Find out about the history of San Cosme y Damian when you take a trip to Guarani Jesuit Ruins of San Cosme and San Damián. Take in the museums while you're in the area.
Visitors can enjoy all that San Cosme y Damian has to offer, including its museums. You'll find 18 Expedia hotels and other accommodation options in the larger area of Encarnacion.
What's the seasonal weather in San Cosme y Damian?
The hottest months are usually January and February, with an average temperature of 26°C, while the coldest months are July and June, with an average of 17°C. The rainiest months in San Cosme y Damian are October, November, May and April, with each month seeing an average of 198 mm of rainfall.
