Search Hotels in San Antonio, San Miguelito

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14 Dec - 15 Dec
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15 Dec - 16 Dec
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19 Dec - 21 Dec
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26 Dec - 28 Dec

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Our top choices for San Antonio hotels

Outdoor pool, pool umbrellas, pool loungers
Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG
4.0 star property
6.1 km from San Antonio
8.4 out of 10, Very good, (2322)
"Spacious room, clean, good breakfast "
United States
Juan
The price is 2.893.770 ₫
3.183.147 ₫ total
includes taxes & fees
18 Dec - 19 Dec
Crowne Plaza Panama Airport by IHG
Exterior
ORHO HOTEL BOUTIQUE PANAMA Airport

ORHO HOTEL BOUTIQUE PANAMA Airport

ORHO HOTEL BOUTIQUE PANAMA Airport
2.0 star property
5.7 km from San Antonio
9.0 out of 10, Wonderful, (37)
"It was a cool unique antique place that had modern touches. The staff was very friendly and helpful. Will definitely stay again. "
United States
Clarissa
The price is 3.156.840 ₫
3.472.524 ₫ total
includes taxes & fees
15 Dec - 16 Dec
ORHO HOTEL BOUTIQUE PANAMA Airport
Outdoor pool, open 7:00 AM to 10:30 PM, free pool cabanas
Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino
4.0 star property
4.5 km from San Antonio
8.6 out of 10, Excellent, (1853)
"Clean room and friendly staff "
United States
Delcides
The price is 3.289.704 ₫
3.618.674 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Riande Aeropuerto Hotel & Casino
Outdoor pool, pool loungers
Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
5.0 star property
12.4 km from San Antonio
9.0 out of 10, Wonderful, (4663)
"Awesome great place to stay "
United States
Herbert
The price is 3.371.118 ₫
3.708.230 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Hotel Riu Plaza Panama
Food and drink
Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall
4.0 star property
Cerro Viento, 1.4 km from San Antonio
8.8 out of 10, Excellent, (1005)
"The hotel is conveniently close to the airport and shopping centres. "
United States
Samantha
The price is 2.660.953 ₫
2.927.049 ₫ total
includes taxes & fees
5 Jan - 6 Jan 2026
Courtyard by Marriott Panama Metromall
View from property
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
4 km from San Antonio
9.6 out of 10, Exceptional, (638)
"As usual the stay was amazing in this hotel"
United States
Jose
The price is 6.096.647 ₫
6.706.312 ₫ total
includes taxes & fees
19 Dec - 20 Dec
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Lobby
Hyatt Regency Panama City

Hyatt Regency Panama City

Hyatt Regency Panama City
4.5 star property
12.8 km from San Antonio
10.0 out of 10, Exceptional, (123)
"Great hotel fair price"
United States
Santiago
The price is 3.551.445 ₫
3.906.590 ₫ total
includes taxes & fees
20 Dec - 21 Dec
Hyatt Regency Panama City
50-inch LED TV with satellite channels
Arcadia Condo Suites

Arcadia Condo Suites

Arcadia Condo Suites
2.5 star property
6.2 km from San Antonio
9.4 out of 10, Exceptional, (161)
"Everything was great, helpful staff, great room , clean, excellent service!"
United States
Gregory Walter
The price is 1.631.034 ₫
3.009.520 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Arcadia Condo Suites
Garden
Radisson Hotel Panama Canal

Radisson Hotel Panama Canal

Radisson Hotel Panama Canal
4.5 star property
18.3 km from San Antonio
8.4 out of 10, Very good, (1002)
"Wonderful staff and easy checkin!"
United States
Kristin
The price is 1.833.598 ₫
2.016.958 ₫ total
includes taxes & fees
23 Dec - 24 Dec
Radisson Hotel Panama Canal
Terrace/patio
Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
3.5 star property
12.7 km from San Antonio
9.4 out of 10, Exceptional, (2134)
"Great location, friendly staff, excellent views and the best breakfast around."
Canada
Gregory
The price is 2.839.841 ₫
3.123.957 ₫ total
includes taxes & fees
1 Jan - 2 Jan 2026
Plaza Paitilla Inn Hotel
Front of property
Megapolis Hotel Panamá

Megapolis Hotel Panamá

Megapolis Hotel Panamá
4.5 star property
12.5 km from San Antonio
8.4 out of 10, Very good, (1269)
"Clean rooms, staff was amazing!!"
United States
Christopher
The price is 3.448.235 ₫
3.793.059 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Megapolis Hotel Panamá
Lobby
The Executive Hotel

The Executive Hotel

The Executive Hotel
3.5 star property
12.8 km from San Antonio
9.2 out of 10, Wonderful, (1005)
"Clean room, friendly staff, great breakfast daily. I would always recommend this hotel to my friends and family. "
United States
Roxanne Timolyn Thomas
The Executive Hotel
Living area
Magnolia Inn

Magnolia Inn

Magnolia Inn
2.0 star property
15.9 km from San Antonio
8.8 out of 10, Excellent, (412)
"Excelent location , friendly staff and cute hotel"
Canada
Renata
The price is 1.602.368 ₫
1.762.605 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Magnolia Inn
2 bars/lounges, gastropub
Riande Urban Hotel

