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Check availability on Rome City Centre Business Hotels

Our top choices for Rome City Centre business-friendly hotels

Hypo-allergenic bedding, down duvets, in-room safe
UNA Hotels Decò Roma

UNA Hotels Decò Roma

UNA Hotels Decò Roma
4.0 star property
Rome City Centre
9.2 out of 10, Wonderful, (1528)
"The staff was great, the Breakfast was delicious, the The room was spotless and for me close to the termine is perfect "
United States
Norma
The price is 4.183.380 ₫
5.064.977 ₫ total
includes taxes & fees
14 Dec - 15 Dec
UNA Hotels Decò Roma
Exterior
Hotel Quirinale

Hotel Quirinale

Hotel Quirinale
4.0 star property
Rome City Centre
8.6 out of 10, Excellent, (1912)
"Very nice stay. "
United States
Monique
The price is 3.378.315 ₫
4.179.406 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
Hotel Quirinale
Exterior
iQ Hotel Roma

iQ Hotel Roma

iQ Hotel Roma
4.0 star property
Rome City Centre
9.8 out of 10, Exceptional, (1418)
"Modern hotel with centric location, rooms had good space, great service, very clean and safe. The breakfasts buffet is adequately priced with many options. This is my favorite hotel in Rome so far!"
United States
Jorge
The price is 3.014.279 ₫
3.778.967 ₫ total
includes taxes & fees
11 Jan - 12 Jan 2026
iQ Hotel Roma
Food and drink
Best Western Plus Hotel Universo

Best Western Plus Hotel Universo

Best Western Plus Hotel Universo
4.0 star property
Rome City Centre
9.2 out of 10, Wonderful, (1573)
"Great rooms great service"
Germany
Samir
The price is 3.653.354 ₫
4.482.453 ₫ total
includes taxes & fees
12 Jan - 13 Jan 2026
Best Western Plus Hotel Universo
Front of property – evening/night
Hotel Artemide

Hotel Artemide

Hotel Artemide
4.0 star property
Rome City Centre
9.8 out of 10, Exceptional, (1006)
"We had a great stay!"
United States
Terry
The price is 4.749.433 ₫
5.688.079 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Hotel Artemide
Property grounds
Hotel Colosseum

Hotel Colosseum

Hotel Colosseum
3.0 star property
Rome City Centre
8.8 out of 10, Excellent, (1000)
"The staff was so helpful and nice! Breakfast was wonderful. I would definitely stay again!!"
United States
Linda
The price is 3.344.275 ₫
4.049.664 ₫ total
includes taxes & fees
17 Dec - 18 Dec
Hotel Colosseum
Premium bedding, minibar, in-room safe, desk
Hotel Sonya

Hotel Sonya

Hotel Sonya
3.0 star property
Rome City Centre
8.2 out of 10, Very good, (1000)
"Great stay, very accommodating "
United States
john
The price is 1.798.546 ₫
2.349.424 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Hotel Sonya
Suite (La Dolce Vita) | View from room
Hotel Nazionale

Hotel Nazionale

Hotel Nazionale
4.0 star property
Rome City Centre
9.6 out of 10, Exceptional, (1002)
"The room was spotless and the staff was extremely helpful."
United States
Diane
Hotel Nazionale
Terrace/patio
Hotel Nord Nuova Roma

Hotel Nord Nuova Roma

Hotel Nord Nuova Roma
3.0 star property
Rome City Centre
8.6 out of 10, Excellent, (1005)
"Perfect stay!!!!"
United States
Laurel
The price is 3.210.116 ₫
3.902.089 ₫ total
includes taxes & fees
6 Jan - 7 Jan 2026
Hotel Nord Nuova Roma
Outdoor dining
Hotel Delle Nazioni

Hotel Delle Nazioni

Hotel Delle Nazioni
4.0 star property
Rome City Centre
9.0 out of 10, Wonderful, (1003)
"Clean room, good service and excellent breakfast"
Canada
Bassam
Hotel Delle Nazioni
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Rome City Centre Hotel Reviews

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Frequently asked questions

How much do business-friendly hotels in Rome City Centre cost?
You can expect to pay between 2.349.424 ₫ and 5.688.079 ₫ per night for business-friendly hotels in Rome City Centre. Terrific deals on properties that are suitable for corporate travellers are a few clicks away on Expedia. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
How many business-friendly hotels are there in Rome City Centre?
When your job takes you on the road in Rome City Centre, you'll have 265 business-friendly hotels to select from.
Why book your business-friendly hotel in Rome City Centre with Expedia?
At Expedia, we make it our business to help you land the perfect stay at the right price. From fancy, corporate-friendly getaways to affordable hotels loaded with conveniences, you'll have your next work trip organised in just a few clicks.
How can I find cheap business-friendly hotels in Rome City Centre?
Select the "business friendly" filter, listed just under the "traveller experience" heading, to find cheap business-friendly hotels in Rome City Centre. Then narrow your search by your preferred hotel star rating and budget. Staying outside the city centre is another good way to save.