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Our top choices for Piazza Santo Spirito hotels

SPIRIT OF FLORENCE Boutique Rooms

SPIRIT OF FLORENCE Boutique Rooms
San Frediano, < 0.1 km from Piazza Santo Spirito
10.0 out of 10, Exceptional, (24)
"This boutique was an absolute must stay. From the location to the comfort of our room and the lovely staff, it was all you could ask for during a stay in Florence. The walkability was incredible, and even though there is a lively crowd nightly outside of the building, your room is peaceful. Highly recommend this hotel to anyone looking for a unique stay in Florence! "
United States
Chris
The price is 4.668.256 ₫
5.505.178 ₫ total
includes taxes & fees
17 Dec - 18 Dec
SPIRIT OF FLORENCE Boutique Rooms

Oltrarno Splendid

Oltrarno Splendid
San Frediano, 0.2 km from Piazza Santo Spirito
10.0 out of 10, Exceptional, (97)
"It was Wonderful!!!"
United States
MARGARITA
The price is 4.482.787 ₫
5.362.845 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Oltrarno Splendid

Soprarno Suites

Soprarno Suites
Historic Centre of Florence, 0.1 km from Piazza Santo Spirito
9.8 out of 10, Exceptional, (393)
"Beautiful rooms in ideal location and staff was friendly and helpful"
Canada
Dara
The price is 5.021.529 ₫
5.955.461 ₫ total
includes taxes & fees
17 Dec - 18 Dec
Soprarno Suites

AdAstra Suites

AdAstra Suites
San Frediano, 0.2 km from Piazza Santo Spirito
9.8 out of 10, Exceptional, (221)
"Great Room - Lovely breakfast excellent strong Cappuccino and lovely yoghurts. Thanks see you soon. "
United Kingdom
Tim
The price is 5.273.867 ₫
6.233.033 ₫ total
includes taxes & fees
16 Dec - 17 Dec
AdAstra Suites

Toscanelli Residenza D'epoca

Toscanelli Residenza D'epoca
Historic Centre of Florence, 0.2 km from Piazza Santo Spirito
9.6 out of 10, Exceptional, (366)
"Great location with lots of sights and restaurants in walklng distance. "
Ireland
jennifer
The price is 2.271.043 ₫
2.929.927 ₫ total
includes taxes & fees
19 Dec - 20 Dec
Toscanelli Residenza D'epoca

Stella d'Italia

Stella d'Italia
4.0 star property
Duomo, 0.6 km from Piazza Santo Spirito
10.0 out of 10, Exceptional, (162)
"Great location, friendly staff. "
United Kingdom
Ariadne
The price is 4.697.274 ₫
5.598.780 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Stella d'Italia

Pitti Suite 13 residenza d'epoca

Pitti Suite 13 residenza d'epoca
Historic Centre of Florence, 0.2 km from Piazza Santo Spirito
9.8 out of 10, Exceptional, (6)
"Good location and great communication. Responded almost immediately and was very accommodating. "
United States
William
The price is 4.742.280 ₫
5.587.470 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Pitti Suite 13 residenza d'epoca

Palazzo Martellini Residenza d'Epoca

Palazzo Martellini Residenza d'Epoca
Historic Centre of Florence, 0.2 km from Piazza Santo Spirito
9.6 out of 10, Exceptional, (70)
"The whole experience was very pleasurable."
Canada
Dejan
Palazzo Martellini Residenza d'Epoca

Numa Florence Palazzo Belfiore

Numa Florence Palazzo Belfiore
Historic Centre of Florence, 0.2 km from Piazza Santo Spirito
9.6 out of 10, Exceptional, (371)
"Great property, plenty of space for my family. The location is great, we were able to walk everywhere including the train station. "
United States
Loren
The price is 2.975.254 ₫
3.642.876 ₫ total
includes taxes & fees
18 Dec - 19 Dec
Numa Florence Palazzo Belfiore

B & Beatrice

B & Beatrice
Historic Centre of Florence, 0.1 km from Piazza Santo Spirito
9.4 out of 10, Exceptional, (110)
"Good location Helpful staff"
United States
maryjo
The price is 2.697.818 ₫
3.338.562 ₫ total
includes taxes & fees
14 Dec - 15 Dec
B & Beatrice

Hotel Milu Florence

Hotel Milu Florence
4.0 star property
San Giovanni, 0.6 km from Piazza Santo Spirito
9.8 out of 10, Exceptional, (602)
"Great central walkable location. Boutique hotel with wonderfully friendly and professional staff, who are very responsive by WhatsApp for concierge questions or requests. Rooms are clean and normal sized for European hotels. Wooden floors (not carpeted) has a breakfast option on the top floor but also plenty of cafes nearby. "
United States
Kristin
The price is 4.012.177 ₫
5.307.794 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Hotel Milu Florence

Portrait Firenze - Lungarno Collection

Portrait Firenze - Lungarno Collection
5.0 star property
San Giovanni, 0.5 km from Piazza Santo Spirito
9.8 out of 10, Exceptional, (301)
"Great location and got fantastic service from the hotel. Room was very clean and comfortable. Definitely my first choice for staying in Firenze!"
Canada
LEI
The price is 23.662.854 ₫
26.523.754 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Portrait Firenze - Lungarno Collection