Riande Urban Hotel

Riande Urban Hotel
3.5 star property
12.4 km from San Antonio
8.8 out of 10, Excellent, (1056)
"Good hotel and nice staff"
United States
Jose
The price is 2.212.551 ₫
2.433.806 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Riande Urban Hotel
Front of property – evening/night
Principe Hotel and Suites

Principe Hotel and Suites

Principe Hotel and Suites
3.0 star property
12.2 km from San Antonio
9.0 out of 10, Wonderful, (1588)
"Room was ok ac good staff was good "
United States
Kerro
The price is 1.315.348 ₫
1.446.883 ₫ total
includes taxes & fees
27 Dec - 28 Dec
Principe Hotel and Suites
Outdoor pool
Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino
4.0 star property
12.7 km from San Antonio
9.0 out of 10, Wonderful, (625)
"Very great hotel and service "
United States
Prakash
The price is 1.929.092 ₫
2.864.701 ₫ total
includes taxes & fees
15 Dec - 16 Dec
Waymore Hotel Spa & Casino
Outdoor pool, pool loungers
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott

Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
4.5 star property
11.9 km from San Antonio
8.8 out of 10, Excellent, (1003)
"Amazing amazing service"
United States
KFIR
The price is 4.182.813 ₫
4.601.094 ₫ total
includes taxes & fees
20 Dec - 21 Dec
Sortis Hotel, Spa & Casino, Autograph Collection by Marriott
Reception
MARINN Tropical Vibes Hotel

MARINN Tropical Vibes Hotel

MARINN Tropical Vibes Hotel
3.5 star property
18.8 km from San Antonio
8.2 out of 10, Very good, (185)
"Great location "
United States
itzel
The price is 1.620.511 ₫
1.782.562 ₫ total
includes taxes & fees
15 Dec - 16 Dec
MARINN Tropical Vibes Hotel
Exterior
Hotel Milan

Hotel Milan

Hotel Milan
3.0 star property
12.6 km from San Antonio
9.0 out of 10, Wonderful, (425)
"It was a very pleasant experience the hotel is located in a great neighborhood, staff were friendly and competent, secure property and parking, clean and decent accommodations, especially at the room price point. "
Canada
Roger
The price is 1.052.280 ₫
1.157.508 ₫ total
includes taxes & fees
16 Dec - 17 Dec
Hotel Milan
Daily buffet breakfast (PAB 21 per person)
Sheraton Grand Panama

Sheraton Grand Panama

Sheraton Grand Panama
4.0 star property
10.4 km from San Antonio
8.6 out of 10, Excellent, (992)
"Was amazing food was delicious and stay was great "
United States
Amanda
The price is 3.527.769 ₫
3.880.546 ₫ total
includes taxes & fees
9 Jan - 10 Jan 2026
Sheraton Grand Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in San Antonio

Find the best San Antonio areas for the activities you enjoy most.

Cerro Viento

Shopping and restaurants are notable features of Cerro Viento. You might consider stopping by Metromall Panama while you're exploring the neighbourhood.

José Domingo Espinar

José Domingo Espinar might not have many top sights, but Estadio Rommel Fernandez and Metromall Panama are two attractions nearby that you can check out.

Rufina Alfaro

Rufina Alfaro might not have many top sights, but Metromall Panama and Los Pueblos Commercial Center are two attractions nearby that you can check out.

Victoriano Lorenzo

If you're looking for some top things to see and do in Victoriano Lorenzo and surrounding area, you can visit Panama Viejo and Estadio Rommel Fernandez.

Amelia Denis de Icaza

While there might not be top attractions in Amelia Denis de Icaza, you can explore the larger area and discover places like El Dorado Mall and Panama Viejo.

Top San Antonio Hotel Reviews

Hyatt Regency Panama City

Hyatt Regency Panama City

10/10 Excellent
"The hotel was stunning and christmas festive. It smelled great. The room was beautiful, the hospitality was great. I was suprised with a birthday treat to my door and a card which was super sweet and an excellent touch. Everything was clean. Room service made my bed and changed my towels everyday. Staff was kind and helpful even with the language barrier( I practiced communicating in Spanish). Check-in and check- out was easy and quick. My birthday accommodations were amazing. I was very thankful and comfortable. "
Re'neisha 4-night trip
Posted 9 days ago
Hyatt Regency Panama City

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Frequently asked questions

What's it like in San Antonio?
San Antonio is a neighbourhood that travellers like for its shopping and gardens.
If I need to cancel my hotel reservation in San Antonio, will I receive a refund?
Yes, most hotel reservations are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you have a non-refundable reservation, you might still have the option to cancel and get a refund within a 24-hour period of booking. Plug in your dates, click on "Search", then use the "fully refundable" filter to review the best options available in San Antonio.
What is there to do in this San Miguelito neighbourhood?
Metromall Panama, Los Pueblos Commercial Center and Estadio Rommel Fernandez are just a few of the places to visit in and around San Antonio. While you're out sightseeing, Plaza de Francia and Atrio Mall are a couple of additional sights to visit in San Miguelito.