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11 Dec - 12 Dec
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12 Dec - 13 Dec
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12 Dec - 14 Dec
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19 Dec - 21 Dec

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Our top choices for San Antón hotels

International cuisine, al fresco dining
Gran Hotel Europa Santo Domingo, Trademark by Wyndham

Gran Hotel Europa Santo Domingo, Trademark by Wyndham

Gran Hotel Europa Santo Domingo, Trademark by Wyndham
3.5 star property
San Antón
8.8 out of 10, Excellent, (893)
"Great location! "
United States
Valeska
The price is 2.307.555 ₫
2.953.671 ₫ total
includes taxes & fees
13 Dec - 14 Dec
Gran Hotel Europa Santo Domingo, Trademark by Wyndham
2 bars/lounges
Empyrean Art Deco

Empyrean Art Deco

Empyrean Art Deco
3.0 star property
San Antón
9.2 out of 10, Wonderful, (83)
"Everything good!"
United States
milton
The price is 1.604.508 ₫
2.259.148 ₫ total
includes taxes & fees
13 Dec - 14 Dec
Empyrean Art Deco
Terrace/patio
Aparta Hotel Tiempo

Aparta Hotel Tiempo

Aparta Hotel Tiempo
2.0 star property
San Antón
The price is 746.428 ₫
880.785 ₫ total
includes taxes & fees
19 Dec - 20 Dec
Aparta Hotel Tiempo
1 bedroom, in-room safe, desk, free WiFi
Diamonds Hotel Boutique

Diamonds Hotel Boutique

Diamonds Hotel Boutique
2.5 star property
San Antón
The price is 1.448.095 ₫
1.853.562 ₫ total
includes taxes & fees
24 Dec - 25 Dec
Diamonds Hotel Boutique
Basic Apartment, 2 Bedrooms, Non Smoking, Air conditioning | Living area | 40-inch Smart TV with digital channels, streaming services
Casa de mabel

Casa de mabel

Casa de mabel
3.0 star property
San Antón
The price is 2.606.571 ₫
3.075.754 ₫ total
includes taxes & fees
24 Dec - 25 Dec
Casa de mabel
Outdoor pool, pool umbrellas, pool loungers
W&P Santo Domingo

W&P Santo Domingo

W&P Santo Domingo
4.0 star property
Bella Vista, 5.9 km from San Antón
9.2 out of 10, Wonderful, (1160)
"The location, room, food and staff were fantastic! "
United States
Sandy
W&P Santo Domingo
Property amenity
El Embajador, a Royal Hideaway Hotel

El Embajador, a Royal Hideaway Hotel

El Embajador, a Royal Hideaway Hotel
5.0 star property
Bella Vista, 5.7 km from San Antón
9.2 out of 10, Wonderful, (1293)
"Great stay "
United States
Nelson
The price is 2.725.792 ₫
3.489.014 ₫ total
includes taxes & fees
30 Dec - 31 Dec
El Embajador, a Royal Hideaway Hotel
Premium bedding, down duvets, pillow-top beds, minibar
Catalonia Santo Domingo

Catalonia Santo Domingo

Catalonia Santo Domingo
5.0 star property
Ciudad Universitaria, 3.4 km from San Antón
8.8 out of 10, Excellent, (1729)
"Everything was great, very clean, good food, excelent amenities."
United States
FELIX
The price is 2.738.216 ₫
3.504.916 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Catalonia Santo Domingo
Premium Suite, 1 Bedroom, Non Smoking | Hypo-allergenic bedding, down duvets, pillow-top beds, in-room safe
Radisson Hotel Santo Domingo

Radisson Hotel Santo Domingo

Radisson Hotel Santo Domingo
4.5 star property
Ensanche Naco, 4.4 km from San Antón
8.6 out of 10, Excellent, (1003)
"The Breakfast was fresh and nice"
United States
Jeudienne
The price is 2.265.121 ₫
2.899.354 ₫ total
includes taxes & fees
20 Dec - 21 Dec
Radisson Hotel Santo Domingo
2 outdoor pools, free pool cabanas, pool umbrellas
Dominican Fiesta Hotel

