San Francisco Holidays

Book a Hotel + Flight or Car together to unlock savings

Photo by Fabiola Tile

Where to stay in San Francisco

Find the best San Francisco areas and neighborhoods for the activities you enjoy most. Learn more about San Francisco
Default Image

Casco Viejo

3.5/5(3 area reviews)

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Metropolitan Cathedral of Panama or Interoceanic Canal Museum while you're exploring the area.

Find hotels in Casco Viejo

Top hotels in San Francisco

Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street, Panama City, Panama
Fully refundableReserve now, pay when you stay
The price is 3.516.236 ₫ per night from 10 Aug to 11 Aug
3.516.236 ₫
3.867.859 ₫ total
10 Aug - 11 Aug
includes taxes & fees
8.4/10 Very Good! (911 reviews)
"Me and my husband loved staying there! Superb hotel beyond international standards! The staff was so friendly and attentive. The hotel is gorgeous! The pool is amazing and so is the spa. The breakfast buffet is excellent. I only have the best words to describe this place! I hope to stay there when ..."

Reviewed on 26 Jul 2025

Sheraton Grand Panama
JW Marriott Panama

JW Marriott Panama

5 out of 5
Calle Punta Colon, Punta Pacifica, Panama City, Panama
Fully refundableReserve now, pay when you stay
The price is 5.549.675 ₫ per night from 16 Aug to 17 Aug
5.549.675 ₫
6.104.642 ₫ total
16 Aug - 17 Aug
includes taxes & fees
8.8/10 Excellent! (1,014 reviews)
"Great location to stay"

Reviewed on 27 Jul 2025

JW Marriott Panama
Ramada Plaza By Wyndham Panama Punta Pacífica

Ramada Plaza By Wyndham Panama Punta Pacífica

4 out of 5
Via Israel y Calle 71, San Francisco, Panama City, Panama
Fully refundableReserve now, pay when you stay
The price is 2.674.542 ₫ per night from 30 Aug to 31 Aug
2.674.542 ₫
2.941.996 ₫ total
30 Aug - 31 Aug
includes taxes & fees
9.4/10 Exceptional! (1,015 reviews)
"We liked how easy it was to get around to other places and the breakfast was good. We did not like the laundry service, they charged a price for each pieces of clothing like a dry cleaner instead by the bundle."

Reviewed on 27 Jul 2025

Ramada Plaza By Wyndham Panama Punta Pacífica
See all 1,505 properties in San Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a San Francisco holiday package cost?
Much less than you might think — from a low , in fact! By bundling hotels, flights and car rentals into a custom-built holiday package, your San Francisco escape is only clicks away.
How do I get a cheap travel package to San Francisco?
Lock in flights that suit your schedule, add a hotel to your booking and watch how much you save with a San Francisco holiday package. It's that easy! From flights and hotels to rental cars and activities, Expedia makes travelling on the cheap easy. And with more than 550 partner airlines and 1null000null000 hotel options around the globe to pick from, you'll never be short of choice.
Where should I stay in San Francisco?
Make sightseeing easy by staying near San Francisco's main attractions. Miraflores Locks and Metropolitan Cathedral of Panama are two which top many visitors' bucket lists.
What are the top hotels in San Francisco?
If this will be your first visit to San Francisco, secure a room at Sublime Apartment City Centre. Ph Boutique Quartier Atlapa or New Cosy Apartment Ocean View. Quartier Del Mar. Both hotels will make you feel at home and are popular options with lots of travellers.
How far in advance should I book my San Francisco holiday?
It can be hard to know when is the ideal time to book your trip to San Francisco. But typically the earlier you book, the lower the prices. Sometimes, you can reserve your flights and hotels up to a year prior to your departure date. If you're eager to escape on a last-minute getaway, no need to fret! There are unbeatable deals announced on Expedia every day.
What does an Expedia San Francisco travel package include?
That mostly depends on you. You can choose from a range of San Francisco packages, such as a hotel, rental car and flight. You can also book a hotel and a flight, or a flight and a rental car. Once you've made your booking, you can add the fun stuff like experiences and tours. Whatever your ideal San Francisco holiday looks like, you're sure to save!
What should I know before booking a San Francisco travel package?
So many places to go, so many things to see and do. With a travel package, you'll be able to afford more of them. Bundle your hotels, flights and rental cars and land big savings.
Can I choose my airline with a San Francisco Expedia holiday package?
Yes, definitely. Expedia has more than 550 airline partners to choose from worldwide. With such a huge range of choice, finding the ideal carrier to whisk you off to San Francisco won't be difficult.
If I'm not able to travel, can I cancel my San Francisco holiday package?
Your situation can change in a flash, so yes, you can. You may be able to amend or cancel your San Francisco holiday package for free if you've booked in the last 24 hours. For older bookings, you can still make changes, but your car rental company, airline or hotel may charge a fee. Need more information? Look up our Customer Service Portal. We'll help make sure your trip goes off without a hitch.

Popular places to visit

Multiplaza Pacific Mall

Multiplaza Pacific Mall

During your trip to Panama City, you can search for that perfect souvenir at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.

Multiplaza Pacific Mall
Cinta Costera

Cinta Costera

Explore the great outdoors at Cinta Costera, a lovely green space in Panama City. While you're in the area, stroll along the seaside.

Cinta Costera
Avenida Balboa

Avenida Balboa

You can browse for the perfect souvenirs at Avenida Balboa during your stay in Panama City. While you're in the area, wander around the natural setting.

Avenida Balboa