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Check prices for these dates

Tonight
16 Dec - 17 Dec
Tomorrow
17 Dec - 18 Dec
This weekend
19 Dec - 21 Dec
Next weekend
26 Dec - 28 Dec

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Our top choices for Piazza Santo Spirito hotels

Royal Double Room | Minibar, in-room safe, soundproofing, free WiFi
Oltrarno Splendid

Oltrarno Splendid

Oltrarno Splendid
San Frediano, 0.2 km from Piazza Santo Spirito
10.0 out of 10, Exceptional, (97)
"It was Wonderful!!!"
United States
MARGARITA
The price is 4.274.206 ₫
5.134.003 ₫ total
includes taxes & fees
8 Jan - 9 Jan 2026
Oltrarno Splendid
Free daily buffet breakfast
Stella d'Italia

Stella d'Italia

Stella d'Italia
4.0 star property
Duomo, 0.6 km from Piazza Santo Spirito
10.0 out of 10, Exceptional, (162)
"Great location, friendly staff. "
United Kingdom
Ariadne
The price is 4.703.775 ₫
5.606.529 ₫ total
includes taxes & fees
17 Dec - 18 Dec
Stella d'Italia
Classic Apartment, 2 Bedrooms (Giglio Viola) | Living area | Flat-screen TV
Canto degli Scali

Canto degli Scali

Canto degli Scali
San Giovanni, 0.6 km from Piazza Santo Spirito
10.0 out of 10, Exceptional, (236)
"Amazing. Just incredible. Everyone should stay here when the come to Florence!"
Canada
Melissa
Canto degli Scali
Desk, soundproofing, free cots/infant beds, rollaway beds
Soprarno Suites

Soprarno Suites

Soprarno Suites
Historic Centre of Florence, 0.1 km from Piazza Santo Spirito
9.8 out of 10, Exceptional, (394)
"Beautiful rooms in ideal location and staff was friendly and helpful"
Canada
Dara
The price is 5.028.478 ₫
5.963.702 ₫ total
includes taxes & fees
17 Dec - 18 Dec
Soprarno Suites
Premium Double Room, Annex Building (in the garden) | Down duvets, in-room safe, individually decorated, desk
AdAstra Suites

AdAstra Suites

AdAstra Suites
San Frediano, 0.2 km from Piazza Santo Spirito
9.8 out of 10, Exceptional, (221)
"Great Room - Lovely breakfast excellent strong Cappuccino and lovely yoghurts. Thanks see you soon. "
United Kingdom
Tim
The price is 4.775.791 ₫
5.685.746 ₫ total
includes taxes & fees
17 Dec - 18 Dec
AdAstra Suites
Comfort Double Room, Private Bathroom, Courtyard View | Courtyard view
Drom Florence Rooms & Apartments

Drom Florence Rooms & Apartments

Drom Florence Rooms & Apartments
San Frediano, 0.5 km from Piazza Santo Spirito
9.8 out of 10, Exceptional, (136)
"Ver clean and quiet, wonderful stay."
United States
kevin
Drom Florence Rooms & Apartments
Exterior
Portrait Firenze - Lungarno Collection

Portrait Firenze - Lungarno Collection

Portrait Firenze - Lungarno Collection
5.0 star property
San Giovanni, 0.5 km from Piazza Santo Spirito
9.8 out of 10, Exceptional, (302)
"Great location and got fantastic service from the hotel. Room was very clean and comfortable. Definitely my first choice for staying in Firenze!"
Canada
LEI
The price is 23.640.306 ₫
26.498.481 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Portrait Firenze - Lungarno Collection
Deluxe Double Room, Balcony | View from room
Hotel Milu Florence

Hotel Milu Florence

Hotel Milu Florence
4.0 star property
San Giovanni, 0.6 km from Piazza Santo Spirito
9.8 out of 10, Exceptional, (605)
"Great location, nice breakfast, and staff was great. "
United States
Rene
The price is 3.259.667 ₫
4.481.271 ₫ total
includes taxes & fees
17 Dec - 18 Dec
Hotel Milu Florence
Lobby
Hotel Horto Convento

