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Our top choices for Rome City Centre business-friendly hotels

Hotel Quirinale

Hotel Quirinale
4.0 star property
Rome City Centre
8.6 out of 10, Excellent, (1919)
"Super helpful staff and breakfast was lovely. Great location."
United Kingdom
Claire
The price is 3.370.637 ₫
4.169.908 ₫ total
includes taxes & fees
18 Jan - 19 Jan 2026
Hotel Quirinale

UNA Hotels Decò Roma

UNA Hotels Decò Roma
4.0 star property
Rome City Centre
9.2 out of 10, Wonderful, (1533)
"If you must stay next to the train station this was perfect. "
United States
Anthony
The price is 4.173.872 ₫
5.053.466 ₫ total
includes taxes & fees
24 Dec - 25 Dec
UNA Hotels Decò Roma

iQ Hotel Roma

iQ Hotel Roma
4.0 star property
Rome City Centre
9.8 out of 10, Exceptional, (1412)
" The buffet breakfast was very good , and their staff with excellent service ."
United States
JASMIN
The price is 2.829.269 ₫
3.574.402 ₫ total
includes taxes & fees
21 Dec - 22 Dec
iQ Hotel Roma

Best Western Plus Hotel Universo

Best Western Plus Hotel Universo
4.0 star property
Rome City Centre
9.2 out of 10, Wonderful, (1577)
"Great rooms great service"
Germany
Samir
The price is 3.788.312 ₫
4.630.160 ₫ total
includes taxes & fees
18 Jan - 19 Jan 2026
Best Western Plus Hotel Universo

Hotel Sonya

Hotel Sonya
3.0 star property
Rome City Centre
8.2 out of 10, Very good, (1001)
"Great stay, very accommodating "
United States
john
The price is 1.792.804 ₫
2.341.850 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Hotel Sonya

Hotel Colosseum

Hotel Colosseum
3.0 star property
Rome City Centre
8.8 out of 10, Excellent, (1000)
"Nice people, nice place. Highly recommend "
Australia
Laz
The price is 2.773.244 ₫
3.420.334 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Hotel Colosseum

Hotel Delle Nazioni

Hotel Delle Nazioni
4.0 star property
Rome City Centre
9.0 out of 10, Wonderful, (1001)
"It was a nice place to stay and breakfast was amazing. Rooms were clean and quiet. Close to most of attractions and there was a Taxi station next to the hotel."
United States
Rommel
Hotel Delle Nazioni

Hotel Artemide

Hotel Artemide
4.0 star property
Rome City Centre
9.8 out of 10, Exceptional, (1003)
"We had a great stay!"
United States
Terry
The price is 3.781.696 ₫
4.622.073 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Hotel Artemide

Hotel Scalinata di Spagna

Hotel Scalinata di Spagna
3.0 star property
Rome City Centre
9.2 out of 10, Wonderful, (1002)
"Great location, facilities are very good with great staff"
United States
Daniel
The price is 3.918.041 ₫
4.680.165 ₫ total
includes taxes & fees
9 Jan - 10 Jan 2026
Hotel Scalinata di Spagna

Starhotels Metropole

Starhotels Metropole
4.0 star property
Rome City Centre
8.8 out of 10, Excellent, (1001)
"Staff was very friendly, the rooms very clean and comfortable, and the included breakfast was delicious. "
United States
Sabrina
The price is 4.762.135 ₫
5.700.555 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Starhotels Metropole
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Rome City Centre Hotel Reviews

Frequently asked questions

How much do business-friendly hotels in Rome City Centre cost?
You can expect to pay between 2.341.850 ₫ and 5.700.555 ₫ per night for business-friendly hotels in Rome City Centre. Terrific deals on properties that are suitable for corporate travellers are a few clicks away on Expedia. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
How many business-friendly hotels are there in Rome City Centre?
When your job takes you on the road in Rome City Centre, you'll have 265 business-friendly hotels to select from.
Why book your business-friendly hotel in Rome City Centre with Expedia?
At Expedia, we make it our business to help you land the perfect stay at the right price. From fancy, corporate-friendly getaways to affordable hotels loaded with conveniences, you'll have your next work trip organised in just a few clicks.
How can I find cheap business-friendly hotels in Rome City Centre?
Select the "business friendly" filter, listed just under the "traveller experience" heading, to find cheap business-friendly hotels in Rome City Centre. Then narrow your search by your preferred hotel star rating and budget. Staying outside the city centre is another good way to save.