Dominican Fiesta Hotel

Dominican Fiesta Hotel
4.0 star property
Los Cacicazgos, 9.9 km from San Antón
8.0 out of 10, Very good, (2578)
"The staff were friendly, and approachable, great foods."
Canada
Antoine
The price is 2.185.097 ₫
2.796.924 ₫ total
includes taxes & fees
30 Dec - 31 Dec
Dominican Fiesta Hotel
Outdoor pool, open 7:00 AM to 9:00 PM, pool loungers
Embassy Suites by Hilton Santo Domingo

Embassy Suites by Hilton Santo Domingo

Embassy Suites by Hilton Santo Domingo
4.0 star property
4.4 km from San Antón
9.4 out of 10, Exceptional, (1000)
"The room, breakfast, restaurant, and employees were excellent."
United States
William Cardona
The price is 3.373.696 ₫
4.318.330 ₫ total
includes taxes & fees
20 Dec - 21 Dec
Embassy Suites by Hilton Santo Domingo
Outdoor pool, pool umbrellas, pool loungers
Sheraton Santo Domingo Hotel

Sheraton Santo Domingo Hotel

Sheraton Santo Domingo Hotel
4.0 star property
Gascue, 2.1 km from San Antón
8.8 out of 10, Excellent, (1000)
"Safe and quiet. "
United States
Darlene
The price is 3.189.197 ₫
4.082.172 ₫ total
includes taxes & fees
13 Dec - 14 Dec
Sheraton Santo Domingo Hotel
Superior Premium Level Room | Room amenity
Barceló Santo Domingo

Barceló Santo Domingo

Barceló Santo Domingo
4.0 star property
Miraflores, 2.8 km from San Antón
8.6 out of 10, Excellent, (1359)
"Great Food "
United States
Juana
The price is 1.907.794 ₫
2.441.976 ₫ total
includes taxes & fees
12 Jan - 13 Jan 2026
Barceló Santo Domingo
Exterior
Hodelpa Caribe Colonial

Hodelpa Caribe Colonial

Hodelpa Caribe Colonial
3.5 star property
Ciudad Colonial, 0.5 km from San Antón
8.8 out of 10, Excellent, (1005)
"Perfect hotel great breakfast good services "
United States
Howard
The price is 2.440.698 ₫
3.124.093 ₫ total
includes taxes & fees
8 Jan - 9 Jan 2026
Hodelpa Caribe Colonial
Exterior
Mosquito Boutique Hotel Zona Colonial

Mosquito Boutique Hotel Zona Colonial

Mosquito Boutique Hotel Zona Colonial
3.5 star property
Ciudad Colonial, 0.4 km from San Antón
8.8 out of 10, Excellent, (256)
"Amazing services on our stay. "
United States
Gilbert
The price is 2.343.281 ₫
2.999.400 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Mosquito Boutique Hotel Zona Colonial
Restaurant
Homewood Suites by Hilton Santo Domingo, Dominican Republic

Homewood Suites by Hilton Santo Domingo, Dominican Republic

Homewood Suites by Hilton Santo Domingo, Dominican Republic
3.5 star property
Evaristo Morales, 5.9 km from San Antón
9.4 out of 10, Exceptional, (700)
"Good place to stay , close to the blue mall "
United States
Fernando
The price is 3.349.049 ₫
4.286.888 ₫ total
includes taxes & fees
7 Jan - 8 Jan 2026
Homewood Suites by Hilton Santo Domingo, Dominican Republic
Standard Room, 1 King Bed | Premium bedding, in-room safe, desk, laptop workspace
Weston Suites & Hotel

