Search Hotels in San Antonio, San Miguelito

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12 Dec - 13 Dec
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13 Dec - 14 Dec
This weekend
12 Dec - 14 Dec
Next weekend
19 Dec - 21 Dec

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Our top choices for San Antonio hotels

Outdoor pool, pool umbrellas, pool loungers
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG
4.0 star property
6.1 km from San Antonio
8.4 out of 10, Very good, (2319)
"Spacious room, clean, good breakfast "
United States
Juan
The price is 2.896.190 ₫
3.185.809 ₫ total
includes taxes & fees
18 Dec - 19 Dec
Crowne Plaza Panama Airport by IHG
Living area
ORHO HOTEL BOUTIQUE PANAMA Airport

ORHO HOTEL BOUTIQUE PANAMA Airport

ORHO HOTEL BOUTIQUE PANAMA Airport
2.0 star property
5.7 km from San Antonio
9.0 out of 10, Wonderful, (35)
"It was a cool unique antique place that had modern touches. The staff was very friendly and helpful. Will definitely stay again. "
United States
Clarissa
The price is 3.159.480 ₫
4.101.005 ₫ total
includes taxes & fees
13 Dec - 14 Dec
ORHO HOTEL BOUTIQUE PANAMA Airport
47-inch flat-screen TV with cable channels, TV
Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo
4.0 star property
15.8 km from San Antonio
9.0 out of 10, Wonderful, (1003)
"Excellent hotel , good breakfast, great location, would highly recommend "
United States
Glen
The price is 5.259.473 ₫
5.785.420 ₫ total
includes taxes & fees
16 Dec - 17 Dec
Central Hotel Panama Casco Viejo
Front of property
La Concordia Boutique Hotel

La Concordia Boutique Hotel

La Concordia Boutique Hotel
4.0 star property
16 km from San Antonio
9.6 out of 10, Exceptional, (194)
"Beautiful room Good location"
United States
Karla
The price is 5.858.956 ₫
6.444.852 ₫ total
includes taxes & fees
18 Dec - 19 Dec
La Concordia Boutique Hotel
Reception
Hotel Coral Suites

Hotel Coral Suites

Hotel Coral Suites
3.5 star property
12.5 km from San Antonio
9.0 out of 10, Wonderful, (1002)
"Great place for the price. "
United States
Ryan
The price is 1.753.511 ₫
1.928.862 ₫ total
includes taxes & fees
4 Jan - 5 Jan 2026
Hotel Coral Suites
View from property
Waldorf Astoria Panama

Waldorf Astoria Panama

Waldorf Astoria Panama
5.0 star property
13.1 km from San Antonio
9.0 out of 10, Wonderful, (1001)
"I loved everything about my stay "
United States
Stephanie
The price is 5.807.651 ₫
6.388.416 ₫ total
includes taxes & fees
3 Jan - 4 Jan 2026
Waldorf Astoria Panama
3 outdoor pools, pool umbrellas, pool loungers
The Westin Playa Bonita Panama

The Westin Playa Bonita Panama

The Westin Playa Bonita Panama
5.0 star property
23.4 km from San Antonio
8.0 out of 10, Very good, (1002)
"Our stay was very nice, the service the hotel provides is wonderful, I highly recommend it"
United States
Mayra Alexandra Montes
The price is 5.239.471 ₫
5.763.418 ₫ total
includes taxes & fees
15 Dec - 16 Dec
The Westin Playa Bonita Panama
Outdoor pool, open 7:00 AM to 10:30 PM, free pool cabanas
Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino
4.0 star property
4.5 km from San Antonio
8.6 out of 10, Excellent, (1851)
"Clean room and friendly staff "
United States
Delcides
The price is 3.292.454 ₫
3.621.699 ₫ total
includes taxes & fees
13 Dec - 14 Dec
Riande Aeropuerto Hotel & Casino
Exterior
TRYP by Wyndham Panamá Centro

TRYP by Wyndham Panamá Centro

TRYP by Wyndham Panamá Centro
3.5 star property
12.7 km from San Antonio
9.2 out of 10, Wonderful, (1001)
"Great staff and the room was very clean. "
United States
JOHNNY
The price is 2.294.572 ₫
2.524.161 ₫ total
includes taxes & fees
19 Dec - 20 Dec
TRYP by Wyndham Panamá Centro
Aerial view
Gamboa Rainforest Reserve

Gamboa Rainforest Reserve

Gamboa Rainforest Reserve
3.5 star property
28.2 km from San Antonio
7.8 out of 10, Good, (663)
"Beautiful place to stay for one night. A little over priced for Panama but the service and the food were excellent. "
Canada
Dan
The price is 3.293.758 ₫
3.623.134 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Gamboa Rainforest Reserve
Exterior
Aloft Panama

Aloft Panama

Aloft Panama
3.5 star property
10.3 km from San Antonio
8.8 out of 10, Excellent, (892)
"The staff was very friendly, rooms were clean and modern."
United States
Greg
The price is 3.080.493 ₫
3.388.542 ₫ total
includes taxes & fees
21 Dec - 22 Dec
Aloft Panama
Outdoor pool
Ramada Panama Centro Via Argentina

Ramada Panama Centro Via Argentina

Ramada Panama Centro Via Argentina
3.0 star property
12.5 km from San Antonio
7.4 out of 10, Good, (267)
"Hotel staff and rooms were good , great location "
United States
Cornelly
The price is 2.237.965 ₫
2.461.762 ₫ total
includes taxes & fees
16 Dec - 17 Dec
Ramada Panama Centro Via Argentina
Front of property
Novotel Panama City

