Saint James City Holiday Rentals, Florida: Private House Rentals

A marina with boats docked, a house, and palm trees.

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Our top choices for Saint James City hotels

A balcony with a wooden table and chairs, a hanging chair, and a view of palm trees and a pool.

A beachfront hotel with palm trees, a sandy walkway, and a pool.

A modern kitchen with grey cabinets, a stainless steel refrigerator, a microwave, and a sink. There is a painting of a flamingo on the wall.

A resort with a pool, thatched umbrellas, and palm trees.

1. Off the Charts Inn & Out Island Resort

Saint James City

Lisa

3.502.283 ₫

4.775.348 ₫ total

includes taxes & fees

23 Sept - 24 Sept

A Holiday Inn Express building with a modern design, featuring a flat facade and a covered entrance area.

A coffee station with two coffee machines and a variety of coffee pods and cups.

A poolside area with lounge chairs, a pool, and a fence.

A hotel room with a bed, desk, chair, TV, and a bathroom visible through an open door.

2. Holiday Inn Express & Suites Fort Myers Airport by IHG

Daniels Corridor

Brandon

3.070.360 ₫

3.423.451 ₫ total

includes taxes & fees

30 Sept - 1 Oct

A modern hotel lobby with wooden flooring, blue and beige chairs, and a patterned rug.

A pool area with lounge chairs, a gazebo, and a blue umbrella.

A hotel lobby with a reception desk, a seating area with a sofa and chairs, a kitchenette, and a 'Welcome to Hampton' sign.

A modern lounge area with a sofa, two yellow ottomans, a small round table, and a printer on a wooden side table.

3. Hampton Inn Fort Myers-Airport & I-75

Daniels Corridor

John

1.898.794 ₫

2.117.155 ₫ total

includes taxes & fees

7 Oct - 8 Oct

A hotel with a covered entrance, palm trees, and a well-maintained garden.

A compact hotel room with a kitchenette, a dining area, a TV, and a seating area with a view of the outdoors.

An outdoor grill station with a stone base, a built-in seating area, and a view of a residential building in the background.

A spacious lobby with a patterned carpet, a seating area with sofas and chairs, and a visible kitchen in the background.

4. Homewood Suites by Hilton - Fort Myers

Villas

Iris

2.667.050 ₫

2.973.761 ₫ total

includes taxes & fees

28 Sept - 29 Sept

An indoor swimming pool with clear water, a lifeguard station, and a seating area with chairs.

A hotel room with two beds, a desk, a TV, and a window with curtains.

A Comfort Inn & Suites hotel with a covered entrance, palm trees, and a well-lit facade.

A reception desk with a sign reading "Comfort Inn & Suites" and two monitors on either side.

5. Comfort Inn & Suites Fort Myers Airport

Daniels Corridor

Susan

1.704.830 ₫

1.900.886 ₫ total

includes taxes & fees

27 Sept - 28 Sept

A spacious lobby with a staircase, seating area, and a large wall-mounted screen.

A hotel room with two beds, a desk, and a chair.

A hotel lobby with a reception desk, seating area, and a restaurant.

A gym with treadmills, elliptical machines, and a stationary bike.

6. Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park

Daniels Corridor

Renny

1.709.383 ₫

1.905.962 ₫ total

includes taxes & fees

24 Sept - 25 Sept

A modern kitchen with a marble countertop, wooden cabinets, and a built-in pantry.

A multi-story hotel with a prominent "Hyatt Place" sign, surrounded by palm trees and a well-maintained lawn.

A beach at sunset with calm waters reflecting the sky.

A blue woven chair with a cushion, a small round table, and a tall floor lamp with two spherical lights.

7. Hyatt Place Fort Myers Estero

Estero

Gianfranco

2.410.568 ₫

2.687.782 ₫ total

includes taxes & fees

25 Sept - 26 Sept

A hotel with a modern design, featuring a prominent 'Best Western' sign, multiple parking spaces, and palm trees.

A hotel room with a TV, sofa, coffee table, desk, and a bathroom visible in the background.

A breakfast buffet with various food options, including cereals, pastries, and a sign indicating gluten-free items.

A pool area with lounge chairs and umbrellas, surrounded by palm trees and a building.

8. Best Western Fort Myers Inn & Suites

Fort Myers

William

1.709.774 ₫

1.906.398 ₫ total

includes taxes & fees

27 Sept - 28 Sept

A hotel pool area with multiple lounge chairs and umbrellas, surrounded by a fence and palm trees.