Hotel Horto Convento

Hotel Horto Convento
4.0 star property
San Frediano, 0.7 km from Piazza Santo Spirito
9.8 out of 10, Exceptional, (599)
"Excellent stay"
United States
Renata
The price is 3.136.692 ₫
3.882.737 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Hotel Horto Convento
Exterior
Numa Florence Palazzo Belfiore

Numa Florence Palazzo Belfiore

Numa Florence Palazzo Belfiore
Historic Centre of Florence, 0.2 km from Piazza Santo Spirito
9.6 out of 10, Exceptional, (371)
"Great property, plenty of space for my family. The location is great, we were able to walk everywhere including the train station. "
United States
Loren
The price is 3.401.892 ₫
4.113.195 ₫ total
includes taxes & fees
18 Dec - 19 Dec
Numa Florence Palazzo Belfiore
Aerial view
Ponte Vecchio Suites & Spa

Ponte Vecchio Suites & Spa

Ponte Vecchio Suites & Spa
4.0 star property
Historic Centre of Florence, 0.4 km from Piazza Santo Spirito
9.6 out of 10, Exceptional, (1001)
"The entire staff was so warm and welcoming. The morning breakfasts were a great way to start each day. I would highly recommend anyone looking for a hotel to give this great place a try. "
United States
Michael
Ponte Vecchio Suites & Spa
Exterior
Hotel Lungarno - Lungarno Collection

Hotel Lungarno - Lungarno Collection

Hotel Lungarno - Lungarno Collection
5.0 star property
Historic Centre of Florence, 0.4 km from Piazza Santo Spirito
9.6 out of 10, Exceptional, (600)
"Excellent location! Truly a 5 star hotel ! Great service, breakfast, and service . Bedrooms were clean! Bathrooms were excellent!"
Canada
Pam
The price is 15.442.005 ₫
17.480.349 ₫ total
includes taxes & fees
17 Dec - 18 Dec
Hotel Lungarno - Lungarno Collection
Suite (Panoramic) | View from room
Antica Torre di Via Tornabuoni 1

Antica Torre di Via Tornabuoni 1

Antica Torre di Via Tornabuoni 1
Duomo, 0.5 km from Piazza Santo Spirito
9.6 out of 10, Exceptional, (582)
"Incredible location and services!"
United States
William
Antica Torre di Via Tornabuoni 1
Food court
Leone Blu Suites | UNA Esperienze

Leone Blu Suites | UNA Esperienze

Leone Blu Suites | UNA Esperienze
Duomo, 0.5 km from Piazza Santo Spirito
9.6 out of 10, Exceptional, (195)
"We had a wonderful stay. Service was impeccable. Wonderful breakfast is recommended. Great location, comfortable bed and plenty of hot water pressure."
United States
Peter
The price is 5.980.267 ₫
7.010.670 ₫ total
includes taxes & fees
17 Dec - 18 Dec
Leone Blu Suites | UNA Esperienze
Rooftop terrace
IL Tornabuoni The Unbound Collection by Hyatt

IL Tornabuoni The Unbound Collection by Hyatt

IL Tornabuoni The Unbound Collection by Hyatt
5.0 star property
Duomo, 0.6 km from Piazza Santo Spirito
9.6 out of 10, Exceptional, (107)
"Great location and very helpful and friendly staff. "
United States
Sheru
The price is 9.124.681 ₫
10.531.448 ₫ total
includes taxes & fees
21 Dec - 22 Dec
IL Tornabuoni The Unbound Collection by Hyatt
Superior Double Room | Down duvets, minibar, in-room safe, desk
Davanzati

Davanzati

Davanzati
3.0 star property
San Giovanni, 0.6 km from Piazza Santo Spirito
9.6 out of 10, Exceptional, (886)
"Great location "
Canada
Brent
The price is 3.035.056 ₫
3.709.170 ₫ total
includes taxes & fees
19 Dec - 20 Dec
Davanzati
Terrace/patio
Hotel degli Orafi