Ponte Vecchio Suites & Spa

Ponte Vecchio Suites & Spa
4.0 star property
Historic Centre of Florence, 0.4 km from Piazza Santo Spirito
9.6 out of 10, Exceptional, (1001)
"The entire staff was so warm and welcoming. The morning breakfasts were a great way to start each day. I would highly recommend anyone looking for a hotel to give this great place a try. "
United States
Michael
The price is 5.576.673 ₫
6.566.119 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Ponte Vecchio Suites & Spa

Hotel Horto Convento

Hotel Horto Convento
4.0 star property
San Frediano, 0.7 km from Piazza Santo Spirito
9.8 out of 10, Exceptional, (598)
"Excellent stay"
United States
Renata
The price is 3.132.358 ₫
3.877.373 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Hotel Horto Convento

Hotel Lungarno - Lungarno Collection

Hotel Lungarno - Lungarno Collection
5.0 star property
Historic Centre of Florence, 0.4 km from Piazza Santo Spirito
9.6 out of 10, Exceptional, (599)
"Excellent location! Truly a 5 star hotel ! Great service, breakfast, and service . Bedrooms were clean! Bathrooms were excellent!"
Canada
Pam
The price is 15.420.665 ₫
17.456.193 ₫ total
includes taxes & fees
13 Dec - 14 Dec
Hotel Lungarno - Lungarno Collection

Davanzati

Davanzati
3.0 star property
San Giovanni, 0.6 km from Piazza Santo Spirito
9.6 out of 10, Exceptional, (886)
"Great location "
Canada
Brent
The price is 3.199.544 ₫
3.890.461 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Davanzati

Leone Blu Suites | UNA Esperienze

Leone Blu Suites | UNA Esperienze
Duomo, 0.5 km from Piazza Santo Spirito
9.6 out of 10, Exceptional, (195)
"We had a wonderful stay. Service was impeccable. Wonderful breakfast is recommended. Great location, comfortable bed and plenty of hot water pressure."
United States
Peter
The price is 6.476.679 ₫
7.556.126 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Leone Blu Suites | UNA Esperienze

QK Costa58 Home Tower

QK Costa58 Home Tower
San Niccolò, 0.6 km from Piazza Santo Spirito
9.6 out of 10, Exceptional, (177)
"The building and room were very well maintained and clean. Nice quiet place to rest. Close to everything and we walked easily everywhere. Great place and location. Would stay there again. "
Canada
Nathan
The price is 2.816.094 ₫
4.393.040 ₫ total
includes taxes & fees
14 Dec - 15 Dec
QK Costa58 Home Tower

IL Tornabuoni The Unbound Collection by Hyatt

IL Tornabuoni The Unbound Collection by Hyatt
5.0 star property
Duomo, 0.6 km from Piazza Santo Spirito
9.6 out of 10, Exceptional, (107)
"Great location and very helpful and friendly staff. "
United States
Sheru
The price is 11.304.749 ₫
12.928.685 ₫ total
includes taxes & fees
15 Dec - 16 Dec
IL Tornabuoni The Unbound Collection by Hyatt

Piazza Pitti Palace

Piazza Pitti Palace
Historic Centre of Florence, 0.4 km from Piazza Santo Spirito
9.2 out of 10, Wonderful, (120)
"Loved the hotel and friendly staff "
United States
Wojciech
Piazza Pitti Palace
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Piazza Santo Spirito Hotel Reviews

Hotels near other Piazza Santo Spirito attractions

Frequently asked questions

What's the area like around Piazza Santo Spirito?
Piazza Santo Spirito is located in a historic area of Florence known for its stunning cathedral and popular art scene. If you're looking for a convenient place to stay, take a look at the 3050 hotels and other accommodation options you'll find within a mile.
How many hotels will I find close to Piazza Santo Spirito?
Expedia has 3050 hotels and other accommodation options within a mile from Piazza Santo Spirito.
If I need to cancel the hotel reservation for my stay near Piazza Santo Spirito, will I receive a refund?
Yes! You'll find that most hotel reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you have a non-refundable reservation, you might be able to still cancel and receive a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then filter by "fully refundable" to get the best deals near Piazza Santo Spirito.
What can I see and do near Piazza Santo Spirito?
Study the collections at Uffizi Gallery, Galileo Museum - Institute and Museum of the History of Science or Basilica of Santa Maria Novella. Pitti Palace, Via de' Tornabuoni and Ponte Vecchio are landmarks that you won't want to miss. You can check out the local talent at Teatro Verdi, Visarno Arena and Teatro Comunale Florence.
How can I get to Piazza Santo Spirito?
With so many ways to get around, seeing all of the area near Piazza Santo Spirito is easy. Nearby metro stations include Unità Tram Stop, Valfonda - Stazione Santa Maria Novella Tram Stop and San Marco University Tram Stop. If you're taking a train into town, Florence (ZMS-Santa Maria Novella Train Station) and Florence Santa Maria Novella Station are the closest stops to Historic Centre of Florence.

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