A reception area with a beach view mural, a staircase, and a reception desk.

A modern lobby with a white brick wall, a flat-screen TV, and colorful abstract paintings. There are several seating areas with different styles of chairs.

A modern lobby with a fireplace, seating area, and artwork.

9. La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

Fort Myers

Jorge

1.852.482 ₫

2.065.517 ₫ total

includes taxes & fees

29 Sept - 30 Sept

A hotel room with a bed, a desk, a chair, and a small table.

A hotel with a curved entrance, multiple floors, and a parking area.

A modern kitchen with wooden cabinets, a built-in sink, and a coffee maker.

A swimming pool with lounge chairs and umbrellas, surrounded by palm trees and a building with a blue and white facade.

10. SpringHill Suites by Marriott Fort Myers Airport

Daniels Corridor

Michael

2.786.528 ₫

3.106.979 ₫ total

includes taxes & fees

28 Sept - 29 Sept

An outdoor seating area with a fire pit, outdoor furniture, and a covered patio.

A modern hotel room with a bed, bedside tables, a lamp, a nightstand, a built-in kitchen with a refrigerator, microwave, and cabinets.

A multi-story hotel with a modern design, featuring a central entrance with a covered area and a parking lot with marked spaces.

A modern kitchen with wooden cabinets, a white countertop, and a fruit basket.

11. TownePlace Suites by Marriott Fort Myers Gulf Coast

Fort Myers

Andrei

2.575.782 ₫

2.871.996 ₫ total

includes taxes & fees

9 Oct - 10 Oct

A hotel room with two beds, a wooden headboard, a nightstand with a lamp, and a window with curtains.

A coffee station with multiple dispensers, a sign above stating 'MUST HAVE COFFEE.', and various coffee products on display.

A coffee station with two coffee machines, a coffee press, and various coffee cups and containers.

A modern office space with two desks, each equipped with a computer monitor, keyboard, and mouse. There is a framed artwork on the wall above the desks.

12. Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Caloosahatchee

john

2.679.854 ₫

2.988.167 ₫ total

includes taxes & fees

4 Oct - 5 Oct

An outdoor patio with a fire pit, green chairs, a red umbrella, and a bar area.

A hotel with a swimming pool, outdoor seating, and a sign indicating a 5 ft depth limit.

A spacious lobby with a central seating area, a reception desk, and a vending machine.

A modern hotel with a covered entrance, multiple floors, and a landscaped area with plants and outdoor seating.

13. Home2 Suites by Hilton Fort Myers Colonial Blvd

Fort Myers

Jackie

3.072.205 ₫

3.425.508 ₫ total

includes taxes & fees

28 Sept - 29 Sept

A modern hotel lobby with a wooden floor, leather armchairs, a round table, and a large abstract painting on the wall.

A modern kitchen area with a bar counter, seating, and a coffee station.

A hotel room with two beds, wooden headboards, white bedding, a nightstand, a lamp, and a window with a view.

A modern kitchen with a microwave, sink, and wooden shelves.

14. Extended Stay America Premier Suites - Fort Myers - Airport

Daniels Corridor

Robert

1.428.238 ₫

1.592.164 ₫ total

includes taxes & fees

23 Sept - 24 Sept

A multi-level hotel atrium with balconies, seating areas, and a central courtyard.

An outdoor patio with wicker furniture, potted plants, and a view of a building with large windows.

A hotel with a red facade, multiple floors, and palm trees in the foreground.

A modern indoor pool area with a central water feature, surrounded by stone walls and minimalist decor.

15. Embassy Suites by Hilton Fort Myers Estero

Estero

Roberto

2.752.184 ₫

3.068.686 ₫ total

includes taxes & fees

28 Sept - 29 Sept

A hotel room with a bed, a desk with a chair, a television, and a door.

A gym with treadmills, a mirrored wall, and a wooden floor.

A hotel with a swimming pool, outdoor seating, and a covered patio area.

A modern kitchen with a central island, wooden cabinets, and a blue accent wall.

16. Drury Inn & Suites Fort Myers Airport FGCU

Miromar Lakes

Mark

2.861.720 ₫

3.190.818 ₫ total

includes taxes & fees

26 Sept - 27 Sept

A multi-story hotel with a clear sky, palm trees, and a sign reading "HYATT PLACE".

