Search Hotels in San Antonio, Cusco

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
12 Dec - 13 Dec
Tomorrow
13 Dec - 14 Dec
This weekend
12 Dec - 14 Dec
Next weekend
19 Dec - 21 Dec

Filter by

Guest rating
Guest rating
Star rating

Our top choices for San Antonio hotels

Living area
Las Margaritas Apart

Las Margaritas Apart

Las Margaritas Apart
4.0 star property
San Antonio
The price is 1.670.069 ₫
1.670.069 ₫ total
14 Dec - 15 Dec
Las Margaritas Apart
Front of property
Hotel Inka Pisac

Hotel Inka Pisac

Hotel Inka Pisac
3.5 star property
15.7 km from San Antonio
9.0 out of 10, Wonderful, (40)
"I loved the view from the balcony!"
United States
Cathy
Hotel Inka Pisac
Interior detail
Ayenda Casa Escondida San Cristobal Premium

Ayenda Casa Escondida San Cristobal Premium

Ayenda Casa Escondida San Cristobal Premium
2.5 star property
San Cristóbal, 6.3 km from San Antonio
8.8 out of 10, Excellent, (76)
"Good location and kind staff"
United States
ernesto
The price is 842.788 ₫
842.788 ₫ total
17 Dec - 18 Dec
Ayenda Casa Escondida San Cristobal Premium
Interior
Apu Mountain Lodge

Apu Mountain Lodge

Apu Mountain Lodge
3.5 star property
4.6 km from San Antonio
10.0 out of 10, Exceptional, (12)
"The concierge was a most gracious host. He went out of his way make us welcome. It was a welcome relief that he spoke perfect english."
United States
Dennis
Apu Mountain Lodge
Breakfast, lunch and dinner served
Casa Esmeralda By Katari

Casa Esmeralda By Katari

Casa Esmeralda By Katari
3.5 star property
Coripata, 5.6 km from San Antonio
9.2 out of 10, Wonderful, (265)
"Nice place to stay in Cusco with great people and in walking distance from all main things ."
United Kingdom
Ghighilan Alexandru
The price is 1.151.630 ₫
1.266.793 ₫ total
4 Jan - 5 Jan 2026
Casa Esmeralda By Katari
Exterior
Quechua Hotel cusco

Quechua Hotel cusco

Quechua Hotel cusco
3.5 star property
Cusco Historic Center, 6.4 km from San Antonio
8.6 out of 10, Excellent, (83)
"Very good service "
Canada
Huixia
The price is 2.530.272 ₫
2.530.272 ₫ total
13 Dec - 14 Dec
Quechua Hotel cusco
Lobby sitting area
Polo Corporativo San Sebastian

Polo Corporativo San Sebastian

Polo Corporativo San Sebastian
3.0 star property
2 km from San Antonio
8.0 out of 10, Very good, (171)
"The room was not ready we check. We checked in late due to flight delay No towels - no phone to call down stairs we had to go down a few times. Would not give us late check out Just bad experience "
United States
Guido Albero
The price is 1.843.030 ₫
1.843.030 ₫ total
13 Dec - 14 Dec
Polo Corporativo San Sebastian
Front of property
Mayu Boutique Hotel

Mayu Boutique Hotel

Mayu Boutique Hotel
2.5 star property
San Cristóbal, 6.3 km from San Antonio
8.4 out of 10, Very good, (52)
"Great stay!"
United States
Regina
Mayu Boutique Hotel
Junior Suite | Free WiFi
Quechua Plaza Hotel

Quechua Plaza Hotel

Quechua Plaza Hotel
2.5 star property
Cusco Historic Center, 5.7 km from San Antonio
9.4 out of 10, Exceptional, (6)
"Las habitaciones son súper acogedoras, con alfombra y calefacción que hacen que todo sea muy cómodo.Ademas tuvimos agua caliente durante toda nuestra estadía El desayuno buffet es delicioso y cada día sorprenden con un platito de fondo distinto 🤩. El personal es muy amable y siempre atento; incluso el mismo administrador, el joven Jesús Navia, nos atendió personalmente y desde el primer momento nos hizo sentir como en casa. ¡Definitivamente volvería sí o síii! 🙌✨"
Mexico
Dayanne Stephannie
The price is 3.949.350 ₫
3.949.350 ₫ total
13 Dec - 14 Dec
Quechua Plaza Hotel
Interior
Amaru Inca

Amaru Inca

Amaru Inca
3.0 star property
San Blas, 5.9 km from San Antonio
9.2 out of 10, Wonderful, (359)
"Great location and the staff was very helpful. "
United States
Cassandra
The price is 2.106.320 ₫
2.106.320 ₫ total
7 Jan - 8 Jan 2026
Amaru Inca
Restaurant
JW Marriott El Convento Cusco

JW Marriott El Convento Cusco

JW Marriott El Convento Cusco
5.0 star property
Cusco Historic Center, 5.8 km from San Antonio
9.6 out of 10, Exceptional, (1000)
"We really liked the breakfast and the staffs were very helpful and friendly "
United States
Min
The price is 6.634.908 ₫
8.377.888 ₫ total
11 Jan - 12 Jan 2026
JW Marriott El Convento Cusco
Courtyard
Cusco Plaza Saphi

Cusco Plaza Saphi

Cusco Plaza Saphi
3.0 star property
Cusco Historic Center, 6.5 km from San Antonio
8.2 out of 10, Very good, (119)
"Great breakfast, clean room, quiet, very centrally located"
United States
Anne
The price is 1.594.550 ₫
1.754.005 ₫ total
15 Dec - 16 Dec
Cusco Plaza Saphi
Terrace/patio
Huascaran Casa Boutique Cusco

