location "
United States
Huntley
The price is 2.346.218 ₫
2.580.839 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Holiday Inn Hotel & Suites Beaufort at Highway 21 by IHG
Free daily on-the-go breakfast
Howard Johnson by Wyndham Beaufort/Parris Island

Howard Johnson by Wyndham Beaufort/Parris Island

2.0 star property
22.3 km from Oyster Reef
6.0 out of 10, (891)
"Room was good "
United States
INDIRA
The price is 2.078.644 ₫
2.286.508 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Howard Johnson by Wyndham Beaufort/Parris Island
Lobby lounge
Comfort Suites near MCAS Beaufort

Comfort Suites near MCAS Beaufort

2.5 star property
21.3 km from Oyster Reef
7.4 out of 10, Good, (1004)
"I felt safe and the room was very clean. I received great customer service "
United States
Tonya
The price is 2.218.362 ₫
2.585.189 ₫ total
includes taxes & fees
28 Dec - 29 Dec
Comfort Suites near MCAS Beaufort
View from property
City Loft Hotel

City Loft Hotel

3.5 star property
21.5 km from Oyster Reef
9.4 out of 10, Exceptional, (758)
"Great place to stay in city center Beaufort. Easy free parking, friendly staff, comfy mattresses, nice bathroom and shower. Location was perfect for walking to shops and restaurants."
United States
Laura
The price is 3.762.912 ₫
4.139.098 ₫ total
includes taxes & fees
23 Dec - 24 Dec
City Loft Hotel
View from property
Cuthbert House

Cuthbert House

4.5 star property
21.5 km from Oyster Reef
9.2 out of 10, Wonderful, (951)
"Excellent accommodations. Staff was very friendly & helpful. Will definitely come back. The Inn is beautiful. "
United States
Melanie
The price is 9.929.247 ₫
10.922.171 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Cuthbert House
Exterior
Hilton Garden Inn Hilton Head

Hilton Garden Inn Hilton Head

3.0 star property
8.4 km from Oyster Reef
8.6 out of 10, Excellent, (1007)
"Wonderful stay!"
United States
Ashley
The price is 2.415.550 ₫
2.657.104 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Hilton Garden Inn Hilton Head
Balcony
Anchorage 1770

Anchorage 1770

5.0 star property
21.4 km from Oyster Reef
9.2 out of 10, Wonderful, (218)
"Great property at a wonderful location."
United States
Dave
Anchorage 1770
View from room
Marriott's Harbour Club

Marriott's Harbour Club

3.5 star property
Harbour Town, 14.5 km from Oyster Reef
9.2 out of 10, Wonderful, (61)
"The staff was extremely inviting, professional, and kind. Parking was extremely easy we stayed in villa 3939. It was very large, clean, and had a great view. The property was conveniently located within the area and very walkable. It is very dark at night but we felt safe walking back from dinner. I’d definitely recommend this property for a quiet and peaceful getaway."
United States
ANGELEE
The price is 4.297.006 ₫
4.726.706 ₫ total
includes taxes & fees
3 Jan - 4 Jan 2026
Marriott's Harbour Club
Exterior
Sleep Inn Beaufort near MCAS

Sleep Inn Beaufort near MCAS

2.5 star property
22.1 km from Oyster Reef
7.4 out of 10, Good, (1004)
"Overall i would stay here again."
United States
Joshua
The price is 2.147.712 ₫
2.362.484 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Sleep Inn Beaufort near MCAS
Outdoor pool
Home2 Suites BY Hilton Beaufort, SC

Home2 Suites BY Hilton Beaufort, SC

3.0 star property
22.3 km from Oyster Reef
9.2 out of 10, Wonderful, (719)
"Room was spotless and beds comfortable"
United States
Judy
The price is 2.720.558 ₫
2.992.614 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Home2 Suites BY Hilton Beaufort, SC
Basic Room, Multiple Beds, Non Smoking | Free WiFi, bed sheets
Simple Rewards Inn

Simple Rewards Inn

2.5 star property
Mid Island, 3.4 km from Oyster Reef
8.8 out of 10, Excellent, (1001)
"Great coffee and breakfast"
United States
Richard
The price is 2.398.942 ₫
2.638.836 ₫ total
includes taxes & fees
13 Dec - 14 Dec
Simple Rewards Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Oyster Reef

Find the best Oyster Reef areas for the activities you enjoy most.

Sea Pines

While visiting Sea Pines, you might make a stop by sights like Atlantic Dunes by Davis Love III and Harbour Town Golf Links.

Mid Island

While visiting Mid Island, you might make a stop by sights like Adventure Cove and Shelter Cove Harbour.

Hilton Head featuring heritage architecture
Photo by Hilton Head Island Visitor & Convention Bureau
Open Photo by Hilton Head Island Visitor & Convention Bureau

South End

If you're spending some time in South End, Sea Pines Forest Preserve and Heron Point by Pete Dye at Sea Pines Resort are top sights worth seeing.

North Forest Beach

If you're spending some time in North Forest Beach, Coligny Plaza and Coligny Beach are top sights worth seeing.

South Forest Beach

If you're spending some time in South Forest Beach, Sea Pines Forest Preserve and Coligny Beach are top sights worth seeing.

Top Oyster Reef Hotel Reviews

Explore a world of travel with Expedia

Frequently asked questions

What's it like in Oyster Reef?
Travellers will be sure to find plenty to entertain them in Hilton Head Island's Oyster Reef neighbourhood. Are you looking for Oyster Reef travel tips? Make sure that you visit Oyster Bay Golf Club and Oyster Reef Golf Club while you're in the neighbourhood.
If I need to cancel my hotel reservation in Oyster Reef, will I receive a refund?
Yes, you'll find most hotel bookings are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you have a reservation that's non-refundable, it may still be possible to cancel it and get a refund within a 24-hour period of your booking. Add your dates and click on "Search", then filter by "fully refundable" to get top deals in Oyster Reef.
What is there to do around this Hilton Head Island neighbourhood?
If you're looking for activities to do while you're in Oyster Reef, look into Oyster Bay Golf Club and Oyster Reef Golf Club. When you're sightseeing in Hilton Head Island, Palmetto Hall Golf and Country Club and Fort Howell are also worth a stop.