Hotel degli Orafi

Hotel degli Orafi
4.0 star property
San Giovanni, 0.6 km from Piazza Santo Spirito
9.6 out of 10, Exceptional, (1002)
"Fantastic location, helpful staff, terrific breakfast, clean rooms"
United States
Michael
The price is 7.959.651 ₫
9.187.993 ₫ total
includes taxes & fees
14 Jan - 15 Jan 2026
Hotel degli Orafi
Bar (on property)
Golden Tower Hotel & Spa

Golden Tower Hotel & Spa

Golden Tower Hotel & Spa
5.0 star property
San Giovanni, 0.6 km from Piazza Santo Spirito
9.6 out of 10, Exceptional, (954)
"Amazing location and top class staff."
United Kingdom
Gabriella De
The price is 6.443.527 ₫
7.582.024 ₫ total
includes taxes & fees
6 Jan - 7 Jan 2026
Golden Tower Hotel & Spa
Garden
Al Palazzo del Marchese di Camugliano

Al Palazzo del Marchese di Camugliano

Al Palazzo del Marchese di Camugliano
Duomo, 0.6 km from Piazza Santo Spirito
9.6 out of 10, Exceptional, (342)
"Great staff and an incredible property"
Canada
John
Al Palazzo del Marchese di Camugliano
Royal Suite, 1 King Bed, Balcony, River View | Premium bedding, down duvets, minibar, in-room safe
The St. Regis Florence

The St. Regis Florence

The St. Regis Florence
5.0 star property
Santa Maria Novella, 0.7 km from Piazza Santo Spirito
9.6 out of 10, Exceptional, (264)
"Our stay was amazing, the room was great and the staff was fantastic! "
United States
Anonymous traveller
The price is 17.688.115 ₫
19.951.070 ₫ total
includes taxes & fees
6 Jan - 7 Jan 2026
The St. Regis Florence
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Piazza Santo Spirito Hotel Reviews

Hotels near other Piazza Santo Spirito attractions

Santo Spirito Basilica

Learn about the local history of Florence when you take a trip to Santo Spirito Basilica. Stroll along the riverfront or visit the churches in this vibrant area.
See properties

Pitti Vintage

You can browse for the perfect souvenirs at Pitti Vintage during your trip to Florence. Stroll along the riverfront or visit the notable monuments in this vibrant area.
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Frequently asked questions

What's the area like around Piazza Santo Spirito?
Piazza Santo Spirito is located in a historic area of Florence known for its stunning cathedral and popular art scene. If you're looking for a convenient place to stay, take a look at the 3050 hotels and other accommodation options you'll find within a mile.
How many hotels will I find close to Piazza Santo Spirito?
Expedia has 3050 hotels and other accommodation options within a mile from Piazza Santo Spirito.
If I need to cancel the hotel reservation for my stay near Piazza Santo Spirito, will I receive a refund?
Yes! You'll find that most hotel reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you have a non-refundable reservation, you might be able to still cancel and receive a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then filter by "fully refundable" to get the best deals near Piazza Santo Spirito.
What can I see and do near Piazza Santo Spirito?
Study the collections at Uffizi Gallery, Galileo Museum - Institute and Museum of the History of Science or Basilica of Santa Maria Novella. Pitti Palace, Via de' Tornabuoni and Ponte Vecchio are landmarks that you won't want to miss. You can check out the local talent at Teatro Verdi, Visarno Arena and Teatro Comunale Florence.
How can I get to Piazza Santo Spirito?
With so many ways to get around, seeing all of the area near Piazza Santo Spirito is easy. Nearby metro stations include Unità Tram Stop, Valfonda - Stazione Santa Maria Novella Tram Stop and San Marco University Tram Stop. If you're taking a train into town, Florence (ZMS-Santa Maria Novella Train Station) and Florence Santa Maria Novella Station are the closest stops to Historic Centre of Florence.

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