
Panama City Holidays
Book a Hotel + Flight or Car together to unlock savings
Where to stay in Panama City
Find the best Panama City areas and neighborhoods for the activities you enjoy most. Learn more about Panama City

Casco Viejo
3.5/5(3 area reviews)
Unique features of Casco Viejo include the historical sites and bars. Make a stop by Metropolitan Cathedral of Panama or Interoceanic Canal Museum while you're exploring the area.
Top hotels in Panama City

Hotel Riu Plaza Panama
Calle 50, Urb. Marbella, Panama City, Panama
Fully refundableReserve now, pay when you stay
The price is 2.870.143 ₫ per night from 25 Aug to 26 Aug
2.870.143 ₫
3.157.157 ₫ total
25 Aug - 26 Aug
includes taxes & fees
9/10 Wonderful! (4,167 reviews)
"Staff was great!"
Reviewed on 16 Aug 2025

Waymore Hotel Spa & Casino
Calle Augusto Samuel Boyd y Calle Eusebi, Panama City
Fully refundableReserve now, pay when you stay
The price is 2.129.389 ₫ per night from 21 Aug to 22 Aug
2.129.389 ₫
2.342.328 ₫ total
21 Aug - 22 Aug
includes taxes & fees
9/10 Wonderful! (417 reviews)
"The Waymore is totally updated (stayed in a remodelled room. This used to be the Veneto hotel) and they did a good job. My room was large, comfortable, with all modern ammenities like rainshowers, expresso machine, smart tv. The pool and gym are large and breakfast was a good buffett. It is only ..."
Reviewed on 18 Aug 2025

Sheraton Grand Panama
Via Israel And 77th Street, Panama City, Panama
Fully refundableReserve now, pay when you stay
The price is 3.525.757 ₫ per night from 26 Aug to 27 Aug
3.525.757 ₫
3.878.332 ₫ total
26 Aug - 27 Aug
includes taxes & fees
8.4/10 Very Good! (929 reviews)
"Excellent and friendly customer service"
Reviewed on 16 Aug 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Popular places to visit

Multiplaza Pacific Mall
During your trip to Panama City, you can search for that perfect souvenir at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.

Cinta Costera
Explore the great outdoors at Cinta Costera, a lovely green space in Panama City. While you're in the area, stroll along the seaside.

Avenida Balboa
You can browse for the perfect souvenirs at Avenida Balboa during your stay in Panama City. While you're in the area, wander around the natural setting.