A bakery counter with pastries and a beverage display.

A hotel room with a sofa, a bed, a desk, and a TV.

17. Hyatt Place Fort Myers/at The Forum

The Forum

Lynette

2.185.512 ₫

2.436.846 ₫ total

includes taxes & fees

29 Sept - 30 Sept

An outdoor patio with wicker furniture, a fire feature, and string lights.

A modern kitchen with a central island, bar stools, and hanging pendant lights.

A hotel with a clear entrance, a covered waiting area, and a sign indicating a clearance height of 10'-3".

A pool area with a hot tub, lounge chairs, and palm trees.

18. Hilton Garden Inn Ft Myers

Villas

Hoyle

2.268.944 ₫

2.529.872 ₫ total

includes taxes & fees

27 Sept - 28 Sept

An outdoor patio area with round tables and chairs, ceiling fans, and a bar area with shelves of bottles.

An outdoor patio area with tables and chairs, string lights, and potted plants.

A modern reception area with a large abstract mural, a wooden reception desk, and a seating area with a long table and chairs.

A swimming pool with a stone wall and palm trees, surrounded by a building with large windows and outdoor seating.

19. Doubletree by Hilton Fort Myers at Bell Tower Shops

Villas

heather

2.752.184 ₫

3.068.686 ₫ total

includes taxes & fees

8 Oct - 9 Oct

A modern hotel lobby with a seating area, a bar, and a television.

A hotel courtyard with a swimming pool, lounge chairs, and palm trees.

A modern hotel room with a grey sofa, a small table, a TV, and a large window with curtains.

An outdoor patio area with wicker furniture, a table, and chairs, surrounded by brick walls and palm trees.

20. Courtyard by Marriott Fort Myers Cape Coral

Fort Myers

Henry

2.318.204 ₫

2.584.798 ₫ total

includes taxes & fees

5 Oct - 6 Oct

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Where to stay in Saint James City

Find the best Saint James City areas for the activities you enjoy most.

Manatee Bay

Manatee Bay

Though Manatee Bay may not have many top sights, you can venture to the surrounding area to see attractions like Harbour View Gallery and Rumrunners.

See properties

Learn more about Saint James City

Rent a boat to explore Pine Island's mangrove-lined waterways where dolphins often play alongside fishing enthusiasts. Savour fresh-caught seafood at waterfront restaurants while watching spectacular Gulf Coast sunsets that paint the sky in vibrant colours.

See all hotels in Saint James City

A beach with a wooden pier extending into the ocean, palm trees, and a sunset sky.

Top Saint James City Hotel Reviews

Lani Kai Beachfront Resort

10/10 Excellent

"Excellent hotel and location, clean, friendly staff, good vibes, delicious and affordable food. We’ll back."

Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway

8/10 Good

"This was close to our destination and always clean and friendly folks."

Sanibel Island Beach Resort

10/10 Excellent

"I recently enjoyed an unforgettable stay in Sanibel Island, and it was everything I could have hoped for in a beach getaway. From the moment I arrived, the warm, laid-back atmosphere and friendly staff made me feel instantly at home. The highlight was definitely the direct beach access — just a few steps from my room, I was on soft white sand, with the gentle sound of waves and endless seashells scattered along the shore. The accommodations were clean, comfortable, and thoughtfully designed for relaxation. On-site amenities — including a pool, beach loungers, and a cozy bar — made it easy to unwind without ever leaving the property. Sanibel’s charm lies in its natural beauty and peaceful vibe, and this stay captured that perfectly. Whether you’re looking to shell hunt, bike along scenic trails, or simply soak up the sun, this is the kind of place that makes you want to come back year after year. The restaurant was 10/10- My coffee was perfect every morning thanks to Ashley! Would for sure come back again!"

Hampton Inn Fort Myers-Airport & I-75

10/10 Excellent

"Extremely clean property, great room, lovely people. Really great breakfast. Will stay there again without a doubt."

Holiday Inn Express Cape Coral-Fort Myers Area by IHG

10/10 Excellent

"Very clean. Breakfast and pool were an added touch! Loved to coffee too!"

Margaritaville Beach Resort Fort Myers

10/10 Excellent

"El parqueo debe estar incluido"

DiamondHead Beach Resort

10/10 Excellent

"Staff was awesome! we had a wonderful quick beach trip with you guys, thank you!"