Huascaran Casa Boutique Cusco

Huascaran Casa Boutique Cusco
3.0 star property
San Blas, 5.8 km from San Antonio
8.6 out of 10, Excellent, (414)
"Wonderful staff and a great place to stay! "
United States
Olivia
Huascaran Casa Boutique Cusco
Hypo-allergenic bedding, desk, laptop workspace, iron/ironing board
Estancia San Pedro Hotel

Estancia San Pedro Hotel

Estancia San Pedro Hotel
3.0 star property
Cusco Historic Center, 6.5 km from San Antonio
8.8 out of 10, Excellent, (93)
"Good hotel, I would stay again."
United States
Melanie
The price is 1.566.312 ₫
1.566.312 ₫ total
9 Jan - 10 Jan 2026
Estancia San Pedro Hotel
Terrace/patio
Palacio Manco Capac by Ananay Hotels

Palacio Manco Capac by Ananay Hotels

Palacio Manco Capac by Ananay Hotels
4.5 star property
San Cristóbal, 6.4 km from San Antonio
9.6 out of 10, Exceptional, (325)
"Beautiful rooms and grounds. Staff are incredibly friendly and helpful. Breakfast is fantastic. "
United Kingdom
Ryan
The price is 2.569.500 ₫
2.826.450 ₫ total
11 Jan - 12 Jan 2026
Palacio Manco Capac by Ananay Hotels
Front of property – evening/night
Hotel Paradis Suite - Cusco

Hotel Paradis Suite - Cusco

Hotel Paradis Suite - Cusco
3.0 star property
La Florida, 3.7 km from San Antonio
8.0 out of 10, Very good, (142)
"This hotel is perfect! Clean, comfy beds, safe, the food is great and it’s very convenient for everything. I love staying here "
United States
Romy
Hotel Paradis Suite - Cusco
Superior Room | Premium bedding, down duvets, in-room safe, desk
Antigua Casona San Blas

Antigua Casona San Blas

Antigua Casona San Blas
4.0 star property
San Blas, 5.7 km from San Antonio
10.0 out of 10, Exceptional, (1005)
"Amazing staff, property, restaurant and location. 100% recommend this hotel"
United States
Cameron
The price is 5.835.823 ₫
5.835.823 ₫ total
5 Jan - 6 Jan 2026
Antigua Casona San Blas
Interior
Hotel & Mirador Los Apus

Hotel & Mirador Los Apus

Hotel & Mirador Los Apus
3.0 star property
San Blas, 6.1 km from San Antonio
8.8 out of 10, Excellent, (276)
"Great hotel, away from the noisy streets of Cusco. Very comfortable and great staff"
Canada
Renee
The price is 2.172.143 ₫
2.389.357 ₫ total
18 Dec - 19 Dec
Hotel & Mirador Los Apus
Interior
Eco Bunnu Inn

Eco Bunnu Inn

Eco Bunnu Inn
2.5 star property
Lucrepata, 5.4 km from San Antonio
9.2 out of 10, Wonderful, (82)
"Great service and kind people in the lobby "
United Kingdom
Alexander
Eco Bunnu Inn
Exclusive Twin Room, Balcony, Tower | Terrace/patio
Prisma Hotel

Prisma Hotel

Prisma Hotel
3.0 star property
Cusco Historic Center, 5.8 km from San Antonio
8.8 out of 10, Excellent, (79)
"Good place to stay, everything "
Canada
Raghu
Prisma Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in San Antonio

Find the best San Antonio areas for the activities you enjoy most.
La Merced Church showing a city

Cusco Historic Center

Cusco Historic Center is known for its popular shops, and with sights like Santa Catalina Convent and Coricancha, you won't get bored spending a day wandering around this part of Cusco.

San Blas showing a city

San Blas

San Blas is noteworthy for its shopping, and you can make a stop at top attractions like Plaza San Blas and San Blas Church.

San Cristóbal

While visiting San Cristóbal, you might make a stop by sights like Pre-Columbian Art Museum and Plaza de las Nazarenas.

Santiago

If you're looking for some top things to see and do in Santiago and surrounding area, you can visit Ttio Market and Santiago Plaza.

Santa Monica

While Santa Monica may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Real Plaza Cusco and Ttio Market.

Top San Antonio Hotel Reviews

Kantu Hotel

Kantu Hotel

10/10 Excellent
"Property was clean, staff was friendly and helpful and breakfast was delicious "
Natalia 2-night trip
Posted 4 days ago
Kantu Hotel

Explore a world of travel with Expedia

Frequently asked questions

What is San Antonio like?
Travellers will be sure to find plenty to entertain them in Cusco's San Antonio neighbourhood.
If I need to cancel my hotel reservation in San Antonio, will I receive a refund?
Yes! You'll find that most hotel bookings are fully refundable if you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you have a reservation that's non-refundable, you might be able to cancel it and receive a refund within a 24-hour period of booking. Enter your dates, click on "Search", then use the "fully refundable" filter to get the best options available in San Antonio.
What is there to do in this Cusco neighbourhood?
A few places to visit in the area around San Antonio include Wayna Tawqaray Archaeological Site, Agua Buena Recreational Park and Qotakalli Archaeological Site. When you're sightseeing in Cusco, Incan Citadel and Real Plaza Cusco are also worth a stop.