Novotel Panama City

Novotel Panama City
4.0 star property
11.9 km from San Antonio
9.2 out of 10, Wonderful, (1015)
"Great service, big room, solid breakfasts.. all at good price."
Canada
Nicholas
The price is 2.748.748 ₫
3.023.623 ₫ total
includes taxes & fees
14 Dec - 15 Dec
Novotel Panama City
Front of property – evening/night
Principe Hotel and Suites

Principe Hotel and Suites

Principe Hotel and Suites
3.0 star property
12.2 km from San Antonio
9.0 out of 10, Wonderful, (1587)
"Room was ok ac good staff was good "
United States
Kerro
The price is 1.316.448 ₫
1.448.093 ₫ total
includes taxes & fees
27 Dec - 28 Dec
Principe Hotel and Suites
Couples treatment room(s), sauna, steam room, body treatments
Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel
5.0 star property
12.8 km from San Antonio
9.4 out of 10, Exceptional, (1001)
"Love this hotel. Busy area, but hotel and restaurant make up for it."
United States
Allen
The price is 5.297.711 ₫
5.827.482 ₫ total
includes taxes & fees
3 Jan - 4 Jan 2026
Bristol Panama, a Registry Collection Hotel
Breakfast, lunch, dinner served; international cuisine
Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall
4.0 star property
Cerro Viento, 1.4 km from San Antonio
8.8 out of 10, Excellent, (1004)
"Conveniently located near the airport and major shopping outlets."
United States
Greg
The price is 2.663.178 ₫
2.929.495 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Courtyard by Marriott Panama Metromall
Suite, 1 Bedroom, Golf View (Terrace) | Premium bedding, minibar, in-room safe, desk
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
4 km from San Antonio
9.6 out of 10, Exceptional, (638)
"As usual the stay was amazing in this hotel"
United States
Jose
The price is 6.101.746 ₫
6.711.921 ₫ total
includes taxes & fees
14 Dec - 15 Dec
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Private kitchen
Mahogany Suites

Mahogany Suites

Mahogany Suites
2.0 star property
20.1 km from San Antonio
10.0 out of 10, Exceptional, (1)
"Todo ok"
Colombia
Juan
The price is 3.080.493 ₫
3.388.542 ₫ total
includes taxes & fees
20 Dec - 21 Dec
Mahogany Suites
Outdoor pool, open 9:00 AM to 9:00 PM, pool loungers
Hospedium Princess Hotel Panama

Hospedium Princess Hotel Panama

Hospedium Princess Hotel Panama
3.5 star property
12.3 km from San Antonio
7.6 out of 10, Good, (695)
"The breakfast was great, I love the pool."
United States
Estefani
The price is 1.355.417 ₫
1.490.959 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Hospedium Princess Hotel Panama
Daily full breakfast for a fee
Hotel La Compañía Casco Antiguo

Hotel La Compañía Casco Antiguo

Hotel La Compañía Casco Antiguo
4.5 star property
15.8 km from San Antonio
9.8 out of 10, Exceptional, (258)
"Great location!"
United States
Erik
The price is 8.477.938 ₫
9.325.732 ₫ total
includes taxes & fees
24 Dec - 25 Dec
Hotel La Compañía Casco Antiguo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in San Antonio

Find the best San Antonio areas for the activities you enjoy most.

Cerro Viento

Shopping and restaurants are notable features of Cerro Viento. You might consider stopping by Metromall Panama while you're exploring the neighbourhood.

José Domingo Espinar

José Domingo Espinar might not have many top sights, but Estadio Rommel Fernandez and Metromall Panama are two attractions nearby that you can check out.

Rufina Alfaro

Rufina Alfaro might not have many top sights, but Metromall Panama and Los Pueblos Commercial Center are two attractions nearby that you can check out.

Victoriano Lorenzo

If you're looking for some top things to see and do in Victoriano Lorenzo and surrounding area, you can visit Panama Viejo and Estadio Rommel Fernandez.

Amelia Denis de Icaza

While there might not be top attractions in Amelia Denis de Icaza, you can explore the larger area and discover places like El Dorado Mall and Panama Viejo.

Top San Antonio Hotel Reviews

Hyatt Regency Panama City

Hyatt Regency Panama City

10/10 Excellent
"The hotel was stunning and christmas festive. It smelled great. The room was beautiful, the hospitality was great. I was suprised with a birthday treat to my door and a card which was super sweet and an excellent touch. Everything was clean. Room service made my bed and changed my towels everyday. Staff was kind and helpful even with the language barrier( I practiced communicating in Spanish). Check-in and check- out was easy and quick. My birthday accommodations were amazing. I was very thankful and comfortable. "
Re'neisha 4-night trip
Posted 7 days ago
Hyatt Regency Panama City

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Frequently asked questions

What's it like in San Antonio?
San Antonio is a neighbourhood that travellers like for its shopping and gardens.
If I need to cancel my hotel reservation in San Antonio, will I receive a refund?
Yes, most hotel reservations are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you have a non-refundable reservation, you might still have the option to cancel and get a refund within a 24-hour period of booking. Plug in your dates, click on "Search", then use the "fully refundable" filter to review the best options available in San Antonio.
What is there to do in this San Miguelito neighbourhood?
Metromall Panama, Los Pueblos Commercial Center and Estadio Rommel Fernandez are just a few of the places to visit in and around San Antonio. While you're out sightseeing, Plaza de Francia and Atrio Mall are a couple of additional sights to visit in San Miguelito.