San Antonio Holidays

Book a Hotel + Flight or Car together to unlock savings

Where to stay in San Antonio

Find the best San Antonio areas and neighborhoods for the activities you enjoy most. Learn more about San Antonio
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Rufina Alfaro

1 out of top 10 points of interest in this area

Rufina Alfaro might not have many top sights, but Metromall Panama and Los Pueblos Commercial Center are two attractions nearby that you can check out.

Find hotels in Rufina Alfaro

Top hotels in San Antonio

Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall

4 out of 5
Avenida Domingo Diaz via Tocumen San Miguelito Panama
Fully refundableReserve now, pay when you stay
The price is 2.657.919 ₫ per night from 6 Feb to 7 Feb
2.657.919 ₫
2.923.711 ₫ total
6 Feb - 7 Feb
includes taxes & fees
8.8/10 Excellent! (1,005 reviews)
Food was great Everything was wonderful

Reviewed on 13 Jan 2026

Courtyard by Marriott Panama Metromall
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella Panama City Panama
Fully refundableReserve now, pay when you stay
The price is 3.040.126 ₫ per night from 4 Feb to 5 Feb
3.040.126 ₫
3.344.139 ₫ total
4 Feb - 5 Feb
includes taxes & fees
9/10 Wonderful! (4,823 reviews)
The bed wasn’t comfortable and the windows were always blurry due to the humidity. Couldn’t see the city like I wanted to.

Reviewed on 12 Jan 2026

Hotel Riu Plaza Panama
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

4 out of 5
Ave. Domingo Diaz Tocumen Panama
Fully refundable
The price is 2.890.470 ₫ per night from 29 Jan to 30 Jan
2.890.470 ₫
3.179.517 ₫ total
29 Jan - 30 Jan
includes taxes & fees
8.4/10 Very Good! (2,400 reviews)
Very convenient and close to the airport

Reviewed on 12 Jan 2026

Crowne Plaza Panama Airport by IHG
See all 1,673 properties in San Antonio
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a San Antonio holiday package cost?
Choose from any combination of car rentals, flights and hotels, and you can be holidaying in San Antonio from just . And the more you bundle, the more cash you save. The holiday of your dreams has never been more affordable.
How do I get a cheap travel package to San Antonio?
Our San Antonio holiday packages promise plenty of savings for the savvy traveller. For the best deal, simply combine your flights, hotels and extras (including tours) into one neat package. But great bargains are only the start of your next unforgettable adventure. Book with Expedia and and you'll have over 550 airlines and 1null000null000 hotel options across the globe to pick from. Whatever your budget or style, there's a holiday package that's perfect for you.
Where should I stay in San Antonio?
If you're interested in visiting Metromall Panama, give commuting a miss and book a hotel nearby. It's one of the best attractions in this neighbourhood.
What are the top hotels in San Antonio?
Dumas Villas is one of San Antonio's most popular properties. Lock in a room here and you'll slumber peacefully knowing you're in capable hands.
How far in advance should I book my San Antonio holiday?
Search Expedia to compare international airfares ASAP. You can usually purchase a seat up to 12 months in advance. If you can't see your preferred air carrier, or you've left things to the last minute, don't stress. Cheap fares to San Antonio sometimes occur within weeks of the date of departure.
What does an Expedia San Antonio travel package include?
From airfares and hotels to rental cars, Expedia can help you put together a San Antonio package that's right for you. Holidaying for a few weeks? Check out a rental car, flight and hotel bundle. If your break is short, a hotel and flight deal may be more your style. Experiences can also be added once you've made your booking. Our holiday packages make it a cinch to plan and save.
What should I know before booking a San Antonio travel package?
So many places to explore, so many things to do. With a package, you can check more of them off your list. Bundle your hotels, flights and rental cars and get set to save.
Can I choose my airline with a San Antonio Expedia holiday package?
Yes — that's the beauty of an Expedia holiday package. You're in control. We have more than 550 airline partners all over the world, so you have lots of choice when putting together your San Antonio getaway.
If I'm not able to travel, can I cancel my San Antonio holiday package?
We totally get it — unexpected stuff happens. If you've booked a San Antonio holiday package and need to cancel or amend it, we can help. We recommend browsing our Customer Service Portal first for information. But generally, if you've booked your package within 24 hours, you may be able to cancel or amend your itinerary for free. If it's been longer than 24 hours, your hotel, airline or car rental company may impose a fee.

Popular places to visit

Metromall Panama

During your trip to San Miguelito, you can do some window-shopping at Metromall Panama. Make time to visit the area's casinos or simply enjoy its top-notch restaurants.

Metromall Panama

Templo Bahá'í

You can find out about the history of San Miguelito with a stop at Templo Bahá'í. Stroll along the seaside or visit the casinos in this vibrant area.

Templo Bahá'í