Weston Suites & Hotel

Weston Suites & Hotel
3.5 star property
La Julia, 5.1 km from San Antón
7.6 out of 10, Good, (1000)
"nice hotel "
United States
Robert
The price is 2.401.205 ₫
3.073.648 ₫ total
includes taxes & fees
18 Dec - 19 Dec
Weston Suites & Hotel
Superior Apartment, 2 Bedrooms | View from room
Parco del caribe

Parco del caribe

Parco del caribe
3.0 star property
29.3 km from San Antón
9.0 out of 10, Wonderful, (240)
"Clean bedroom the staff was friendly "
United States
Efrain
The price is 1.265.136 ₫
1.492.861 ₫ total
includes taxes & fees
13 Dec - 14 Dec
Parco del caribe
Reception
Hotel Vicentina

Hotel Vicentina

Hotel Vicentina
3.0 star property
29.5 km from San Antón
8.6 out of 10, Excellent, (728)
"The staff Amazing & The Rooms As Well!!"
United States
diego
Hotel Vicentina
Front of property
Cataleya Hotel

Cataleya Hotel

Cataleya Hotel
3.0 star property
Ciudad Colonial, 0.3 km from San Antón
8.6 out of 10, Excellent, (329)
"Very clean and the staff very helpful I would stay there again. It’s also very safe area. I enjoy the breakfast. It was very nice."
United States
CARMEN
The price is 1.317.586 ₫
1.686.584 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Cataleya Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in San Antón

Find the best San Antón areas for the activities you enjoy most.
Fort Ozama which includes heritage elements

Zona Colonial

Zona Colonial is popular for its abundant dining options, and if you're looking for more to see and do, you might think about a trip to Calle El Conde or Santa Maria la Menor Cathedral.

Downtown Santo Domingo

Consider exploring the abundant dining options in Downtown Santo Domingo. If sightseeing is on the list, Acropolis Center is a top attraction. Hop on the metro at Freddy Beras Goico Station or Juan Ulises Garcia Station to see more of the area.

Piantini

Unique features of Piantini include the shopping and restaurants. Make a stop by Blue Mall or Acropolis Center while you're exploring the area.

Alcazar de Colon showing a square or plaza and a city

Ciudad Colonial

If you're spending some time in Ciudad Colonial, Calle El Conde and Santa Maria la Menor Cathedral are top sights worth seeing.

Bella Vista

While there might not be top attractions in Bella Vista, you can explore the larger area and discover places like Acropolis Center and Bella Vista Mall.

Top San Antón Hotel Reviews

Explore a world of travel with Expedia

Frequently asked questions

What is San Antón like?
Travellers will be sure to find plenty to entertain them in Santo Domingo's San Antón neighbourhood. Make sure that you visit Fuerte de Santa Bárbara and Amber World Museum as part of your San Antón travel plans.
How many hotels are there in San Antón?
Expedia has 21 hotels and other accommodation options in San Antón to choose from, making this an ideal home base for exploring the greater Santo Domingo area.
If I need to cancel my hotel reservation in San Antón, will I receive a refund?
Yes! The majority of hotel bookings are refundable provided that you cancel prior to the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If you booked a non-refundable reservation, it might still be possible to cancel it and be given a refund within a 24-hour period of your booking. Put your dates in and click on "Search", then use the "fully refundable" filter to review the top deals on offer in San Antón.
What can I see and do in this Santo Domingo neighbourhood?
San Antón's sights and attractions like Amber World Museum, Museo Mundo del Ambar / Amber World Museum and Museo del Duarte offer insight into the local culture. Fuerte de Santa Bárbara and Iglesia de Santa Bárbara are also a couple of places to visit in the neighbourhood. Museo del Ron y la Caña, Casa del Cordón and Chinatown are just a few of the places to visit in and around San Antón. When you're sightseeing in Santo Domingo, Centro Cultural de las Telecomunicaciones and Plaza de España are also worth a stop.