Hilton Garden Inn Ft Myers

10/10 Excellent

"Everything is really good"

Quality Inn Fort Myers Cape Coral

10/10 Excellent

"Everything was good The room was clean. The staff was a very friendly and helpful. Parking has lot of space to park even a big car. The most important was breakfast eaten in the morning without leaving the hotel. I strongly recomend for everybody in the future."

More cheap stays in Saint James City

Quality Inn Fort Myers Cape Coral

4760 S Cleveland Ave Fort Myers FL

1.202.422 ₫

1.503.027 ₫ total

4 Oct - 5 Oct

includes taxes & fees

7.4/10 Good! (466 reviews)

Baymont by Wyndham Fort Myers Central

4850 S Cleveland Ave Fort Myers FL

1.365.945 ₫

1.523.094 ₫ total

26 Sept - 27 Sept

includes taxes & fees

Extended Stay America Premier Suites - Fort Myers - Airport

14761 Hope Center Loop Fort Myers FL

1.545.209 ₫

1.722.912 ₫ total

29 Sept - 30 Sept

includes taxes & fees

9/10 Wonderful! (1,125 reviews)

Comfort Inn & Suites Fort Myers Airport

Fort Myers FL

1.704.830 ₫

1.900.886 ₫ total

27 Sept - 28 Sept

includes taxes & fees

8.8/10 Excellent! (1,152 reviews)

Holiday Inn Express Cape Coral-Fort Myers Area by IHG

1538 Cape Coral Pkwy E Cape Coral FL

2.679.854 ₫

2.988.167 ₫ total

4 Oct - 5 Oct

includes taxes & fees

9.4/10 Exceptional! (1,670 reviews)

Holiday Inn Express & Suites Fort Myers Airport by IHG

14567 GLOBAL PARKWAY Fort Myers FL

3.070.360 ₫

3.423.451 ₫ total

30 Sept - 1 Oct

includes taxes & fees

9.6/10 Exceptional! (1,204 reviews)

Hotels in Saint James City with star rating

Frequently asked questions

What's the seasonal weather in Saint James City?

The hottest months are usually August and July, with an average temperature of 28°C, while the coldest months are January and February, with an average of 20°C. The rainiest months in Saint James City are August, June, September and July, with each month seeing an average of 178 mm of rainfall.

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Find hotels in Saint James City, FL from 1.503.027 ₫

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Saint James City

Check prices for these dates

Filter by

Star rating

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Our top choices for Saint James City hotels

1. Off the Charts Inn & Out Island Resort

2. Holiday Inn Express & Suites Fort Myers Airport by IHG

3. Hampton Inn Fort Myers-Airport & I-75

4. Homewood Suites by Hilton - Fort Myers

5. Comfort Inn & Suites Fort Myers Airport

6. Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park

7. Hyatt Place Fort Myers Estero

8. Best Western Fort Myers Inn & Suites

9. La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

10. SpringHill Suites by Marriott Fort Myers Airport

11. TownePlace Suites by Marriott Fort Myers Gulf Coast

12. Holiday Inn Express Cape Coral-Fort Myers Area by IHG

13. Home2 Suites by Hilton Fort Myers Colonial Blvd

14. Extended Stay America Premier Suites - Fort Myers - Airport

15. Embassy Suites by Hilton Fort Myers Estero

16. Drury Inn & Suites Fort Myers Airport FGCU

17. Hyatt Place Fort Myers/at The Forum

18. Hilton Garden Inn Ft Myers

19. Doubletree by Hilton Fort Myers at Bell Tower Shops

20. Courtyard by Marriott Fort Myers Cape Coral

Where to stay in Saint James City

Manatee Bay

Learn more about Saint James City

Top Saint James City Hotel Reviews

Lani Kai Beachfront Resort

Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway

Sanibel Island Beach Resort

Hampton Inn Fort Myers-Airport & I-75

Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Margaritaville Beach Resort Fort Myers

DiamondHead Beach Resort

Hilton Garden Inn Ft Myers

Quality Inn Fort Myers Cape Coral

More cheap stays in Saint James City

Quality Inn Fort Myers Cape Coral

Baymont by Wyndham Fort Myers Central

Extended Stay America Premier Suites - Fort Myers - Airport

Comfort Inn & Suites Fort Myers Airport

Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Holiday Inn Express & Suites Fort Myers Airport by IHG

Hotels in Saint James City with star rating

Frequently asked questions

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